Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis

Journal of Biological Chemistry

Volumn 273, Issue 6, 1998, Pages 3148-3151

  Justice, Michael C ^a   Hsu, Ming Jo ^a   Tse, Bruno ^a   Ku, Theresa ^a   Balkovec, James ^a   Schmatz, Dennis ^a   Nielsen, Jennifer ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; FUNGAL PROTEIN; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; GENETIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN SYNTHESIS INHIBITION; RIBOSOME; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ANTIBIOTICS, ANTIFUNGAL; FUNGAL PROTEINS; INDENES; PEPTIDE ELONGATION FACTOR 2; PEPTIDE ELONGATION FACTORS; RIBOSOMES; SACCHAROMYCES CEREVISIAE;

EID: 0032488918     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.6.3148     Document Type: Article

References (19)

1. Belfield, G. P., and Tuite, M. F. (1993) Mol. Microbiol. 9, 411-418
2. Hauser, D., and Sigg, H. P. (1971) Helv. Chim. Acta 54, 1178-1190
3. Coval, S. J., Puar, M. S., Phife, D. W., Terracciano, J. S., and Patel, M. (1995) J. Antibiot. (Tokyo) 48, 1171-1172
4. Sherman, F., Fink, G. R., and Hicks, J. B. (1986) Laboratory Course Manual for Methods in Yeast Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
5. Hussain, I., and Leibowitz, M. J. (1986) Gene (Amst.) 46, 13-26
6. Skogerson, L. (1979) Methods Enzymol. 60, 676-685
7. Collins, J. F., Raeburn, F., and Maxwell, E. S. (1971) J. Biol. Chem. 246, 1049-1064
8. Lauer, S. J., Burks, E., Irvin, J. D., and Ravel, J. M. (1984) J. Biol. Chem. 259, 1644-1648
9. Sikorski, R. S., and Hieter, P. (1989) Genetics 122, 19-28
10. Phan, L. D., Perentesis, J. P., and Bodley, J. W. (1993) J. Biol. Chem. 268, 8665-8668
11. Gietz, R. D., and Sugino, A. (1988) Gene (Amst.) 74, 527-534
12. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
13. Czworkowski, J., and Moore, P. B. (1996) Nucleic Acids Res. 54, 293-332
14. Bodley, J. W., Lin, L., Salas, M. L., and Tao, M. (1970) FEBS Lett. 11, 153-156
15. Jurnak, F. (1994) Structure 2, 785-788
16. Czworkowski, J., Wang, J., Steitz, T. A., and Moore, P. B. (1994) EMBO J. 13, 3661-3668
17. Evarsson, A., Brazhnikov, E., Garber, M., Zheltonosova, J., Chirgadze, Yu., Al-Karadaghi, S., and Liljas, A. (1994) EMBO J. 16, 3669-3677
18. Johanson, U., and Hughes, D. (1994) Gene (Amst.) 143, 55-59
19. Johanson, U., Evarsson, A., Liljas, A., and Hughes, D. (1996) J. Mol. Biol. 258, 420-432