메뉴 건너뛰기




Volumn 61, Issue 1, 1996, Pages 42-48

Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer

Author keywords

colorectal cancer; cytosine deaminase; in situ gene therapy

Indexed keywords

CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL;

EID: 0030052275     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199601)61:1<42::AID-JSO10>3.0.CO;2-Z     Document Type: Article
Times cited : (27)

References (33)
  • 3
    • 0024535825 scopus 로고
    • Hepatic resection of metastases from colorectal carcinoma: Morbidity, mortality, and pattern of recurrence
    • Holm A, Bradley E, Aldrete JS: Hepatic resection of metastases from colorectal carcinoma: Morbidity, mortality, and pattern of recurrence. Ann Surg 209:428-434, 1989.
    • (1989) Ann Surg , vol.209 , pp. 428-434
    • Holm, A.1    Bradley, E.2    Aldrete, J.S.3
  • 4
    • 0025243470 scopus 로고
    • Hepatic metastases from colorectal carcinoma: Impact of surgical resection on the natural history
    • Scheele J, Stangl R, Altendorf-Hofmann A: Hepatic metastases from colorectal carcinoma: Impact of surgical resection on the natural history. Br J Surg 77:1241-1246, 1990.
    • (1990) Br J Surg , vol.77 , pp. 1241-1246
    • Scheele, J.1    Stangl, R.2    Altendorf-Hofmann, A.3
  • 5
    • 0025862036 scopus 로고
    • One hundred patients with hepatic metastases from colorectal cancer treated by resection: Analysis of prognostic determinants
    • Doci R, Gennari L, Bignami P, et al.: One hundred patients with hepatic metastases from colorectal cancer treated by resection: Analysis of prognostic determinants. Br J Surg 78:797-801, 1991.
    • (1991) Br J Surg , vol.78 , pp. 797-801
    • Doci, R.1    Gennari, L.2    Bignami, P.3
  • 6
    • 84989626392 scopus 로고
    • Advanced colorectal cancer: Impact of chemotherapy on survival
    • Cortesi E, Padovani A, Aloe A, et al.: Advanced colorectal cancer: Impact of chemotherapy on survival. J Surg Oncol (Suppl 2):112-115, 1991.
    • (1991) J Surg Oncol , Issue.2 SUPPL. , pp. 112-115
    • Cortesi, E.1    Padovani, A.2    Aloe, A.3
  • 7
    • 0026815975 scopus 로고
    • Immunization of cancer patients using autologous cancer cells modified by the insertion of the gene for interleukin-2
    • Rosenberg SA, Anderson WF, Blaese RM, et al.: Immunization of cancer patients using autologous cancer cells modified by the insertion of the gene for interleukin-2. Hum Gene Ther 3:75-90, 1992.
    • (1992) Hum Gene Ther , vol.3 , pp. 75-90
    • Rosenberg, S.A.1    Anderson, W.F.2    Blaese, R.M.3
  • 8
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted Herpes Thymidine Kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL: Tumor chemosensitivity conferred by inserted Herpes Thymidine Kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 46:5276-5281, 1986.
    • (1986) Cancer Res , vol.46 , pp. 5276-5281
    • Moolten, F.L.1
  • 9
    • 0026568864 scopus 로고
    • Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase
    • Danielsen S, Kilstrup M, Barilla K, et al.: Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase. Mol Microbiol 6:1335-1344, 1992.
    • (1992) Mol Microbiol , vol.6 , pp. 1335-1344
    • Danielsen, S.1    Kilstrup, M.2    Barilla, K.3
  • 10
    • 0027523517 scopus 로고
    • A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expressing of Escherichia coli cystosine deaminase
    • Austin EA, Huber BE: A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expressing of Escherichia coli cystosine deaminase. Mol Pharmacol 43:380-387, 1993.
    • (1993) Mol Pharmacol , vol.43 , pp. 380-387
    • Austin, E.A.1    Huber, B.E.2
  • 11
    • 0026599586 scopus 로고
    • Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
    • Mullen CA, Kilstrup M, Blaese RM: Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system. Proc Natl Acad Sci USA 89:33-37, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 33-37
    • Mullen, C.A.1    Kilstrup, M.2    Blaese, R.M.3
  • 12
    • 0027496518 scopus 로고
    • In vivo antitumour activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
    • Huber BE, Austin EA, Good SS, et al.: In vivo antitumour activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res 53:4619-4626, 1993.
    • (1993) Cancer Res , vol.53 , pp. 4619-4626
    • Huber, B.E.1    Austin, E.A.2    Good, S.S.3
  • 13
    • 0028297316 scopus 로고
    • Tumors expressing the cylosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
    • Mullen CA, Coale MM, Lowe R, Blaese RM: Tumors expressing the cylosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor. Cancer Res 54:1503-1506, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1503-1506
    • Mullen, C.A.1    Coale, M.M.2    Lowe, R.3    Blaese, R.M.4
  • 14
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak M: Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292, 1986.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 15
    • 0021702028 scopus 로고
    • A new class of Escherichia coli recBC mutants: Implications for the role of RecBC enzyme in homologous recombination
    • Chaudhury AM, Smith GR: A new class of Escherichia coli recBC mutants: Implications for the role of RecBC enzyme in homologous recombination. Proc Natl Acad Sci USA 81:7850-7854, 1984.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7850-7854
    • Chaudhury, A.M.1    Smith, G.R.2
  • 16
    • 0016800090 scopus 로고
    • A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase
    • Sanger F, Coulson AR: A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. J Mol Biol 94:441-448, 1975.
    • (1975) J Mol Biol , vol.94 , pp. 441-448
    • Sanger, F.1    Coulson, A.R.2
  • 17
    • 0024405257 scopus 로고
    • Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA and lac repressor
    • Deuschle U, Pepperkok R, Wang F, et al.: Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA and lac repressor. Proc Natl Acad Sci USA 86:5400-5404, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5400-5404
    • Deuschle, U.1    Pepperkok, R.2    Wang, F.3
  • 18
    • 0023917842 scopus 로고
    • In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice
    • Morikawa K, Walker SM, Jessup JM, Fidler IJ: In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res 48:1943-1948, 1988.
    • (1988) Cancer Res , vol.48 , pp. 1943-1948
    • Morikawa, K.1    Walker, S.M.2    Jessup, J.M.3    Fidler, I.J.4
  • 19
    • 0025373229 scopus 로고
    • Metabolism and actions of 2-deoxy-2-D-galactose in vivo
    • Grun BR, Berger U, Oberdorfer F, et al.: Metabolism and actions of 2-deoxy-2-D-galactose in vivo. Eur J Biochem 190:11-19, 1990.
    • (1990) Eur J Biochem , vol.190 , pp. 11-19
    • Grun, B.R.1    Berger, U.2    Oberdorfer, F.3
  • 20
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63, 1983.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 21
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • Huber BE, Austin EA, Richards CA, et al.: Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci USA 91:8302-8306, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8302-8306
    • Huber, B.E.1    Austin, E.A.2    Richards, C.A.3
  • 24
    • 0020360024 scopus 로고
    • Purification and some properties of cytosine deaminase from Salmonella typhimurium
    • West TP, Shanley MS, O'Donovan GA: Purification and some properties of cytosine deaminase from Salmonella typhimurium. Biochim Biophys Acta 719:251-258, 1982.
    • (1982) Biochim Biophys Acta , vol.719 , pp. 251-258
    • West, T.P.1    Shanley, M.S.2    O'Donovan, G.A.3
  • 25
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, et al.: In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256:1550-152, 1992.
    • (1992) Science , vol.256 , pp. 1550-2152
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3
  • 26
    • 0027548077 scopus 로고
    • A clinical protocol: Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous gancyclovir
    • Oldfield EH, Culver KW, Ram Z, et al.: A clinical protocol: Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous gancyclovir. Hum Gene Ther 4:39-69, 1993.
    • (1993) Hum Gene Ther , vol.4 , pp. 39-69
    • Oldfield, E.H.1    Culver, K.W.2    Ram, Z.3
  • 27
    • 0022871958 scopus 로고
    • Clinical effects and toxicity of interleukin-2 in patients with cancer
    • Lotze MT, Matory YL, Rayner AA, et al.: Clinical effects and toxicity of interleukin-2 in patients with cancer. Cancer 58:2764-2772, 1986.
    • (1986) Cancer , vol.58 , pp. 2764-2772
    • Lotze, M.T.1    Matory, Y.L.2    Rayner, A.A.3
  • 28
    • 0024452961 scopus 로고
    • Local continuous high dose interleukin-2: A new therapeutic model for the treatment of advanced bladder cancer
    • Huland E, Huland H: Local continuous high dose interleukin-2: A new therapeutic model for the treatment of advanced bladder cancer. Cancer Res 49:1-6, 1989.
    • (1989) Cancer Res , vol.49 , pp. 1-6
    • Huland, E.1    Huland, H.2
  • 29
    • 0026701849 scopus 로고
    • Regional application of cytokine: Experience with various clinical protocols
    • Eggermont AM, Goey SH, Bolhuis RL, Stoter G: Regional application of cytokine: Experience with various clinical protocols. Pharmacol Res 26:54-55, 1992.
    • (1992) Pharmacol Res , vol.26 , pp. 54-55
    • Eggermont, A.M.1    Goey, S.H.2    Bolhuis, R.L.3    Stoter, G.4
  • 30
    • 0027058618 scopus 로고
    • A phase 2 trial of recombinant interleukin-2 and 5-fluorouracil in patients with metastatic colorectal carcinoma
    • Reid I, Sharpe I, Maxwell W, et al.: A phase 2 trial of recombinant interleukin-2 and 5-fluorouracil in patients with metastatic colorectal carcinoma. Eur J Surg Oncol 18:591-598, 1992.
    • (1992) Eur J Surg Oncol , vol.18 , pp. 591-598
    • Reid, I.1    Sharpe, I.2    Maxwell, W.3
  • 31
    • 0027443767 scopus 로고
    • A phase-III study of recombinant interleukin 2 and 5-fluorouracil chemotherapy in patients with metastatic colorectal cancer
    • Hamblin TJ, Sadhullah S, Williamson P, et al : A phase-III study of recombinant interleukin 2 and 5-fluorouracil chemotherapy in patients with metastatic colorectal cancer. Br J Cancer 68:1186-1189, 1993.
    • (1993) Br J Cancer , vol.68 , pp. 1186-1189
    • Hamblin, T.J.1    Sadhullah, S.2    Williamson, P.3
  • 32
    • 0026585044 scopus 로고
    • Interleukin-2 followed by fluorouracil and folinic acid in refractory colorectal cancer - Results of a clinical phase II study
    • Hiddeman W, Ruelfs C, Ottensmeier L, et al.: Interleukin-2 followed by fluorouracil and folinic acid in refractory colorectal cancer - Results of a clinical phase II study. Semin Oncol 19:225-227, 1992.
    • (1992) Semin Oncol , vol.19 , pp. 225-227
    • Hiddeman, W.1    Ruelfs, C.2    Ottensmeier, L.3
  • 33
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high dose interleukin-2 alone
    • Rosenberg SA, Lotze MT, Muul LM, et al.: A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high dose interleukin-2 alone. N Engl J Med 316:889-897, 1987.
    • (1987) N Engl J Med , vol.316 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.