Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)- type responses to an oral vaccine without altering mucosal IgA responses

Journal of Experimental Medicine

Volumn 185, Issue 3, 1997, Pages 415-427

  Marinaro, Mariarosaria ^a   Boyaka, Prosper N ^a   Finkelman, Fred D ^b   Kiyono, Hiroshi ^a,c   Jackson, Raymond J ^a   Jirillo, Emilio ^d   McGhee, Jerry R ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c OSAKA UNIVERSITY   (Japan)

^d UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2; LIPOSOME; RECOMBINANT INTERLEUKIN 12; SECRETORY IMMUNOGLOBULIN; TETANUS TOXOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; HELPER CELL; IMMUNE RESPONSE; IMMUNIZATION; INTRAGASTRIC DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; MUCOSA; NONHUMAN; ORAL DRUG ADMINISTRATION; PEYER PATCH; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; CHOLERA TOXIN; CYTOKINES; HYPERSENSITIVITY, DELAYED; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN-12; LIPOSOMES; MICE; MICE, INBRED C57BL; RECOMBINANT PROTEINS; TETANUS TOXOID; TH2 CELLS; VACCINES;

EID: 0031041232     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.3.415     Document Type: Article

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