Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization

European Journal of Immunology

Volumn 27, Issue 10, 1997, Pages 2720-2725

  Tomasi, Maurizio ^a,e   Dertzbaugh, Mark T ^b   Hearn, Thomas ^c   Hunter, Robert L ^d   Elson, Charles O ^a,f  

^a University of Alabama at Birmingham School of Medicine   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cholera toxin; Emulsion; Mucosal adjuvanticity

Indexed keywords

ADJUVANT; CHOLERA TOXIN; GANGLIOSIDE GM1; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; SECRETORY IMMUNOGLOBULIN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; EMULSION; FEMALE; IMMUNIZATION; INTESTINE SECRETION; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ALKALINE PHOSPHATASE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL VACCINES; CHOLERA TOXIN; EMULSIONS; EXCIPIENTS; FEMALE; G(M1) GANGLIOSIDE; GLUCOSYLTRANSFERASES; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MICE; MICE, INBRED ICR; MICE, INBRED STRAINS; PARTICLE SIZE; PEYER'S PATCHES; RECOMBINANT FUSION PROTEINS; SQUALENE; STREPTOCOCCUS MUTANS; VACCINATION; VACCINES, SYNTHETIC;

EID: 0030695356     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830271036     Document Type: Article

References (24)

1. Mestecky, J., McGhee, J. R. and Elson, C. O., Immunol. Allergy Clin. North. Am. 1988. 8: 349.
2. McGhee, D. W., Elson, C. O. and McGhee, J. R., Infect. Immun. 1993. 61: 4637.
3. Elson, C. O. and Dertzbaugh, M. T., in Ogra, P. L., Mestecky, J., Lamm, M. E., Strober, W., McGhee, J. R. and Bienenstock, J. (Eds.), Handbook of Mucosal Immunology, Academic Press, San Diego 1994, p. 391.
4. Levine, M. M., Kaper, J. B., Black, R. E. and Clements, M. L., Microbiol. Rev. 1983. 47: 510.
5. McGee, D. W., Elson, C. O. and McGhee, J. R., Infect. Immun. 1993. 61: 4637.
6. Lycke, N., Karlsson, U., Sjolander, A. and Magnusson, K. E., Scand. J. Immunol. 1991. 33: 691.
7. Herbert, W. J., Lancet 1965. 2: 771.
8. Hunter, R. L., Olsen, M. and Buynitzky, S., Vaccine 1991. 9: 250.
9. Hunter, R. L., Olsen, M. R. and Bennett, B., in Stewart-Tull, D. E. S. (Ed.), Theory and Practical Applications of Adjuvants, John Wiley & Sons, New York 1995, p. 52.
10. Dertzbaugh, M. T. and Elson, C. O., Infect. Immun. 1993. 61: 48.
11. Elson, C. O., Ealding, W. and Lefkowitz, J., J. Immunol. Methods 1984. 67: 101.
12. Richardson, S., Giles, J. C. and Kruger, K. S., Infect. Immun. 1984. 43: 482.
13. Russell, M. W., Brown, T. A., Radl, J., Haajman, J. J. and Mestecky, J., J. Immunol. Methods 1986. 87: 87.
14. Xu-Amano, J., Jackson, R. J., Staats, H. F., Fujihashi, K., Kiyono, H., Burrows, P. D., Elson, C. O., Pillai, S. and McGhee, J. R., J. Exp. Med. 1993. 178: 1309.
15. Finkelstein, R., Crit. Rev. Microbiol. 1973. 2: 553.
16. Elson, C. O. and Ealding, W., J. Immunol. 1984. 133: 2892.
17. Lycke, N. and Holmgren, J., Immunology 1986. 59: 301.
18. Klimpel, G. R., Asuncion, M., Haithcoat, J. and Niesel, D. W., Infect. Immun. 1995. 63: 1134.
19. Elson, C. O., Tomasi, M., Chang, T.-T., Jobling, M. G. and Holmes, R. K., FASEB J. 1995. 9: A290.
20. Michalek, S. M., Eldridge, J. H., Curtiss III, R. and Rosenthal, K. L., in Ogra, P. L., Mestecky, J., Lamm, M. E., Strober, W., McGhee, J. R. and Bienenstock, J. (Eds.), Handbook of Mucosal Immunology, Academic Press, San Diego 1994, p. 391.
21. Eldridge, J. H., Staas, J. K., Meulbroek, J. A., McGhee, J. R., Tice, T. R. and Gilley, R. M., Mol. Immunol. 1991. 28: 287.
22. Mowat, A. M., Donachie, A. M., Reid, G. and Jarrett, O., Immunology 1991. 72: 317.
23. Hunter, R. L., Strickland, F. and Kezdy, F., J. Immunol. 1981. 127: 1244.
24. Hunter, R. L., Kidd, M. R., Olsen, M. R., Patterson, P. S. and Lal, A. A., J. Immunol. 1995. 154: 1762.