Efficacy of nikkomycin Z against experimental pulmonary blastomycosis

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 9, 1997, Pages 2026-2028

  Clemons, Karl V ^a   Stevens, David A ^b  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; CHITIN SYNTHASE; ITRACONAZOLE; NIKKOMYCIN Z;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ARTICLE; BLASTOMYCES DERMATITIDIS; BLASTOMYCOSIS; CELL SURVIVAL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; DRUG HALF LIFE; ENZYME INHIBITION; LUNG DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030771531     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.9.2026     Document Type: Article

References (8)

1. Arathoon, E. G., E. Brummer, and D. A. Stevens. 1989. Efficacy of itraconazole in blastomycosis in a murine model and comparison with ketoconazole. Mycoses 32(Suppl. 1):109-112.
2. Cabib, E. 1991. Differential inhibition of chitin synthetases 1 and 2 from Saccharomyces cerevisiae by polyoxin D and nikkomycins. Antimicrob. Agents Chemother. 35:170-173.
3. Clemons, K. V., L. H. Hanson, and D. A. Stevens. 1993. Activities of the triazole D0870 in vitro and against murine blastomycosis. Antimicrob. Agents Chemother. 37:1177-1179.
4. Clemons, K. V., and D. A. Stevens. 1991. Comparative efficacies of amphotericin B lipid complex and amphotericin B deoxycholate suspension against murine blastomycosis. Antimicrob. Agents Chemother. 35:2144-2146.
5. Ganer, A., E. Arathoon, and D. A. Stevens. 1987. Initial experience in therapy for progressive mycoses with itraconazole, the first clinically studied triazole. Rev. Infect. Dis. 9(Suppl. 1):S77-S86.
6. Hector, R. F., and K. Schaller. 1992. Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo. Antimicrob. Agents Chemother. 36:1284-1289.
7. Hector, R. F., B. L. Zimmer, and D. Pappagianis. 1990. Evaluation of nikkomycins X and Z in murine models of coccidioidomycosis, histoplasmosis, and blastomycosis. Antimicrob. Agents Chemother. 34:587-593.
8. Hostetler, J. S., L. H. Hanson, and D. A. Stevens. 1993. Effect of hydroxypropyl-β-cyclodextrin on efficacy of oral itraconazole in disseminated murine cryptococcosis. J. Antimicrob. Chemother. 32:459-463.