Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 3892-3900

  Tamura, Shin Ichi ^a   Miyata, Kenji ^a   Matsuo, Kazutoshi ^a   Asanuma, Hideki ^a   Takahashi, Hidehiro ^a   Nakajima, Katsuhisa ^b   Suzuki, Yujiro ^c   Aizawa, Chikara ^c   Kurata, Takeshi ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c KITASATO INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHOLERA TOXIN B SUBUNIT; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INFLUENZA VIRUS RECOMBINANT NUCLEOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; DOSE RESPONSE; DRUG FORMULATION; DRUG MIXTURE; DRUG SYNTHESIS; FEMALE; HELPER CELL; INFLUENZA; INFLUENZA VACCINATION; INFLUENZA VIRUS A; INFLUENZA VIRUS B; INTERFERON INDUCTION; INTRANASAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; VIRUS SHEDDING;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; CHOLERA TOXIN; FEMALE; HYPERSENSITIVITY, DELAYED; INFLUENZA A VIRUS; INTERFERON TYPE II; MICE; MICE, INBRED BALB C; NASAL MUCOSA; NUCLEOPROTEINS; ORTHOMYXOVIRIDAE INFECTIONS; TH1 CELLS; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 0029935568     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Couch, R. B , and J A Kasel. 1983 Immunity to influenza in man Annu. Rev. Microbiol. 37 529
2. Murphy, B. R., and R. G. Webster. 1990. Orthomyxoviruses. In Virology, B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, eds. Raven Press, New York, p 1091.
3. Waldman, R H., F. M. Wigley, and P. A. Small Jr. 1970. Specificity of respiratory secretion antibody against influenza virus. J. Immunol. 105:1477.
4. Liew, F. Y., S. M. Russell, G. Appleyard, C M Brand, and J. Beale 1984. Cross-protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell activity. Eur. J. Immunol. 14:350.
5. Underdown, B. J., and J. M. Schiff 1986. Immunoglobulin A: strategic defense initiative at the mucosal surface. Annu Rev. Immunol. 4:389.
6. Tamura, S.-I., Y. Samegai, H. Kurata, T. Nagamine, C. Aizawa, and T. Kurata. 1988. Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit. Vaccine 6:409
7. Tamura, S.-I., H. Asanuma, Y. Ito, Y. Hirabayashi, Y. Suzuki, T. Nagamine, C. Aizawa, T. Kurata, and A. Oya. 1992. Superior cross-protective effect of nasal vaccination of subcutaneous inoculation with influenza hemagglutinin vaccine. Eur. J. Immunol. 22:477.
8. Tamura, S.-I., Y. Ito, H. Asanuma, Y. Hirabayashi, Y. Suzuki, T Nagamine, C. Aizawa, and T. Kurata. 1992. Cross-protection against influenza virus infection afforded by trivalent inactivated vaccines inoculated intranasally with cholera toxin B subunit. J. Immunol. 149:981.
9. Tamura, S.-I., A Yamanaka, M. Shimohara, T. Tomita, K. Komase, Y. Tsuda, Y. Suzuki, T. Nagamine, K. Kawahara, H. Danbara, C. Aizawa, A. Oya, and T. Kurata 1994 Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine. Vaccine 12:419.
10. Tamura, S.-I , H. Asanuma, T. Tomita, K. Komase, K. Kawahara, H. Danbara, N. Hattori, K. Watanabe, Y Suzuki, T. Nagamine, C. Aizawa, A. Oya, and T. Kurata. 1994. Escherichia coli heat-labile enterotoxin B subunits supplemented with a trace amount of the holotoxin as an adjuvant for nasal influenza vaccine. Vaccine 12:1083.
11. Hashigucci, K., H. Ogawa, T. Ishidate, R. Yamashita, H Kamiya, K Watanabe, H. Hattori, T. Sato, Y. Suzuki, T. Nagamine, C. Aizawa, S.-I. Tamura, T. Kurata, and A. Oya. 1996. Antibody responses in volunteers induced by nasal influenza vaccine combined with Escherichia coli heat-labile enterotoxin B subunit contaming a trace amount of the holotoxin. Vaccine 14:113.
12. Wraith, D. C., A. E. Vessey, and B. A. Askonas. 1987. Purified influenza virus nucleoprotein protects mice from lethal infection. J. Gen. Virol. 68.433.
13. McMichael, A. 1994. Cytotoxic T lymphocytes specific for influenza virus. Curr. Top. Microbiol. Immunol. 189:75.
14. Tite, J. P., C. Hughes-Jenkins, D. O'Callaghan, G. Dougan, S. M. Russell, X.-M. Gao, and F. Y. Liew. 1990 Antiviral immunity induced by recombinant nucleoprotein of influenza A virus. II Protection from influenza infection and mechanism of protection. Immunology 71:202.
15. Rudzik, R., R. L. Clancy, D. E. Perey, R. P. Day, and J. Bienenstock. 1975. Repopulation with IgA-containing cells of bronchial and intestinal lamina propria after transfer of homologous Peyer's patches and bronchial lymphocytes. J. Immunol. 114:1599.
16. + T cells that secrete IFN-γ and IL-5. J Immunol. 145:68.
17. McGhee, J. R., J. Mestecky, M. T. Dertzbaugh, J. H., Eldridge, M. Hirasawa, and H. Kiyono 1992. The mucosal immune system from fundamental concepts to vaccine development. Vaccine 10.75.
18. Kuper, C. F., P. J. Koornastra, D. M H. Hameleers, J Biewenga, B. J. Spit, A M. Duijvestijn, P J. C. Van Breda Vriesman, and T Sminia. 1992. The role of nasopharyngeal lymphoid tissue. Immunol. Today 13:219.
19. Asanuma, H., Y. Inaba, C. Aizawa, T Kurata, and S.-I. Tamura. 1995. Characterization of mouse nasal lymphocytes isolated by enzymatic extraction with collagenase. J. Immunol. Methods 187:41.
20. Cher, D. J., and T. R. Mosmann. 1987. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by Th1 clones. J Immunol. 138: 3688.
21. Mosmann, R. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
22. Li, L., J F. Elliott, and T. R. Mosmann. 1994. IL-10 inhibits cytokine production, vascular leakage, and swelling during Th1 cell-induced delayed-type hypersensitivity. J. Immunol. 153:3967.
23. Rota, P. A., R. A. Black, B. K. De, M. W. Harmon, and A. P. Kendal. 1990. Expression of influenza A and B virus nucleoprotein antigens in baculovirus. J Gen. Virol. 71:1545.
24. Bean, W. J., Jr., G. Sriram, and R. G. Webster. 1980. Electrophoretic analysis of iodine-labeled influenza virus RNA segments. Anal. Biochem 102:228.
25. Shu, L. L., W. J. Bean, and R. G. Webster 1993. Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990. J Virol. 67:2723.
26. Ohtomo, N., T. Muraoka, A. Tashiro, Y. Zinnaka, and K. Amako. 1976. Size and structure of the cholera toxin molecules and its subunits. J. Infect. Dis. 133:31.
27. Honma, M., T Satoh, J. Takezawa, and M. Ui. 1977. An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue. Biochem. Med. 18:257.
28. Nakamura, S., T. Morita, S. Iwanaga, M. Niwa, and K. Takashi. 1977. A sensitive substrate for the cloning enzyme in horseshoe crab hemocytes. J Biochem. 81: 1567.
29. Yetter, R. A., S. Lehrer, R. Ramphal, and P. A. Small Jr. 1980. Outcome of influenza infection: effect of site of initial infection and heterotypic immunity. Infect. Immun. 29:654
30. Davenport, F. M., A. V. Hennessy, F. M. Brandon, R. G. Webster, C D. Barrett Jr., and G. O. Lease. 1964. Comparison of serologic and febrile responses in humans to vaccination with influenza A viruses or their hemagglutinins. J. Lab. Clin. Med. 63:5.
31. Kikuta, K., H, Kurata, T. Nagamine, C Aizawa, Y. Ueno, T. Kurata, and S.-I. Tamura. 1990. Enhancement of DTH response by cholera toxin B subunit inoculated intranasally together with influenza hemagglutinin vaccine. Microbiol. Immunol 34:337.
32. Jones, P. D., and G. L. Ada. 1986. Influenza virus-specific antibody-secreting cells in the murine lung during primary influenza virus infection. J Virol. 60:614.
33. Timonen, T., C. W Reynolds, J. R. Ortalds, and B. B. Herberman. 1982. Isolation of human and rat natural killer cells. J. Immunol. Methods 51:269.
34. Lycke, N. 1986. A sensitive method for the detection of specific antibody production in different isotypes from single lamina propria plasma cells Scand. J. Immunol. 24.393.
35. Sakaguchi, M , S. Inoue, H. Miyazawa, and S -I. Tamura. 1989. Measurement of antigen-specific mouse IgB by a fluorometric reverse (IgE capture) ELISA. J. Immunol. Methods 116:181.
36. Yap, K. L., and G. L Ada. 1977. Cytotoxic T cells specific for influenza virus-infected target cells Immunology 32:151.
37. + T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype. J. Immunol. 150:5494.
38. Andrews, M. E., B. E. H. Cooper, D. B. Boyle, and G. I. Ada. 1986 The rotes of influenza virus hemagglutinin and nucleoprotein in protection: analysis using vaccinia virus recombinants. Scand. J. Immunol. 25:21.
39. Tamura, S.-I., and Y. Egashira 1976 Cellular and humoral immune responses in mice. III. Acceleration of delayed hypersensitivity response by presensitization with suboptimal dose of antigen. Immunology 30.705.
40. Tamura, S.-I , K Kikuta, T. Kobayashi, Y. Sato, and H Sato. 1987. Studies on primed precursors of effector T cells involved in delayed-type hypersensitivity to sheep red blood cells in mice. Cell. Immunol. 108:120.
41. Webster, R. G., and B. A. Askonas. 1980. Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice. Eur. J. Immunol. 10:396.
42. Morrison, L A., A. E. Lukacher, V. L. Braciale, D. P. Fan, and T. F. Braciale. 1986 Differences in antigen presentation to MHC class I- and class II-restricted influenza virus-specific cytolytic T cell clones J. Exp. Med. 163:903.
43. Yap, K L , and G. L Ada 1978. Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus. Nature 273:238.
44. Lawson, C. M., J. R. Bennink, N. P. Restifo, J. W. Yewdell, and B. R. Murphy 1994. Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant-expressing influenza A virus nucleoprotein peptide do not protect mice against challenge. J. Virol. 68:3505.
45. Bender, B. S., W. E. Bell, S. Taylor, and P. A. Small Jr. 1994. Class I major histocompatibility complex-restricted cytotoxic T lymphocytes are not necessary for heterotypic immunity to influenza. J. Infect. Dis. 170:1195.
46. Leung, K.-N., and G. L. Ada. 1982. Different functions of subsets of effector T cells in murine influenza virus infection. Cell. Immunol. 67:312
47. Taylor, P. M , A. Meager, and B. A. Askonas. 1989. Influenza virus-specific T cells lead to early interferon in lungs of infected host: development of a sensitive radioimmunoassay. J. Gen. Virol 70:975.
48. Trinchieri, G , and B. Perussia. 1985. Immune interferon: a pleiotropic lymphokine with multiple effects. Immunol. Today 6:131.
49. Tagliabue, A., A. D. Befus, D. A. Clark, and J. Bienenstock. 1982. Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria J. Exp. Med. 155:1785.
50. Adams, D. O., and T. A. Hamilton. 1987. Molecular transductional mechanisms by which IFN-γ and other signals regulate macrophage development. Immunol. Rev 97:5.
51. Bukowoki, J F., C. T. Morita, and M. B. Brenner. 1994. Recognition and destruction of virus-infected cells by human γδ CTL. J. Immunol. 153:5133.
52. Tamura, S.-I., H. Funato, Y. Hirabayashi, Y Suzuki, T. Nagamine, C Aizawa, and T Kurata. 1991. Cross-protection against influenza A virus infection passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules Eur. J Immunol. 21.1337.