Activation of Human Eosinophils by IL-13: Induction of CD69 Surface Antigen, Its Relationship to Messenger RNA Expression, and Promotion of Cellular Viability

Journal of Immunology

Volumn 157, Issue 4, 1996, Pages 1678-1683

  Luttmann, Werner ^a   Knoechel, Birgit ^a   Foerster, Martin ^a   Matthys, Heinrich ^a   Virchow Jr , Johann Christian ^a   Kroegel, Claus ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b University Clinics   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; INTERLEUKIN 13; LEUKOCYTE ANTIGEN; MESSENGER RNA; SAPONIN; T LYMPHOCYTE ANTIGEN;

ARTICLE; BIOSYNTHESIS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; EOSINOPHIL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BASE SEQUENCE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-13; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SAPONINS;

EID: 0030586671     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Walker, C., J. C. Virchow, Jr., P. L. Bruijnzeel, and K. Blaser. 1991. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J. Immunol. 140:1829.
2. Hamid, Q., M. Azzawi, S. Ying, R. Moqbel, A. J. Wardlaw, C. J. Corrigan, B. Bradley, S. R. Durham, J. V. Collins, and P. K. Jeffery. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87:1541.
3. Corrigan, C. J., Q. Hamid, J. North, J. Barkans, R. Moqbel, S. Durham, V. Gemou-Engesaeth, and A. B. Kay. 1995. Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy. Am. J. Respir. Cell Mol. Biol. 12:567.
4. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and A. B. Kay. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298.
5. Rothenberg, M. E., W. F. Owen, Jr., D. S. Silberstein, J. Woods, R. J. Soberman, K. F. Austen, and R. L. Stevens. 1988. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J. Clin. Invest. 81:1986.
6. Lopez, A. F., D. J. Williamson, J. R. Gamble, C. G. Begley, J. M. Harlan, S. J. Klebanoff, A. Waltersdorph, G. Wong, S. C. Clark, and M. A. Vadas. 1986. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J. Clin. Invest. 78:1220.
7. Yamaguchi, Y., Y. Hayashi, Y. Sugama, Y. Miura, T. Kasahara, S. Kitamura, M. Torisu, S. Mita, A. Tominaga, and K. Takatsu. 1988. Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival: IL-5 as an eosinophil chemotactic factor. J. Exp. Med. 167:1737.
8. Clutterbuck, E. J., E. M. Hirst, and C. J. Sanderson. 1989. Human inlerleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF. Blood 73:1504.
9. Kapp, A., and G. Zeck-Kapp. 1991. Interleukin-5-induced granulocyte activation in atopic patients. Br. J. Dermatol. 125:108.
10. Tai, P. C., L. Sun, and C. J. Spry. 1991. Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro. Clin. Exp. Immunol. 85:312.
11. Sanderson, C. J. 1992. Interleukin-5, eosinophils, and disease. Blood 79:3101.
12. Coyle, A. J., G. Le Gros, C. Bertrand, S. Tsuyuki, C. H. Heusser, M. Kopf, and G. P. Anderson. 1995. Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am. J. Respir. Cell Mol. Biol. 13:54.
13. Schleimer, R. P., S. A. Sterbinsky, J. Kaiser, C. A. Bickel, D. A. Klunk, K. Tomioka, W. Newman, F. W. Luscinskas, M. A. Gimbrone, Jr., and B. W. McIntyre. 1992. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: association with expression of VCAM-1. J. Immunol. 148:1086.
14. Pene, J., F. Rousset, F. Briere, I. Chretien, X. Paliard, J. Banchereau, H. Spits, and J. E. de Vries. 1988. IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. J. Immunol. 141:1218.
15. Bergstedt-Lindqvist, S., H. B. Moon, U. Persson, G. Moller, C. Heusser, and E. Severinson. 1988. Interleukin 4 instructs uncommitted B lymphocytes to switch to IgG1 and IgE. Eur. J. Immunol. 18:1073.
16. Pene, J., I. Chretien, F. Rousset, F. Briere, J. Y. Bonnefoy, and J. E. de Vries. 1989. Modulation of IL-4-induced human IgE production in vitro by IFN-gamma and IL-5: the role of soluble CD23 (s-CD23). J. Cell Biochem. 39:253.
17. McKenzie, A. N., X. Li, D. A. Largaespada, A. Sato, A. Kaneda, S. M. Zurawski, E. L. Doyle, A. Milatovich, U. Francke, N. G. Copeland, N. A. Jenkis, and G. Zurawski. 1993. Structural comparison and chromosomal localization of the human and mouse IL-13 genes. J. Immunol. 150:5436.
18. Minty, A., P. Chalon, J. M. Derocq, X. Dumont, J. C. Guillemot, M. Kaghad, C. Labit, P. Leplatois, P. Liauzun, B. Miloux, C. Minty, P. Casellas, G. Loison, et al. 1993. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362:248.
19. Punnonen, J., G. Aversa, B. G. Cocks, A. N. McKenzie, S. Menon, G. Zurawski, R. de Waal Malefyt, and J. E. de Vries. 1993. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. USA 90:3730.
20. Muzio, M., F. Re, M. Sironi, N. Polentarutti, A. Minty, D. Caput, P. Ferrara, A. Mantovani, and F. Colotta. 1994. Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells. Blood 83:1738.
21. de Waal Malefyt, R., C. G. Figdor, R. Huijbens, S. Mohan-Peterson, B. Bennett, J. Culpepper, W. Dang, G. Zurawski, and J. E. de Vries. 1993. Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes: comparison with IL-4 and modulation by IFN-γ or IL-10. J. Immunol. 151:6370.
22. Nilsson, G., and K. Nilsson. 1995. Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells: comparison with IL-4. Eur. J. Immunol. 25:870.
23. Herbert, J. M., P. Savi, M. C. Laplace, A. Lale, F. Dol, A. Dumas, C. Labit, and A. Minty. 1993. IL-4 and IL-13 exhibit comparable abilities to reduce pyrogen-induced expression of procoagulant activity in endothelial cells and monocytes. FEBS Lett. 328:268.
24. Sironi, M., F. L. Sciacca, C. Matteucci, M. Conni, A. Vecchi, S. Bernasconi, A. Minty, D. Caput, P. Ferrara, and F. Colotta. 1994. Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood 84:1913.
25. Bochner, B. S., D. A. Klunk, S. A. Sterbinsky, R. L. Coffman, and R. P. Schleimer. 1995. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J. Immunol. 154:799.
26. Nakajima, H., H. Sano, T. Nishimura, S. Yoshida, and I. Iwamoto. 1994. Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue. J. Exp. Med. 179:1145.
27. Hartnell, A., D. S. Robinson, A. B. Kay, and A. J. Wardlaw. 1993. CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 80:281.
28. Nishikawa, K., T. Morii, H. Ako, K. Hamada, S. Saito, and N. Narita. 1992. In vivo expression of CD69 on lung eosinophils in eosinophilic pneumonia: CD69 as a possible activation marker for eosinophils. J. Allergy Clin. Immunol. 90:169.
29. Hansel, T. T., I. J. De Vries, T. Iff, S. Rihs, M. Wandzilak, S. Betz, K. Blaser, and C. Walker. 1991. An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J. Immunol. Methods 145:105.
30. Jung, L. K., B. F. Haynes, S. Nakamura, S. Pahwa, and S. M. Fu. 1990. Expression of early activation antigen (CD69) during human thymic development. Clin. Exp. Immunol. 81:466.
31. Kroegel, C., J. C. Virchow, Jr., W. Luttmann, C. Walker, and J. A. Warner. 1994. Pulmonary immune cells in health and disease: the eosinophil leucocyte (part I). Eur. Respir. J. 7:519.
32. Sedgwick, J. B., W. J. Calhoun, G. J. Gleich, H. Kita, J. S. Abrams, L. B. Schwartz, B. Volovitz, M. Ben-Yaakov, and W. W. Busse. 1991. Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge: characterization of eosinophil and mast cell mediators. Am. Rev. Respir. Dis. 144:1274.
33. Kato, M., M. C. Liu, B. A. Stealey, B. Friedman, L. M. Lichtenstein, S. Permutt, and R. P. Schleimer. 1992. Production of granulocyte/macrophage colony-stimulating factor in human airways during allergen-induced late-phase reactions in atopic subjects. Lymphokine Cytokine Res. 11:287.
34. Virchow, J. C., Jr., C. Walker, D. Hafner, C. Kortsik, P. Werner, H. Matthys, and C. Kroegel. 1995. T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma. Am. J. Respir. Crit. Care Med. 151:960.
35. Aversa, G., J. Punnonen, B. G. Cocks, R. de Waal Malefyt, F. Vega, Jr., S. M. Zurawski, G. Zurawski, and J. E. de Vries. 1993. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-I3 receptors. J. Exp. Med. 178:2213.
36. Ziegler, S. F., F. Ramsdell, and M. R. Alderson. 1994. The activation antigen CD69. Stem. Cells 12:456.
37. Bjorndahl, J. M., S. Nakamura, T. Hara, L. K. Jung, and S. M. Fu. 1988. The 28-kDa/32-kDa activation antigen EA 1: further characterization and signal requirements for its expression. J. Immunol. 141:4094.
38. Cebrian, M., J. Miguel Redondo, A. Lopez-Rivas, G. Rodriguez-Tarduchy, M. O. De Landazuri, and F. Sanchez-Madrid. 1989. Expression and function of AIM, an activation inducer molecule of human lymphocytes, is dependent on the activation of protein kinase C. Eur. J. Immunol. 19:809.
39. Hamann, J., H. Fiebig, and M. Strauss. 1993. Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain. J. Immunol. 150:4920.
40. ++] and stimulation of protein kinase C. J. Immunol. 142:1854.
41. Cebrian, M., E. Yague, M. Rincon, M. Lopez-Botet, M. O. de Landazuri, and F. Sanchez-Madrid. 1988. Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes. J. Exp. Med. 168:1621.
42. Nakamura, S., S. S. Sung, J. M. Bjorndahl, and S. M. Fu. 1989. Human T cell activation. IV. T cell activation and proliferation via the early activation antigen EA 1. J. Exp. Med. 169:677.
43. Santis, A. G., M. R. Campanero, J. L. Alonso, A. Tugores, M. A. Alonso, E. Yague, J. P. Pivel, and F. Sanchez-Madrid. 1992. Tumor necrosis factor-alpha production induced in T lymphocytes through the AIM/CD69 activation pathway. Eur. J. Immunol. 22:1253.
44. Sanchez-Mateos, P., M. Cebrian, A. Acevedo, M. Lopez-Botet, M. O. De Landazur, and F. Sanchez-Madrid. 1989. Expression of a gp33/27,000 MW activation inducer molecule (AIM) on human lymphoid tissues: induction of cell proliferation on thymocytes and B lymphocytes by anti-AIM antibodies. Immunology 68:72.
45. Testi, R., J. H. Phillips, and L. L. Lanier. 1989. T cell activation via Leu-23 (CD69). J. Immunol. 143:1123.
46. Yokoyama, W. M., F. Koning, P. J. Kehn, G. M. Pereira, G. Stingl, J. E. Coligan, and E. M. Shevach. 1988. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J. Immunol. 141:369.
47. Vancheri, C., J. Gauldie, J. Bienenstock, G. Cox. R. Scicchitano, A. Stanisz, and M. Jordana. 1989. Human lung fibroblast-derived granulocyte-macrophage colony stimulating factor (GM-CSF) mediates eosinophil survival in vitro. Am. J. Respir. Cell Mol Biol. 1:289.
48. Elices, M. J., L. Osborn, Y. Takada, C. Crouse, S. Luhowskyj, M. E. Hemler, and R. R. Lobb. 1990. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60:577.
49. Thornhill, M. H., S. M. Wellicome, D. L. Mahiouz, J. S. Lanchbury, U. Kyan-Aung, and D. O. Haskard. 1991. Tumor necrosis factor combines with IL-4 or IFN-gatnma to selectively enhance endothelial cell adhesiveness for T cells: the contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms. J. Immunol. 146:592.