Inhibition of proliferation and clonal growth of human breast cancer cells by interleukin 13

Cancer Research

Volumn 56, Issue 15, 1996, Pages 3583-3588

  Serve, Hubert ^a   Oelmann, Elisabeth ^a   Herweg, Alexander ^a   Oberberg, Dorothea ^a   Serve, Susanne ^a   Reufi, Birgit ^a   Mücke, Carola ^a   Minty, Adrian ^b   Thiel, Eckhard ^a   Berdel, Wolfgang E ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN RECEPTOR; RECOMBINANT INTERLEUKIN 13;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; BREAST CANCER; CANCER IMMUNOTHERAPY; CELL PROLIFERATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BINDING SITES; BREAST NEOPLASMS; CELL CYCLE; CELL DIVISION; CHO CELLS; CRICETINAE; DNA, NEOPLASM; HUMANS; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-4; IODINE RADIOISOTOPES; MOLECULAR SEQUENCE DATA; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-13; RECEPTORS, INTERLEUKIN-4; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 8044257147     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Brown, K. D., Zurawski, S. M., Mosmann, T. R., and Zurawski, G. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes. J. Immunol., 142: 679-687, 1989.
2. Minty, A., Chalon, P., Derocq, J. M., Dumont, X., Guillemot, J. C., Kaghad, M., Labit, C., Leplatois, P., Liauzun, P., Miloux, B., Minty, C., Casellas, P., Loison, G., Lupker, J., Shire, D., Ferrara, P., and Caput, D. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature (Lond.), 362: 248-250, 1993.
3. McKenzie, A. N., Culpepper, J. A., de Waal Malefyt, R., Briere, F., Punnonen, J., Aversa, G., Sato, A., Dang, W., Cocks, B. G., Menon, S., de Vries, J. E., Bachereau, J., and Zurawski, G. Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc. Natl. Acad. Sci. USA, 90: 3735-3739, 1993.
4. McKenzie, A. N., Li, X., Largaespada, D. A., Sato, A., Kaneda, A., Zurawski, S. M., Doyle, E. L., Milatovich, A., Francke, U., Copeland, N. G., Jenkins, N. A., and Zurawski, G. Structural comparison and chromosomal localization of the human and mouse IL-13 genes. J. Immunol., 150: 5436-5444, 1993.
5. Smirnov, D. V., Smirnova, M. G., Korobko, V. G., and Frolova, E. I. Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization Gene, 155: 277-281, 1995.
6. Punnonen, J., Aversa, G., Cocks, B. G., McKenzie, A. N., Menon, S., Zurawski, G., de Waal Malefyt, R., and de Vries, J. E. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. USA, 90: 3730-3734, 1993.
7. Punnonen, J., and de Vries, J. E. IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells. J. Immunol., 152: 1094-1102, 1994.
8. Zurawski, S. M., Vega, F. J., Huyghe, B., and Zurawski, G. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J., 12: 2663-2670, 1993.
9. Kondo, M., Takeshita, T., Ishii, N., Nakamura, M., Watanabe, S., Arai, K., and Sugamura, K. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science (Washington DC), 262: 1874-1877, 1993.
10. Russell, S. M., Keegan, A. D., Harada, N., Nakamura, Y., Noguchi, M., Leland, P., Friedmann, M. C., Miyajima, A., Puri, R. K., Paul, W. E., and Leonard, W. Interleukin-receptor gamma chain: a functional component of the interleukin-4 receptor. Science (Washington DC), 262: 1880-1883, 1993.
11. Matthews, D. J., Clark, P. A., Herbert, J., Morgan, G., Armitage, R. J., Kinnon, C., Minty, A., Grabstein, K. H., Caput, D., Ferrara, P., and Callard, R. Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood, 85: 38-42, 1995.
12. Obiri, N. I., Debinski, W., Leonard, W. J., and Puri, R. K. Receptor for interleukin 13 J. Biol. Chem., 270: 8797-8804, 1995.
13. He, Y. W., and Malek, T. R. The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor. J. Immunol., 155: 9-12, 1995.
14. Jacobsen, S. E., Okkenhaug, C., Veiby, O. P., Caput, D., Ferrara, P., and Minty, A. Interleukin 13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells. J. Exp. Med., 180: 75-82, 1994.
15. Xi, X., Schlegel, N., Caen, J. P., Minty, A., Fournier, S., Caput, D., Ferrara, P., and Han, Z. C. Differential effects of recombinant human interleukin-13 on the in vitro growth of human haemopoietic progenitor cells. Br. J. Haematol., 90: 921-927, 1995.
16. Nilsson, G., and Nilsson, K. Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4. Eur. J. Immunol., 25: 870-873, 1995.
17. Lind, M., Deleuran, B., Yssel, H., Fink, E. E., and Thestrup, P. K. IL-4 and IL-13, but not IL-10, are chemotactic factors for human osteoblasts. Cytokine, 7: 78-82, 1995.
18. Bochner, B. S., Klunk, D. A., Sterbinsky, S. A., Coffman, R. L., and Schleimer, R. P. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J. Immunol., 154: 799-803, 1995.
19. Sironi, M., Sciacca, F. L., Matteucci, C., Conni, M., Vecchi, A., Bernasconi, S., Minty, A., Caput, D., Ferrara, P., Colotta, F., and Mantovani, A. Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood, 84: 1913-1921, 1994.
20. Derocq, J. M., Segui, M., Poinot, C. C., Minty, A., Caput, D., Ferrara, P., and Casellas, P. Interleukin-13 stimulates interleukin-6 production by human keratinocytes. Similarity with interleukin-4. FEBS Lett., 3439: 32-36, 1994.
21. Topp, M., Papadimitriou, C. A., Eitelbach, F., Oelmann, E., Koehler, B., Oberberg, D., von Marschall, Z., Reufi, B., Stein, H., Thiel, E., Winton, E. F., and Berdel, W. E. Antiproliferative effect of human interleukin-4 in human cancer cell lines studies on the mechanism. Leuk. & Lymphoma, 19: 319-328, 1995.
22. Topp, M. S., Papadimitriou, C. A., Eitelbach, F., Koenigsmann, M., Oelmann, E., Koehler, B., Oberberg, D., Reufi, B., Stein, H., Thiel, E., and Berdel, W. E. Recombinant human interleukin 4 has antiproliferative activity on human tumor cell lines derived from epithelial and nonepithelial histologies. Cancer Res., 55: 2173-2176, 1995.
23. Topp, M., Koenigsmann, M., Mire-Sluis, A., Oberberg, D., Eitelbach, F., von Marshall, Z., Notter, M., Reufi, B., Stein, H., Thiel, E., and Berdel, W. E. Recombinant human interleukin-4 inhibits growth of some human lung tumor cell lines in vitro and in vivo. Blood, 82: 2837-2844, 1993.
24. Hoon, D. S. B., Okun, E., Banez, M., Irie, R. F., and Morton, D. L. Interleukin 4 alone and with γ-interferon or α-tumor necrosis factor inhibits cell growth and modulates cell surface antigens on human renal cell carcinomas. Cancer Res., 51: 5687-5693, 1991.
25. Obin, N. I., Hillman, G. G., Haas, G. P., Sud, S., and Puri, R. K. Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4. J. Clin. Invest., 91: 88-93, 1993.
26. Tot, M., Bicknell, R., and Harris, A. L. Inhibition of colon and breast carcinoma cell growth by interleukin-4. Cancer Res., 52: 275-279, 1992.
27. Kruse, N., Tony, H-P., and Sebald, W. Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement. EMBO J., 11: 3237-3244, 1992.
28. Scatchard, G. The attractions of proteins for small molecules and ions. Ann. N. Y. Acad. Sci., 51: 660-672, 1949.
29. Takeshita, T., Asao, H., Ohtani, K., Ishii, N., Kumaki, S., Tanaka, N., Munakata, H., Nakamura, M., and Sugamura, K. Cloning of the gamma chain of the human IL-2 receptor. Science (Washington DC), 257: 379-382, 1992.
30. Slamon, D. J., Godolphin, W., Jones, L. A., Holt, J. A., Wong, S. G., Udove, J., Ullrich, A., and Press, M. F. Studies of the HER-2/neu protooncogene in human breast and ovarian cancer. Science (Washington DC), 244: 707-712, 1989.
31. Longmore, G. D., and Lodish, H. F. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice, a cytokine receptor superfamily oncogene. Cell, 67: 1089-1102, 1991.
32. Gross, J. L., Behrens, D. L., Mullins, D. E., Kornblith, P. L., and Dexter, D. L. Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. Cancer Res., 48: 291-296, 1988.
33. Freedman, V. H., and Shin, S. Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell, 3: 355-359, 1974.
34. Vita, N., Lefort, S., Laurent, P., Caput, D., and Ferrara, P. Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types. J. Biol. Chem., 270: 3512-3517, 1995.
35. Hilton, D. J., Zhang, J-G., Metcalf, D., Alexander, W. S., Nicola, N. A., and Willson, T. A. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. USA, 93: 497-501, 1996.
36. He, Y-W., Adkins, B., Furse, R. K., and Malek, T. R. Expression and function of the γc subunit of the IL-2, IL-4, and IL-7 receptors. J. Immunol., 154: 1596-1605, 1995.