-
2
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
3
-
-
0025840349
-
Transcriptional regulation of cytokine genes in nontransformed T cells
-
Brorson, K. A., B. Beverly, S.-M. Kang, M. Lenardo, and R. H. Schwartz. 1993. Transcriptional regulation of cytokine genes in nontransformed T cells. J. Immunol. 147:3601.
-
(1993)
J. Immunol.
, vol.147
, pp. 3601
-
-
Brorson, K.A.1
Beverly, B.2
Kang, S.-M.3
Lenardo, M.4
Schwartz, R.H.5
-
4
-
-
0027788043
-
The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producmg cells
-
Kamogawa, Y., L. A. Minasi, S. R. Carding, K. Bottomly, and R. A. Flavell. 1993. The relationship of IL-4-and IFN gamma-producing T cells studied by lineage ablation of IL-4-producmg cells. Cell 75:985.
-
(1993)
Cell
, vol.75
, pp. 985
-
-
Kamogawa, Y.1
Minasi, L.A.2
Carding, S.R.3
Bottomly, K.4
Flavell, R.A.5
-
5
-
-
0028346887
-
Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells
-
Schmitz, J., A. Thiel, R. Kuhn, K. Rajewsky, W. Muller, M. Assenmacher, and A. Radbruch. 1994. Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells. J. Exp. Med. 179:1349.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1349
-
-
Schmitz, J.1
Thiel, A.2
Kuhn, R.3
Rajewsky, K.4
Muller, W.5
Assenmacher, M.6
Radbruch, A.7
-
6
-
-
0026552626
-
An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals
-
Abe, E., R. De Waal Malefyt, I. Matsuda, K. Arai, and N. Arai. 1992. An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals. Proc. Natl. Acad. Sci. USA 89:2864.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2864
-
-
Abe, E.1
De Waal Malefyt, R.2
Matsuda, I.3
Arai, K.4
Arai, N.5
-
7
-
-
0026510627
-
T cell-specific negative regulation of transcription of the human cytokine IL-4
-
Li-Weber, M., A. Eder, H. Krafft-Czepa, and P. H. Krammer. 1992. T cell-specific negative regulation of transcription of the human cytokine IL-4. J. Immunol. 148:1913.
-
(1992)
J. Immunol.
, vol.148
, pp. 1913
-
-
Li-Weber, M.1
Eder, A.2
Krafft-Czepa, H.3
Krammer, P.H.4
-
8
-
-
0027305687
-
Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: Roles for NF-Y and NF-ATc
-
Szabo, S. J., J. S. Gold, T. L. Murphy, and K. M. Murphy. 1993. Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol. Cell. Biol. 13:4793.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4793
-
-
Szabo, S.J.1
Gold, J.S.2
Murphy, T.L.3
Murphy, K.M.4
-
9
-
-
0027360559
-
Molecular dissection of the mouse interleukin-4 promoter
-
Bruhn, K. W., K. Nelms, J. L. Boulay, W. E. Paul, and M. J. Lenardo. 1993. Molecular dissection of the mouse interleukin-4 promoter. Proc. Natl. Acad. Sci. USA 90:9707.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9707
-
-
Bruhn, K.W.1
Nelms, K.2
Boulay, J.L.3
Paul, W.E.4
Lenardo, M.J.5
-
10
-
-
0027251928
-
Transcription of the interleukin 4 gene is regulated by multiple promoter elements
-
Todd, M. D., M. J. Grusby, J. A. Lederer, E. Lacy, A. H. Lichtman, and L. H. Glimcher. 1993. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. J. Exp. Med. 177:1663.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1663
-
-
Todd, M.D.1
Grusby, M.J.2
Lederer, J.A.3
Lacy, E.4
Lichtman, A.H.5
Glimcher, L.H.6
-
11
-
-
0027714991
-
Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter
-
Chuvpilo, S., C. Schomberg, R. Gerwig, A. Heinfling, R. Reeves, F. Grummt, and E. Serfling. 1993. Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter. Nucleic Acids Res. 21:5694.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5694
-
-
Chuvpilo, S.1
Schomberg, C.2
Gerwig, R.3
Heinfling, A.4
Reeves, R.5
Grummt, F.6
Serfling, E.7
-
12
-
-
0027985435
-
The role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression
-
Li-Weber, M., I. V. Davydov, H. Krafft, and P. H. Krammer. 1994. The role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression. J. Immunol. 153:4122.
-
(1994)
J. Immunol.
, vol.153
, pp. 4122
-
-
Li-Weber, M.1
Davydov, I.V.2
Krafft, H.3
Krammer, P.H.4
-
13
-
-
0029030775
-
Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
-
Rooney, J. W., T. Hoey, and L. H. Glimcher. 1995. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 2:473.
-
(1995)
Immunity
, vol.2
, pp. 473
-
-
Rooney, J.W.1
Hoey, T.2
Glimcher, L.H.3
-
14
-
-
0029023580
-
The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors
-
Hodge, M. R., J. W. Rooney, and L. H. Glimcher. 1995. The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors. J. Immunol. 154:6397.
-
(1995)
J. Immunol.
, vol.154
, pp. 6397
-
-
Hodge, M.R.1
Rooney, J.W.2
Glimcher, L.H.3
-
15
-
-
0028889432
-
Nuclear factor-IL-6 activates the human IL-4 promoter in T cells
-
Davydov, I. V., P. H. Krammer, and M. Li-Weber. 1995. Nuclear factor-IL-6 activates the human IL-4 promoter in T cells. J. Immunol. 155:5273.
-
(1995)
J. Immunol.
, vol.155
, pp. 5273
-
-
Davydov, I.V.1
Krammer, P.H.2
Li-Weber, M.3
-
16
-
-
0028157768
-
A common factor regulates both Th1- and Th2-specific cytokine gene expression
-
Rooney, J. W., M. R. Hodge, P. G. McCaffrey, A. Rao, and L. H. Glimcher. 1994. A common factor regulates both Th1-and Th2-specific cytokine gene expression. EMBO J. 13:625.
-
(1994)
EMBO J.
, vol.13
, pp. 625
-
-
Rooney, J.W.1
Hodge, M.R.2
McCaffrey, P.G.3
Rao, A.4
Glimcher, L.H.5
-
17
-
-
0023821516
-
Identification of a putative regulator of early T cell activation genes
-
Shaw, J.-P., P. J. Utz, D. B. Durand, J. J. Toole, E. A. Emmel, and G. R. Crabtree. 1988. Identification of a putative regulator of early T cell activation genes. Science 241:202.
-
(1988)
Science
, vol.241
, pp. 202
-
-
Shaw, J.-P.1
Utz, P.J.2
Durand, D.B.3
Toole, J.J.4
Emmel, E.A.5
Crabtree, G.R.6
-
18
-
-
0028300431
-
NF-ATp: A transcription factor required for the co-ordinate induction of several cytokine genes
-
Rev.
-
Rao, A. 1994. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 15:274 (Rev.).
-
(1994)
Immunol. Today
, vol.15
, pp. 274
-
-
Rao, A.1
-
19
-
-
0027432388
-
Isolation of the cyclosporin-sensitive T cell transcription factor NFATp
-
McCaffrey, P. G., C. Luo, T. K. Kerppola, J. Jain, T. M. Badalian, A. M. Ho, E. Burgeon, W. S. Lane, J. N. Lambert, T. Curran, G. L. Verdine, A. Rao, and P. G. Hogan. 1993. Isolation of the cyclosporin-sensitive T cell transcription factor NFATp. Science 262:750.
-
(1993)
Science
, vol.262
, pp. 750
-
-
McCaffrey, P.G.1
Luo, C.2
Kerppola, T.K.3
Jain, J.4
Badalian, T.M.5
Ho, A.M.6
Burgeon, E.7
Lane, W.S.8
Lambert, J.N.9
Curran, T.10
Verdine, G.L.11
Rao, A.12
Hogan, P.G.13
-
20
-
-
0028361589
-
NF-AT components define a family of transcription factors targeted in T-cell activation
-
Northrop, J. P., S. N. Ho, L. Chen, D. J. Thomas, L. A. Timmerman, G. P. Nolan. A. Admon, and G. R. Crabtree. 1994. NF-AT components define a family of transcription factors targeted in T-cell activation [see comments]. Nature 369: 497.
-
(1994)
Nature
, vol.369
, pp. 497
-
-
Northrop, J.P.1
Ho, S.N.2
Chen, L.3
Thomas, D.J.4
Timmerman, L.A.5
Nolan, G.P.6
Admon, A.7
Crabtree, G.R.8
-
21
-
-
0028930843
-
NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus
-
Masuda, E. S., Y. Naito, H. Tokumitsu, D. Campbell, F. Saito, C. Hannum. K. Arai, and N. Arai. 1995. NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus. Mol. Cell Biol. 15:2697.
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 2697
-
-
Masuda, E.S.1
Naito, Y.2
Tokumitsu, H.3
Campbell, D.4
Saito, F.5
Hannum, C.6
Arai, K.7
Arai, N.8
-
22
-
-
0029053852
-
Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
-
Hoey, T., Y. L. Sun, K. Williamson, and X. Xu. 1995. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2:461.
-
(1995)
Immunity
, vol.2
, pp. 461
-
-
Hoey, T.1
Sun, Y.L.2
Williamson, K.3
Xu, X.4
-
23
-
-
0029008237
-
Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element
-
Tara, D., D. L. Weiss, and M. A. Brown. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element. J. Immunol. 154:4592.
-
(1995)
J. Immunol.
, vol.154
, pp. 4592
-
-
Tara, D.1
Weiss, D.L.2
Brown, M.A.3
-
24
-
-
0030604714
-
The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho, I. C., M. R. Hodge, J. W. Rooney, and L. H. Glimcher. 1996. The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973.
-
(1996)
Cell
, vol.85
, pp. 973
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
25
-
-
0026315351
-
Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40
-
Ullman, K. S., W. M. Flanagan, C. A. Edwards, and G. R. Crabtree. 1991. Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40. Science 254:558.
-
(1991)
Science
, vol.254
, pp. 558
-
-
Ullman, K.S.1
Flanagan, W.M.2
Edwards, C.A.3
Crabtree, G.R.4
-
26
-
-
0027975323
-
Regulation of cytokine gene expression in T helper cell subsets
-
Lederer, J. A., J. S. Liou, M. D. Todd, L. H. Glimcher, and A. H. Lichtman. 1994. Regulation of cytokine gene expression in T helper cell subsets. J. Immunol. 152:77.
-
(1994)
J. Immunol.
, vol.152
, pp. 77
-
-
Lederer, J.A.1
Liou, J.S.2
Todd, M.D.3
Glimcher, L.H.4
Lichtman, A.H.5
-
27
-
-
0026467244
-
A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer
-
Henkel, G., D. L. Weiss, R. McCoy, T. Deloughery, D. Tara, and M. A. Brown. 1992. A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J. Immunol. 149:3239.
-
(1992)
J. Immunol.
, vol.149
, pp. 3239
-
-
Henkel, G.1
Weiss, D.L.2
McCoy, R.3
Deloughery, T.4
Tara, D.5
Brown, M.A.6
-
28
-
-
0027939672
-
PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer
-
Henkel, G., and M. A. Brown. 1994. PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer. Proc. Natl. Acad. Sci. USA 91:7737.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7737
-
-
Henkel, G.1
Brown, M.A.2
-
29
-
-
0024002556
-
Luciferase reporter gene vectors for analysis of promoters and enhancers
-
Nordeen, S. K. 1988. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6:454.
-
(1988)
Biotechniques
, vol.6
, pp. 454
-
-
Nordeen, S.K.1
-
31
-
-
0021875276
-
Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1
-
Ohara, J., and W. E. Paul. 1985. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature 315:333.
-
(1985)
Nature
, vol.315
, pp. 333
-
-
Ohara, J.1
Paul, W.E.2
-
32
-
-
0026648380
-
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha-beta-T-cell-receptor transgenic system
-
Hsieh, C-S., A. B. Heimberger, J. S. Gold, A. O'Garra, and K. M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha-beta-T-cell-receptor transgenic system. Proc. Nutl. Acad. Sci. USA 89:6065.
-
(1992)
Proc. Nutl. Acad. Sci. USA
, vol.89
, pp. 6065
-
-
Hsieh, C.-S.1
Heimberger, A.B.2
Gold, J.S.3
O'Garra, A.4
Murphy, K.M.5
-
33
-
-
0029071483
-
Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
-
Szabo, S. J., N. G. Jacobson, A. S. Dighe, U. Gubler, and K. M. Murphy. 1995. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity 2:665.
-
(1995)
Immunity
, vol.2
, pp. 665
-
-
Szabo, S.J.1
Jacobson, N.G.2
Dighe, A.S.3
Gubler, U.4
Murphy, K.M.5
-
34
-
-
0019218668
-
IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement
-
Sarmiento, M., A. L. Glasebrook, and F. W. Fitch. 1980. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125:2665.
-
(1980)
J. Immunol.
, vol.125
, pp. 2665
-
-
Sarmiento, M.1
Glasebrook, A.L.2
Fitch, F.W.3
-
35
-
-
0023088643
-
Structural analysis of the mouse chromosomal gene encoding interleukin 4 which expresses B cell, T cell and mast cell stimulating activities
-
Otsuka, T., D. Villaret, T. Yokota, Y. Takebe, F. Lee, N. Arai, and K. Arai. 1987. Structural analysis of the mouse chromosomal gene encoding interleukin 4 which expresses B cell, T cell and mast cell stimulating activities. Nucleic Acids Res. 15:333.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 333
-
-
Otsuka, T.1
Villaret, D.2
Yokota, T.3
Takebe, Y.4
Lee, F.5
Arai, N.6
Arai, K.7
-
36
-
-
0003799070
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hogan, B., F. Constantini, and E. Lacy. 1986. Manipulating the Mouse Embryo. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. p. 1.
-
(1986)
Manipulating the Mouse Embryo
, pp. 1
-
-
Hogan, B.1
Constantini, F.2
Lacy, E.3
-
37
-
-
0010228473
-
Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection
-
Buchmeier, N. A., and R. D. Schreiber. 1985. Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 82:7404.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 7404
-
-
Buchmeier, N.A.1
Schreiber, R.D.2
-
38
-
-
0028445321
-
Cyclosporin-A sensitive induction of NF-AT in murine B cells
-
Venkataraman, L., D. A. Francis, Z. Wang, J. Liu, T. L. Rothstein, and R. Sen. 1994. Cyclosporin-A sensitive induction of NF-AT in murine B cells. Immunity 1:189.
-
(1994)
Immunity
, vol.1
, pp. 189
-
-
Venkataraman, L.1
Francis, D.A.2
Wang, Z.3
Liu, J.4
Rothstein, T.L.5
Sen, R.6
-
39
-
-
0028450096
-
Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4
-
Choi, M. S., R. D. Brines, M. J. Holman, and G. G. Klaus. 1994. Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. Immunity 1:179.
-
(1994)
Immunity
, vol.1
, pp. 179
-
-
Choi, M.S.1
Brines, R.D.2
Holman, M.J.3
Klaus, G.G.4
-
40
-
-
0029080794
-
Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: Regulation upon CD16 ligand binding
-
Aramburu, J., L. Azzoni, A. Rao, and B. Perussia. 1995. Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding. J. Exp. Med. 182:801.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 801
-
-
Aramburu, J.1
Azzoni, L.2
Rao, A.3
Perussia, B.4
-
41
-
-
0028245317
-
NF-AT-AP-1 and Rel-bZIP: Hybrid vigor and binding under the influence
-
Rev.
-
Nolan, G. P. 1994. NF-AT-AP-1 and Rel-bZIP: hybrid vigor and binding under the influence. Cell 77:795 (Rev.).
-
(1994)
Cell
, vol.77
, pp. 795
-
-
Nolan, G.P.1
-
42
-
-
0028938658
-
A similar DNA-binding motif in NFAT family proteins and the Rel homology region
-
Jain, J., E. Burgeon, T. M. Badalian, P. G. Hogan, and A. Rao. 1995. A similar DNA-binding motif in NFAT family proteins and the Rel homology region. J. Biol. Chem. 270:4138.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4138
-
-
Jain, J.1
Burgeon, E.2
Badalian, T.M.3
Hogan, P.G.4
Rao, A.5
-
43
-
-
0030002617
-
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice
-
Hodge, M. R., A. M. Ranger, F. C. de la Brousse, T. Hoey, M. J. Grusby, and L. H. Glimcher. 1996. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity 4:397.
-
(1996)
Immunity
, vol.4
, pp. 397
-
-
Hodge, M.R.1
Ranger, A.M.2
De La Brousse, F.C.3
Hoey, T.4
Grusby, M.J.5
Glimcher, L.H.6
-
44
-
-
0029882657
-
An enhanced immune response in mice lacking the transcription factor NFAT1
-
Abstr.
-
Xanthoudakis, S., J. P. B. Viola, K. T. Y. Shaw, C. Luo, J. D. Wallace, P. T. Bozza, T. Curran, and A. Rao. 1996. An enhanced immune response in mice lacking the transcription factor NFAT1. Science 272:892 (Abstr.).
-
(1996)
Science
, vol.272
, pp. 892
-
-
Xanthoudakis, S.1
Viola, J.P.B.2
Shaw, K.T.Y.3
Luo, C.4
Wallace, J.D.5
Bozza, P.T.6
Curran, T.7
Rao, A.8
-
45
-
-
0026734795
-
Sequences and factors: A guide to MHC class-II transcription
-
Rev.
-
Glimcher, L. H., and C. J. Kara. 1992. Sequences and factors: a guide to MHC class-II transcription. Annu. Rev. Immunol. 10:13 (Rev.).
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 13
-
-
Glimcher, L.H.1
Kara, C.J.2
|