Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin

Journal of Infectious Diseases

Volumn 173, Issue 3, 1996, Pages 627-635

  Takahashi, Ichiro ^b   Marinaro, Mariarosaria ^b   Kiyono, Hiroshi ^b   Jackson, Raymond J ^b   Nakagawa, Ichiro ^b   Fujihashi, Kohtaro ^b   Hamada, Shigeyuki ^b   Clements, John D ^b   Bost, Kenneth L ^b   McGhee, Jerry R ^a  

^a University of Alabama at Birmingham   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI ENTEROTOXIN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4; INTERLEUKIN 5; TETANUS TOXOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; DRUG SCREENING; ESCHERICHIA COLI; FEMALE; HELPER CELL; IMMUNOGENICITY; MALE; MUCOSA; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 19144364760     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.3.627     Document Type: Article

References (13)

1. Spangler BD. Structure and function of cholera toxin and related Escherichia coli heat-labile enterotoxins. Microbiol Rev 1992;56:622-47.
2. Clements JD, Hartzog NM, Lyon FL. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine 1988;6:269-77.
3. Walker RI, Clements JD. Use of heat-labile toxin of enterotoxigenic Escherichia coli to facilitate mucosal immunization. Vaccine Res 1993; 2:1-10.
4. Rollwaner FM, Pacheo ND, Clements JD, Pavlovskis O, Rollins DM, Walker RI. Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant. Vaccine 1993; 11: 1316-20.
5. Holmgren J, Lycke N, Czerkinsky C. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 1993; 11:1179-84.
6. Maskell DJ, Sweeney KJ, O'Callaghan D, Hormaeche CE, Liew FY, Dougan G. Salmonella typhimurium aroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systems. Microb Pathog 1987;2:211-21.
7. Cardenas L, Clements JD. Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens. Clin Microbiol Rev 1992; 5:328-42.
8. Stoll BJ, Svennerholm AM, Gothefors L, Barua D, Huda S, Holmgren J. Local and systemic antibody responses to naturally acquired enterotoxigenic Escherichia coli diarrhea in an endemic area. J Infect Dis 1986; 153:527-34.
9. Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-73.
10. Street NE, Mosmann TR. Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J 1991;5:171-7.
11. Fitch FW, McKisic MD, Lancki DW, Gajewski TF. Differential regulation of murine T lymphocyte subsets. Annu Rev Immunol 1993; 11:29-48.
12. Moore KW, O'Garra A, Malefyt RW, Vieira P, Mosman JR. Interleukin10. Annu Rev Immunol 1993; 11:165-90.
13. Paul WE. Interleukin 4/B cell stimulatory factor 1: one lymphokine, many functions. FASEB J 1987; 1:456-61.