Anaerobic bacteria as a delivery system for cancer gene therapy: In vitro activation of 5-fluorocytosine by genetically engineered clostridia

Gene Therapy

Volumn 3, Issue 2, 1996, Pages 173-178

  Fox, M E ^a   Lemmon, M J ^a   Mauchline, M L ^b   Davis, T O ^b   Giaccia, A J ^a   Minton, N P ^b   Brown, J M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Anaerobe; Clostridia; Cytosine deaminase; Enzyme prodrug therapy; Gene therapy

Indexed keywords

CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL; PRODRUG;

ANAEROBIC BACTERIUM; ANIMAL CELL; ARTICLE; CANCER THERAPY; CARCINOMA CELL; CLOSTRIDIUM; CONTROLLED STUDY; DRUG ACTIVATION; DRUG SENSITIVITY; EMBRYO; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE TARGETING; GENE THERAPY; GENETIC ENGINEERING; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BASE SEQUENCE; CARCINOMA; CELL SURVIVAL; CLONING, MOLECULAR; CLOSTRIDIUM; CYTOSINE DEAMINASE; ESCHERICHIA COLI; FLUCYTOSINE; FLUOROURACIL; GENE THERAPY; GENE TRANSFER TECHNIQUES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; NUCLEOSIDE DEAMINASES; PRODRUGS; TRANSFORMATION, BACTERIAL; TUMOR CELLS, CULTURED;

ANIMALIA; BACTERIA (MICROORGANISMS); CLOSTRIDIA; CLOSTRIDIUM; ESCHERICHIA COLI; MURINAE;

EID: 0029932035     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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