-
1
-
-
0029919273
-
Genetic approaches to adoptive cellular therapy of malignancy
-
Area M.J. Mule J.J. Chang A.E. Genetic approaches to adoptive cellular therapy of malignancy Semin Oncol 23 1996 108 117
-
(1996)
Semin Oncol
, vol.23
, pp. 108-117
-
-
Area, M.J.1
Mule, J.J.2
Chang, A.E.3
-
2
-
-
0027523517
-
A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase
-
Austin E.A. Huber B.E. A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase Mol Pharmacol 43 1993 380 387
-
(1993)
Mol Pharmacol
, vol.43
, pp. 380-387
-
-
Austin, E.A.1
Huber, B.E.2
-
3
-
-
0028323573
-
Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors
-
Barba D. Hardin J. Sadelain M. Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors Proc Natl Acad Sci U S A 91 1994 4348 4352
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4348-4352
-
-
Barba, D.1
Hardin, J.2
Sadelain, M.3
-
4
-
-
0029609678
-
The thymidine kinase/ganciclovir-mediated “suicide” effect is variable in different tumor cells
-
Beck C. Cayeux S. Lupton S.D. The thymidine kinase/ganciclovir-mediated “suicide” effect is variable in different tumor cells Hum Gene Ther 6 1995 1525 1530
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1525-1530
-
-
Beck, C.1
Cayeux, S.2
Lupton, S.D.3
-
5
-
-
0027787053
-
In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy
-
Bi W.L. Parysek L.M. Warnick R. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy Hum Gene Ther 4 1993 725 731
-
(1993)
Hum Gene Ther
, vol.4
, pp. 725-731
-
-
Bi, W.L.1
Parysek, L.M.2
Warnick, R.3
-
6
-
-
0025953066
-
Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells
-
Biron K.K. de Miranda P. Burnette T.C. Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells Antimicrob Agents Chemother 35 1991 2116 2120
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 2116-2120
-
-
Biron, K.K.1
de Miranda, P.2
Burnette, T.C.3
-
7
-
-
0029883624
-
Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy
-
Black M.E. Newcomb T.G. Wilson H.M. Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy Proc Natl Acad Sci U S A 93 1996 3525 3529
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3525-3529
-
-
Black, M.E.1
Newcomb, T.G.2
Wilson, H.M.3
-
8
-
-
0028136584
-
In situ delivery of suicide genes for cancer treatment
-
Blaese R.M. Ishii-Morita H. Mullen C. In situ delivery of suicide genes for cancer treatment Eur J Cancer 30A 1994 1190 1193
-
(1994)
Eur J Cancer
, vol.30A
, pp. 1190-1193
-
-
Blaese, R.M.1
Ishii-Morita, H.2
Mullen, C.3
-
9
-
-
0028919347
-
Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo
-
Bonnekoh B. Greenhalgh D.A. Bundman D.S. Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo J Invest Dermatol 104 1995 313 317
-
(1995)
J Invest Dermatol
, vol.104
, pp. 313-317
-
-
Bonnekoh, B.1
Greenhalgh, D.A.2
Bundman, D.S.3
-
10
-
-
0029946085
-
Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma
-
Bonnekoh B. Greenhalgh D.A. Bundman D.S. Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma J Invest Dermatol 106 1996 1163 1168
-
(1996)
J Invest Dermatol
, vol.106
, pp. 1163-1168
-
-
Bonnekoh, B.1
Greenhalgh, D.A.2
Bundman, D.S.3
-
11
-
-
0028034286
-
Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene
-
Boviatsis E.J. Park J.S. Sena-Esteves M. Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene Cancer Res 54 1994 5745 5751
-
(1994)
Cancer Res
, vol.54
, pp. 5745-5751
-
-
Boviatsis, E.J.1
Park, J.S.2
Sena-Esteves, M.3
-
12
-
-
0029609610
-
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
-
Bridgewater J.A. Springer C.J. Knox R.J. Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954 Eur J Cancer 31A 1995 2362 2370
-
(1995)
Eur J Cancer
, vol.31A
, pp. 2362-2370
-
-
Bridgewater, J.A.1
Springer, C.J.2
Knox, R.J.3
-
13
-
-
0028168775
-
Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors
-
Brody S.L. Jaffe H.A. Han S.K. Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors Hum Gene Ther 5 1994 437 447
-
(1994)
Hum Gene Ther
, vol.5
, pp. 437-447
-
-
Brody, S.L.1
Jaffe, H.A.2
Han, S.K.3
-
14
-
-
0028017985
-
Cancer escape from immune surveillance: How can it be overcome by gene transfer?
-
Bruyns C. Gerard C. Velu T. Cancer escape from immune surveillance: How can it be overcome by gene transfer? Eur J Cancer 30A 1994 1176 1181
-
(1994)
Eur J Cancer
, vol.30A
, pp. 1176-1181
-
-
Bruyns, C.1
Gerard, C.2
Velu, T.3
-
15
-
-
0027291236
-
Regression of established macroscopic liver metastases after in situ transduction of a suicide gene
-
Caruso M. Panis Y. Gagandeep S. Regression of established macroscopic liver metastases after in situ transduction of a suicide gene Proc Natl Acad Sci U S A 90 1993 7024 7028
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7024-7028
-
-
Caruso, M.1
Panis, Y.2
Gagandeep, S.3
-
16
-
-
0028856844
-
Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the “bystander effect”
-
Chen C.Y. Chang Y.N. Ryan P. Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the “bystander effect” Hum Gene Ther 6 1995 1467 1476
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1467-1476
-
-
Chen, C.Y.1
Chang, Y.N.2
Ryan, P.3
-
17
-
-
0028905561
-
Combination gene therapy for liver metastasis of colon carcinoma in vivo
-
Chen S.H. Chen X.H. Wang Y. Combination gene therapy for liver metastasis of colon carcinoma in vivo Proc Natl Acad Sci U S A 92 1995 2577 2581
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 2577-2581
-
-
Chen, S.H.1
Chen, X.H.2
Wang, Y.3
-
18
-
-
0028202066
-
Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
-
Chen S.H. Shine H.D. Goodman J.C. Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo Proc Natl Acad Sci USA 91 1994 3054 3057
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3054-3057
-
-
Chen, S.H.1
Shine, H.D.2
Goodman, J.C.3
-
20
-
-
0029101080
-
Adenovirus-mediated gene therapy for experimental spinal cord tumors: Tumoricidal efficacy and functional outcome
-
Colak A. Goodman J.C. Chen S.H. Adenovirus-mediated gene therapy for experimental spinal cord tumors: Tumoricidal efficacy and functional outcome Brain Res 691 1995 76 82
-
(1995)
Brain Res
, vol.691
, pp. 76-82
-
-
Colak, A.1
Goodman, J.C.2
Chen, S.H.3
-
21
-
-
0029161615
-
The “bystander effect”: Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice
-
Colombo B.M. Benedetti S. Ottolenghi S. The “bystander effect”: Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice Hum Gene Ther 6 1995 763 772
-
(1995)
Hum Gene Ther
, vol.6
, pp. 763-772
-
-
Colombo, B.M.1
Benedetti, S.2
Ottolenghi, S.3
-
22
-
-
0028989592
-
5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory
-
Consalvo M. Mullen C.A. Modesti A. 5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory J Immunol 154 1995 5302 5312
-
(1995)
J Immunol
, vol.154
, pp. 5302-5312
-
-
Consalvo, M.1
Mullen, C.A.2
Modesti, A.3
-
23
-
-
19144364318
-
Curative potential of herpes simplex virus thymidine kinase gene transfer in rats with 9L gliosarcoma
-
Cool V. Pirotte B. Gerard C. Curative potential of herpes simplex virus thymidine kinase gene transfer in rats with 9L gliosarcoma Hum Gene Ther 7 1996 627 635
-
(1996)
Hum Gene Ther
, vol.7
, pp. 627-635
-
-
Cool, V.1
Pirotte, B.2
Gerard, C.3
-
24
-
-
0029869965
-
Noninfectious gene transfer and expression systems for cancer gene therapy
-
Cooper M.J. Noninfectious gene transfer and expression systems for cancer gene therapy Semin Oncol 23 1996 172 187
-
(1996)
Semin Oncol
, vol.23
, pp. 172-187
-
-
Cooper, M.J.1
-
26
-
-
0028875936
-
Transfer of genes to humans: Early lessons and obstacles to success
-
Crystal R.G. Transfer of genes to humans: Early lessons and obstacles to success Science 270 1995 404 410
-
(1995)
Science
, vol.270
, pp. 404-410
-
-
Crystal, R.G.1
-
27
-
-
0026772206
-
In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors [see comments]
-
Culver K.W. Ram Z. Wallbridge S. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors [see comments] Science 256 1992 1550 1552
-
(1992)
Science
, vol.256
, pp. 1550-1552
-
-
Culver, K.W.1
Ram, Z.2
Wallbridge, S.3
-
28
-
-
0025955810
-
Anabolic pathway of 6-methoxypurine arabinoside in cells infected with varicella-zoster virus
-
de Miranda P. Burnette T.C. Biron K.K. Anabolic pathway of 6-methoxypurine arabinoside in cells infected with varicella-zoster virus Antimicrob Agents Chemother 35 1991 2121 2124
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 2121-2124
-
-
de Miranda, P.1
Burnette, T.C.2
Biron, K.K.3
-
30
-
-
0029924404
-
Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models
-
Eastham J.A. Chen S.H. Sehgal I. Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models Hum Gene Ther 7 1996 515 523
-
(1996)
Hum Gene Ther
, vol.7
, pp. 515-523
-
-
Eastham, J.A.1
Chen, S.H.2
Sehgal, I.3
-
31
-
-
0025899005
-
Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene
-
Ezzeddine Z.D. Martuza R.L. Platika D. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene New Biologist 3 1991 608 614
-
(1991)
New Biologist
, vol.3
, pp. 608-614
-
-
Ezzeddine, Z.D.1
Martuza, R.L.2
Platika, D.3
-
32
-
-
0028864786
-
The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro
-
Fick J. Barker F.G.N. Dazin P. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro Proc Natl Acad Sci U S A 92 1995 11071 11075
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11071-11075
-
-
Fick, J.1
Barker, F.G.N.2
Dazin, P.3
-
33
-
-
0029932035
-
Anaerobic bacteria as a delivery system for cancer gene therapy: In vitro activation of 5-fluorocytosine by genetically engineered Clostridia
-
Fox M.E. Lemmon M.J. Mauchline M.L. Anaerobic bacteria as a delivery system for cancer gene therapy: In vitro activation of 5-fluorocytosine by genetically engineered Clostridia Gene Therapy 3 1996 173 178
-
(1996)
Gene Therapy
, vol.3
, pp. 173-178
-
-
Fox, M.E.1
Lemmon, M.J.2
Mauchline, M.L.3
-
35
-
-
0027483695
-
The “bystander effect”: Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman S.M. Abboud C.N. Whartenby K.A. The “bystander effect”: Tumor regression when a fraction of the tumor mass is genetically modified Cancer Res 53 1993 5274 5283
-
(1993)
Cancer Res
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
-
36
-
-
0029111747
-
The treatment of ovarian cancer with a gene modified cancer vaccine: A phase I study
-
Freeman S.M. McCune C. Robinson W. The treatment of ovarian cancer with a gene modified cancer vaccine: A phase I study Hum Gene Ther 6 1995 927 939
-
(1995)
Hum Gene Ther
, vol.6
, pp. 927-939
-
-
Freeman, S.M.1
McCune, C.2
Robinson, W.3
-
37
-
-
0029074452
-
The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells
-
Freeman S.M. Ramesh R. Shastri M. The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells Cancer Lett 92 1995 167 174
-
(1995)
Cancer Lett
, vol.92
, pp. 167-174
-
-
Freeman, S.M.1
Ramesh, R.2
Shastri, M.3
-
39
-
-
0030100158
-
Prodrug-activated gene therapy: Involvement of an immunological component in the “bystander effect”
-
Gagandeep S. Brew R. Green B. Prodrug-activated gene therapy: Involvement of an immunological component in the “bystander effect” Cancer Gene Therapy 3 1996 83 88
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 83-88
-
-
Gagandeep, S.1
Brew, R.2
Green, B.3
-
40
-
-
0029744916
-
Human HLA-specific T-cell clones with stable expression of a suicide gene: A possible tool to drive and control a graft-versus-host-graft-versus-leukemia reaction?
-
Gailot G. Hallet M.M. Gaschet J. Human HLA-specific T-cell clones with stable expression of a suicide gene: A possible tool to drive and control a graft-versus-host-graft-versus-leukemia reaction? Blood 88 1996 1098 1103
-
(1996)
Blood
, vol.88
, pp. 1098-1103
-
-
Gailot, G.1
Hallet, M.M.2
Gaschet, J.3
-
41
-
-
0031039313
-
Monitoring gene therapy with herpes simplex vims thymidine kinase in hepatoma cells: Uptake of specific substrates
-
Haberkorn U. Altmann A. Morr I. Monitoring gene therapy with herpes simplex vims thymidine kinase in hepatoma cells: Uptake of specific substrates J Nucl Med 38 1997 287 294
-
(1997)
J Nucl Med
, vol.38
, pp. 287-294
-
-
Haberkorn, U.1
Altmann, A.2
Morr, I.3
-
42
-
-
0029943796
-
Monitoring gene therapy with cytosine deaminase: In vitro studies using tritiated-5-fluorocytosine
-
Haberkorn U. Oberdörfer F. Gebert J. Monitoring gene therapy with cytosine deaminase: In vitro studies using tritiated-5-fluorocytosine J Nucl Med 37 1996 87 94
-
(1996)
J Nucl Med
, vol.37
, pp. 87-94
-
-
Haberkorn, U.1
Oberdörfer, F.2
Gebert, J.3
-
43
-
-
0031027728
-
Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer
-
Hall S.J. Mutchnik S.E. Chen S.H. Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer Int J Cancer 70 1997 183 187
-
(1997)
Int J Cancer
, vol.70
, pp. 183-187
-
-
Hall, S.J.1
Mutchnik, S.E.2
Chen, S.H.3
-
44
-
-
0029997766
-
Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells
-
Hamel W. Magnelli L. Chiarugi V.P. Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells Cancer Res 56 1996 2697 2702
-
(1996)
Cancer Res
, vol.56
, pp. 2697-2702
-
-
Hamel, W.1
Magnelli, L.2
Chiarugi, V.P.3
-
45
-
-
0028426915
-
Gene therapy for cancer using tumour-specific prodrug activation
-
Harris J.D. Gutierrez A A Hurst H.C. Gene therapy for cancer using tumour-specific prodrug activation Gene Therapy 1 1994 170 175
-
(1994)
Gene Therapy
, vol.1
, pp. 170-175
-
-
Harris, J.D.1
Gutierrez, A A2
Hurst, H.C.3
-
46
-
-
0029986585
-
Tissue specific promoters in targeting systemically delivered gene therapy
-
Hart I.R. Tissue specific promoters in targeting systemically delivered gene therapy Semin Oncol 23 1996 154 158
-
(1996)
Semin Oncol
, vol.23
, pp. 154-158
-
-
Hart, I.R.1
-
47
-
-
0029094952
-
Targeted gene therapy
-
Hart I.R. Vile R.G. Targeted gene therapy Br Med Bull 51 1995 647 655
-
(1995)
Br Med Bull
, vol.51
, pp. 647-655
-
-
Hart, I.R.1
Vile, R.G.2
-
48
-
-
0028937142
-
Retroviral transfer of HSV1-TK gene into human lung cancer cell line
-
Hasegawa Y. Emi N. Shimokata K. Retroviral transfer of HSV1-TK gene into human lung cancer cell line J Mol Med 73 1995 107 112
-
(1995)
J Mol Med
, vol.73
, pp. 107-112
-
-
Hasegawa, Y.1
Emi, N.2
Shimokata, K.3
-
49
-
-
0029923506
-
Comparison of the effects of three different toxin genes and their levels of expression on cell growth and bystander effect in lung adenocarcinoma
-
Hoganson D.K. Batra R.K. Olsen J.C. Comparison of the effects of three different toxin genes and their levels of expression on cell growth and bystander effect in lung adenocarcinoma Cancer Res 56 1996 1315 1323
-
(1996)
Cancer Res
, vol.56
, pp. 1315-1323
-
-
Hoganson, D.K.1
Batra, R.K.2
Olsen, J.C.3
-
50
-
-
0025858452
-
Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: An innovative approach for cancer therapy
-
Huber B.E. Richards C.A. Krenitsky T.A. Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: An innovative approach for cancer therapy Proc Natl Acad Sci U S A 88 1991 8039 8043
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 8039-8043
-
-
Huber, B.E.1
Richards, C.A.2
Krenitsky, T.A.3
-
51
-
-
0027496518
-
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
-
Huber B.E. Austin E.A. Good S.S. In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase Cancer Res 53 1993 4619 4626
-
(1993)
Cancer Res
, vol.53
, pp. 4619-4626
-
-
Huber, B.E.1
Austin, E.A.2
Good, S.S.3
-
52
-
-
0030069289
-
Regulated expression of artificial chimeric genes contained in retroviral vectors: Implications for virus-directed enzyme prodrug therapy (VDEPT) and other gene therapy applications
-
Huber B.E. Richards C.A. Regulated expression of artificial chimeric genes contained in retroviral vectors: Implications for virus-directed enzyme prodrug therapy (VDEPT) and other gene therapy applications Journal of Drug Targeting 3 1996 349 356
-
(1996)
Journal of Drug Targeting
, vol.3
, pp. 349-356
-
-
Huber, B.E.1
Richards, C.A.2
-
53
-
-
0029018605
-
Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter
-
Ido A. Nakata K. Kato Y. Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter Cancer Res 55 1995 3105 3109
-
(1995)
Cancer Res
, vol.55
, pp. 3105-3109
-
-
Ido, A.1
Nakata, K.2
Kato, Y.3
-
54
-
-
0028860038
-
Long-term rat survival after malignant brain tumor regression by retroviral gene therapy
-
Izquierdo M. Cortes M. de Felipe P. Long-term rat survival after malignant brain tumor regression by retroviral gene therapy Gene Therapy 2 1995 66 69
-
(1995)
Gene Therapy
, vol.2
, pp. 66-69
-
-
Izquierdo, M.1
Cortes, M.2
de Felipe, P.3
-
55
-
-
0028016249
-
Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1 [see comments]
-
Jia W.W. McDermott M. Goldie J. Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1 [see comments] J Natl Cancer Inst 86 1994 1209 1215
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1209-1215
-
-
Jia, W.W.1
McDermott, M.2
Goldie, J.3
-
56
-
-
0029559345
-
Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir
-
Joki T. Nakamura M. Ohno T. Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir Hum Gene Ther 6 1995 1507 1513
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1507-1513
-
-
Joki, T.1
Nakamura, M.2
Ohno, T.3
-
57
-
-
0028403237
-
Viral vector systems for gene therapy
-
Jolly D. Viral vector systems for gene therapy Cancer Gene Therapy 1 1994 51 64
-
(1994)
Cancer Gene Therapy
, vol.1
, pp. 51-64
-
-
Jolly, D.1
-
58
-
-
15844416306
-
Gene therapy for alpha-fetoprotein-producing human hepatoma cells by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene
-
Kanai F. Shiratori Y. Yoshida Y. Gene therapy for alpha-fetoprotein-producing human hepatoma cells by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene Hepatology 23 1996 1359 1368
-
(1996)
Hepatology
, vol.23
, pp. 1359-1368
-
-
Kanai, F.1
Shiratori, Y.2
Yoshida, Y.3
-
59
-
-
0031043426
-
In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene
-
Kanai F. Lan K.H. Shiratori Y. In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene Cancer Res 57 1997 461 465
-
(1997)
Cancer Res
, vol.57
, pp. 461-465
-
-
Kanai, F.1
Lan, K.H.2
Shiratori, Y.3
-
60
-
-
0028808656
-
Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression
-
Kaneko S. Hallenbeck P. Kotani T. Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression Cancer Res 55 1995 5283 5287
-
(1995)
Cancer Res
, vol.55
, pp. 5283-5287
-
-
Kaneko, S.1
Hallenbeck, P.2
Kotani, T.3
-
61
-
-
0029112774
-
Gene therapy of hepatoma: Bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir
-
Kaneko Y. Tsukamoto A. Gene therapy of hepatoma: Bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir Cancer Lett 96 1995 105 110
-
(1995)
Cancer Lett
, vol.96
, pp. 105-110
-
-
Kaneko, Y.1
Tsukamoto, A.2
-
62
-
-
0023518829
-
Implantable enzyme capsules for cancer chemotherapy from bakers’ yeast cytosine deaminase immobilized on epoxy-acrylic resin and urethane prepolymer
-
Katsuragi T. Sakai T. Tonomura K. Implantable enzyme capsules for cancer chemotherapy from bakers’ yeast cytosine deaminase immobilized on epoxy-acrylic resin and urethane prepolymer Appl Biochem Biotechnol 16 1987 61 69
-
(1987)
Appl Biochem Biotechnol
, vol.16
, pp. 61-69
-
-
Katsuragi, T.1
Sakai, T.2
Tonomura, K.3
-
63
-
-
0027507937
-
The use of herpes simplex virus vectors for gene therapy in neurological diseases
-
Kennedy P.G. Steiner I. The use of herpes simplex virus vectors for gene therapy in neurological diseases Q J Med 86 1993 697 702
-
(1993)
Q J Med
, vol.86
, pp. 697-702
-
-
Kennedy, P.G.1
Steiner, I.2
-
64
-
-
0028168771
-
Induced expression of the conditionally cytotoxic herpes simplex virus thymidine kinase gene by means of a parvoviral regulatory circuit
-
Koering C.E. Dupressoir T. Plaza S. Induced expression of the conditionally cytotoxic herpes simplex virus thymidine kinase gene by means of a parvoviral regulatory circuit Hum Gene Ther 5 1994 457 463
-
(1994)
Hum Gene Ther
, vol.5
, pp. 457-463
-
-
Koering, C.E.1
Dupressoir, T.2
Plaza, S.3
-
65
-
-
0029818276
-
Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment
-
Kramm C.M. Rainov N.G. Sena-Esteves M. Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment Hum Gene Ther 7 1996 1989 1994
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1989-1994
-
-
Kramm, C.M.1
Rainov, N.G.2
Sena-Esteves, M.3
-
66
-
-
16944364591
-
Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates
-
Kucharczuk J.C. Raper S. Elshami A.A. Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates Hum Gene Ther 7 1996 2225 2233
-
(1996)
Hum Gene Ther
, vol.7
, pp. 2225-2233
-
-
Kucharczuk, J.C.1
Raper, S.2
Elshami, A.A.3
-
67
-
-
0031052384
-
Use of a “replication-restricted” herpes virus to treat experimental human malignant mesothelioma
-
Kucharczuk J.C. Randazzo B. Chang M.Y. Use of a “replication-restricted” herpes virus to treat experimental human malignant mesothelioma Cancer Res 57 1997 466 471
-
(1997)
Cancer Res
, vol.57
, pp. 466-471
-
-
Kucharczuk, J.C.1
Randazzo, B.2
Chang, M.Y.3
-
68
-
-
0030057745
-
Eradication of Myc-overexpressing small cell lung cancer cells transfected with herpes simplex virus thymidine kinase gene containing Myc-Max response elements
-
Kumagai T. Tanio Y. Osaki T. Eradication of Myc-overexpressing small cell lung cancer cells transfected with herpes simplex virus thymidine kinase gene containing Myc-Max response elements Cancer Res 56 1996 354 358
-
(1996)
Cancer Res
, vol.56
, pp. 354-358
-
-
Kumagai, T.1
Tanio, Y.2
Osaki, T.3
-
69
-
-
0028823770
-
Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma
-
Kuriyama S. Nakatani T. Masui K. Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma Hepatology 22 1995 1838 1846
-
(1995)
Hepatology
, vol.22
, pp. 1838-1846
-
-
Kuriyama, S.1
Nakatani, T.2
Masui, K.3
-
70
-
-
0029908175
-
Evaluation of prodrugs ability to induce effective ablation of cells transduced with viral thymidine kinase gene
-
Kuriyama S. Nakatani T. Masui K. Evaluation of prodrugs ability to induce effective ablation of cells transduced with viral thymidine kinase gene Anticancer Res 16 1996 2623 2628
-
(1996)
Anticancer Res
, vol.16
, pp. 2623-2628
-
-
Kuriyama, S.1
Nakatani, T.2
Masui, K.3
-
71
-
-
0030227835
-
Adenoviral-mediated suicide gene therapy for hepatic metastases of breast cancer
-
Kwong Y.L. Chen S.H. Kosai K. Adenoviral-mediated suicide gene therapy for hepatic metastases of breast cancer Cancer Gene Therapy 3 1996 339 344
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 339-344
-
-
Kwong, Y.L.1
Chen, S.H.2
Kosai, K.3
-
72
-
-
0029965148
-
Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy
-
Liang X. Hartikka J. Sukhu L. Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy Gene Therapy 3 1996 350 356
-
(1996)
Gene Therapy
, vol.3
, pp. 350-356
-
-
Liang, X.1
Hartikka, J.2
Sukhu, L.3
-
73
-
-
0029004906
-
Preliminary in vitro efficacy and toxicities studies of the herpes simplex thymidine kinase gene system for the treatment of breast cancer
-
Link CJ Jr Kolb E.M. Muldoon R.R. Preliminary in vitro efficacy and toxicities studies of the herpes simplex thymidine kinase gene system for the treatment of breast cancer Hybridoma 14 1995 143 147
-
(1995)
Hybridoma
, vol.14
, pp. 143-147
-
-
Link, CJ1
Kolb, E.M.2
Muldoon, R.R.3
-
74
-
-
0028607647
-
Delayed morbidity and mortality of albumin/SV40 T-antigen transgenic mice after insertion of an alpha-fetoprotein/herpes virus thymidine kinase transgene and treatment with ganciclovir
-
Macri P. Gordon J.W. Delayed morbidity and mortality of albumin/SV40 T-antigen transgenic mice after insertion of an alpha-fetoprotein/herpes virus thymidine kinase transgene and treatment with ganciclovir Hum Gene Ther 5 1994 175 182
-
(1994)
Hum Gene Ther
, vol.5
, pp. 175-182
-
-
Macri, P.1
Gordon, J.W.2
-
75
-
-
0028127077
-
Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir
-
Manome Y. Abe M. Hagen M.F. Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir Cancer Res 54 1994 5408 5413
-
(1994)
Cancer Res
, vol.54
, pp. 5408-5413
-
-
Manome, Y.1
Abe, M.2
Hagen, M.F.3
-
76
-
-
0029991063
-
Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: Long-term followup by magnetic resonance imaging
-
Maron A. Gustin T. Le Roux A. Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: Long-term followup by magnetic resonance imaging Gene Therapy 3 1996 315 322
-
(1996)
Gene Therapy
, vol.3
, pp. 315-322
-
-
Maron, A.1
Gustin, T.2
Le Roux, A.3
-
77
-
-
0029996360
-
Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins
-
Mesnil M. Piccoli C. Tiraby G. Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins Proc Natl Acad Sci U S A 93 1996 1831 1835
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1831-1835
-
-
Mesnil, M.1
Piccoli, C.2
Tiraby, G.3
-
78
-
-
0028990363
-
Site-directed mutagenesis of herpes simplex virus type 1 thymidine kinase opposes the importance of amino acid positions 251, 321 and 348 for selective recognition of substrate analogs
-
Michael M. Fetzer I. Folkers G. Site-directed mutagenesis of herpes simplex virus type 1 thymidine kinase opposes the importance of amino acid positions 251, 321 and 348 for selective recognition of substrate analogs Biochem Biophys Res Commun 209 1995 966 973
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 966-973
-
-
Michael, M.1
Fetzer, I.2
Folkers, G.3
-
79
-
-
0028946357
-
Targeted vectors for gene therapy
-
Miller N. Vile R. Targeted vectors for gene therapy FASEB J 9 1995 190 199
-
(1995)
FASEB J
, vol.9
, pp. 190-199
-
-
Miller, N.1
Vile, R.2
-
80
-
-
0028108669
-
Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant
-
Mineta T. Rabkin S.D. Martuza R.L. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant Cancer Res 54 1994 3963 3966
-
(1994)
Cancer Res
, vol.54
, pp. 3963-3966
-
-
Mineta, T.1
Rabkin, S.D.2
Martuza, R.L.3
-
81
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T. Rabkin S.D. Yazaki T. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas Nature Medicine 1 1995 938 943
-
(1995)
Nature Medicine
, vol.1
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
-
82
-
-
0025291567
-
Mosaicism induced by gene insertion as a means of improving chemotherapeutic selectivity
-
Moolten F.L. Mosaicism induced by gene insertion as a means of improving chemotherapeutic selectivity Crit Rev Immunol 10 1990 203 233
-
(1990)
Crit Rev Immunol
, vol.10
, pp. 203-233
-
-
Moolten, F.L.1
-
83
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten F.L. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy Cancer Res 46 1986 5276 5281
-
(1986)
Cancer Res
, vol.46
, pp. 5276-5281
-
-
Moolten, F.L.1
-
84
-
-
0025241769
-
Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
-
Moolten F.L. Wells J.M. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors J Natl Cancer Inst 82 1990 297 300
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 297-300
-
-
Moolten, F.L.1
Wells, J.M.2
-
85
-
-
0030036528
-
Transduction of the herpes thymidine kinase gene into premalignant murine mammary epithelial cells renders subsequent breast cancers responsive to ganciclovir therapy
-
Moolten F.L. Vonderhaar B.K. Mroz P.J. Transduction of the herpes thymidine kinase gene into premalignant murine mammary epithelial cells renders subsequent breast cancers responsive to ganciclovir therapy Hum Gene Ther 7 1996 1197 1204
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1197-1204
-
-
Moolten, F.L.1
Vonderhaar, B.K.2
Mroz, P.J.3
-
86
-
-
0025444099
-
Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene
-
Moolten F.L. Wells J.M. Heyman R.A. Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene Hum Gene Ther 1 1990 125 134
-
(1990)
Hum Gene Ther
, vol.1
, pp. 125-134
-
-
Moolten, F.L.1
Wells, J.M.2
Heyman, R.A.3
-
87
-
-
0027738391
-
Retrovirally transduced Escherichia coli gpt genes combine selectability with chemosensitivity capable of mediating tumor eradication
-
Mroz P.J. Moolten F.L. Retrovirally transduced Escherichia coli gpt genes combine selectability with chemosensitivity capable of mediating tumor eradication Hum Gene Ther 4 1993 589 595
-
(1993)
Hum Gene Ther
, vol.4
, pp. 589-595
-
-
Mroz, P.J.1
Moolten, F.L.2
-
88
-
-
0026599586
-
Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
-
Mullen C.A. Kilstmp M. Blaese R.M. Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system Proc Natl Acad Sci U S A 89 1992 33 37
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 33-37
-
-
Mullen, C.A.1
Kilstmp, M.2
Blaese, R.M.3
-
89
-
-
0028297316
-
Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
-
Mullen C.A. Coale M.M. Lowe R. Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor Cancer Res 54 1994 1503 1506
-
(1994)
Cancer Res
, vol.54
, pp. 1503-1506
-
-
Mullen, C.A.1
Coale, M.M.2
Lowe, R.3
-
90
-
-
0029878461
-
Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes
-
Mullen C.A. Petropoulos D. Lowe R.M. Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes Cancer Res 56 1996 1361 1366
-
(1996)
Cancer Res
, vol.56
, pp. 1361-1366
-
-
Mullen, C.A.1
Petropoulos, D.2
Lowe, R.M.3
-
91
-
-
0031049485
-
Thymidine kinase (TK) gene-transduced human lymphocytes can be highly purified, remain fully functional, and are killed efficiently with ganciclovir
-
Munshi N.C. Govindarajan R. Drake R. Thymidine kinase (TK) gene-transduced human lymphocytes can be highly purified, remain fully functional, and are killed efficiently with ganciclovir Blood 89 1997 1334 1340
-
(1997)
Blood
, vol.89
, pp. 1334-1340
-
-
Munshi, N.C.1
Govindarajan, R.2
Drake, R.3
-
92
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
Nabel G.J. Nabel E.G. Yang Z.Y. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans Proc Natl Acad Sci U S A 90 1993 11307 11311
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 11307-11311
-
-
Nabel, G.J.1
Nabel, E.G.2
Yang, Z.Y.3
-
93
-
-
0029554993
-
Direct gene transfer for treatment of human cancer
-
Nabel G.J. Yang Z.Y. Nabel E.G. Direct gene transfer for treatment of human cancer Ann NY Acad Sci 772 1995 227 231
-
(1995)
Ann NY Acad Sci
, vol.772
, pp. 227-231
-
-
Nabel, G.J.1
Yang, Z.Y.2
Nabel, E.G.3
-
94
-
-
0029952922
-
Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging
-
Namba H. Iwadate Y. Tagawa M. Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging Hum Gene Ther 7 1996 1847 1852
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1847-1852
-
-
Namba, H.1
Iwadate, Y.2
Tagawa, M.3
-
95
-
-
0028907668
-
Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model
-
O’Malley BW Jr Chen S.H. Schwartz M.R. Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model Cancer Res 55 1995 1080 1085
-
(1995)
Cancer Res
, vol.55
, pp. 1080-1085
-
-
O’Malley, BW1
Chen, S.H.2
Schwartz, M.R.3
-
96
-
-
0029870613
-
Combination gene therapy for oral cancer in a murine model
-
O’Malley B.W. Cope K.A. Chen S.H. Combination gene therapy for oral cancer in a murine model Cancer Res 56 1996 1737 1741
-
(1996)
Cancer Res
, vol.56
, pp. 1737-1741
-
-
O’Malley, B.W.1
Cope, K.A.2
Chen, S.H.3
-
97
-
-
0030460621
-
Gene therapy for adult T cell leukemia using human immunodeficiency virus vector carrying the thymidine kinase gene of herpes simplex virus type 1
-
Obaru K. Fujii S. Matsushita S. Gene therapy for adult T cell leukemia using human immunodeficiency virus vector carrying the thymidine kinase gene of herpes simplex virus type 1 Hum Gene Ther 7 1996 2203 2208
-
(1996)
Hum Gene Ther
, vol.7
, pp. 2203-2208
-
-
Obaru, K.1
Fujii, S.2
Matsushita, S.3
-
98
-
-
0027548077
-
Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir
-
Oldfield E.H. Ram Z. Culver K.W. Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir Hum Gene Ther 4 1993 39 69
-
(1993)
Hum Gene Ther
, vol.4
, pp. 39-69
-
-
Oldfield, E.H.1
Ram, Z.2
Culver, K.W.3
-
99
-
-
0029743162
-
Use of von Willebrand factor promoter to transduce suicidal gene to human endothelial cells, HUVEC
-
Ozaki K. Yoshida T. Ide H. Use of von Willebrand factor promoter to transduce suicidal gene to human endothelial cells, HUVEC Hum Gene Ther 7 1996 1483 1490
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1483-1490
-
-
Ozaki, K.1
Yoshida, T.2
Ide, H.3
-
101
-
-
0029737399
-
Anti-tumor immunity is involved in the thymidine kinase-mediated killing of tumors induced by activated Ki-ras(G12V
-
Pavlovic J. Nawrath M. Tu R. Anti-tumor immunity is involved in the thymidine kinase-mediated killing of tumors induced by activated Ki-ras(G12V Gene Therapy 3 1996 635 643
-
(1996)
Gene Therapy
, vol.3
, pp. 635-643
-
-
Pavlovic, J.1
Nawrath, M.2
Tu, R.3
-
102
-
-
0027973509
-
Adenovirus-mediated gene therapy of experimental gliomas
-
Perez-Cruet M.J. Trask T.W. Chen S.H. Adenovirus-mediated gene therapy of experimental gliomas J Neurosci Res 39 1994 506 511
-
(1994)
J Neurosci Res
, vol.39
, pp. 506-511
-
-
Perez-Cruet, M.J.1
Trask, T.W.2
Chen, S.H.3
-
103
-
-
0029131940
-
Induction of sensitivity to ganciclovir in human hepatocellular carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase
-
Qian C. Bilbao R. Bruna O. Induction of sensitivity to ganciclovir in human hepatocellular carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase Hepatology 22 1995 118 123
-
(1995)
Hepatology
, vol.22
, pp. 118-123
-
-
Qian, C.1
Bilbao, R.2
Bruna, O.3
-
104
-
-
0030100318
-
Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ ganciclovir paradigm
-
Rainov N.G. Kramm C.M. Aboody-Guterman K. Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ ganciclovir paradigm Cancer Gene Therapy 3 1996 99 106
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 99-106
-
-
Rainov, N.G.1
Kramm, C.M.2
Aboody-Guterman, K.3
-
105
-
-
0027531548
-
In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats [see comments]
-
Ram Z. Culver K.W. Walbridge S. In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats [see comments] Cancer Res 53 1993 83 88
-
(1993)
Cancer Res
, vol.53
, pp. 83-88
-
-
Ram, Z.1
Culver, K.W.2
Walbridge, S.3
-
106
-
-
0027317796
-
Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors
-
Ram Z. Culver K.W. Walbridge S. Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors J Neurosurg 79 1993 400 407
-
(1993)
J Neurosurg
, vol.79
, pp. 400-407
-
-
Ram, Z.1
Culver, K.W.2
Walbridge, S.3
-
107
-
-
0028071271
-
The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats
-
Ram Z. Walbridge S. Shawker T. The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats J Neurosurg 81 1994 256 260
-
(1994)
J Neurosurg
, vol.81
, pp. 256-260
-
-
Ram, Z.1
Walbridge, S.2
Shawker, T.3
-
108
-
-
0027016116
-
Evolutionary aspects of human cancer
-
Ramel C. Evolutionary aspects of human cancer Pharmacogenetics 2 1992 344 349
-
(1992)
Pharmacogenetics
, vol.2
, pp. 344-349
-
-
Ramel, C.1
-
109
-
-
0030007803
-
In vivo analysis of the “bystander effect”: A cytokine cascade
-
Ramesh R. Marrogi A.J. Munshi A. In vivo analysis of the “bystander effect”: A cytokine cascade Exp Hematol 24 1996 829 838
-
(1996)
Exp Hematol
, vol.24
, pp. 829-838
-
-
Ramesh, R.1
Marrogi, A.J.2
Munshi, A.3
-
110
-
-
0030587476
-
Herpes simplex 1716—an ICP 34.5 mutant—is severely replication restricted in human skin xenografts in vivo
-
Randazzo B.P. Kucharczuk J.C. Litzky L.A. Herpes simplex 1716—an ICP 34.5 mutant—is severely replication restricted in human skin xenografts in vivo Virology 223 1996 392 395
-
(1996)
Virology
, vol.223
, pp. 392-395
-
-
Randazzo, B.P.1
Kucharczuk, J.C.2
Litzky, L.A.3
-
111
-
-
0028984807
-
Transcriptional regulatory sequences of carcinoembryonic antigen: Identification and use with cytosine deaminase for tumor-specific gene therapy
-
Richards C.A. Austin E.A. Huber B.E. Transcriptional regulatory sequences of carcinoembryonic antigen: Identification and use with cytosine deaminase for tumor-specific gene therapy Hum Gene Ther 6 1995 881 893
-
(1995)
Hum Gene Ther
, vol.6
, pp. 881-893
-
-
Richards, C.A.1
Austin, E.A.2
Huber, B.E.3
-
112
-
-
0030459592
-
Suicide gene expression induced in tumour cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter
-
Ring C.J. Harris J.D. Hurst H.C. Suicide gene expression induced in tumour cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter Gene Therapy 3 1996 1094 1103
-
(1996)
Gene Therapy
, vol.3
, pp. 1094-1103
-
-
Ring, C.J.1
Harris, J.D.2
Hurst, H.C.3
-
113
-
-
0030467588
-
Killing Epstein-Barr virus-positive B lymphocytes by gene therapy: Comparing the efficacy of cytosine deaminase and herpes simplex virus thymidine kinase
-
Rogers R.P. Ge J.Q. Holley-Guthrie E. Killing Epstein-Barr virus-positive B lymphocytes by gene therapy: Comparing the efficacy of cytosine deaminase and herpes simplex virus thymidine kinase Hum Gene Ther 7 1996 2235 2245
-
(1996)
Hum Gene Ther
, vol.7
, pp. 2235-2245
-
-
Rogers, R.P.1
Ge, J.Q.2
Holley-Guthrie, E.3
-
114
-
-
0031024794
-
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity
-
Rogulski K.R. Kim J.H. Kim S.H. Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity Hum Gene Ther 8 1997 73 85
-
(1997)
Hum Gene Ther
, vol.8
, pp. 73-85
-
-
Rogulski, K.R.1
Kim, J.H.2
Kim, S.H.3
-
115
-
-
0024988334
-
Gene transfer into humans: Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction [see comments]
-
Rosenberg S.A. Aebersold P. Cornetta K. Gene transfer into humans: Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction [see comments] N Engl J Med 323 1990 570 578
-
(1990)
N Engl J Med
, vol.323
, pp. 570-578
-
-
Rosenberg, S.A.1
Aebersold, P.2
Cornetta, K.3
-
116
-
-
0029658585
-
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma
-
Rosenfeld M.E. Wang M. Siegal G.P. Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma Journal of Molecular Medicine 74 1996 455 462
-
(1996)
Journal of Molecular Medicine
, vol.74
, pp. 455-462
-
-
Rosenfeld, M.E.1
Wang, M.2
Siegal, G.P.3
-
117
-
-
0029799638
-
Gene therapy in the United States: A five-year status report
-
Ross G. Erickson R. Knorr D. Gene therapy in the United States: A five-year status report Hum Gene Ther 7 1996 1781 1790
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1781-1790
-
-
Ross, G.1
Erickson, R.2
Knorr, D.3
-
118
-
-
0031025998
-
Gene therapy for cancer: What have we done and where are we going?
-
Roth J.A. Cristiano R.J. Gene therapy for cancer: What have we done and where are we going? J Natl Cancer Inst 89 1997 21 39
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 21-39
-
-
Roth, J.A.1
Cristiano, R.J.2
-
119
-
-
0030052275
-
Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer
-
Rowley S. Lindauer M. Gebert J.F. Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer J Surg Oncol 61 1996 42 48
-
(1996)
J Surg Oncol
, vol.61
, pp. 42-48
-
-
Rowley, S.1
Lindauer, M.2
Gebert, J.F.3
-
120
-
-
0028074962
-
Replicating vectors for gene therapy of cancer: Risks, limitations and prospects
-
Russell S.J. Replicating vectors for gene therapy of cancer: Risks, limitations and prospects Eur J Cancer 30A 1994 1165 1171
-
(1994)
Eur J Cancer
, vol.30A
, pp. 1165-1171
-
-
Russell, S.J.1
-
121
-
-
0027312542
-
Targeting of retroviral vectors for gene therapy
-
Salmons B. Gunzburg W.H. Targeting of retroviral vectors for gene therapy Hum Gene Ther 4 1993 129 141
-
(1993)
Hum Gene Ther
, vol.4
, pp. 129-141
-
-
Salmons, B.1
Gunzburg, W.H.2
-
122
-
-
0029872325
-
Parvoviral vectors for the gene therapy of cancer
-
Shaughnessy E. Lu D. Chatterjee S. Parvoviral vectors for the gene therapy of cancer Semin Oncol 23 1996 159 171
-
(1996)
Semin Oncol
, vol.23
, pp. 159-171
-
-
Shaughnessy, E.1
Lu, D.2
Chatterjee, S.3
-
123
-
-
0029934048
-
Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector
-
Smith T.A. White B.D. Gardner J.M. Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector Gene Therapy 3 1996 496 502
-
(1996)
Gene Therapy
, vol.3
, pp. 496-502
-
-
Smith, T.A.1
White, B.D.2
Gardner, J.M.3
-
124
-
-
0028348372
-
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: An effective in vitro drug sensitization system
-
Smythe W.R. Hwang H.C. Amin K.M. Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: An effective in vitro drug sensitization system Cancer Res 54 1994 2055 2059
-
(1994)
Cancer Res
, vol.54
, pp. 2055-2059
-
-
Smythe, W.R.1
Hwang, H.C.2
Amin, K.M.3
-
125
-
-
0028907485
-
Differential sensitivity of thoracic malignant tumors to adenovirus-mediated drug sensitization gene therapy
-
Smythe W.R. Hwang H.C. Elshami A A Differential sensitivity of thoracic malignant tumors to adenovirus-mediated drug sensitization gene therapy J Thorac Cardiovasc Surg 109 1995 626 630
-
(1995)
J Thorac Cardiovasc Surg
, vol.109
, pp. 626-630
-
-
Smythe, W.R.1
Hwang, H.C.2
Elshami, A A3
-
126
-
-
0029076201
-
Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene
-
Smythe W.R. Hwang H.C. Elshami A A Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene Ann Surg 222 1995 78 86
-
(1995)
Ann Surg
, vol.222
, pp. 78-86
-
-
Smythe, W.R.1
Hwang, H.C.2
Elshami, A A3
-
127
-
-
0028340984
-
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma [see comments]
-
Smythe W.R. Kaiser L.R. Hwang H.C. Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma [see comments] Ann Thorac Surg 57 1994 1395 1401
-
(1994)
Ann Thorac Surg
, vol.57
, pp. 1395-1401
-
-
Smythe, W.R.1
Kaiser, L.R.2
Hwang, H.C.3
-
128
-
-
85119809635
-
-
Sterman DH, Treat J, Litzky LA, et al: Adenoviral-mediated herpes simplex virus thymidine kinase gene delivery in patients with localized malignancy: Results of a phase I trial in malignant mesothelioma. Human Gene Therapy, in press
-
-
-
-
129
-
-
0029921190
-
Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene
-
Su H. Chang J.C. Xu S.M. Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene Hum Gene Ther 7 1996 463 470
-
(1996)
Hum Gene Ther
, vol.7
, pp. 463-470
-
-
Su, H.1
Chang, J.C.2
Xu, S.M.3
-
130
-
-
0031024320
-
Adenovirus-mediated suicide gene therapy for experimental bladder cancer
-
Sutton M.A. Berkman S.A. Chen S.H. Adenovirus-mediated suicide gene therapy for experimental bladder cancer Urology 49 1997 173 180
-
(1997)
Urology
, vol.49
, pp. 173-180
-
-
Sutton, M.A.1
Berkman, S.A.2
Chen, S.H.3
-
131
-
-
0030919225
-
Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes
-
Takahashi T. Namiki Y. Ohno T. Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes Hum Gene Ther 8 1997 827 833
-
(1997)
Hum Gene Ther
, vol.8
, pp. 827-833
-
-
Takahashi, T.1
Namiki, Y.2
Ohno, T.3
-
132
-
-
0027217637
-
An experimental model of retrovirus gene therapy for malignant brain tumors
-
Takamiya Y. Short M.P. Moolten F.L. An experimental model of retrovirus gene therapy for malignant brain tumors J Neurosurg 79 1993 104 110
-
(1993)
J Neurosurg
, vol.79
, pp. 104-110
-
-
Takamiya, Y.1
Short, M.P.2
Moolten, F.L.3
-
133
-
-
0029945087
-
Therapeutic potency of transduction with herpes simplex virus thymidine kinase gene against multidrug resistant mouse leukemia cells
-
Takenaga K. Tagawa M. Sakiyama S. Therapeutic potency of transduction with herpes simplex virus thymidine kinase gene against multidrug resistant mouse leukemia cells Anticancer Res 16 1996 681 685
-
(1996)
Anticancer Res
, vol.16
, pp. 681-685
-
-
Takenaga, K.1
Tagawa, M.2
Sakiyama, S.3
-
134
-
-
0030137379
-
Escherichia coli gpt gene sensitizes rat glioma cells to killing by 6-thioxanthine or 6-thioguanine
-
Tamiya T. Ono Y. Wei M.X. Escherichia coli gpt gene sensitizes rat glioma cells to killing by 6-thioxanthine or 6-thioguanine Cancer Gene Therapy 3 1996 155 162
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 155-162
-
-
Tamiya, T.1
Ono, Y.2
Wei, M.X.3
-
135
-
-
0030939479
-
Targeted killing of migrating glioma cells by injection of HTK-modified glioma cells
-
Tamura M. Shimizu K. Masanobu Y. Targeted killing of migrating glioma cells by injection of HTK-modified glioma cells Hum Gene Ther 8 1997 381 391
-
(1997)
Hum Gene Ther
, vol.8
, pp. 381-391
-
-
Tamura, M.1
Shimizu, K.2
Masanobu, Y.3
-
136
-
-
0029927495
-
Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro
-
Tanaka T. Kanai F. Okabe S. Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro Cancer Res 56 1996 1341 1345
-
(1996)
Cancer Res
, vol.56
, pp. 1341-1345
-
-
Tanaka, T.1
Kanai, F.2
Okabe, S.3
-
137
-
-
0027997532
-
Use of suicide genes in gene therapy
-
Tiberghien P. Use of suicide genes in gene therapy J Leukoc Biol 56 1994 203 209
-
(1994)
J Leukoc Biol
, vol.56
, pp. 203-209
-
-
Tiberghien, P.1
-
138
-
-
0029866724
-
In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration
-
Tong X.W. Block A. Chen S.H. In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration Gynecol Oncol 61 1996 175 179
-
(1996)
Gynecol Oncol
, vol.61
, pp. 175-179
-
-
Tong, X.W.1
Block, A.2
Chen, S.H.3
-
139
-
-
0028800141
-
Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/ prodrug systems in a human colorectal carcinoma cell line
-
Trinh Q.T. Austin E.A. Murray D.M. Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/ prodrug systems in a human colorectal carcinoma cell line Cancer Res 55 1995 4808 4812
-
(1995)
Cancer Res
, vol.55
, pp. 4808-4812
-
-
Trinh, Q.T.1
Austin, E.A.2
Murray, D.M.3
-
140
-
-
0028115073
-
Retrovirus-mediated gene transfer in cancer therapy
-
Uckert W. Walther W. Retrovirus-mediated gene transfer in cancer therapy Pharmacol Ther 63 1994 323 347
-
(1994)
Pharmacol Ther
, vol.63
, pp. 323-347
-
-
Uckert, W.1
Walther, W.2
-
141
-
-
0027255414
-
Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA
-
Vile R.G. Hart I.R. Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA Cancer Res 53 1993 3860 3864
-
(1993)
Cancer Res
, vol.53
, pp. 3860-3864
-
-
Vile, R.G.1
Hart, I.R.2
-
142
-
-
0028385731
-
Gene transfer technologies for the gene therapy of cancer
-
Vile R. Russell S.J. Gene transfer technologies for the gene therapy of cancer Gene Therapy 1 1994 88 98
-
(1994)
Gene Therapy
, vol.1
, pp. 88-98
-
-
Vile, R.1
Russell, S.J.2
-
143
-
-
0028075655
-
Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
-
Vile R.G. Nelson J.A. Castleden S. Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component Cancer Res 54 1994 6228 6234
-
(1994)
Cancer Res
, vol.54
, pp. 6228-6234
-
-
Vile, R.G.1
Nelson, J.A.2
Castleden, S.3
-
144
-
-
19144362837
-
Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumors
-
Vincent A.J. Vogels R. Someren G.V. Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumors Hum Gene Ther 7 1996 197 205
-
(1996)
Hum Gene Ther
, vol.7
, pp. 197-205
-
-
Vincent, A.J.1
Vogels, R.2
Someren, G.V.3
-
145
-
-
0029977047
-
Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis
-
Wallace H. Clarke A.R. Harrison D.J. Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis Oncogene 13 1996 55 61
-
(1996)
Oncogene
, vol.13
, pp. 55-61
-
-
Wallace, H.1
Clarke, A.R.2
Harrison, D.J.3
-
146
-
-
0028335819
-
Intratumoral generation of 5-fluorouracil mediated by an antibody-cytosine deaminase conjugate in combination with 5-fluorocytosine
-
Wallace P.M. MacMaster J.F. Smith V.F. Intratumoral generation of 5-fluorouracil mediated by an antibody-cytosine deaminase conjugate in combination with 5-fluorocytosine Cancer Res 54 1994 2719 2723
-
(1994)
Cancer Res
, vol.54
, pp. 2719-2723
-
-
Wallace, P.M.1
MacMaster, J.F.2
Smith, V.F.3
-
147
-
-
0000314691
-
Herpes simplex virus
-
Whitley R.J. Herpes simplex virus Fields B.N. Knipe D.M. Virology 1990 Raven New York 1843 1887
-
(1990)
, pp. 1843-1887
-
-
Whitley, R.J.1
-
148
-
-
0029794390
-
Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir
-
Yang L. Hwang R. Pandit L. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir Ann Surg 224 1996 405 414
-
(1996)
Ann Surg
, vol.224
, pp. 405-414
-
-
Yang, L.1
Hwang, R.2
Pandit, L.3
-
149
-
-
0028822061
-
Treatment of human malignant meningiomas by G207 a replication-competent multimutated herpes simplex virus 1
-
Yazaki T. Manz H.J. Rabkin S.D. Treatment of human malignant meningiomas by G207 a replication-competent multimutated herpes simplex virus 1 Cancer Res 55 1995 4752 4756
-
(1995)
Cancer Res
, vol.55
, pp. 4752-4756
-
-
Yazaki, T.1
Manz, H.J.2
Rabkin, S.D.3
-
150
-
-
0030054785
-
Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer
-
Yee D. McGuire S.E. Brunner N. Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer Hum Gene Ther 7 1996 1251 1257
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1251-1257
-
-
Yee, D.1
McGuire, S.E.2
Brunner, N.3
-
151
-
-
0028951470
-
Retrovirally transmitted gene therapy for gastric carcinoma using herpes simplex virus thymidine kinase gene
-
Yoshida K. Kawami H. Yamaguchi Y. Retrovirally transmitted gene therapy for gastric carcinoma using herpes simplex virus thymidine kinase gene Cancer 75 1995 1467 1471 6 suppl
-
(1995)
Cancer
, vol.75
, pp. 1467-1471
-
-
Yoshida, K.1
Kawami, H.2
Yamaguchi, Y.3
-
152
-
-
0030277187
-
Liposomal delivery of the herpes simplex virus thymidine kinase gene in glioma: Improvement of cell sensitization to ganciclovir
-
Zerrouqi A. Rixe O. Ghoumari A.M. Liposomal delivery of the herpes simplex virus thymidine kinase gene in glioma: Improvement of cell sensitization to ganciclovir Cancer Gene Therapy 3 1996 385 392
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 385-392
-
-
Zerrouqi, A.1
Rixe, O.2
Ghoumari, A.M.3
-
153
-
-
0030956975
-
Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo
-
Zhang L. Wikenheiser K.A. Whitsett J.A. Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo Hum Gene Ther 8 1997 563 574
-
(1997)
Hum Gene Ther
, vol.8
, pp. 563-574
-
-
Zhang, L.1
Wikenheiser, K.A.2
Whitsett, J.A.3
-
154
-
-
0027420445
-
The gene therapy of cancer: Transgenic immunotherapy
-
Zwiebel J.A. Su N. MacPherson A. The gene therapy of cancer: Transgenic immunotherapy Semin Hematol 30 1993 119 128 4 suppl 4
-
(1993)
Semin Hematol
, vol.30
, pp. 119-128
-
-
Zwiebel, J.A.1
Su, N.2
MacPherson, A.3
|