Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways

International Journal of Oncology

Volumn 10, Issue 6, 1997, Pages 1093-1101

  Szabó, Csaba ^a,c   Wong, Hector R ^a   Bauer, Pal I ^b   Kirsten, Eva ^b   O'Connor, Michael ^a   Zingarelli, Basilia ^a   Mendeleyev, Jerome ^b   Haskó, György ^c   Sylvester Vizi, E ^c   Salzman, Andrew L ^a   Kun, Ernest ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b SAN FRANCISCO STATE UNIVERSITY   (United States)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Cyclooxygenase; Endotoxin; MAP kinase; Nitric oxide; Nuclear factor B; Prostaglandins; Septic shock; Superoxide; Tumor necrosis factor

Indexed keywords

5 IODO 6 AMINO 1,2 BENZOPYRONE; 6 OXOPROSTAGLANDIN F1 ALPHA; CYTOKINE; ENZYME INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARCINOGENESIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; IMMUNOBLOTTING; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; SIGNAL TRANSDUCTION;

EID: 0030992125     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.6.1093     Document Type: Article

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