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Volumn 8, Issue 3, 1998, Pages 355-363

Beyond complete genomes: From sequence to structure and function

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN;

EID: 0032102671     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(98)80070-5     Document Type: Article
Times cited : (139)

References (60)
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    • The catalytic domain of the P-type ATPase has the haloacid dehalogenase fold
    • of special interest. This paper is an example of the application of sequence profile analysis to the prediction of the 3D fold and the catalytic residues in a critically important enzyme. P-ATPase, which has defied crystallization attempts and remained poorly characterized in spite of intense effort.
    • Aravind L, Galperin MY, Koonin EV. The catalytic domain of the P-type ATPase has the haloacid dehalogenase fold. of special interest Trends Biochem Sci. 23:1998;127-129 This paper is an example of the application of sequence profile analysis to the prediction of the 3D fold and the catalytic residues in a critically important enzyme. P-ATPase, which has defied crystallization attempts and remained poorly characterized in spite of intense effort.
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    • Aravind, L.1    Galperin, M.Y.2    Koonin, E.V.3
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    • PEDANTic genome analysis
    • of special interest. This paper describes a very convenient Worldwide Web site compiling results of automatic analysis of all available complete genomes. The Pedant WWW site (http://pedant.mips.biochem.mpg.de/frishman/pedant.html) is arguably one of the best entry points to comparative genomics but it has to be kept in mind that it is only the first level, crude analysis that is presented here.
    • Frishman D, Mewes HW. PEDANTic genome analysis. of special interest Trends Genet. 13:1997;415-416 This paper describes a very convenient Worldwide Web site compiling results of automatic analysis of all available complete genomes. The Pedant WWW site (http://pedant.mips.biochem.mpg.de/frishman/pedant.html) is arguably one of the best entry points to comparative genomics but it has to be kept in mind that it is only the first level, crude analysis that is presented here.
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    • Frishman, D.1    Mewes, H.W.2
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    • Assigning folds to the proteins encoded by the genome of Mycoplasma genitalium
    • of special interest. One of the first systematic attempts to predict the 3D structures of proteins starting from a complete genome. The utility of sequence - structure threading is demonstrated but it also becomes clear that such methods at best result in a rather small, incremental improvement over state-of-the-art sequence comparisons. Although the fraction of the proteins with a predictable fold is only 22% of the gene products, the authors predict by extrapolation that it should be possible to assign folds to most soluble proteins within a decade.
    • Fischer D, Eisenberg D. Assigning folds to the proteins encoded by the genome of Mycoplasma genitalium. of special interest Proc Natl Acad Sci USA. 94:1997;11929-11934 One of the first systematic attempts to predict the 3D structures of proteins starting from a complete genome. The utility of sequence - structure threading is demonstrated but it also becomes clear that such methods at best result in a rather small, incremental improvement over state-of-the-art sequence comparisons. Although the fraction of the proteins with a predictable fold is only 22% of the gene products, the authors predict by extrapolation that it should be possible to assign folds to most soluble proteins within a decade.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11929-11934
    • Fischer, D.1    Eisenberg, D.2
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    • 0031000649 scopus 로고    scopus 로고
    • An evolutionary treasure: Unification of a broad set of amidohydrolases related to urease
    • of special interest. A valuable example of a combination of detailed sequence analysis with structure - structure comparisons resulting in the characterization of a vast protein superfamily.
    • Holm L, Sander C. An evolutionary treasure: unification of a broad set of amidohydrolases related to urease. of special interest Proteins. 28:1997;72-82 A valuable example of a combination of detailed sequence analysis with structure - structure comparisons resulting in the characterization of a vast protein superfamily.
    • (1997) Proteins , vol.28 , pp. 72-82
    • Holm, L.1    Sander, C.2
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    • Identification of a novel phosphatase sequence motif
    • Stukey J, Carman GM. Identification of a novel phosphatase sequence motif. Protein Sci. 6:1997;469-472.
    • (1997) Protein Sci , vol.6 , pp. 469-472
    • Stukey, J.1    Carman, G.M.2
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    • An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases
    • Neuwald AF. An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases. Protein Sci. 6:1997;1764-1767.
    • (1997) Protein Sci , vol.6 , pp. 1764-1767
    • Neuwald, A.F.1
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    • A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/thiol ligase activity
    • Galperin MY, Koonin EV. A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/thiol ligase activity. Protein Sci. 6:1997;2639-2643.
    • (1997) Protein Sci , vol.6 , pp. 2639-2643
    • Galperin, M.Y.1    Koonin, E.V.2
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    • A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease
    • Aravind L, Koonin EV. A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci. 23:1998;17-19.
    • (1998) Trends Biochem Sci , vol.23 , pp. 17-19
    • Aravind, L.1    Koonin, E.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.