Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common γ chain

Blood

Volumn 87, Issue 10, 1996, Pages 4286-4295

  Schnyder, Bruno ^b   Lugli, Serena ^b   Feng, Ningping ^b   Etter, Hansueli ^b   Lutz, Ruedi A ^b   Ryffel, Bernhard ^b   Sugamura, Kazuo ^b   Wunderli Allenspach, Heidi ^b   Moser, René ^a  

^a ETH ZURICH   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; MONOCLONAL ANTIBODY; RECEPTOR SUBUNIT; VASCULAR CELL ADHESION MOLECULE 1;

ANTIBODY SPECIFICITY; ANTIGEN EXPRESSION; ARTICLE; BINDING AFFINITY; CELL MIGRATION; CONTROLLED STUDY; CROSS LINKING; ENDOTHELIUM CELL; EOSINOPHILIA; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0029968650     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.10.4286.bloodjournal87104286     Document Type: Article

References (44)

1. Seminario MC, Gleich GJ: The role of eosinophils in the pathogenesis of asthma. Curr Opin Immunol 6:860, 1994
2. Sur S, Adolphson CR, Gleich GJ: Eosinophils: Biochemical and cellular aspects, in Middleton F, Reed CB, Ellis EF, Adkinson JNF, Yunginger JW, Busse W (eds): Allergy Principle and Practice. St Louis, MO, Mosby, 1993, p 169
3. Thornhill MH, Kyan-Aung U, Haskard DO: IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils. J Immunol 144:3060, 1990
4. Schleimer RP, Sterbinsky SA, Kaiser J, Bickel CA, Klunk DA, Tomioka K, Newman W, Luscinskas FW, Gimbrone MA Jr, McIntire BW, Bochner BS: IL-4 induces adherence of human eosinophils and basophils but not of neutrophils to endothelium. Association with expression of VCAM-1. J Immunol 148:1086, 1992
5. Sironi M, Sciacca LF, Matteucci C, Conni M, Vecchi A, Bernasconi S, Minty A, Caput D, Ferrara P, Collotta F, Mantovani A: Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood 84:1913, 1994
6. Bochner BS, Klunk DA, Sterbinsky SA, Coffman RL, Schleimer RP: IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J Immunol 154:799, 1995
7. Elices MJ, Osborn L, Takada Y, Grouse C, Luhowskyj S, Hemler ME, Lobb RR: VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60:577, 1990
8. Lobb RR, Hemler ME: The pathophysiologic role of a 4 integrins in vivo. J Clin Invest 94:1722, 1994
9. Moser R, Fehr J, Olgiati L, Bruijnzeel PLB: Migration of primed human eosinophils across cytokine-activated endothelial cell monolayers. Blood 79:30, 1992
10. Moser R, Fehr J, Bruijnzeel PLB: Interleukin-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J Immunol 149:1432, 1992
11. Moser R, Groscurth P, Carballido JM, Bruijnzeel PLB, Blaser K, Heusser CH, Fehr J: Interleukin-4 induces tissue eosinophilia in mice: Correlation with its in vitro capacity to stimulate the endothelial cell-dependent selective transmigration of human eosinophils. J Lab Clin Med 122:567, 1993
12. Keegan AD, Nelms K, Wang LM, Pierce JH, Paul WE: Interleukin-4 receptor: Signaling mechanisms. Immunol Today 15:423, 1994
13. Kondo M, Takeshita T, Ishii N, Nakamura M, Watanabe S, Arai K, Sugamura K: Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 262:1874, 1993
14. Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ: Interleukin-2 receptor γ chain: A functional component of the interleukin-7 receptor. Science 262:1877, 1993
15. Kishimoto T, Taga T, Akira S: Cytokine signal transduction. Cell 76:253, 1994
16. Kondo M, Takeshita T, Higuchi M, Nakamura M, Sudo T, Nishikawa S, Sugamura K: Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes. Science 263:1453, 1994
17. Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedman MC, Miyajima A, Puri RK, Paul WE, Leonard WJ: Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor. Science 262:1880, 1993
18. Zurawski SM, Vega F Jr, Huyglic B, Zurawski B: Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J 12:2663, 1993
19. Zurawski SM, Chomarat P, Djossou O, Bidault C, McKenzie ANJ, Miossec P, Banchereau J, Zurawski G: The primary binding site of the human interleukin-4 receptor is also a component of the IL-13 receptor. J Biol Chem 270:13869, 1995
20. Vita N, Lefort S, Laurent P, Caput D, Ferrara P: Characterization and comparison of the interleukin-13 receptor with the interleukin-4 receptor on several cell types. J Biol Chem 270:3512, 1995
21. Takeshita T, Ohtani K, Asao H, Kumaki S, Nakamura M, Sugamura K: An associated molecule, p64, with IL-2 receptor β-chain: Its possible involvement in the formation of the functional intermediate-affinity IL-2 receptor complex. J Immunol 148:2154, 1992
22. Ishii N, Takeshita T, Kimura Y, Tada K, Kondo M, Nakamura M, Sugamura K: Expression of the IL-2 receptor γ chain on various populations in human peripheral blood. Int Immunol 6:1273, 1994
23. Moser R, Schleiffenbaum B, Groscurth P, Fehr J: Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage. J Clin Invest 83:444, 1989
24. Fehr J, Moser R, Leppert D, Groscurth P: Antiadhesive properties of biological surfaces are protective against stimulated granulocytes. J Clin Invest 76:535, 1985
25. Hansel TT, Pound JD, Pilling D, Kitas GD, Salmon M, Gentle TA, Lee SS, Thompson RA: Purification of human blood eosinophils by negative selection using immunomagnetic beads. J Immunol Methods 122:97, 1989
26. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:152, 1987
27. Legoux P, Minty C, Delpech B, Minty AJ, Shire D: Simultaneous quantitation of cytokine mRNAs in interleukin-1β stimulated U373 human astrocytoma cells by a polymerisation chain reaction method involving co-amplification with an internal multispecific control. Eur Cytokine Netw 3:553, 1992
28. Shire D: An invitation to an open exchange of reagents and information useful for the measurement of cytokine mRNA levels by PCR. Eur Cytokine Netw 4:161, 1993
29. Munson PJ, Rodbard D: LIGAND: A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220, 1980
30. Palmer-Cracker RL, Pober JS: IL-4 induction of VCAM-1 on endothelial cells involves activation of a protein tyrosine kinase. J Immunol 154:2838, 1995
31. Aversa G, Punnonen J, Cocks BG, Malefyt RD, Vega F, Zurawski SM, Zurawski G, de Vries JE: An interleukin-4 (IL-4) mutant protein inhibits both IL-4 and IL-13-induced human immunoglobulin-G4 (IgG4) and IgE synthesis and B-cell proliferation: support for a common component shared by IL-4 and IL-13. J Exp Med 178:2213, 1993
32. Lahm H, Schnyder B, Wyniger J, Borbenyi Z, Yilmaz A, Car BD, Fischer JR, Givel JC, Ryffel B: Growth inhibition of human colorectal carcinoma cells by interleukin-4 and expression of functional interleukin-4 receptors. Int J Cancer 59:440, 1994
33. Keegan AD, Beckmann MP, Park LS, Paul WE: The IL-4 receptor: biochemical characterization of IL-4-binding molecules in a T cell line expressing large numbers of receptors. J Immunol 146:2272, 1991
34. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y: Genistein: A specific inhibitor of tyrosine-specific kinase. J Biol Chem 282:5592, 1987
35. Moser R: Transendothelial migration of eosinophils: Unanswered questions. Ann NY Acad Sci 725:156, 1994
36. Foxwell BM, Woerly G, Ryffel B: Identification of interleukin 4 receptor-associated proteins and expression of both high- and low-affinity binding on human lymphoid cells. Eur J Immunol 19:1637, 1989
37. Kruse N, Toni HP, Seebald W: Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement. EMBO J 11:3237, 1992
38. Mosley B, Beckmann MP, March CJ, Idzerda RL, Gimpel SD, VandenBos T, Friend D, Alpert A, Anderson D, Jackson J, Wignall JM, Smith C, Gallis B, Sims JE, Urdal D, Widmer MB, Cosman D, Park SL: The murine IL-4 receptor: Molecular cloning and characterization of of secreted and membrane bound forms. Cell 89:335, 1989
39. Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, Park LS: Cloning of the human and murine interleukin 7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. Cell 90:941, 1990
40. He YW, Adkins B, Furse RK, Malek TR: Expression and function of the gamma(c) subunit of the IL-2, IL-4, and IL-7 receptors-Distinct interaction of gamma(c) in the IL-4 receptor. J Immunol 154:1596, 1995
41. c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor. J Immunol 155:9, 1995
42. Obiri NI, Debinsky W, Leonard WJ, Pun RK: Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common y chain shared by receptors for interleukin 2, 4, 7, 9, and 15. J Biol Chem 270:8797, 1995
43. Smerz-Bertling C, Duschl A: Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140 kD subunit of the interleukin 4 receptor. J Biol Chem 270:966, 1995
44. Welham M J, Learmonth L, Bone H, Schrader J W: Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with IL-4 and insulin. J Biol Chem 270:12286, 1995