메뉴 건너뛰기




Volumn 101, Issue 6, 1998, Pages 1362-1372

Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnuclesomes

Author keywords

Anti DNA; Autoimmunity; Chromatin; Lupus; Nucleosomes

Indexed keywords

ANTINUCLEAR ANTIBODY; DNA; HISTONE; IMMUNOGLOBULIN G;

EID: 0032520923     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (256)

References (58)
  • 1
    • 0028858002 scopus 로고
    • Lupus: Key pathogenic mechanisms and contributing factors
    • Mohan, C., and S.K. Datta. 1995. Lupus: key pathogenic mechanisms and contributing factors. Clin. Immunol. Immunopathol. 77:209-220.
    • (1995) Clin. Immunol. Immunopathol. , vol.77 , pp. 209-220
    • Mohan, C.1    Datta, S.K.2
  • 2
    • 0028869486 scopus 로고
    • The basis of autoimmunity. I. Mechanisms of aberrant self-recognition
    • Theofilopoulos, A.N. 1995. The basis of autoimmunity. I. Mechanisms of aberrant self-recognition. Immunol. Today. 16:90-98.
    • (1995) Immunol. Today , vol.16 , pp. 90-98
    • Theofilopoulos, A.N.1
  • 4
    • 0015089035 scopus 로고
    • Reactions of systemic lupus erythematosus sera with histone tractions and histone-DNA complexes
    • Stollar, B.D. 1971. Reactions of systemic lupus erythematosus sera with histone tractions and histone-DNA complexes. Arthritis Rheum. 14:485-492.
    • (1971) Arthritis Rheum. , vol.14 , pp. 485-492
    • Stollar, B.D.1
  • 5
    • 0028284788 scopus 로고
    • The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus
    • Burlingame, R.W., M.L. Boey, G. Starkebaum, and R.L. Rubin. 1994. The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus. J. Clin. Invest. 94:184-192.
    • (1994) J. Clin. Invest. , vol.94 , pp. 184-192
    • Burlingame, R.W.1    Boey, M.L.2    Starkebaum, G.3    Rubin, R.L.4
  • 6
    • 0027245507 scopus 로고
    • Genesis and evolution of antichromatin autoanlibodies in murine lupus implicates T-dependent immunization with self antigen
    • Burlingame, R.W., R.L. Rubin, R.S. Balderas, and A.N. Theofilopoulos. 1993. Genesis and evolution of antichromatin autoanlibodies in murine lupus implicates T-dependent immunization with self antigen. J. Clin. Invest. 91:1687-1696.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1687-1696
    • Burlingame, R.W.1    Rubin, R.L.2    Balderas, R.S.3    Theofilopoulos, A.N.4
  • 7
    • 0027477318 scopus 로고
    • Nuclcosome: A major immunogen for pathogenic autoamibody-inducing T cells of lupus
    • Mohan, C., S. Adams, V. Stanik, and S.K. Datta. 1993. Nuclcosome: a major immunogen for pathogenic autoamibody-inducing T cells of lupus. J. Exp. Med. 177:1367-1381.
    • (1993) J. Exp. Med. , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 8
    • 0029953857 scopus 로고    scopus 로고
    • Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus
    • Kaliyaperumal, A., C. Mohan, W. Wu, and S.K. Datta. 1996. Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus. J. Exp. Med. 183:2459-2469.
    • (1996) J. Exp. Med. , vol.183 , pp. 2459-2469
    • Kaliyaperumal, A.1    Mohan, C.2    Wu, W.3    Datta, S.K.4
  • 9
    • 0028798616 scopus 로고
    • Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
    • Desai-Mehta, A., C. Mao, S. Rajagopalan, T. Robinson, and S.K. Datta. 1995. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J. Clin. Invest. 95:531-541.
    • (1995) J. Clin. Invest. , vol.95 , pp. 531-541
    • Desai-Mehta, A.1    Mao, C.2    Rajagopalan, S.3    Robinson, T.4    Datta, S.K.5
  • 10
    • 10144242672 scopus 로고    scopus 로고
    • dsDNA-, nucleohistone- and DNASE 1-reactive T lymphocytes in patients affected by systemic lupus erythematosus: Correlation with clinical disease activity
    • Filaci, G., I. Grasso, P. Contini, M.A. Imro, L. Lanza, M. Scudeletti, E. Rossi, F. Puppo, E. Damasio, and F. Indiveri. 1996. dsDNA-, nucleohistone- and DNASE 1-reactive T lymphocytes in patients affected by systemic lupus erythematosus: correlation with clinical disease activity. Clin. Exp. Rheumatol. 14:543-550.
    • (1996) Clin. Exp. Rheumatol. , vol.14 , pp. 543-550
    • Filaci, G.1    Grasso, I.2    Contini, P.3    Imro, M.A.4    Lanza, L.5    Scudeletti, M.6    Rossi, E.7    Puppo, F.8    Damasio, E.9    Indiveri, F.10
  • 11
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse. T.J., and J.A. Todd. 1996. Genetic analysis of autoimmune disease. Cell. 85:311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 14
    • 0030140063 scopus 로고    scopus 로고
    • Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain
    • Morel, L., Y. Yu, K.R. Blenman, R.A. Caldwell, and E.K. Wakeland. 1996. Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain. Mamm. Genome. 7:335-339.
    • (1996) Mamm. Genome. , vol.7 , pp. 335-339
    • Morel, L.1    Yu, Y.2    Blenman, K.R.3    Caldwell, R.A.4    Wakeland, E.K.5
  • 15
    • 0031570375 scopus 로고    scopus 로고
    • Functional dissection of SLE pathogenesis using congenic mouse strains
    • Morel, L., C. Mohan, Y. Yu, B. Croker, X. Tian, A. Deng, and E.K. Wakeland. 1997. Functional dissection of SLE pathogenesis using congenic mouse strains. J Immunol. 158:6019-6028.
    • (1997) J Immunol. , vol.158 , pp. 6019-6028
    • Morel, L.1    Mohan, C.2    Yu, Y.3    Croker, B.4    Tian, X.5    Deng, A.6    Wakeland, E.K.7
  • 16
    • 0024692560 scopus 로고
    • Relation of antinuclear fluorescence patterns and titres to autoantibody prevalence
    • Mohan. T.C., M. Nadarajah, and E.H. Sng. 1989. Relation of antinuclear fluorescence patterns and titres to autoantibody prevalence. Ann. Acad. Med. Singapore. 18:339-344.
    • (1989) Ann. Acad. Med. Singapore , vol.18 , pp. 339-344
    • Mohan, T.C.1    Nadarajah, M.2    Sng, E.H.3
  • 17
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan, C., Y. Shi, J.D. Laman, and S.K. Datta. 1995. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154:1470-1480.
    • (1995) J. Immunol. , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 18
    • 0025011972 scopus 로고
    • Subnucleosome structures as substrates in enzyme-linked immunosorbent assays
    • Burlingame, R.W., and R.L. Rubin. 1990. Subnucleosome structures as substrates in enzyme-linked immunosorbent assays. J. Immunol. Methods. 134: 187-199.
    • (1990) J. Immunol. Methods , vol.134 , pp. 187-199
    • Burlingame, R.W.1    Rubin, R.L.2
  • 19
    • 0026564699 scopus 로고
    • Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-)+/+ mouse. Oligoclonality of the antibody response and recognition of a determinant composed of histones H2A, H2B, and DNA
    • Losman, M.J., T.M. Fasy, K.E. Novick, and M. Monestier. 1992. Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-)+/+ mouse. Oligoclonality of the antibody response and recognition of a determinant composed of histones H2A, H2B, and DNA. J. Immunol. 148:1561-1569.
    • (1992) J. Immunol. , vol.148 , pp. 1561-1569
    • Losman, M.J.1    Fasy, T.M.2    Novick, K.E.3    Monestier, M.4
  • 20
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyle apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., G. Migliorati, M.C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyle apoptosis by propidium iodide staining and flow cytometry, J. Immunol Methods. 139:271-279.
    • (1991) J. Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 21
    • 0028073897 scopus 로고
    • Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria
    • Amoura, Z., H. Chabre, S. Koutouzov, C. Lotion, A. Cabrespines, J.F. Bach, and L. Jacob. 1994. Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria. Arthritis Rheum. 37:1684-1688.
    • (1994) Arthritis Rheum. , vol.37 , pp. 1684-1688
    • Amoura, Z.1    Chabre, H.2    Koutouzov, S.3    Lotion, C.4    Cabrespines, A.5    Bach, J.F.6    Jacob, L.7
  • 22
    • 0027230775 scopus 로고
    • Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization
    • Rudofsky, U.H., B.D. Evans. S.L. Balahan, V.D. Mottironi, and A.E. Gabrielsen. 1993. Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization. Lab. Invest. 68:419-426.
    • (1993) Lab. Invest. , vol.68 , pp. 419-426
    • Rudofsky, U.H.1    Evans, B.D.2    Balahan, S.L.3    Mottironi, V.D.4    Gabrielsen, A.E.5
  • 23
    • 84873798056 scopus 로고
    • Presentation of two bone marrow elements: The "tart" cell and the "L.E." cell
    • Hargraves, M.M., H. Richmond, and R. Morton. 1948. Presentation of two bone marrow elements: the "tart" cell and the "L.E." cell. Proc. Mayo Clin. 23:25-28.
    • (1948) Proc. Mayo Clin. , vol.23 , pp. 25-28
    • Hargraves, M.M.1    Richmond, H.2    Morton, R.3
  • 24
    • 0000137417 scopus 로고
    • Affinity between the lupus erythematosus serum factor and cell nuclei and nucleoprotein
    • Holman, R.H., and H.G. Kunkel. 1957. Affinity between the lupus erythematosus serum factor and cell nuclei and nucleoprotein. Science. 126: 162-163.
    • (1957) Science , vol.126 , pp. 162-163
    • Holman, R.H.1    Kunkel, H.G.2
  • 25
    • 0000597563 scopus 로고
    • The reaction of the lupus erythematosus (L.E.) cell factor with deoxyribonucleoprotein of the cell nucleus
    • Holman, H., and H.R. Deicher. 1959. The reaction of the lupus erythematosus (L.E.) cell factor with deoxyribonucleoprotein of the cell nucleus. J. Clin. Invest. 38:2059-2072.
    • (1959) J. Clin. Invest. , vol.38 , pp. 2059-2072
    • Holman, H.1    Deicher, H.R.2
  • 26
    • 0018870012 scopus 로고
    • Evidence for a subset of rheumatoid factors that cross-react with DNA-histone and have a distinct cross-idiotype
    • Agnello, V., A. Arbeiter, G. Ibanez de Kasep, R. Powell, E.M. Tan, and F. Joslin. 1980. Evidence for a subset of rheumatoid factors that cross-react with DNA-histone and have a distinct cross-idiotype. J. Exp. Med. 151:1514-1527.
    • (1980) J. Exp. Med. , vol.151 , pp. 1514-1527
    • Agnello, V.1    Arbeiter, A.2    Ibanez De Kasep, G.3    Powell, R.4    Tan, E.M.5    Joslin, F.6
  • 27
    • 0019200392 scopus 로고
    • Human autoantibodies that react with both cell nuclei and plasma membranes display specificity for the octamer of histones H2A, H2B, H3, and H4 in high salt
    • Rekvig, O.P., and K. Hannestad. 1980. Human autoantibodies that react with both cell nuclei and plasma membranes display specificity for the octamer of histones H2A, H2B, H3, and H4 in high salt. J. Exp. Med. 152:1720-1733.
    • (1980) J. Exp. Med. , vol.152 , pp. 1720-1733
    • Rekvig, O.P.1    Hannestad, K.2
  • 28
    • 0028803299 scopus 로고
    • Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosus
    • Chabre, H., Z. Amoura, J. Piette, P. Godeau, J. Bach, and S. Koutouzov. 1995. Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosus. Arthritis Rheum. 38:1485-1491.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1485-1491
    • Chabre, H.1    Amoura, Z.2    Piette, J.3    Godeau, P.4    Bach, J.5    Koutouzov, S.6
  • 29
    • 0028123813 scopus 로고
    • Systemic lupus erythematosus. Antibodies to DNA, DNA-binding proteins, and histones
    • Reeves, W.H., M. Satoh, J. Wang. C.H. Chou, and A.K. Ajmani. 1994. Systemic lupus erythematosus. Antibodies to DNA, DNA-binding proteins, and histones. Rheum. Dis. Clin. N. Am. 20:1-28.
    • (1994) Rheum. Dis. Clin. N. Am. , vol.20 , pp. 1-28
    • Reeves, W.H.1    Satoh, M.2    Wang, J.3    Chou, C.H.4    Ajmani, A.K.5
  • 31
    • 0020494579 scopus 로고
    • Subnucleosomes and their relationships to the arrangement of histone binding sites along nucleosome deoxyribonucleic acid
    • Nelson. D.A., A.J. Mencke, S.A. Chambers, D.K. Oosterhof, and R.L. Rill. 1982. Subnucleosomes and their relationships to the arrangement of histone binding sites along nucleosome deoxyribonucleic acid. Biochemistry. 21: 4350.
    • (1982) Biochemistry , vol.21 , pp. 4350
    • Nelson, D.A.1    Mencke, A.J.2    Chambers, S.A.3    Oosterhof, D.K.4    Rill, R.L.5
  • 32
    • 0023660709 scopus 로고
    • Spectroscopic studies on histone-DNA interactions. I. The interaction of histone (H2A, H2B) dimer with DNA: DNA sequence dependence
    • Oohara. I., and A. Wada. 1987. Spectroscopic studies on histone-DNA interactions. I. The interaction of histone (H2A, H2B) dimer with DNA: DNA sequence dependence. J. Mol. Biol. 196:389-397.
    • (1987) J. Mol. Biol. , vol.196 , pp. 389-397
    • Oohara, I.1    Wada, A.2
  • 33
    • 0017762802 scopus 로고
    • Reconstitution of chromatin core particles
    • Tatchell, K., and K.E. Van Holde. 1977. Reconstitution of chromatin core particles. Biochemistry. 16:5295-5303.
    • (1977) Biochemistry , vol.16 , pp. 5295-5303
    • Tatchell, K.1    Van Holde, K.E.2
  • 34
    • 0019877676 scopus 로고
    • Study of conformational states and reversibility of histone complexes
    • Beaudette, N.V., A.W. Fulmer, H. Okabayashi, and G.D. Fasman. 1981. Study of conformational states and reversibility of histone complexes. Biochemistry. 20:6526.
    • (1981) Biochemistry , vol.20 , pp. 6526
    • Beaudette, N.V.1    Fulmer, A.W.2    Okabayashi, H.3    Fasman, G.D.4
  • 35
    • 0346879117 scopus 로고
    • Correlation of antinuclear antibodies and nuclear staining pattern
    • Lachman, P.J., and H.G. Kunkel. 1961. Correlation of antinuclear antibodies and nuclear staining pattern. Lancet. 2:436.
    • (1961) Lancet , vol.2 , pp. 436
    • Lachman, P.J.1    Kunkel, H.G.2
  • 36
    • 0014146804 scopus 로고
    • Relationship of nuclear staining patterns with precipitating antibodies in systemic lupus erythematosus
    • Tan, E.M. 1967. Relationship of nuclear staining patterns with precipitating antibodies in systemic lupus erythematosus. J. Lab. Clin. Med. 70:800-812.
    • (1967) J. Lab. Clin. Med. , vol.70 , pp. 800-812
    • Tan, E.M.1
  • 37
    • 0025837183 scopus 로고
    • The nucleosomal core histone octameral 3.1 a resolution: A tripartite protein assembly and a left-handed superhelix
    • Arents, G., R.W. Burlingame, B.C. Wang, W.E. Love, and E.N. Moudrianakis. 1991. The nucleosomal core histone octameral 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc. Natl. Acad. Sci. USA. 88:10148.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10148
    • Arents, G.1    Burlingame, R.W.2    Wang, B.C.3    Love, W.E.4    Moudrianakis, E.N.5
  • 38
    • 0029899083 scopus 로고    scopus 로고
    • Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies
    • Lefkowith, J.B., and G.S. Gilkeson. 1996. Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies. Arthritis Rheum. 39: 894-903.
    • (1996) Arthritis Rheum. , vol.39 , pp. 894-903
    • Lefkowith, J.B.1    Gilkeson, G.S.2
  • 39
    • 0028952442 scopus 로고
    • Glomerular binding activity in MRL 1pr serum consists of antibodies that bind to a DNA/ histone/type IV collagen complex
    • Bernstein, K.A., R.D. Valerio, and J.B. Lefkowith. 1995. Glomerular binding activity in MRL 1pr serum consists of antibodies that bind to a DNA/ histone/type IV collagen complex. J. Immunol. 154:2424-2433.
    • (1995) J. Immunol. , vol.154 , pp. 2424-2433
    • Bernstein, K.A.1    Valerio, R.D.2    Lefkowith, J.B.3
  • 41
    • 0026742304 scopus 로고
    • Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex
    • Rubin, R.L., S.A. Bell, and R.W. Burlingame. 1992. Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex. J. Clin. Invest. 90:165-173.
    • (1992) J. Clin. Invest. , vol.90 , pp. 165-173
    • Rubin, R.L.1    Bell, S.A.2    Burlingame, R.W.3
  • 43
    • 0023944349 scopus 로고
    • Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus
    • Totoritis, M.C., E.M. Tan, E.M. McNally, and R.L. Rubin. 1988. Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus. N. Engl. J. Med. 318:1431.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1431
    • Totoritis, M.C.1    Tan, E.M.2    McNally, E.M.3    Rubin, R.L.4
  • 44
    • 0024564213 scopus 로고
    • Cellular interactions for the in vitro production of anti-chromatin autoantibodies in MRL/Mp-lpr/lpr mice
    • Fisher, C.L., E.W. Shores, R.A. Eisenberg, and P.L. Cohen. 1989. Cellular interactions for the in vitro production of anti-chromatin autoantibodies in MRL/Mp-lpr/lpr mice. Clin. Immunol. hmmunopathol. 50:231-240.
    • (1989) Clin. Immunol. Hmmunopathol. , vol.50 , pp. 231-240
    • Fisher, C.L.1    Shores, E.W.2    Eisenberg, R.A.3    Cohen, P.L.4
  • 45
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis: Sle2 on murine chromosome 4 leads to B-cell hyperactivity
    • Mohan, C., L. Morel, B. Croker, P. Yang, and F.K. Wakeland. 1997. Genetic dissection of SLE pathogenesis: Sle2 on murine chromosome 4 leads to B-cell hyperactivity. J. Immunol. 159:454-165.
    • (1997) J. Immunol. , vol.159 , pp. 454-1165
    • Mohan, C.1    Morel, L.2    Croker, B.3    Yang, P.4    Wakeland, F.K.5
  • 46
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen, W., J. Niebur, and R. Kadera. 1994. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol. 152:3685-3692.
    • (1994) J. Immunol. , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 47
    • 0026737347 scopus 로고
    • Accelerated programmed cell death of MRL-lpr/lpr T lymphocytes
    • Van Houten. N., and R.C. Budd. 1992. Accelerated programmed cell death of MRL-lpr/lpr T lymphocytes. J. Immunol. 149:2513-2517.
    • (1992) J. Immunol. , vol.149 , pp. 2513-2517
    • Van Houten, N.1    Budd, R.C.2
  • 48
    • 0028889990 scopus 로고
    • Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice
    • Reap, E.A., D. Leslie, M. Abrahams, R.A. Eisenberg, and P.L. Cohen. 1995. Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. J. Immunol. 154:936-943.
    • (1995) J. Immunol. , vol.154 , pp. 936-943
    • Reap, E.A.1    Leslie, D.2    Abrahams, M.3    Eisenberg, R.A.4    Cohen, P.L.5
  • 49
    • 0029977019 scopus 로고    scopus 로고
    • Resting B cells from New Zealand black mice demonstrate a defect in apoptosis induction following surface IgM ligation
    • Kozono, Y., B. Kotzin, and V.M. Holers. 1996. Resting B cells from New Zealand black mice demonstrate a defect in apoptosis induction following surface IgM ligation. J. Immunol. 156:4498-1503.
    • (1996) J. Immunol. , vol.156 , pp. 4498-11503
    • Kozono, Y.1    Kotzin, B.2    Holers, V.M.3
  • 50
    • 0014259755 scopus 로고
    • Pathogenesis of the glomerulonephritis of NZB/W mice
    • Lambert, P.H. and F.J. Dixon. 1968. Pathogenesis of the glomerulonephritis of NZB/W mice. J. Exp. Mad. 127:507-522.
    • (1968) J. Exp. Mad. , vol.127 , pp. 507-522
    • Lambert, P.H.1    Dixon, F.J.2
  • 51
    • 0019201556 scopus 로고
    • Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus
    • Raplis, L., and H.A. Menard. 1980. Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus. J. Clin. Invest. 66:1391-1399.
    • (1980) J. Clin. Invest. , vol.66 , pp. 1391-1399
    • Raplis, L.1    Menard, H.A.2
  • 52
    • 0021243168 scopus 로고
    • Partial purification and characterization of plasma DNA and its relation to disease activity in systemic lupus erythematosus
    • McCoubrey Hoyer, A., T.B. Okarma, and H.R. Holman. 1984. Partial purification and characterization of plasma DNA and its relation to disease activity in systemic lupus erythematosus. Am. J. Med. 77:23-34.
    • (1984) Am. J. Med. , vol.77 , pp. 23-34
    • McCoubrey Hoyer, A.1    Okarma, T.B.2    Holman, H.R.3
  • 53
    • 0021364682 scopus 로고
    • Circulating DNA in systemic lupus erythematosus. Isolation and characterization
    • Steinman, C.R. 1984. Circulating DNA in systemic lupus erythematosus. Isolation and characterization. J. Clin. Invest. 73:832-841.
    • (1984) J. Clin. Invest. , vol.73 , pp. 832-841
    • Steinman, C.R.1
  • 54
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptolic keratinocytes
    • Casciola Rosen, L.A., G. Anhalt, and A. Rosen. 1994. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptolic keratinocytes. J Exp. Med. 179:1317-1330.
    • (1994) J Exp. Med. , vol.179 , pp. 1317-1330
    • Casciola Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 55
    • 0025729604 scopus 로고
    • An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunily
    • Sobel, E.S., T. Katagiri, K. Katagiri, S.C. Morris, P.L. Cohen, and R.A. Eisenberg. 1991. An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunily. J. Exp. Med. 173:1441-1449.
    • (1991) J. Exp. Med. , vol.173 , pp. 1441-1449
    • Sobel, E.S.1    Katagiri, T.2    Katagiri, K.3    Morris, S.C.4    Cohen, P.L.5    Eisenberg, R.A.6
  • 56
    • 0028931042 scopus 로고
    • Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus
    • Roark, J.H., C.L. Kuntz, K. A. Nguyen, A.J. Caton, and J. Erikson. 1995. Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J. Exp. Med 181:1157-1167.
    • (1995) J. Exp. Med , vol.181 , pp. 1157-1167
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.A.3    Caton, A.J.4    Erikson, J.5
  • 57
    • 0029838992 scopus 로고    scopus 로고
    • Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB X NZW)F1 mice
    • Reininger, L., T.H. Winkler, C.P. Kalberer, M. Jourdan, F. Melchers, and A.G. Rolink. 1996. Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB X NZW)F1 mice. J. Exp. Med. 184:853-861.
    • (1996) J. Exp. Med. , vol.184 , pp. 853-861
    • Reininger, L.1    Winkler, T.H.2    Kalberer, C.P.3    Jourdan, M.4    Melchers, F.5    Rolink, A.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.