Interaction between anesthetics and the sodium-hydrogen exchange inhibitor HOE 642 (cariporide) in ischemic and reperfused rat hearts

Anesthesiology

Volumn 87, Issue 6, 1997, Pages 1460-1469

  Mathur, Sanjiv ^b   Karmazyn, Morris ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b NONE

Author keywords

Anesthetics, volatile; Cardioprotection; Ischemia; Isoflurane; Reperfusion; Sevoflurane; Sodium hydrogen exchange; Sufentanil

Indexed keywords

ANESTHETIC AGENT; CARIPORIDE; ISOFLURANE; SEVOFLURANE; SUFENTANIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DRUG EFFICACY; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PROTECTION; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HIGH RISK POPULATION; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; REPERFUSION;

ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; DRUG INTERACTIONS; ETHERS; GUANIDINES; HEMODYNAMIC PROCESSES; ISOFLURANE; MALE; METHYL ETHERS; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-HYDROGEN ANTIPORTER; SUFENTANIL; SULFONES;

EID: 0031468294     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199712000-00025     Document Type: Article

References (34)

1. Fliegel L, Fröhlich O: The Na/H exchanger: An update on structure, regulation and cardiac physiology. Biochem J 1993; 296:273-85
2. Lazdunski M, Frélin C, Vigne P: The sodium/hydrogen exchange system in cardiac cells: Its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH. J Mol Cell Cardiol 1985; 17:1029-42
3. Karmazyn M, Moffat MP: Role of Na/H exchange in cardiac physiology and pathophysiology: Mediation of myocardial reperfusion injury by the pH paradox. Cardiovasc Res 1993; 27:915-24
4. Karmazyn M: Role of sodium-hydrogen exchange in mediating myocardial ischemic and reperfusion injury: mechanisms and therapeutic implications, The Na/H Exchange. Edited by L Fliegel. Austin, TX, Landes Bioscience Publishers, 1996
5. Karmazyn M: The sodium-hydrogen exchange system in the heart: Its role in ischemic and reperfusion injury and therapeutic implications. Can J Cardiol 1996; 12:1074-82
6. Pierce GN, Czubryt MP: The contribution of ionic imbalance to ischemia/reperfusion-induced injury. J Mol Cell Cardiol 1995; 27:53-63
7. Karmazyn M: Sodium-hydrogen exchange inhibition: A superior cardioprotective strategy. J Thorac Cardiovasc Surg 1996; 112:776-7
8. Freedman BM, Hamm DP, Everson CT, Wechsler AS, Christian CM II: Enflurane enhances postischemic functional recovery in the isolated rat heart. ANESTHESIOLOGY 1985; 62:29- 33
9. Warltier DC, Al-Wathiqui MH, Kampine JP, Schmeling WT: Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane. ANESTHESIOLOGY 1988; 69:552-65
10. Coetzee A, Brits W, Genade S, Lochner A: Halothane does have protective properties in the isolated ischemic rat heart. Anesth Analg 1991; 73:711-9
11. Buljubasic N, Marijic J, Stowe DF, Kampine JP, Bosnjak ZJ: Halothane reduces dysrhythmias and improves contractile function after global hypoperfusion in isolated hearts. Anesth Analg 1992; 74:384-94
12. Buljubasic N, Stowe DF, Marijic J, Roerig DL, Kampine JP, Bosnjak ZJ: Halothane reduces release of adenosine, inosine, and lactate with ischemia and reperfusion in isolated hearts. Anesth Analg 1993; 76:54-62
13. Coetzee A, Moolman J: Halothane and the reperfusion injury in the intact animal model. Anesth Analg 1993; 76:734-44
14. Lochner A, Harper IS, Salie R, Genade S, Coetzee AR: Halothane protects the isolated rat myocardium against excessive total intracellular calcium and structural damage during ischemia and reperfusion. Anesth Analg 1994; 79:226-33
15. Kanaya N, Fujita S: The effects of isoflurane on regional myocardial contractility and the metabolism in "stunned" myocardium in acutely instrumented dogs. Anesth Analg 1994; 79:447-54
16. Kanaya N, Kobayashi I, Nakayama M, Fujita S, Namiki A: ATP sparing effect of isoflurane during ischemia and reperfusion in the canine heart. Br J Anaesth 1995; 74:563-8
17. Oguchi T, Kashimoto S, Yamaguchi T, Nakamura T, Kumazawa T: Comparative effects of halothane, enflurane, isoflurane, and sevoflurane on function and metabolism in the ischaemic rat heart. Br J Anaesth 1995; 74:569-75
18. ATP) channels. ANESTHESIOLOGY 1996; 85:27A
19. Kersten JR, Lowe D, Hettrick DA, Pagel PS, Gross GJ, Warltier DC: Glyburide, a K-ATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium. Anesth Analg 1996; 83:27-33
20. ATP) channels. ANESTHESIOLOGY 1996; 85:794-807
21. Schultz JEL, Hsu AK, Gross GJ: Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart. Circ Res 1996; 78:1100-4
22. Chen YT, Lin CJ, Lee AY, Chen JS, Hwang DS: Stereospecific blocking effects of naloxone against hemodynamic compromise and ventricular dysfunction due to myocardial ischemia and reperfusion. Int J Cardiol 1995; 50:125-9
23. Boban M, Stowe DF, Buljubasic N, Kampine JP, Bosnjak ZJ: Direct comparative effects of isoflurane and desflurane in isolated guinea pig hearts. ANESTHESIOLOGY 1992; 76:775-80
24. Haworth RA, Goknur AB: Inhibition of sodium/calcium exchange and calcium channels of heart cells by volatile anesthetics. ANESTHESIOLOGY 1995; 82:1255-65
25. Bergmeyer HU: Methods in Enzymatic Analysis. New York, Academic Press, 1963
26. Scholz W, Albus U, Counillon L, Gogelein H, Lang H-J, Linz W, Weichert A, Schölkens BA: Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. Cardiovasc Res 1995; 29:260-8
27. Wheeler DM, Katz A, Rice T, Hansford RG: Volatile anesthetic effects on sarcoplasmic reticulum Ca content and sarcolemmal Ca flux in isolated rat cardiac cell suspensions. ANESTHESIOLOGY 1994; 80:372-82
28. 2+ mobilization in isolated cardiac myocytes. ANESTHESIOLOGY 1993; 79:73-82
29. Tavernier BM, Adnet PJ, Imbenotte M, Etchrivi TS, Reyford H, Haudecoeur G, Scherpereel P, Horber RM: Halothane and isoflurane decrease calcium sensitivity and maximal force in human skinned cardiac fibers. ANESTHESIOLOGY 1994; 80:625-33
30. Stowe DF, Sprung J, Turner LA, Kampine JP, Bosnjak ZJ: Differential effects of halothane and isoflurane on contractile force and calcium transients in cardiac purkinje fibers. ANESTHESIOLOGY 1994; 80:1360-8
31. Pagel PS, Kampine JP, Schmeling WT, Warltier DC: Reversal of volatile anesthetic-induced depression of myocardial contractility by extracellular calcium also enhances left ventricular diastolic function. ANESTHESIOLOGY 1993; 78:141-54
32. + channels in rabbit ventricular myocytes. Biochem Biophys Res Commun 1996; 229:852-6
33. Grover GJ: The role of ATP-sensitive potassium channels in myocardial ischemia: Pharmacology and implications for the future, Myocardial Ischemia: Mechanisms, Reperfusion, Protection. Edited by M Karmazyn. Basel, Birkhäuser Verlag, 1996, pp 313-24
34. Boutros A, Wang J, Capuano C: Isoflurane and halothane increase adenosine triphosphate preservation, but do not provide additive recovery of function after ischemia, in preconditioned rat hearts. ANESTHESIOLOGY 1997; 86:109-17