Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-β-D-glucan synthase inhibitors

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 11, 1997, Pages 2471-2479

  Douglas, C M ^a   D'Ippolito, J A ^a,c   Shei, G J ^a   Meinz, M ^a   Onishi, J ^a   Marrinan, J A ^a   Li, W ^a   Abruzzo, G K ^a   Flattery, A ^a   Bartizal, K ^a   Mitchell, A ^b   Kurtz, M B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Columbia University ^*  (United States)

^c Chrysalis Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; 1,3 BETA GLUCAN SYNTHASE INHIBITOR; AMPHOTERICIN B; ANIDULAFUNGIN; ANTIFUNGAL AGENT; CASPOFUNGIN; ECHINOCANDIN B DERIVATIVE; FLUCONAZOLE; FLUCYTOSINE; ITRACONAZOLE; KETOCONAZOLE; L 733560; NYSTATIN; PNEUMOCANDIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; ENZYME INHIBITION; GENE DISRUPTION; GENE ISOLATION; GENE MAPPING; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE;

EID: 0030671386     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.11.2471     Document Type: Article

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