An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases

Protein Science

Volumn 6, Issue 8, 1997, Pages 1764-1767

  Neuwald, Andrew F ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Aur1p; Bromoperoxidase; Dri42; PAP2; PgpB; Vanadate

Indexed keywords

PEROXIDASE; PHOSPHATIDATE PHOSPHATASE; VANADIC ACID;

CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0030753213     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560060817     Document Type: Review

References (30)

1. Barila D, Plateroti M, Nobili F, Muda AO, Xie Y, Morimoto T, Perozzi G. 1996. The Dri 42 gene, whose expression is up-regulated during epithelial differentiation, encodes a novel endoplasmic reticulum resident transmembrane protein. J Biol Chem 271:29928-29936.
2. Brindley DN, Waggoner DW. 1996. Phosphatidate phosphohydrolase and signal transduction. Chem Phys Lipids 80:45-51.
3. Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. 1996. Visualization of intermediate and transition-state structures in protein-tyrosine pbosphatase catalysis. Proc Natl Acad Sci USA 93:2493-2498.
4. Dillon DA, Wu WI, Riedel B, Wissing JB, Dowhan W, Carman GM. 1996. The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity. J Biol Chem 271:30548-30553.
5. English D, Cui Y, Siddiqui RA. 1996. Messenger functions of phosphatidic acid. Chem Phys Lipids 80:117-132.
6. Exton JH. 1994. Phosphatidylcholine breakdown and signal transduction. Biochim Biophys Acta 1212:26-42.
7. Flores I, Casaseca T, Martinez AC, Kanoh H, Merida I. 1996. Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation. J Biol Chem 271:10334-10340.
8. Hashida-Okado T, Ogawa A, Endo M, Yasumoto R, Takesako K, Kato I. 1996. AUR1, a novel gene conferring aureobasidin resistance on Saccharomyces cerevisiae: A study of defective morphologies in Aur1p-depleted cells. Mol Gen Genet 251:216-244.
9. 2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase. J Biol Chem 271:18931-18938.
10. Kanoh H, Kai M, Wada I. 1996. Molecular properties of enzymes involved in diacylglycerol and phosphatidate metabolism. J Lipid Medial Cell Signal 14:245-250.
11. Karlin S, Altschul SF. 1993. Applications and statistics for multiple high-scoring segments in molecular sequences. Proc Natl Acad Sci USA 90:5873-5877.
12. Kocsis MG, Weselake RJ. 1996. Phosphatidate phosphatases of mammals, yeast, and higher plants. Lipids 31:785-802.
13. Lei KJ, Chen H, Pan CJ, Ward JM, Mosinger B Jr, Lee EJ, Westphal H, Mansfield BC, Chou JY. 1996. Glucose-6-phosphatase dependent substrate trans-port in the glycogen storage disease type-1a mouse. Nat Genet 13:203-209.
14. Lindquist RN, Lynn JL, Lienhard GE. 1973. Possible transition-state analogs for ribonuclease. The complexes of uridine with oxovanadium(IV) ion and vanadium(V) ion. J Am Chem Soc 95:8762-8768.
15. Messerschmidt A, Wever R. 1996. X-ray structure of a vanadium-containing enzyme: Chloroperoxidase from the fungus Curvularia inaequalis. Proc Natl Acad Sci USA 93:392-396.
16. Moolenaar WH. 1995a. Lysophosphatidic acid signalling. Curr Opin Cell Biol 7:203-210.
17. Moolenaar WH. 1995b. Lysophosphatidic acid, a multifunctional phospholipid messenger. J Biol Chem 270:12949-12952.
18. Moolenaar WH, Jalink K, van Corven EJ. 1992. Lysophosphatidic acid: A bioactive phospholipid with growth factor-like properties. Rev Physiol Biochem Pharmacol 119:47-65.
19. Neuwald AF, Liu JS, Lawrence CE. 1995. Gibbs motif sampling: Detection of bacterial outer membrane protein repeats. Protein Sci 4:1618-1632.
20. Neuwald AF, Liu JS, Lipman DJ, Lawrence CE. 1997. Extracting protein alignment models from the sequence database. Nucleic Adds Res 25:1665-1677.
21. Nishizuka Y. 1984. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308:693-698.
22. Ollis DL, Cheah E, Cygler M, Dijksira B, Frolow F Franken SM, Harel M, Remington SJ, Silman I, Schrag J, et al. 1992. The alpha/beta hydrolase fold. Protein Eng 5:197-211.
23. Rost B, Casadio R, Fariselli P, Sander C. 1995. Transmembrane helices predicted at 95% accuracy. Protein Sci 4:521-533.
24. Stankiewicz PJ, Tracey AS, Crans DC. 1995. Inhibition of phosphate-metabolizing enzymes by oxovanadium(V) complexes. Met Ions Biol Syst 31:287-324.
25. Stukey J, Carman GM. 1997. Identification of a novel phosphatase sequence motif. Protein Sci 6:469-472.
26. Thaller MC, Berlutti F, Schippa S, Lombardi G, Rossolini GM. 1994. Characterization and sequence of PhoC, the principal phosphate-irrepressible acid phosphatase of Morganella morganii. Microbiology 140:1341-1350.
27. Tong L, Qian C, Massariol MJ, Bonneau PR, Cordingley MG, Lagace L. 1996. A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease. Nature 383:272-275.
28. Vilter H. 1995. Vanadium-dependent haloperoxidases. Met Ions Biol Syst 31:325-362.
29. Waggoner DW, Gomez-Munoz A, Dewald J, Brindley DN. 1996. Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate. J Biol Chem 271:16506-16509.
30. Zhang N, Zhang J, Purcell KJ, Cheng Y, Howard K. 1997. The Drosophila protein Wunen repels migrating germ cells. Nature 385:64-67.