메뉴 건너뛰기




Volumn 156, Issue 11, 1996, Pages 4083-4091

Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLOROISOCOUMARIN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CONCANAVALIN A; CYCLIC AMP; CYCLOHEXIMIDE; DNA; EMETINE; FAS ANTIGEN; INOSITOL; INOSITOL PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN; PROTEINASE; SERINE PROTEINASE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

EID: 0029967353     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 0029317594 scopus 로고
    • The role of the thymus during T-lymphocyte development in vitro
    • Anderson, G., and E. J. Jenkinson. 1995. The role of the thymus during T-lymphocyte development in vitro. Semin. Immunol. 7:177.
    • (1995) Semin. Immunol. , vol.7 , pp. 177
    • Anderson, G.1    Jenkinson, E.J.2
  • 5
    • 0028859281 scopus 로고
    • Selective requirement for MAP kinase activation in thymocyte differentiation
    • Alberola-Ila, J., K. A. Forbush, R. Seger, E. G. Krebs, and R. M. Perlmutter. 1995. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620.
    • (1995) Nature , vol.373 , pp. 620
    • Alberola-Ila, J.1    Forbush, K.A.2    Seger, R.3    Krebs, E.G.4    Perlmutter, R.M.5
  • 7
    • 0026801981 scopus 로고
    • Effects of the thymic microenvironment on the response of thymocytes to stimulation
    • Moore, N. C., E. J. Jenkinson, and J. J. T. Owen. 1992. Effects of the thymic microenvironment on the response of thymocytes to stimulation. Eur. J. Immunol. 22:2533.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2533
    • Moore, N.C.1    Jenkinson, E.J.2    Owen, J.J.T.3
  • 8
    • 0022631314 scopus 로고
    • Requirements for growth of immature thymocytes from fetal and adult mice in vitro
    • Palacios, R., and H. von Boehmer. 1986. Requirements for growth of immature thymocytes from fetal and adult mice in vitro. Eur. J. Immunol 16:12.
    • (1986) Eur. J. Immunol , vol.16 , pp. 12
    • Palacios, R.1    Von Boehmer, H.2
  • 10
    • 0025908328 scopus 로고
    • T-cell differentiation is influenced by thymic microenvironments
    • van Ewijk, W. 1991. T-cell differentiation is influenced by thymic microenvironments. Annu. Rev. Immunol. 9:591.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 591
    • Van Ewijk, W.1
  • 11
    • 0029067104 scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate hydrolysis accompanies T cell receptor-induced apoptosis of murine thymocytes within the thymus
    • Conroy, L. A., E. J. Jenkinson, J. J. T. Owen, and R. H. Michell. 1995. Phosphatidylinositol 4,5-bisphosphate hydrolysis accompanies T cell receptor-induced apoptosis of murine thymocytes within the thymus. Eur. J. Immunol. 25: 1828.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1828
    • Conroy, L.A.1    Jenkinson, E.J.2    Owen, J.J.T.3    Michell, R.H.4
  • 14
    • 0023394509 scopus 로고
    • Extraction and recovery of inositol phosphates from tissues
    • Wreggett, K. A., L. R. Howe, J. P. Moore, and R. F. Irvine. 1987. Extraction and recovery of inositol phosphates from tissues. Biochem. J. 245:933.
    • (1987) Biochem. J. , vol.245 , pp. 933
    • Wreggett, K.A.1    Howe, L.R.2    Moore, J.P.3    Irvine, R.F.4
  • 16
    • 0028025078 scopus 로고
    • Characteristics of an in vitro system of thymocyte positive selection
    • Anderson, G., J. J. T. Owen, N. C. Moore, and E. J. Jenkinson. 1994. Characteristics of an in vitro system of thymocyte positive selection. J. Immunol. 153: 1915.
    • (1994) J. Immunol. , vol.153 , pp. 1915
    • Anderson, G.1    Owen, J.J.T.2    Moore, N.C.3    Jenkinson, E.J.4
  • 17
    • 0029036650 scopus 로고
    • Expression and function of mouse Fas antigen on immature and mature T cells
    • Nishimura, Y., A. Ishii, Y. Kobayashi, Y. Yamasaki, and S. Yonehara. 1995. Expression and function of mouse Fas antigen on immature and mature T cells. J. Immunol. 154:4395.
    • (1995) J. Immunol. , vol.154 , pp. 4395
    • Nishimura, Y.1    Ishii, A.2    Kobayashi, Y.3    Yamasaki, Y.4    Yonehara, S.5
  • 18
    • 0025024913 scopus 로고
    • Agents that elevate cAMP stimulate DNA fragmentation in thymocytes
    • McConkey, D. J., S. Orrenius, and M. Jondal. 1990. Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J. Immunol. 145:1227.
    • (1990) J. Immunol. , vol.145 , pp. 1227
    • McConkey, D.J.1    Orrenius, S.2    Jondal, M.3
  • 19
    • 0028911483 scopus 로고
    • Upregulation of surface markers on dying thymocytes
    • Kishimoto, H., C. D. Surh, and J. Sprent. 1995. Upregulation of surface markers on dying thymocytes. J. Exp. Med. 181:649.
    • (1995) J. Exp. Med. , vol.181 , pp. 649
    • Kishimoto, H.1    Surh, C.D.2    Sprent, J.3
  • 20
    • 0027972407 scopus 로고
    • The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult αβ thymocytes
    • Andjelic, S., J. Drappa, E. Lacy, K. B. Elkon, and J. Nikolic-Zugic. 1994. The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult αβ thymocytes. Int. Immunol. 6:73.
    • (1994) Int. Immunol. , vol.6 , pp. 73
    • Andjelic, S.1    Drappa, J.2    Lacy, E.3    Elkon, K.B.4    Nikolic-Zugic, J.5
  • 21
    • 0018657126 scopus 로고
    • Identification of β-adrenoceptors during thymocyte ontogeny in mice
    • Singh, U., D. S. Millson, P. A. Smith, and J. J. T. Owen. 1979. Identification of β-adrenoceptors during thymocyte ontogeny in mice. Eur. J. Immunol. 9:31.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 31
    • Singh, U.1    Millson, D.S.2    Smith, P.A.3    Owen, J.J.T.4
  • 22
    • 0029022778 scopus 로고
    • Involvement of cAMP in CD3 T cell receptor complex- and CD2-mediated apoptosis of human thymocytes
    • Mentz, F., M. D. Mossalayi, F. Ouaaz, and P. Debré. 1995. Involvement of cAMP in CD3 T cell receptor complex- and CD2-mediated apoptosis of human thymocytes. Eur. J. Immunol. 25:1798.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1798
    • Mentz, F.1    Mossalayi, M.D.2    Ouaaz, F.3    Debré, P.4
  • 24
    • 0023938335 scopus 로고
    • The adenylate cyclase-cAMP-protein kinase A pathway and the regulation of the immune response
    • Kammer, G. M. 1988. The adenylate cyclase-cAMP-protein kinase A pathway and the regulation of the immune response. Immunol. Today 9:222.
    • (1988) Immunol. Today , vol.9 , pp. 222
    • Kammer, G.M.1
  • 26
    • 0021954564 scopus 로고
    • Neurotransmitters, hormones and cyclic nucleotides in lymphocyte regulation
    • Coffey, R. H., and J. W. Madden. 1985. Neurotransmitters, hormones and cyclic nucleotides in lymphocyte regulation. Fed. Proc. 44:112.
    • (1985) Fed. Proc. , vol.44 , pp. 112
    • Coffey, R.H.1    Madden, J.W.2
  • 27
    • 0023631418 scopus 로고
    • Aluminum fluoride induces phosphatidylinositol turnover, elevation of cytoplasmic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells
    • O'Shea, J. J., K. B. Urdahl, H. T. Luong, T. M. Chused, L. E. Samelson, and R. D. Klausner. 1987. Aluminum fluoride induces phosphatidylinositol turnover, elevation of cytoplasmic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells. J. Immunol. 139:3463.
    • (1987) J. Immunol. , vol.139 , pp. 3463
    • O'Shea, J.J.1    Urdahl, K.B.2    Luong, H.T.3    Chused, T.M.4    Samelson, L.E.5    Klausner, R.D.6
  • 28
    • 0023853005 scopus 로고
    • Cyclic AMP concentration modulates both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes
    • Lerner, A., B. Jacobson, and R. A. Miller. 1988. Cyclic AMP concentration modulates both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes. J. Immunol. 140:936.
    • (1988) J. Immunol. , vol.140 , pp. 936
    • Lerner, A.1    Jacobson, B.2    Miller, R.A.3
  • 29
    • 0024434886 scopus 로고
    • cAMP inhibits the OKT3-induced increase in cytoplasmic free calcium in the Jurkat T cell line: The degree of inhibition correlates inversely with the amount of CD3 binding ligand used
    • Papadogiannakis, N., T. E. Nordstrom, L. C. Andersson, and C. H. J. Wolff. 1989. cAMP inhibits the OKT3-induced increase in cytoplasmic free calcium in the Jurkat T cell line: the degree of inhibition correlates inversely with the amount of CD3 binding ligand used. Eur. J. Immunol. 19:1953.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1953
    • Papadogiannakis, N.1    Nordstrom, T.E.2    Andersson, L.C.3    Wolff, C.H.J.4
  • 30
    • 0026538621 scopus 로고
    • Increased intracellular cAMP inhibits inositol phospholipid hydrolysis by perturbation of the T cell receptor/CD3 complex but not by G-protein stimulation
    • Alava, M. A., K. E. DeBell, A. Conti, T. Hoffman, and E. Bonvini. 1992. Increased intracellular cAMP inhibits inositol phospholipid hydrolysis by perturbation of the T cell receptor/CD3 complex but not by G-protein stimulation. Biochem. J. 284:189.
    • (1992) Biochem. J. , vol.284 , pp. 189
    • Alava, M.A.1    DeBell, K.E.2    Conti, A.3    Hoffman, T.4    Bonvini, E.5
  • 31
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwartzman, R. A., and J. A. Cidlowski. 1993. Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr. Rev. 14:133.
    • (1993) Endocr. Rev. , vol.14 , pp. 133
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 32
    • 0026772442 scopus 로고
    • Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: Lack of evidence for labile repressors
    • Edwards, D. R., and L. C. Mahadevan, L. C. 1992. Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors. EMBO J. 11:2415.
    • (1992) EMBO J. , vol.11 , pp. 2415
    • Edwards, D.R.1    Mahadevan, L.C.2
  • 33
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan, J., S. Shaham, S. Ledoux, H. M. Ellis, and H. R. Horvitz. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641.
    • (1993) Cell , vol.75 , pp. 641
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 34
    • 0029028320 scopus 로고
    • The last cut is the deepest
    • Whyte, M., and G. Evan. 1995. The last cut is the deepest. Nature 356:17.
    • (1995) Nature , vol.356 , pp. 17
    • Whyte, M.1    Evan, G.2
  • 35
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas mediated apoptosis
    • Enari, M., H. Hug, and S. Nagata. 1995. Involvement of an ICE-like protease in Fas mediated apoptosis. Nature 375:78.
    • (1995) Nature , vol.375 , pp. 78
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 38
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau, N., C. J. Sympson, Z. Werb, and M. J. Bissell. 1995. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267:891.
    • (1995) Science , vol.267 , pp. 891
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3    Bissell, M.J.4
  • 40
    • 0028964628 scopus 로고
    • Isolation and partial characterisation of a protease involved in Fas-induced apoptosis
    • Schlegel, J., I. Peters, and S. Orrenius. 1995. Isolation and partial characterisation of a protease involved in Fas-induced apoptosis. FEBS Lett. 364:139.
    • (1995) FEBS Lett. , vol.364 , pp. 139
    • Schlegel, J.1    Peters, I.2    Orrenius, S.3
  • 41
    • 0027658225 scopus 로고
    • Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes
    • Weaver, V. M., B. Lach, P. R. Walker, and M. Sikorska. 1993. Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem. Cell Biol. 71:488.
    • (1993) Biochem. Cell Biol. , vol.71 , pp. 488
    • Weaver, V.M.1    Lach, B.2    Walker, P.R.3    Sikorska, M.4
  • 42
    • 0022271601 scopus 로고
    • Reaction of serine proteases with substituted isocoumarins: Discovery of 3,4-dichlorisocoumarin, a new general mechanism-based serine protease inhibitor
    • Harper, J. W., K. Hemmi, and J. C. Powers. 1985. Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichlorisocoumarin, a new general mechanism-based serine protease inhibitor. Biochemistry 24:1831.
    • (1985) Biochemistry , vol.24 , pp. 1831
    • Harper, J.W.1    Hemmi, K.2    Powers, J.C.3
  • 43
    • 0028409106 scopus 로고
    • Intracellular signals that mediate thymic negative selection
    • Vasquez, N. J., L. P. Kane, and S. M. Hedrick. 1994. Intracellular signals that mediate thymic negative selection. Immunity 1:45.
    • (1994) Immunity , vol.1 , pp. 45
    • Vasquez, N.J.1    Kane, L.P.2    Hedrick, S.M.3
  • 46
    • 0027312867 scopus 로고
    • Restoration of T-cell function in HIV infection by reduction of intracellular cAMP levels with adenosine analogues
    • Hofmann, B., P. Nishanian, T. Nguyen, M. Liu, and J. L. Fahey. 1993. Restoration of T-cell function in HIV infection by reduction of intracellular cAMP levels with adenosine analogues. AIDS 7:659.
    • (1993) AIDS , vol.7 , pp. 659
    • Hofmann, B.1    Nishanian, P.2    Nguyen, T.3    Liu, M.4    Fahey, J.L.5
  • 47
    • 0028168593 scopus 로고
    • Ich-1, an ICE/Ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang, L., M. Miura, L. Bergeron, H. Zhu, and J. Y. Yuan. 1994. Ich-1, an ICE/Ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739.
    • (1994) Cell , vol.78 , pp. 739
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.Y.5
  • 48
    • 0028878468 scopus 로고
    • A preexisting protease is a common effector of thymocyte apoptosis mediated by diverse stimuli
    • Fearnhead, H. O., A. J. Rivett, D. Dinsdale, and G. M. Cohen. 1995. A preexisting protease is a common effector of thymocyte apoptosis mediated by diverse stimuli. FEBS Lett. 357:242.
    • (1995) FEBS Lett. , vol.357 , pp. 242
    • Fearnhead, H.O.1    Rivett, A.J.2    Dinsdale, D.3    Cohen, G.M.4
  • 49
    • 0028537064 scopus 로고
    • The sphingomyelin signal transduction pathway mediates apoptosis for tumour necrosis factor, Fas and ionising radiation
    • Kolesnick, R. N., A. Haimovitz-Friedman, and Z. Fuks. 1994. The sphingomyelin signal transduction pathway mediates apoptosis for tumour necrosis factor, Fas and ionising radiation. Biochem. Cell Biol. 72:471.
    • (1994) Biochem. Cell Biol. , vol.72 , pp. 471
    • Kolesnick, R.N.1    Haimovitz-Friedman, A.2    Fuks, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.