ATP dependence is not an intrinsic property of Na+/H+ exchanger NHE1: Requirement for an ancillary factor

American Journal of Physiology - Cell Physiology

Volumn 276, Issue 6 45-6, 1999, Pages

  Aharonovitz, Orit ^a   Demaurex, Nicolas ^a   Woodside, Michael ^a   Grinstein, Sergio ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Amiloride; Ghosts; pH regulation; Red blood cells

Indexed keywords

(3 METHYLSULFONYL 4 PIPERIDINOBENZOYL)GUANIDINE METHANESULFONATE; ADENOSINE TRIPHOSPHATE; AMILORIDE; CARRIER PROTEIN; DEOXYGLUCOSE; SODIUM PROTON EXCHANGE PROTEIN NHE1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PH; CONTROLLED STUDY; DOG; ERYTHROCYTE; ERYTHROCYTE GHOST; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SODIUM TRANSPORT;

EID: 0033000910     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.276.6.c1303     Document Type: Article

References (13)

1. + exchanger in human platelets. Differential effect of phorbol ester and vasopressin. J. Biol. Chem. 271: 16494-16499, 1996.
2. + exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites. J. Biol. Chem. 269: 13703-13709, 1994.
3. + antiport in type II alveolar epithelial cells. Am. J. Physiol. 261 (Cell Physiol. 30): C954-C963, 1991.
4. + antiport in cultured human cells. Modulation of the regulatory effect of intracellular protons on the antiporter activity. J. Biol. Chem. 261: 5460-5466, 1986.
5. Chan, P. C., V. Calabrese, and L. S. Thiel. Species differences in the effect of sodium and potassium ions on the ATPase of erythrocyte membranes. Biochim. Biophys. Acta 79: 424-431, 1964.
6. Colclasure, G. C., and J. C. Parker. Cytosolic protein concentration is the primary volume signal in dog red cells. J. Gen. Physiol. 98: 881-892, 1991.
7. Condrescu, M., J. P. Gardner, G. Chernaya, J. F. Aceto, C. Kroupis, and J. P. Reeves. ATP-dependent regulation of sodium-calcium exchange in Chinese hamster ovary cells transfected with the bovine cardiac sodium-calcium exchanger. J. Biol. Chem. 270: 9137-9146, 1995.
8. + exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain. Biochemistry 33: 10463-10469, 1994.
9. + antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties. Mol. Pharmacol. 44: 1041-1045, 1993.
10. + exchange. Nucleotide specificity and assessment of the role of phospholipids. J. Gen. Physiol. 109: 117-128, 1997.
11. DiPolo, R., G. Berberian, D. Delgado, H. Rojas, and L. Beauge. A novel 13 kDa cytoplasmic soluble protein is required for the nucleotide (MgATP) modulation of the Na/Ca exchange in squid nerve fibers. FEBS Lett. 401: 6-10, 1997.
12. Funder, J., J. C. Parker, and J. O. Wieth. Further evidence for coupling of sodium and proton movements in dog red blood cells. Biochim. Biophys. Acta 899: 311-312, 1987.
13. Golenhofen, N., R. B. Doctro, R. Bacallao, and L. J. Mandell. Actin and villin compartmentation during ATP depletion and recovery in renal cultured cells. Kidney Int. 48: 1837-1845, 1996.