메뉴 건너뛰기




Volumn 15, Issue 17, 1996, Pages 4506-4514

Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor α subunit

Author keywords

Interleukin 4; JAK STAT; Receptor; Signal transduction; Specificity

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; PHENYLALANINE; RECEPTOR SUBUNIT; TYROSINE;

EID: 0029834119     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00828.x     Document Type: Article
Times cited : (70)

References (53)
  • 1
    • 0024394549 scopus 로고
    • Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson, S., Davis, D.L., Dahlback, H., Jornvall, H. and Russell, D.W. (1989) Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem., 264, 8222-8229.
    • (1989) J. Biol. Chem. , vol.264 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlback, H.3    Jornvall, H.4    Russell, D.W.5
  • 2
    • 0003362578 scopus 로고
    • Interleukin-4
    • Thompson, A.W. (ed.), Academic Press Ltd, San Diego, CA
    • Banchereau, J. and Rybak, M.E. (1994) Interleukin-4. In Thompson, A.W. (ed.), The Cytokine Handbook. Academic Press Ltd, San Diego, CA, pp. 99-126.
    • (1994) The Cytokine Handbook , pp. 99-126
    • Banchereau, J.1    Rybak, M.E.2
  • 3
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan, J.-F. (1990) Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl Acad. Sci. USA, 87, 6934-6938.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6934-6938
    • Bazan, J.-F.1
  • 6
    • 0024160860 scopus 로고
    • Synergistic effects of purified recombinant human and murine B cell growth factor-1/IL-4 on colony formation in vitro by hematopoietic progenitor cells
    • Broxmeyer, H.E., Lu, L., Cooper, S., Tushinski, R., Mochizuki, D., Rubin, B.Y., Gillis, S. and Williams, D.E. (1988) Synergistic effects of purified recombinant human and murine B cell growth factor-1/IL-4 on colony formation in vitro by hematopoietic progenitor cells. J. Immunol. 141, 3852-3862.
    • (1988) J. Immunol. , vol.141 , pp. 3852-3862
    • Broxmeyer, H.E.1    Lu, L.2    Cooper, S.3    Tushinski, R.4    Mochizuki, D.5    Rubin, B.Y.6    Gillis, S.7    Williams, D.E.8
  • 7
    • 0028925778 scopus 로고
    • Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
    • Cao, X. et al. (1995) Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity, 2, 223-238.
    • (1995) Immunity , vol.2 , pp. 223-238
    • Cao, X.1
  • 8
    • 0028878330 scopus 로고
    • Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
    • DiSanto, J.P., Muller, W., Guy-Grand, D., Fischer, A. and Rajewsky, K. (1995) Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl Acad. Sci. USA, 92, 377-381.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 377-381
    • DiSanto, J.P.1    Muller, W.2    Guy-Grand, D.3    Fischer, A.4    Rajewsky, K.5
  • 9
    • 0029021518 scopus 로고
    • Heterodimerization and functional interaction between EGF receptor family members: A new signaling paradigm with implications for breast cancer research
    • Earp, H.S., Dawson, T.L., Li, X. and Yu, H. (1995) Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res. Treatment, 35, 115-132.
    • (1995) Breast Cancer Res. Treatment , vol.35 , pp. 115-132
    • Earp, H.S.1    Dawson, T.L.2    Li, X.3    Yu, H.4
  • 10
    • 0029093023 scopus 로고
    • IL4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-γ activation site-like sequence upstream of the 1e exon in a human B cell line
    • Fenghao, X., Saxon, A., Nguyen, A., Ke, Z., Diaz-Sanchez, D. and Nel, A. (1995) IL4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-γ activation site-like sequence upstream of the 1e exon in a human B cell line. J. Clin. Invest., 96, 907-914.
    • (1995) J. Clin. Invest. , vol.96 , pp. 907-914
    • Fenghao, X.1    Saxon, A.2    Nguyen, A.3    Ke, Z.4    Diaz-Sanchez, D.5    Nel, A.6
  • 11
    • 0029813118 scopus 로고    scopus 로고
    • Distinct tyrosine residues within the IL-2 receptor β chain drive signal transduction specificity, redundancy and diversity
    • in press
    • Gaffen, S.L., Lai, S.Y., Ha, M., Liu, X., Hennighausen, L., Greene, W.C. and Goldsmith, M.A. (1996) Distinct tyrosine residues within the IL-2 receptor β chain drive signal transduction specificity, redundancy and diversity. J. Biol. Chem., in press.
    • (1996) J. Biol. Chem.
    • Gaffen, S.L.1    Lai, S.Y.2    Ha, M.3    Liu, X.4    Hennighausen, L.5    Greene, W.C.6    Goldsmith, M.A.7
  • 12
    • 0028221433 scopus 로고
    • Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15
    • Giri, J.G. et al. (1994) Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J., 13, 2822-2830.
    • (1994) EMBO J. , vol.13 , pp. 2822-2830
    • Giri, J.G.1
  • 13
    • 0028332867 scopus 로고
    • The cytoplasmic domain of the IL-2 receptor β chain contains both unique and functionally redundant signal transduction elements
    • Goldsmith, M.A., Xu, W., Amaral, M.C., Kuczek, E.S. and Greene, W.C. (1994) The cytoplasmic domain of the IL-2 receptor β chain contains both unique and functionally redundant signal transduction elements J. Biol. Chem., 269, 14698-14704.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14698-14704
    • Goldsmith, M.A.1    Xu, W.2    Amaral, M.C.3    Kuczek, E.S.4    Greene, W.C.5
  • 15
    • 0029032061 scopus 로고
    • c chain does not function as a subunit shared by the IL-4 and IL-13 receptors: Implication for the structure of the IL-4 receptor
    • c chain does not function as a subunit shared by the IL-4 and IL-13 receptors: implication for the structure of the IL-4 receptor J. Immunol., 155, 9-12.
    • (1995) J. Immunol. , vol.155 , pp. 9-12
    • He, Y.-W.1    Malek, T.R.2
  • 16
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the IL-13 receptor that is also a component of the IL-4 receptor
    • Hilton, D.J., Zhang, J.-G., Metcalf, D., Alexander, W.S., Nicola, N.A. and Willson, T.A. (1996) Cloning and characterization of a binding subunit of the IL-13 receptor that is also a component of the IL-4 receptor. Proc. Natl Acad. Sci. USA, 93, 497-501.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 497-501
    • Hilton, D.J.1    Zhang, J.-G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Willson, T.A.6
  • 18
    • 0027968558 scopus 로고
    • Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signaling
    • Kawahara, A., Minami, Y. and Taniguchi, T. (1994) Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signaling. Mol. Cell Biol., 14, 5433-5440.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 5433-5440
    • Kawahara, A.1    Minami, Y.2    Taniguchi, T.3
  • 19
    • 0029115353 scopus 로고
    • Critical role of the IL-2 receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction
    • Kawahara, A., Minami, Y., Miyazaki, T., Ihle, J.N. and Taniguchi, T. (1995) Critical role of the IL-2 receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction. Proc. Natl Acad. Sci. USA, 92, 8724-8728.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 8724-8728
    • Kawahara, A.1    Minami, Y.2    Miyazaki, T.3    Ihle, J.N.4    Taniguchi, T.5
  • 22
    • 0028341465 scopus 로고
    • Human IL-13 activates the IL-4-dependent transcription factor NF-IL4 sharing a DNA binding motif with an interferon-γ-induced nuclear binding factor
    • Kohler, I., Alliger, P., Minty, A., Caput, D., Ferrara, P., Holl-Neugebauer, B., Rank, G. and Rieber, E.P. (1994) Human IL-13 activates the IL-4-dependent transcription factor NF-IL4 sharing a DNA binding motif with an interferon-γ-induced nuclear binding factor. FEBS Lett., 345, 187-192.
    • (1994) FEBS Lett. , vol.345 , pp. 187-192
    • Kohler, I.1    Alliger, P.2    Minty, A.3    Caput, D.4    Ferrara, P.5    Holl-Neugebauer, B.6    Rank, G.7    Rieber, E.P.8
  • 23
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
    • Kondo, M., Takeshita, T., Ishii, N., Nakamura, M., Watanabe, S., Arai, K.-I. and Sugamura, K. (1993) Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science, 262, 1874-1877.
    • (1993) Science , vol.262 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3    Nakamura, M.4    Watanabe, S.5    Arai, K.-I.6    Sugamura, K.7
  • 24
    • 0028327550 scopus 로고
    • Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes
    • Kondo, M., Takeshita, T., Higuchi, M., Nakamura, M., Sudo, T., Nishikawa, S. and Sugamura, K. (1994) Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes. Science, 263, 1453-1454.
    • (1994) Science , vol.263 , pp. 1453-1454
    • Kondo, M.1    Takeshita, T.2    Higuchi, M.3    Nakamura, M.4    Sudo, T.5    Nishikawa, S.6    Sugamura, K.7
  • 27
    • 0029054073 scopus 로고
    • IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells
    • Lefort, S., Vita, N., Reeb, R., Caput, D. and Ferrara, P. (1995) IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells. FEBS Lett., 366, 122-126.
    • (1995) FEBS Lett. , vol.366 , pp. 122-126
    • Lefort, S.1    Vita, N.2    Reeb, R.3    Caput, D.4    Ferrara, P.5
  • 28
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
    • Lin, J.-X. et al. (1995) The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity, 2, 331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.-X.1
  • 29
    • 0028901042 scopus 로고
    • Activation of JAK3, but not JAK1, is critical to IL4 stimulated proliferation and requires a membrane-proximal region of IL4 receptor α
    • Malabarba, M.G., Kirken, R.A., Rui, H., Koettnitz, K., Kawamura, M., O'Shea, J.J., Kalthoff, F.S. and Farrar, W.L. (1995) Activation of JAK3, but not JAK1, is critical to IL4 stimulated proliferation and requires a membrane-proximal region of IL4 receptor α. J. Biol. Chem., 270, 9630-9637.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9630-9637
    • Malabarba, M.G.1    Kirken, R.A.2    Rui, H.3    Koettnitz, K.4    Kawamura, M.5    O'Shea, J.J.6    Kalthoff, F.S.7    Farrar, W.L.8
  • 30
    • 0028797453 scopus 로고
    • Function of the IL-2 receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15
    • Matthews, D.J. et al. (1995) Function of the IL-2 receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood, 85, 38-42.
    • (1995) Blood , vol.85 , pp. 38-42
    • Matthews, D.J.1
  • 32
    • 0024317761 scopus 로고
    • The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms
    • Mosley, B. et al. (1989) The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell, 59, 335-348.
    • (1989) Cell , vol.59 , pp. 335-348
    • Mosley, B.1
  • 34
    • 0029557497 scopus 로고    scopus 로고
    • Receptors for IL-4 do not associate with the common γ chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells
    • Murata, T., Noguchi, P.D. and Puri, R.K. (1996) Receptors for IL-4 do not associate with the common γ chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells. J. Biol. Chem., 270, 30829-30836.
    • (1996) J. Biol. Chem. , vol.270 , pp. 30829-30836
    • Murata, T.1    Noguchi, P.D.2    Puri, R.K.3
  • 35
    • 0027751556 scopus 로고
    • Interleukin-2 receptor γ chain: A functional component of the interleukin-7 receptor
    • Noguchi, M., Nakamura, Y., Russell, S.M., Ziegler, S.F., Tsang, M., Cao, X. and Leonard, W.J. (1993a) Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science, 262, 1877-1880.
    • (1993) Science , vol.262 , pp. 1877-1880
    • Noguchi, M.1    Nakamura, Y.2    Russell, S.M.3    Ziegler, S.F.4    Tsang, M.5    Cao, X.6    Leonard, W.J.7
  • 38
    • 0029550822 scopus 로고
    • Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
    • Park, S.Y. et al. (1995) Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity, 3, 771-782.
    • (1995) Immunity , vol.3 , pp. 771-782
    • Park, S.Y.1
  • 39
    • 0027320217 scopus 로고
    • The interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency. SCIDX1
    • Puck, J.M., Deschenes, S.M., Porter, J.C., Dutra, A.S., Brown, C.J., Willard, H.F. and Henthorn, P.S. (1993) The interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency. SCIDX1. Hum. Mol. Genet., 2, 1099-1104.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 1099-1104
    • Puck, J.M.1    Deschenes, S.M.2    Porter, J.C.3    Dutra, A.S.4    Brown, C.J.5    Willard, H.F.6    Henthorn, P.S.7
  • 40
    • 0027787877 scopus 로고
    • Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor
    • Russell, S.M. et al. (1993) Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science, 262, 1880-1883.
    • (1993) Science , vol.262 , pp. 1880-1883
    • Russell, S.M.1
  • 41
    • 0028857954 scopus 로고
    • Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
    • Russell, S.M. et al. (1995) Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science, 270, 797-800.
    • (1995) Science , vol.270 , pp. 797-800
    • Russell, S.M.1
  • 42
    • 0029885698 scopus 로고    scopus 로고
    • Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor
    • Ryan, J.J., McReynolds, L.J., Keegan, A., Wang, L.-H., Garfein, E., Rothman, P., Nelms, K. and Paul, W.E. (1996) Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor. Immunity, 4, 123-132.
    • (1996) Immunity , vol.4 , pp. 123-132
    • Ryan, J.J.1    McReynolds, L.J.2    Keegan, A.3    Wang, L.-H.4    Garfein, E.5    Rothman, P.6    Nelms, K.7    Paul, W.E.8
  • 43
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J. and Ullrich, A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron, 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 44
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber, E., Matthias, P., Muller, M.M. and Schaffer, W. (1989) Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res., 17, 6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffer, W.4
  • 45
    • 0028289302 scopus 로고
    • Mutational analysis of a critical signaling domain of the human interleukin 4 receptor
    • Seldin, D.C. and Leder, P. (1994) Mutational analysis of a critical signaling domain of the human interleukin 4 receptor. Proc. Natl Acad. Sci. USA, 91, 2140-2144.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 2140-2144
    • Seldin, D.C.1    Leder, P.2
  • 47
    • 0027163933 scopus 로고
    • IL-4 suppresses IL-2 and interferon-γ production by naive T cells stimulated by accessory cell-dependent receptor engagement
    • Tanaka, T., Hu-Li, J., Seder, R.A., Fazekas de St Groth, B. and Paul, W.E. (1993) IL-4 suppresses IL-2 and interferon-γ production by naive T cells stimulated by accessory cell-dependent receptor engagement. Proc. Natl Acad. Sci. USA, 90, 5914-5918.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 5914-5918
    • Tanaka, T.1    Hu-Li, J.2    Seder, R.A.3    Fazekas De St Groth, B.4    Paul, W.E.5
  • 48
    • 0024516721 scopus 로고
    • Mechanism of interleukin-2 signaling: Mediation of different outcomes by a single receptor and transduction pathway
    • Tigges, M.A., Casey, L.S. and Koshland, M.E. (1989) Mechanism of interleukin-2 signaling: mediation of different outcomes by a single receptor and transduction pathway. Science, 243, 781-786.
    • (1989) Science , vol.243 , pp. 781-786
    • Tigges, M.A.1    Casey, L.S.2    Koshland, M.E.3
  • 49
    • 0029974563 scopus 로고    scopus 로고
    • IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor α chain
    • Wang, H.Y., Paul, W.E. and Keegan, A.D. (1996) IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor α chain. Immunity, 4, 113-121.
    • (1996) Immunity , vol.4 , pp. 113-121
    • Wang, H.Y.1    Paul, W.E.2    Keegan, A.D.3
  • 50
    • 0027507755 scopus 로고
    • IRS-1: Essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells
    • Wang, L.-M., Myers, M.G., Sun, X.-J., Aaronson, S.A., White, M. and Pierce, J.H. (1993) IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells. Science, 261, 1591-1594.
    • (1993) Science , vol.261 , pp. 1591-1594
    • Wang, L.-M.1    Myers, M.G.2    Sun, X.-J.3    Aaronson, S.A.4    White, M.5    Pierce, J.H.6
  • 51
    • 0028818459 scopus 로고    scopus 로고
    • The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2Rγ chain is involved in interleukin-13-mediated signal transduction
    • Wang, L.-M. et al. (1996) The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2Rγ chain is involved in interleukin-13-mediated signal transduction. Blood, 86, 4218-4227.
    • (1996) Blood , vol.86 , pp. 4218-4227
    • Wang, L.-M.1
  • 52
    • 0023612335 scopus 로고
    • Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor
    • Widmer, M.B., Acres, R.B., Sassenfeld, H.M. and Grabstein, K.H. (1987) Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. J. Exp. Med., 166, 1447-1455.
    • (1987) J. Exp. Med. , vol.166 , pp. 1447-1455
    • Widmer, M.B.1    Acres, R.B.2    Sassenfeld, H.M.3    Grabstein, K.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.