Improvement of the power to detect complex disease genes by regional inference procedures

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 785-789

  Goldin, Lynn R ^a   Chase, Gary A ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Error rates; Genome screening; Regional inference; Sib pair tests

Indexed keywords

CONFERENCE PAPER; ERROR; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; METHODOLOGY;

CHROMOSOME MAPPING; FEMALE; GENETIC DISEASES, INBORN; GENETIC SCREENING; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); MALE; MATCHED-PAIR ANALYSIS; NUCLEAR FAMILY; PREDICTIVE VALUE OF TESTS; PROBABILITY; REGRESSION ANALYSIS; SOFTWARE;

EID: 0031456689     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<785::AID-GEPI37>3.0.CO;2-K     Document Type: Conference Paper

References (6)

1. Goldgar DE (1990): Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 47:957-967
2. Goldin LR, Chase GA, King TM, Badner JA, Gershon ES (1995): Use of exact and adjusted liability scores to detect genes affecting common traits. Genet Epidemiol 12:765-769.
3. Haseman JK, Elston RC (1972): The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
4. Lander E, Kruglyak L (1995): Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11: 241-247.
5. S.A.G.E. (1992): Statistical Analysis for Genetic Epidemiology, Release 2.2. Computer program package available from the Department of Epidemiology and Biostatistics. Case Western Reserve University, Cleveland.
6. Terwilliger JD, Shannon WD, Lathrop GM, Nolan JP, Goldin LR, Chase GA, Weeks DE (in press): True and false positive peaks in genome-wide scans: application of length-biased sampling to linkage mapping. Am J Hum Genet.