Alteration of intracellular Na+ during ischemia in diabetic rat hearts: The role of reduced activity in Na+/H+ exchange against stunning

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 3, 1998, Pages 509-517

  Imahashi, Kenichi ^a   Hashimoto, Katsuji ^a   Yamaguchi, Hitoshi ^a   Nishimura, Tsunehiko ^a   Kusuoka, Hideo ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

23Na MRS; Dy(PPP)27 ; Dy(TTHA)3 ; EIPA; Ischemia reperfusion; Streptozotocin; Na+ (i)

Indexed keywords

PROTON; SODIUM ION; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; SODIUM CELL LEVEL; SODIUM TRANSPORT; STUNNED HEART MUSCLE;

EID: 0032031520     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0615     Document Type: Article

References (28)

1. 87Rb NMR spectroscopic study. Magn Reson Med 34: 673-685.
2. HASHIMOTO K, NISHIMURA T, ISHIKAWA M, KOGA K, MORI T, MATSUDA S, HORI M, KUSUOKA H, 1997. Enhancement of glucose uptake in stunned myocardium: role of glucose transporter. Am J Physiol 272: H1122-H1130.
3. INGWALL JS, 1995. How high does intracellular sodium rise during acute myocardial ischaemia? A view from NMR spectroscopy. Cardiovasc Res 29: 279.
4. 31P nuclear magnetic resonance and mass spectroscopy study. In: Nuccitelli R and Deamer DW (eds). Intracellular pH: Its Measurement, Regulation and Utilization in Cellular Function. New York: Alan R Liss Inc., 537-565.
5. + exchange. Am J Physiol 255: H608-H615.
6. + exchange during ischemia and reperfusion of normal and diabetic rat hearts. Cardiovasc Res 24: 873-878.
7. KHANDOUDI N, BERNARD M, COZZONE P, FEUVRAY D, 1995. Mechanisms of intracellular pH regulation during post-ischemic reperfusion of diabetic rat hearts. Diabetes 44: 196-202.
8. + pump concentration in skeletal muscle, heart ventricular muscle, and peripheral nerves of rat. Diabetes 36: 842-848.
9. KUSAMA Y, HEARSE DJ, AVKIRAN M, 1992. Diabetes and susceptibility to reperfusion-induced arrhythmias. J Mol Cell Cardiol 24: 411-421.
10. 2+-activated force by inorganic phosphate. Circ Res 59: 270-282.
11. KUSUOKA H, MARBAN E, 1992. Cellular mechanisms of myocardial stunning. Annu Rev Physiol 54: 243-256.
12. KUSUOKA H, HURTADO MCC, MARBAN E, 1993. Role of sodium/calcium exchange in the mechanism of myocardial stunning: protective effect of reperfusion with high sodium solution. J Am Coll Cardiol 21: 240-248.
13. LAGADIC-GOSSMANN D, FEUVRAY D, 1991. Intracellular sodium activity in papillary muscle from diabetic rat hearts. Exp Physiol 76: 147-149.
14. LAGADIC-GOSSMANN D, CHESNAIS JM, FEUVRAY D, 1988. Intracellular pH regulation in papillary muscle cells from streptozotocin diabetic rats: an ion-sensitive microelectrode study. Pflügers Arch 412: 613-617.
15. 2+ handling in ventricular myocytes isolated from diabetic rats. Am J Physiol 270: H1529-H1537.
16. LAZDUNSKI M, FRELIN C, VIGNE P, 1985. The sodium/ hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH. J Mol Cell Cardiol 17: 1029-1042.
17. + exchange in diabetic rat isolated ventricular myocytes. Circ Res 80: 253-260.
18. 2+ transport in streptozotocin-induced diabetic cardiomyopathy in rats. Am J Physiol 253: E202-E207.
19. + exchange on intracellular sodium and pH in working and ischemic hearts. Magn Reson Med 32: 556-564.
20. +-ATPaSe isoforms in heart, skeletal muscle, and kidney of diabetic rats. Am J Physiol 265: E243-E251.
21. 2+ concentration and pH of diabetic rat myocytes during metabolic inhibition. J Mol Cell Cardiol 24: 435-446.
22. 39K nuclear magnetic resonance studies of perfused rat hearts. Discrimination of intra- and extracellular ions using a shift reagent. Biophys J 48: 159-173.
23. 23Na-NMR measurements of intracellular sodium in intact perfused ferret hearts during ischemia and reperfusion. Am J Physiol 259: H1767-H1773.
24. + exchange. Am J Physiol 265: H2017-H2026.
25. 2+ metabolism. Circ Res 62: 931-940.
26. 2+ exchange. Circ Res 65: 1045-1056.
27. 23Na NMR study. J Mol Cell Cardiol 23: 297-307.
28. WARLEY A, 1991. Changes in sodium concentration in cardiac myocytes from diabetic rats. Scanning-Microscopy 5: 239-244.