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Volumn 64, Issue 12, 1996, Pages 5413-5416

Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI ENTEROTOXIN;

EID: 0029805948     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.12.5413-5416.1996     Document Type: Article
Times cited : (57)

References (27)
  • 1
    • 0028773157 scopus 로고
    • 5 ADP-ribosylating toxins: Comparative anatomy and physiology
    • 5 ADP-ribosylating toxins: comparative anatomy and physiology. Structure 2:151-158.
    • (1994) Structure , vol.2 , pp. 151-158
    • Burnett, W.N.1
  • 3
    • 0023938398 scopus 로고
    • Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens
    • Clements, J. D., N. M. Hartzog, and F. L. Lyon. 1988. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine 6:269-277.
    • (1988) Vaccine , vol.6 , pp. 269-277
    • Clements, J.D.1    Hartzog, N.M.2    Lyon, F.L.3
  • 4
    • 0028796383 scopus 로고
    • Mucosal immunoadjuvant activity of liposomes: Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with an influenza subunit vaccine and coadministered liposomes
    • DeHaan, A., H. J. Geerligs, J. P. Huchshorn, G. J. M. van Scharrenburg, A. M. Pulache, and J. Wilschut. 1995. Mucosal immunoadjuvant activity of liposomes: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with an influenza subunit vaccine and coadministered liposomes. Vaccine 13:155-162.
    • (1995) Vaccine , vol.13 , pp. 155-162
    • DeHaan, A.1    Geerligs, H.J.2    Huchshorn, J.P.3    Van Scharrenburg, G.J.M.4    Pulache, A.M.5    Wilschut, J.6
  • 5
    • 0029865302 scopus 로고    scopus 로고
    • Mucosal immunogenicity of the Escherichia coli heat-labile enterotoxin: Role of the A subunit
    • DeHaan, L., W. R. Verweij, M. Holtrop, E. Agsteribbe, and J. Wilschut. 1996. Mucosal immunogenicity of the Escherichia coli heat-labile enterotoxin: role of the A subunit. Vaccine 14:620-626
    • (1996) Vaccine , vol.14 , pp. 620-626
    • DeHaan, L.1    Verweij, W.R.2    Holtrop, M.3    Agsteribbe, E.4    Wilschut, J.5
  • 6
    • 0027500193 scopus 로고
    • Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptidc addition
    • Dertzbaugh, M. T., and C. O. Elson. 1993. Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptidc addition. Infect, Immun, 61:384-390.
    • (1993) Infect, Immun , vol.61 , pp. 384-390
    • Dertzbaugh, M.T.1    Elson, C.O.2
  • 7
    • 0028985871 scopus 로고
    • Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
    • Dickinson, U. L., and J. D. Clements. 1995. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 63:1617-1623.
    • (1995) Infect. Immun. , vol.63 , pp. 1617-1623
    • Dickinson, U.L.1    Clements, J.D.2
  • 8
    • 0030066516 scopus 로고    scopus 로고
    • Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant
    • Di Tommaso, A., G. Saletti, M. Pizza, R. Rappuoll, G. Dougan, S. Abrignani, G. Douce, and M. T. De Magistris. 1996. Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect. Immun. 64:974-979.
    • (1996) Infect. Immun. , vol.64 , pp. 974-979
    • Di Tommaso, A.1    Saletti, G.2    Pizza, M.3    Rappuoll, R.4    Dougan, G.5    Abrignani, S.6    Douce, G.7    De Magistris, M.T.8
  • 10
    • 0021260553 scopus 로고
    • Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin
    • Elson, C. O., and W. Ealdling. 1984. Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin. J. Immunol. 132:2736-2741.
    • (1984) J. Immunol. , vol.132 , pp. 2736-2741
    • Elson, C.O.1    Ealdling, W.2
  • 11
    • 0029897005 scopus 로고    scopus 로고
    • Protein engineering studies indicate the crucial importance of the A chain loop 47 to 56 for cytotoxicity of E. coli heat-labile enterotoxin
    • Feil, I. K., R. Reddy, L De Haan, E. A. Merritt, F. Van de Akker, D. R. Storm, and W. G. J. Hol. 1996. Protein engineering studies indicate the crucial importance of the A chain loop 47 to 56 for cytotoxicity of E. coli heat-labile enterotoxin. Mol. Microbiol. 20:823-832.
    • (1996) Mol. Microbiol. , vol.20 , pp. 823-832
    • Feil, I.K.1    Reddy, R.2    De Haan, L.3    Merritt, E.A.4    Van de Akker, F.5    Storm, D.R.6    Hol, W.G.J.7
  • 13
    • 0027486404 scopus 로고
    • Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems
    • Holmgren, J., N. Lycke, and C, Czerkinsky. 1993. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 11:1179-1184.
    • (1993) Vaccine , vol.11 , pp. 1179-1184
    • Holmgren, J.1    Lycke, N.2    Czerkinsky, C.3
  • 14
    • 0025816117 scopus 로고
    • Mapping epitopic regions of cholera toxin B-subunit protein
    • Kazemi, M., and R. A. Finkelstein. 1991. Mapping epitopic regions of cholera toxin B-subunit protein. Mol. Immunol. 28:865-876
    • (1991) Mol. Immunol. , vol.28 , pp. 865-876
    • Kazemi, M.1    Finkelstein, R.A.2
  • 15
    • 0027446495 scopus 로고
    • Live oral vaccines against cholera: An update
    • Levine, M. M., and J. B. Kaper. 1993. Live oral vaccines against cholera: an update. Vaccine 11:207-212.
    • (1993) Vaccine , vol.11 , pp. 207-212
    • Levine, M.M.1    Kaper, J.B.2
  • 16
    • 0026699224 scopus 로고
    • The adjuvant effect of Vibrio cholerae and Escherichia cali heat-labile enterotoxins is linked to their ADPribosyltransferase activity
    • Lycke, N., T. Tsuji, and J. Holmgren. 1992. The adjuvant effect of Vibrio cholerae and Escherichia cali heat-labile enterotoxins is linked to their ADPribosyltransferase activity. Eur. J. Immunol. 22:2277-2281.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2277-2281
    • Lycke, N.1    Tsuji, T.2    Holmgren, J.3
  • 18
    • 0023353672 scopus 로고
    • Bacteriophage lambda cloning system for the construction of directional cDNA libraries
    • Meissner, P. S., W. P. Sisk, and M. L. Berman. 1987. Bacteriophage lambda cloning system for the construction of directional cDNA libraries. Proc. Natl. Acad. Sci. USA 84:4171-4175.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4171-4175
    • Meissner, P.S.1    Sisk, W.P.2    Berman, M.L.3
  • 19
    • 0027466663 scopus 로고
    • Interaction of ADP-ribosylation factor with Escherichia coli enterotoxin that contains an inactivating lysine 112 substitution
    • Moss, J., S. J. Stanley, M. Vaughan, and T. Tsuji. 1993. Interaction of ADP-ribosylation factor with Escherichia coli enterotoxin that contains an inactivating lysine 112 substitution. J. Biol. Chem. 268:6383-6387.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6383-6387
    • Moss, J.1    Stanley, S.J.2    Vaughan, M.3    Tsuji, T.4
  • 22
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
    • Spangler, B. D. 1992. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol. Rev. 56:622-647.
    • (1992) Microbiol. Rev. , vol.56 , pp. 622-647
    • Spangler, B.D.1
  • 23
    • 0025641214 scopus 로고
    • A single amino acid substitution in the A subunit of Escherichia coli enterotoxin results in loss of its toxic activity
    • Tsuji, T., T. Inoue, A. Miyama, K. Okamoto, T. Honda, and T. Miwatani. 1990. A single amino acid substitution in the A subunit of Escherichia coli enterotoxin results in loss of its toxic activity. J. Biol. Chem. 265:22520-22525.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22520-22525
    • Tsuji, T.1    Inoue, T.2    Miyama, A.3    Okamoto, K.4    Honda, T.5    Miwatani, T.6
  • 24
    • 0028296259 scopus 로고
    • Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose
    • Uesaka, Y., Y. Otsuka, Z. Lin, S. Yamasaki, J. Yamaoka, H. Kurazono, and V. Takeda. 1994. Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose. Microb. Pathog. 16:71-76.
    • (1994) Microb. Pathog. , vol.16 , pp. 71-76
    • Uesaka, Y.1    Otsuka, Y.2    Lin, Z.3    Yamasaki, S.4    Yamaoka, J.5    Kurazono, H.6    Takeda, V.7
  • 25
    • 0026500385 scopus 로고
    • Cytoplasmic high level expression of a soluble, enzymatically active form of the Escherichia coli penicillin-binding protein 5 and purification by dye chromatography
    • VanderLlnden, M. P. G., H. Mottl, and W. Keck. 1992. Cytoplasmic high level expression of a soluble, enzymatically active form of the Escherichia coli penicillin-binding protein 5 and purification by dye chromatography. Eur. J. Biochem. 204:197-202.
    • (1992) Eur. J. Biochem. , vol.204 , pp. 197-202
    • VanderLlnden, M.P.G.1    Mottl, H.2    Keck, W.3
  • 26
    • 0025319074 scopus 로고
    • Whole cholera toxin and B subunit act synergistically as an adjuvant for the mucosal immune response of mice to keyhole limpet haemocyanin
    • Wilson, A. D., C. J. Clarke, and C. R. Stokes. 1990. Whole cholera toxin and B subunit act synergistically as an adjuvant for the mucosal immune response of mice to keyhole limpet haemocyanin. Scand. J. Immunol. 31:443-451.
    • (1990) Scand. J. Immunol. , vol.31 , pp. 443-451
    • Wilson, A.D.1    Clarke, C.J.2    Stokes, C.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.