-
1
-
-
0027074996
-
Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter
-
al-Ubaidi MR, Font RL, Quiambao AO, Keener MJ, Liou GI, et al. 1992. Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. J. Cell Biol. 119:1681-87
-
(1992)
J. Cell Biol.
, vol.119
, pp. 1681-1687
-
-
Al-Ubaidi, M.R.1
Font, R.L.2
Quiambao, A.O.3
Keener, M.J.4
Liou, G.I.5
-
2
-
-
0029050533
-
Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
-
Almasan A, Yin Y, Kelly RE, Lee EY, Bradley A, et al. 1995. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92:5436-40
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5436-5440
-
-
Almasan, A.1
Yin, Y.2
Kelly, R.E.3
Lee, E.Y.4
Bradley, A.5
-
4
-
-
0025201012
-
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
-
Ballester R, Marchuk D, Boguski M, Saulino A, Letcher R, et al. 1990. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 63:851-59
-
(1990)
Cell
, vol.63
, pp. 851-859
-
-
Ballester, R.1
Marchuk, D.2
Boguski, M.3
Saulino, A.4
Letcher, R.5
-
5
-
-
0029060361
-
Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: Contrasting effects of homozygous and heterozygous p53 loss
-
Blyth K, Terry A, O'Hara M, Baxter EW, Campbell M, et al. 1995. Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: contrasting effects of homozygous and heterozygous p53 loss. Oncogene 10:1717-23
-
(1995)
Oncogene
, vol.10
, pp. 1717-1723
-
-
Blyth, K.1
Terry, A.2
O'Hara, M.3
Baxter, E.W.4
Campbell, M.5
-
6
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
-
Bollag G, Clapp DW, Shih S, Adler F, Zhang YY, et al. 1996. Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat. Genet. 12:144-48
-
(1996)
Nat. Genet.
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
Adler, F.4
Zhang, Y.Y.5
-
7
-
-
0029099361
-
Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice
-
Bouffler SD, Kemp CD, Balmain A, Cox R. 1995. Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice. Cancer Res. 55:3883-89
-
(1995)
Cancer Res.
, vol.55
, pp. 3883-3889
-
-
Bouffler, S.D.1
Kemp, C.D.2
Balmain, A.3
Cox, R.4
-
8
-
-
0028349997
-
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
-
Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, et al. 1994. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev. 8:1019-29
-
(1994)
Genes Dev.
, vol.8
, pp. 1019-1029
-
-
Brannan, C.I.1
Perkins, A.S.2
Vogel, K.S.3
Ratner, N.4
Nordlund, M.L.5
-
9
-
-
0024268176
-
The adenomatous polyp and the hereditary polyposis syndrome
-
Burt R, Samowitz W. 1988. The adenomatous polyp and the hereditary polyposis syndrome. Gastroenterol. Clin. North Am. 17:657-78
-
(1988)
Gastroenterol. Clin. North Am.
, vol.17
, pp. 657-678
-
-
Burt, R.1
Samowitz, W.2
-
10
-
-
0028783773
-
Aberrant subcellular localization of BRCA1 in breast cancer
-
Chen Y, Chen CF, Riley DJ, Allred DC, Chen PL, et al. 1995. Aberrant subcellular localization of BRCA1 in breast cancer. Science 270:789-91
-
(1995)
Science
, vol.270
, pp. 789-791
-
-
Chen, Y.1
Chen, C.F.2
Riley, D.J.3
Allred, D.C.4
Chen, P.L.5
-
11
-
-
0028959978
-
DCC: Linking tumor suppressor genes and altered cell surface interactions in cancer?
-
Cho KR, Fearon ER. 1995. DCC: linking tumor suppressor genes and altered cell surface interactions in cancer? Curr. Opin. Genet. Dev. 5:72-78
-
(1995)
Curr. Opin. Genet. Dev.
, vol.5
, pp. 72-78
-
-
Cho, K.R.1
Fearon, E.R.2
-
12
-
-
0028290270
-
Murine genetic models of human disease
-
Clarke AR. 1994. Murine genetic models of human disease. Curr. Opin. Genet. Dev. 4:453-60
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, pp. 453-460
-
-
Clarke, A.R.1
-
13
-
-
0028792347
-
Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy
-
Clarke AR, Cummings MC, Harrison DJ. 1995. Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy. Oncogene 11:1913-20
-
(1995)
Oncogene
, vol.11
, pp. 1913-1920
-
-
Clarke, A.R.1
Cummings, M.C.2
Harrison, D.J.3
-
14
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke AR, Maandag ER, van Roon M, van der Lugt NMT, van der Valk M, et al. 1992. Requirement for a functional Rb-1 gene in murine development. Nature 359:328-30
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
Van Roon, M.3
Van Der Lugt, N.M.T.4
Van Der Valk, M.5
-
15
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, et al. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362:849-52.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
-
16
-
-
9444242683
-
Shared role of the pRB-related p130 and p107 proteins in limb development
-
In press
-
Cobrinik D, Lee M-H, Hannon G, Mulligan G, Bronson RT, et al. 1996. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev. In press
-
(1996)
Genes Dev.
-
-
Cobrinik, D.1
Lee, M.-H.2
Hannon, G.3
Mulligan, G.4
Bronson, R.T.5
-
17
-
-
0028913739
-
A p53-dependent mouse spindle checkpoint
-
Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S, et al. 1995. A p53-dependent mouse spindle checkpoint. Science 267:1353-56
-
(1995)
Science
, vol.267
, pp. 1353-1356
-
-
Cross, S.M.1
Sanchez, C.A.2
Morgan, C.A.3
Schimke, M.K.4
Ramel, S.5
-
18
-
-
0028812608
-
Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton
-
den Bakker MA, Tascilar M, Riegman PH, Hekman AC, Boersma W, et al. 1995. Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton. Am. J. Pathol. 147:1339-49
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 1339-1349
-
-
Den Bakker, M.A.1
Tascilar, M.2
Riegman, P.H.3
Hekman, A.C.4
Boersma, W.5
-
19
-
-
0027363063
-
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
-
Dietrich WF, Lander ES, Smith JS, Moser AR, Gould KA, et al. 1993. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75:631-39
-
(1993)
Cell
, vol.75
, pp. 631-639
-
-
Dietrich, W.F.1
Lander, E.S.2
Smith, J.S.3
Moser, A.R.4
Gould, K.A.5
-
20
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, et al. 1993. Gain of function mutations in p53. Nat. Genet. 4:42-46
-
(1993)
Nat. Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
-
21
-
-
0028951801
-
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
-
Donehower LA, Godley LA, Aldaz CM, Pyle R, Shi Y-P, et al. 1995. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Dev. 9:882-95
-
(1995)
Genes Dev.
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.-P.5
-
22
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA, et al. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215-21
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, C.A.5
-
23
-
-
0029028652
-
Characterization of the VHL tumor suppressor gene product: Localization, complex formation, and the effect of natural inactivating mutations
-
Duan DR, Humphrey JS, Chen DY, Weng Y, Sukegawa J, et al. 1995. Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations. Proc. Natl. Acad. Sci. USA 92:6459-63
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6459-6463
-
-
Duan, D.R.1
Humphrey, J.S.2
Chen, D.Y.3
Weng, Y.4
Sukegawa, J.5
-
24
-
-
0029126892
-
Inhibition of transcriptional elongation by the VHL tumor suppressor protein
-
Duan DR, Pause A, Burgess WH, Aso T, Chen DYT, et al. 1995. Inhibition of transcriptional elongation by the VHL tumor suppressor protein. Science 269:1402-6
-
(1995)
Science
, vol.269
, pp. 1402-1406
-
-
Duan, D.R.1
Pause, A.2
Burgess, W.H.3
Aso, T.4
Chen, D.Y.T.5
-
25
-
-
0027379865
-
An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): Evidence for modifying genes
-
Easton DF, Ponder MA, Huson SM, Ponder BA. 1993. An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes. Am. J. Hum. Genet. 53:305-13
-
(1993)
Am. J. Hum. Genet.
, vol.53
, pp. 305-313
-
-
Easton, D.F.1
Ponder, M.A.2
Huson, S.M.3
Ponder, B.A.4
-
26
-
-
0029135433
-
The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice
-
Elson A, Deng C, Campos-Torres J, Donehower LA, Leder P. 1995. The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice. Oncogene 11:181-90
-
(1995)
Oncogene
, vol.11
, pp. 181-190
-
-
Elson, A.1
Deng, C.2
Campos-Torres, J.3
Donehower, L.A.4
Leder, P.5
-
27
-
-
0025785484
-
Molecular cloning, chromosomal mapping and expression of the cDNA for p107, a retinoblastoma gene product-related protein
-
Ewen ME, Xing Y, Lawrence JB, Livingston DM. 1991. Molecular cloning, chromosomal mapping and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66:1155-64
-
(1991)
Cell
, vol.66
, pp. 1155-1164
-
-
Ewen, M.E.1
Xing, Y.2
Lawrence, J.B.3
Livingston, D.M.4
-
28
-
-
0025056930
-
Identification of a chromsome 18q gene that is altered in colorectal cancers
-
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, et al. 1990. Identification of a chromsome 18q gene that is altered in colorectal cancers. Science 247:49-56
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
Kern, S.E.4
Simons, J.W.5
-
29
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. 1990. A genetic model for colorectal tumorigenesis. Cell 61:759-67
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
30
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27-deficient mice
-
Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, et al. 1996. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27-deficient mice. Cell 733-44
-
(1996)
Cell
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
-
31
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field S, Tsai F-Y, Kuo F, Zubiaga AM, Kaelin WG, et al. 1996. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85:549-61
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.1
Tsai, F.-Y.2
Kuo, F.3
Zubiaga, A.M.4
Kaelin, W.G.5
-
32
-
-
0028567875
-
A targeted chain-termination in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R, Edelman W, Yang K, van Leeuwen C, Carlson C, et al. 1994. A targeted chain-termination in the mouse Apc gene results in multiple intestinal tumors. Proc. Natl. Acad. Sci. USA 91:8969-73
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelman, W.2
Yang, K.3
Van Leeuwen, C.4
Carlson, C.5
-
33
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend SJ, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, et al. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643-46
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.J.1
Bernards, R.2
Rogelj, S.3
Weinberg, R.A.4
Rapaport, J.M.5
-
35
-
-
0028148858
-
E2F-4, a new member of the E2F transcription factor family, interacts with p107
-
Ginsberg D, Vairo G, Chittenden T, Xiao Z, Xu G, et al. 1994. E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev. 8:2665-79
-
(1994)
Genes Dev.
, vol.8
, pp. 2665-2679
-
-
Ginsberg, D.1
Vairo, G.2
Chittenden, T.3
Xiao, Z.4
Xu, G.5
-
36
-
-
0030051903
-
Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
-
Gowen LC, Johnson BL, Latour AM, Sulik KK, Koller BH. 1996. Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat. Genet. 12:191-94
-
(1996)
Nat. Genet.
, vol.12
, pp. 191-194
-
-
Gowen, L.C.1
Johnson, B.L.2
Latour, A.M.3
Sulik, K.K.4
Koller, B.H.5
-
37
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC. 1994. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54:4855-78
-
(1994)
Cancer Res.
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
38
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, et al. 1991. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66:589-600
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
-
39
-
-
0029009926
-
Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds
-
Gruis NA, van der Velden PA, Sandkuijl LA, Prins DE, Weaver-Feldhaus J, et al. 1995. Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds. Nat. Genet. 10:351-53
-
(1995)
Nat. Genet.
, vol.10
, pp. 351-353
-
-
Gruis, N.A.1
Van Der Velden, P.A.2
Sandkuijl, L.A.3
Prins, D.E.4
Weaver-Feldhaus, J.5
-
40
-
-
0028059099
-
Deletion of a polymerase B gene segment in T cells using cell type-specific gene targeting
-
Gu H, Marth JD, Orban PC, Mossman H, Rajewsky K. 1994. Deletion of a polymerase B gene segment in T cells using cell type-specific gene targeting. Science 265:103-6
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossman, H.4
Rajewsky, K.5
-
41
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulos PG, Gailani MG, Shanley S, et al. 1996. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85:841-51
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulos, P.G.3
Gailani, M.G.4
Shanley, S.5
-
42
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, et al. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-53
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
-
43
-
-
15844371372
-
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
-
Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, et al. 1996. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell 85:1009-23
-
(1996)
Cell
, vol.85
, pp. 1009-1023
-
-
Hakem, R.1
De La Pompa, J.L.2
Sirard, C.3
Mo, R.4
Woo, M.5
-
44
-
-
0027137004
-
Anti-Ras drugs come of age
-
Hancock LF. 1993. Anti-Ras drugs come of age. Curr. Biol. 3:770-72
-
(1993)
Curr. Biol.
, vol.3
, pp. 770-772
-
-
Hancock, L.F.1
-
45
-
-
0029059790
-
Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
-
Hanks M, Wurst W, Anson-Cartwright L, Auerbach AB, Joyner AL. 1995. Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269:679-82
-
(1995)
Science
, vol.269
, pp. 679-682
-
-
Hanks, M.1
Wurst, W.2
Anson-Cartwright, L.3
Auerbach, A.B.4
Joyner, A.L.5
-
46
-
-
0027142956
-
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
-
Hannon GJ, Demetrick D, Beach D. 1993. Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev. 7:2378-91
-
(1993)
Genes Dev.
, vol.7
, pp. 2378-2391
-
-
Hannon, G.J.1
Demetrick, D.2
Beach, D.3
-
48
-
-
0027521657
-
Spontaneous and carcinogen-induced tumors in p53-deficient mice
-
Harvey M, McArthur MJ, Montgomery CA, Butel JS, Bradley A, Donehower LA. 1993. Spontaneous and carcinogen-induced tumors in p53-deficient mice. Nat. Genet. 5:225-29
-
(1993)
Nat. Genet.
, vol.5
, pp. 225-229
-
-
Harvey, M.1
McArthur, M.J.2
Montgomery, C.A.3
Butel, J.S.4
Bradley, A.5
Donehower, L.A.6
-
49
-
-
0028937476
-
Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin
-
Harvey M, Vogel H, Lee EY, Bradley A, Donehower LA. 1995. Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin. Cancer Res. 55:1146-51
-
(1995)
Cancer Res.
, vol.55
, pp. 1146-1151
-
-
Harvey, M.1
Vogel, H.2
Lee, E.Y.3
Bradley, A.4
Donehower, L.A.5
-
50
-
-
0028842340
-
A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice
-
Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. 1995. A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nat. Genet. 305-311
-
(1995)
Nat. Genet.
, pp. 305-311
-
-
Harvey, M.1
Vogel, H.2
Morris, D.3
Bradley, A.4
Bernstein, A.5
Donehower, L.A.6
-
51
-
-
0028587166
-
The genetics of Wilms tumor - A case of disrupted development
-
Hastie ND. 1994. The genetics of Wilms tumor - a case of disrupted development. Annu. Rev. Genet. 28:523-58
-
(1994)
Annu. Rev. Genet.
, vol.28
, pp. 523-558
-
-
Hastie, N.D.1
-
52
-
-
0026429190
-
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
-
Hasty P, Ramirez-Solis R, Krumlauf R, Bradley A. 1991. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature 350:243-46
-
(1991)
Nature
, vol.350
, pp. 243-246
-
-
Hasty, P.1
Ramirez-Solis, R.2
Krumlauf, R.3
Bradley, A.4
-
53
-
-
0025727771
-
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in e mu-myc transgenic mice
-
Haupt Y, Alexander WS, Barri G, Klinken SP, Adams JM. 1991. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65:753-63
-
(1991)
Cell
, vol.65
, pp. 753-763
-
-
Haupt, Y.1
Alexander, W.S.2
Barri, G.3
Klinken, S.P.4
Adams, J.M.5
-
54
-
-
0028788570
-
Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein
-
Henkemeyer M, Rossi DJ, Holmyard DP, Pun MC, Mbamalu G, et al. 1995. Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein. Nature 377:695-701
-
(1995)
Nature
, vol.377
, pp. 695-701
-
-
Henkemeyer, M.1
Rossi, D.J.2
Holmyard, D.P.3
Pun, M.C.4
Mbamalu, G.5
-
55
-
-
0027458433
-
Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer
-
Hino O, Klein-Szanto AJ, Freed JJ, Testa JR, Brown DQ, et al. 1993. Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. USA 327-31
-
(1993)
Proc. Natl. Acad. Sci. USA
, pp. 327-331
-
-
Hino, O.1
Klein-Szanto, A.J.2
Freed, J.J.3
Testa, J.R.4
Brown, D.Q.5
-
56
-
-
0029892494
-
MADR1, a MAD-related protein that functions in BMP2 signaling pathways
-
Hoodless PA, Haerry T, Abdollah S, Stapleton M, O'Connor MB, et al. 1996. MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85:489-500
-
(1996)
Cell
, vol.85
, pp. 489-500
-
-
Hoodless, P.A.1
Haerry, T.2
Abdollah, S.3
Stapleton, M.4
O'Connor, M.B.5
-
57
-
-
0025304297
-
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
-
Horowitz JM, Park SH, Begenmann E, Cheng JC, Yandell DW, et al. 1990. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc. Natl. Acad. Sci. USA 87:2775-79
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2775-2779
-
-
Horowitz, J.M.1
Park, S.H.2
Begenmann, E.3
Cheng, J.C.4
Yandell, D.W.5
-
58
-
-
0028227260
-
Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
-
Howes KA, Ransom N, Papermaster DS, Lasudry JGH, Albert DM, Windle JJ. 1994. Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev. 8:1300-10
-
(1994)
Genes Dev.
, vol.8
, pp. 1300-1310
-
-
Howes, K.A.1
Ransom, N.2
Papermaster, D.S.3
Lasudry, J.G.H.4
Albert, D.M.5
Windle, J.J.6
-
59
-
-
0029134878
-
Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis
-
Hsu B, Marin MC, el-Naggar AK, Stephens LC, Brisbay S, McDonnell TJ. 1995. Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis. Oncogene 11:175-79
-
(1995)
Oncogene
, vol.11
, pp. 175-179
-
-
Hsu, B.1
Marin, M.C.2
El-Naggar, A.K.3
Stephens, L.C.4
Brisbay, S.5
McDonnell, T.J.6
-
60
-
-
0028174064
-
Heterozygous Rb-1 delta 20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance
-
Hu N, Gutsmann A, Herbert DC, Bradley A, Lee WH, Lee EY-HP. 1994. Heterozygous Rb-1 delta 20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance. Oncogene 9:1021-27
-
(1994)
Oncogene
, vol.9
, pp. 1021-1027
-
-
Hu, N.1
Gutsmann, A.2
Herbert, D.C.3
Bradley, A.4
Lee, W.H.5
Lee, E.Y.-H.P.6
-
61
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T, Fazeli A, Schmidt E, Bronson R, Goodell M, Weinberg R. 1992. Effects of an Rb mutation in the mouse. Nature 359:295-300
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmidt, E.3
Bronson, R.4
Goodell, M.5
Weinberg, R.6
-
62
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, et al. 1994. Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4:1-7
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
-
63
-
-
0028307836
-
Tumourigenic and developmental consequences of a targeted Nf1 mutation in the mouse
-
Jacks T, Shih TS, Schmitt EM, Bronson RD, Bernards A, Weinberg RA. 1994. Tumourigenic and developmental consequences of a targeted Nf1 mutation in the mouse. Nat. Genet. 7:353-61
-
(1994)
Nat. Genet.
, vol.7
, pp. 353-361
-
-
Jacks, T.1
Shih, T.S.2
Schmitt, E.M.3
Bronson, R.D.4
Bernards, A.5
Weinberg, R.A.6
-
64
-
-
13344249759
-
BRCA1 is secreted and exhibits properties of a granin
-
Jensen RA, Thompson ME, Jetton TJ, Szabo CI, van der Meer R, et al. 1996. BRCA1 is secreted and exhibits properties of a granin. Nat. Genet. 6:303-8
-
(1996)
Nat. Genet.
, vol.6
, pp. 303-308
-
-
Jensen, R.A.1
Thompson, M.E.2
Jetton, T.J.3
Szabo, C.I.4
Van Der Meer, R.5
-
65
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, et al. 1996. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272:1668-71
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
-
66
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones SN, Roe AE, Donehower LA, Bradley A. 1995. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378:206-8
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
67
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia
-
Kastan M, Zhan Q, El-Deiry WS, Carrier F, Jacks T, et al. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia. Cell 71:587-97
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
-
68
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
Kemp CJ, Donehower LA, Bradley A, Balmain A. 1993. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74:813-22
-
(1993)
Cell
, vol.74
, pp. 813-822
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
69
-
-
0028168643
-
p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
-
Kemp CJ, Wheldon T, Balmain A. 1994. p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nat. Genet. 8:66-69
-
(1994)
Nat. Genet.
, vol.8
, pp. 66-69
-
-
Kemp, C.J.1
Wheldon, T.2
Balmain, A.3
-
70
-
-
0029147430
-
Binding of the vonHippel-Lindau tumor suppressor protein to elongin B and C
-
Kibel A, Iliopaoulos O, DeCaprio JA, Kaelin WG. 1995. Binding of the vonHippel-Lindau tumor suppressor protein to elongin B and C. Science 269:1444-46
-
(1995)
Science
, vol.269
, pp. 1444-1446
-
-
Kibel, A.1
Iliopaoulos, O.2
Decaprio, J.A.3
Kaelin, W.G.4
-
71
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su L-K, Vogelstein B, Bryan TM, et al. 1991. Identification of FAP locus genes from chromosome 5q21. Science 253:661-65
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.-K.3
Vogelstein, B.4
Bryan, T.M.5
-
72
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27
-
Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, et al. 1996. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27. Cell 85:721-32
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
-
73
-
-
0017819319
-
Retinoblastoma: A proteotypic hereditary neoplasm
-
Knudson AG. 1978. Retinoblastoma: a proteotypic hereditary neoplasm. Semin. Oncol. 5:57-60
-
(1978)
Semin. Oncol.
, vol.5
, pp. 57-60
-
-
Knudson, A.G.1
-
74
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, Prives C. 1996. p53: puzzle and paradigm. Genes Dev. 10:1054-72
-
(1996)
Genes Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
75
-
-
0028830856
-
A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer
-
Kobayashi T, Hirayama Y, Kobayashi E, Kubo Y, Hino O. 1995. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nat. Genet. 9:70-74
-
(1995)
Nat. Genet.
, vol.9
, pp. 70-74
-
-
Kobayashi, T.1
Hirayama, Y.2
Kobayashi, E.3
Kubo, Y.4
Hino, O.5
-
76
-
-
0028960617
-
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. 1995. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol. 69:2491-500
-
(1995)
J. Virol.
, vol.69
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
77
-
-
0027182741
-
WT-1 is required for early kidney development
-
Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, et al. 1993. WT-1 is required for early kidney development. Cell 74:679-91
-
(1993)
Cell
, vol.74
, pp. 679-691
-
-
Kreidberg, J.A.1
Sariola, H.2
Loring, J.M.3
Maeda, M.4
Pelletier, J.5
-
79
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA methylation
-
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, et al. 1995. Suppression of intestinal neoplasia by DNA methylation. Cell 81:197-205
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
Dickinson, S.L.4
Jung, W.E.5
-
80
-
-
0030045594
-
Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia
-
Largaespada DA, Brannan CI, Jenkins NA, Copeland NG. 1996. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia. Nat. Genet. 12:137-43
-
(1996)
Nat. Genet.
, vol.12
, pp. 137-143
-
-
Largaespada, D.A.1
Brannan, C.I.2
Jenkins, N.A.3
Copeland, N.G.4
-
81
-
-
0029071508
-
Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing
-
Larsson SH, Charlieu JP, Miyagawa K, Engelkamp D, Rassoulzadegan M, et al. 1995. Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing. Cell 81:391-401
-
(1995)
Cell
, vol.81
, pp. 391-401
-
-
Larsson, S.H.1
Charlieu, J.P.2
Miyagawa, K.3
Engelkamp, D.4
Rassoulzadegan, M.5
-
82
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J, Yao M, Duh F-M, et al. 1993. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260:1317-20
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
Yao, M.4
Duh, F.-M.5
-
83
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee EY-HP, Chang C-Y, Hu N, Wang Y-CJ, Lai C-C, et al. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359:288-95
-
(1992)
Nature
, vol.359
, pp. 288-295
-
-
Lee, E.Y.-H.P.1
Chang, C.-Y.2
Hu, N.3
Wang, Y.-C.J.4
Lai, C.-C.5
-
84
-
-
0028131540
-
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
-
Lee EY-HP, Hu N, Yuan S-SF, Cox LA, Bradley A, et al. 1994. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8:2008-21
-
(1994)
Genes Dev.
, vol.8
, pp. 2008-2021
-
-
Lee, E.Y.-H.P.1
Hu, N.2
Yuan, S.-S.F.3
Cox, L.A.4
Bradley, A.5
-
85
-
-
0028033027
-
Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice
-
Lee JM, Abrahamson JL, Kandel R, Donehower LA, Bernstein A. 1994. Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice. Oncogene 9:3731-36
-
(1994)
Oncogene
, vol.9
, pp. 3731-3736
-
-
Lee, J.M.1
Abrahamson, J.L.2
Kandel, R.3
Donehower, L.A.4
Bernstein, A.5
-
86
-
-
0029736909
-
Targeted disruption of p107: Functional overlap between p107 and Rb
-
Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, et al. 1996. Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev. 10:1621-32
-
(1996)
Genes Dev.
, vol.10
, pp. 1621-1632
-
-
Lee, M.H.1
Williams, B.O.2
Mulligan, G.3
Mukai, S.4
Bronson, R.T.5
-
87
-
-
0025354907
-
Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps
-
Leppert M, Burt R, Hughes JP, Samowitz W, Nakamura Y, et al. 1990. Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. N. Engl. J. Med. 322:904-8
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 904-908
-
-
Leppert, M.1
Burt, R.2
Hughes, J.P.3
Samowitz, W.4
Nakamura, Y.5
-
88
-
-
0027135209
-
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E
-
Li Y, Graham C, Lacy S, Duncan AMV, Whyte P. 1993. The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev. 7:2366-77
-
(1993)
Genes Dev.
, vol.7
, pp. 2366-2377
-
-
Li, Y.1
Graham, C.2
Lacy, S.3
Amv, D.4
Whyte, P.5
-
89
-
-
0029931509
-
A human Mad protein acting as a BMP-regulated transcriptional activator
-
Liu F, Hata A, Baker JC, Doody J, Carcamo J, et al. 1996. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381:620-23
-
(1996)
Nature
, vol.381
, pp. 620-623
-
-
Liu, F.1
Hata, A.2
Baker, J.C.3
Doody, J.4
Carcamo, J.5
-
90
-
-
0028864149
-
A mutant p53 antagonizes the deregulated c-myc- Mediated enhancement of apoptosis and decrease in leukemogenicity
-
Lotem J, Sachs L. 1995. A mutant p53 antagonizes the deregulated c-myc- mediated enhancement of apoptosis and decrease in leukemogenicity. Proc. Natl. Acad. Sci. USA 10:9672-76
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.10
, pp. 9672-9676
-
-
Lotem, J.1
Sachs, L.2
-
91
-
-
0027451668
-
p53-dependent apoptosis modulates the cytoxicity of anticancer agents
-
Lowe SM, Ruley HE, Jacks T, Housman DE. 1993. p53-dependent apoptosis modulates the cytoxicity of anticancer agents. Cell 74:957-67
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.M.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
92
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, et al. 1994. p53 status and the efficacy of cancer therapy in vivo. Science 266:807-10
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
-
93
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt ES, Smith SW, Osborne BA, Jacks T. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-49
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.S.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
95
-
-
0028101051
-
Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice
-
Maandag ECR, van der Valk M, Vlaar M, Feltkamp C, O'Brien J, et al. 1994. Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice. EMBO J. 13:4260-68
-
(1994)
EMBO J.
, vol.13
, pp. 4260-4268
-
-
Maandag, E.C.R.1
Van Der Valk, M.2
Vlaar, M.3
Feltkamp, C.4
O'Brien, J.5
-
96
-
-
0029910628
-
Loss of Rb activates both p53-dependent and -independent cell death pathways in the developing mouse nervous system
-
In press
-
Macleod KF, Hu Y, Jacks T. 1996. Loss of Rb activates both p53-dependent and -independent cell death pathways in the developing mouse nervous system. EMBO J. In press
-
(1996)
EMBO J.
-
-
Macleod, K.F.1
Hu, Y.2
Jacks, T.3
-
98
-
-
0027315653
-
p53 and the Li-Fraumeni syndrome
-
Malkin D. 1993. p53 and the Li-Fraumeni syndrome. Cancer Genet. Cytogenet. 66:83-92
-
(1993)
Cancer Genet. Cytogenet.
, vol.66
, pp. 83-92
-
-
Malkin, D.1
-
99
-
-
0028020522
-
Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis
-
Marin MC, Hs B, Meyn RE, Donehower LA, el-Naggar AK, McDonnell TJ. 1994. Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis. Oncogene 9:3107-12
-
(1994)
Oncogene
, vol.9
, pp. 3107-3112
-
-
Marin, M.C.1
Hs, B.2
Meyn, R.E.3
Donehower, L.A.4
El-Naggar, A.K.5
McDonnell, T.J.6
-
100
-
-
0025251137
-
The GAP-related domain of the neurofibromatosi type 1 gene product interacts with ras p21
-
Martin GA, Viskochil D, Bollag G, McCabe PC, Crosier WJ, et al. 1990. The GAP-related domain of the neurofibromatosi type 1 gene product interacts with ras p21. Cell 63:843-49
-
(1990)
Cell
, vol.63
, pp. 843-849
-
-
Martin, G.A.1
Viskochil, D.2
Bollag, G.3
McCabe, P.C.4
Crosier, W.J.5
-
101
-
-
0026621796
-
Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice
-
Matzuk MM, Finegold MJ, Su JG, Hsueh AJ, Bradley A. 1992. Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360:313-19
-
(1992)
Nature
, vol.360
, pp. 313-319
-
-
Matzuk, M.M.1
Finegold, M.J.2
Su, J.G.3
Hsueh, A.J.4
Bradley, A.5
-
102
-
-
12044258811
-
Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain
-
Mayol X, Grana X, Baldi A, Sang N, Hu Q, Giordano A. 1993. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8:2561-66
-
(1993)
Oncogene
, vol.8
, pp. 2561-2566
-
-
Mayol, X.1
Grana, X.2
Baldi, A.3
Sang, N.4
Hu, Q.5
Giordano, A.6
-
104
-
-
0028500365
-
Gene targeting in the mouse
-
Melton DW. 1994. Gene targeting in the mouse. BioEssays 16:633-38
-
(1994)
BioEssays
, vol.16
, pp. 633-638
-
-
Melton, D.W.1
-
105
-
-
0028047723
-
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
-
Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, et al. 1994. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 54:614-17
-
(1994)
Cancer Res.
, vol.54
, pp. 614-617
-
-
Merritt, A.J.1
Potten, C.S.2
Kemp, C.J.3
Hickman, J.A.4
Balmain, A.5
-
107
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, et al. 1994. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266:66-71
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
-
108
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna R, Wagner DS, Lozano G. 1995. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378:203-6
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
109
-
-
0027934570
-
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
-
Morgenbesser SD, Williams BO, Jacks T, DePinho RA. 1994. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371:72-74
-
(1994)
Nature
, vol.371
, pp. 72-74
-
-
Morgenbesser, S.D.1
Williams, B.O.2
Jacks, T.3
DePinho, R.A.4
-
110
-
-
0027340690
-
Min, a mutation in the murine Ape gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
-
Min, a mutation in the murine Ape gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. Proc. Natl. Acad. Sci. USA 8977-81
-
(1993)
Proc. Natl. Acad. Sci. USA
, pp. 8977-8981
-
-
Moser, A.R.1
Mattes, E.M.2
Dove, W.F.3
Lindstrom, M.J.4
Haag, J.D.5
Gould, M.N.6
-
111
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser AR, Pilot HC, Dove WF. 1990. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247:322-24
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pilot, H.C.2
Dove, W.F.3
-
112
-
-
0029125021
-
Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation
-
Moser AR, Shoemaker AR, Connelly CS, Clipson L, Gould KA, et al. 1995. Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation. Dev. Dyn. 203:422-33
-
(1995)
Dev. Dyn.
, vol.203
, pp. 422-433
-
-
Moser, A.R.1
Shoemaker, A.R.2
Connelly, C.S.3
Clipson, L.4
Gould, K.A.5
-
113
-
-
0029858044
-
Mutations in the p53 and SCID genes cooperate in lymphomagenesis
-
Nacht M, Strasser A, Chan YR, Harris A, Schlissel M, et al. 1996. Mutations in the p53 and SCID genes cooperate in lymphomagenesis. Genes Dev. 10:2055-66
-
(1996)
Genes Dev.
, vol.10
, pp. 2055-2066
-
-
Nacht, M.1
Strasser, A.2
Chan, Y.R.3
Harris, A.4
Schlissel, M.5
-
114
-
-
0030010591
-
Mice lacking p27 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Nakayama K, Ishida N, Shirane M, Inotnata A, Inoue T, et al. 1996. Mice lacking p27 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-20
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inotnata, A.4
Inoue, T.5
-
115
-
-
0027770784
-
Identification and characterization of the tuberous sclerosis gene on chromosome 16
-
Nellist M, Janssen B, Brook-Carter PT, Hesseling-Jansenn ALW, Maheshwar MM, et al. 1993. Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 75:1305-15
-
(1993)
Cell
, vol.75
, pp. 1305-1315
-
-
Nellist, M.1
Janssen, B.2
Brook-Carter, P.T.3
Hesseling-Jansenn, A.L.W.4
Maheshwar, M.M.5
-
116
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins J. 1992. E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424-29
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.1
-
117
-
-
0029006469
-
A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice
-
Nicol CJ, Harrison ML, Laposa RR, Gimelshtein IL, Wells PG. 1995. A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nat. Genet. 10:181-87
-
(1995)
Nat. Genet.
, vol.10
, pp. 181-187
-
-
Nicol, C.J.1
Harrison, M.L.2
Laposa, R.R.3
Gimelshtein, I.L.4
Wells, P.G.5
-
118
-
-
0029874308
-
p53-dependent apoptosis suppresses radiation-induced teratogenesis
-
Norimura T, Nomoto S, Katsuki M, Gondo Y, Kondo S. 1996. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 2:577-81
-
(1996)
Nat. Med.
, vol.2
, pp. 577-581
-
-
Norimura, T.1
Nomoto, S.2
Katsuki, M.3
Gondo, Y.4
Kondo, S.5
-
119
-
-
13344279424
-
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers
-
Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, et al. 1996. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84:587-97
-
(1996)
Cell
, vol.84
, pp. 587-597
-
-
Ohta, M.1
Inoue, H.2
Cotticelli, M.G.3
Kastury, K.4
Baffa, R.5
-
120
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, Taketo M. 1995. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. USA 92:4482-86
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
Taketo, M.6
-
121
-
-
0028334011
-
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
-
Pan H, Griep A. 1994. Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev. 8:1285-99
-
(1994)
Genes Dev.
, vol.8
, pp. 1285-1299
-
-
Pan, H.1
Griep, A.2
-
122
-
-
0029093605
-
Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
-
Pan H, Griep AE. 1995. Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev. 9:2157-69
-
(1995)
Genes Dev.
, vol.9
, pp. 2157-2169
-
-
Pan, H.1
Griep, A.E.2
-
123
-
-
0025506247
-
Oncogenes at viral integration sites
-
Peters G. 1990. Oncogenes at viral integration sites. Cell Growth Differ 1:503-10
-
(1990)
Cell Growth Differ
, vol.1
, pp. 503-510
-
-
Peters, G.1
-
124
-
-
0028957642
-
Mutations in the APC gene and their implications for protein structure and function
-
Polakis P. 1995. Mutations in the APC gene and their implications for protein structure and function. Curr. Opin. Genet. Dev. 5:66-71
-
(1995)
Curr. Opin. Genet. Dev.
, vol.5
, pp. 66-71
-
-
Polakis, P.1
-
125
-
-
0028176453
-
Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene
-
Purdie CA, Harrison DJ, Peter A, Dobbie L, White S, et al. 1994. Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene. Oncogene 9:603-9
-
(1994)
Oncogene
, vol.9
, pp. 603-609
-
-
Purdie, C.A.1
Harrison, D.J.2
Peter, A.3
Dobbie, L.4
White, S.5
-
126
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin XQ, Livingston DM, Kaelin WG, Adams PD. 1994. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA 91:10918-22
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin, W.G.3
Adams, P.D.4
-
127
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ. 1995. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83:993-1000
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
130
-
-
0028807189
-
Neurofibromin-deficient fibroblasts fail to form perineurium in vitro
-
Rosenbaum T, Boissy YL, Kombrinck K, Brannan CI, Jenkins NA, et al. 1995. Neurofibromin-deficient fibroblasts fail to form perineurium in vitro. Development 121:3583-92
-
(1995)
Development
, vol.121
, pp. 3583-3592
-
-
Rosenbaum, T.1
Boissy, Y.L.2
Kombrinck, K.3
Brannan, C.I.4
Jenkins, N.A.5
-
131
-
-
0027245423
-
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
-
Rouleau GA, Merel P, Lutchman M, Sanson M, Zucman J, et al. 1993. Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature 363:515-21
-
(1993)
Nature
, vol.363
, pp. 515-521
-
-
Rouleau, G.A.1
Merel, P.2
Lutchman, M.3
Sanson, M.4
Zucman, J.5
-
132
-
-
0029664368
-
Binding of GSK3B to the APC-B-catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. 1996. Binding of GSK3B to the APC-B-catenin complex and regulation of complex assembly. Science 272:1023-26
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
133
-
-
0027738023
-
Association of the APC gene product with beta-catenin
-
Rubinfeld B, Souza B, Albert I, Muller O, Chamberlain SH, et al. 1993. Association of the APC gene product with beta-catenin. Science 262:1731-34
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
-
134
-
-
0027729729
-
MyoD or Myf-5 is required for the formation of skeletal muscle
-
Rudnicki MA, Schnegelsberg PN, Stead RH, Braun T, Arnold HH, Jaenisch R. 1993. MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75:1351-59
-
(1993)
Cell
, vol.75
, pp. 1351-1359
-
-
Rudnicki, M.A.1
Schnegelsberg, P.N.2
Stead, R.H.3
Braun, T.4
Arnold, H.H.5
Jaenisch, R.6
-
135
-
-
0029007405
-
A subset of p53-deficient embryos exhibit exencephaly
-
Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T.1995. A subset of p53-deficient embryos exhibit exencephaly. Nat. Genet. 10:175-80
-
(1995)
Nat. Genet.
, vol.10
, pp. 175-180
-
-
Sah, V.P.1
Attardi, L.D.2
Mulligan, G.J.3
Williams, B.O.4
Bronson, R.T.5
Jacks, T.6
-
136
-
-
0028040522
-
The molecular genetics of tuberous sclerosis
-
Sampson JR, Harris PC. 1994. The molecular genetics of tuberous sclerosis. Hum. Mol. Genet. 3:1477-80
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1477-1480
-
-
Sampson, J.R.1
Harris, P.C.2
-
137
-
-
0028948866
-
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
-
Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, et al. 1995. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Natl. Acad. Sci. USA 92:2403-7
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2403-2407
-
-
Sardet, C.1
Vidal, M.2
Cobrinik, D.3
Geng, Y.4
Onufryk, C.5
-
138
-
-
0030570004
-
Location of BACA1 in human breast and ovarian cancer cells
-
Scully R, Ganesan S, Brown M, De Caprio JA, et al. 1996. Location of BACA1 in human breast and ovarian cancer cells. Science 272:123-25
-
(1996)
Science
, vol.272
, pp. 123-125
-
-
Scully, R.1
Ganesan, S.2
Brown, M.3
De Caprio, J.A.4
-
139
-
-
0027769876
-
A new regulatory motif in cell- Cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, Beach D. 1993. A new regulatory motif in cell- cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-7
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
140
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
Serrano M, Lee H-W, Chin L, Cordon-Cardi C, Beach D, DePinho RA. 1996. Role of the INK4a locus in tumor suppression and cell mortality. Cell 85:27-37
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.-W.2
Chin, L.3
Cordon-Cardi, C.4
Beach, D.5
DePinho, R.A.6
-
141
-
-
0028061670
-
Deregulated expression of E2F-1 induces S- Phase entry and leads to apoptosis
-
Shan B, Lee W-H. 1994. Deregulated expression of E2F-1 induces S- phase entry and leads to apoptosis. Mol. Cell. Biol. 14:299-309
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 299-309
-
-
Shan, B.1
Lee, W.-H.2
-
142
-
-
0028988585
-
Inhibitors of mammalian Gl cyclin-dependent kinases
-
Sherr CJ, Roberts JM. 1995. Inhibitors of mammalian Gl cyclin-dependent kinases. Genes Dev. 9:1149-63
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
143
-
-
0028981283
-
N-ethyl-N-nitrosourea treatment of multiple intestinal neoplasia (Min) mice: Age-related effects on the formation of intestinal adenomas, cystic crypts, and epidermoid cysts
-
Shoemaker AR, Moser AR, Dove WF. 1995. N-ethyl-N-nitrosourea treatment of multiple intestinal neoplasia (Min) mice: age-related effects on the formation of intestinal adenomas, cystic crypts, and epidermoid cysts. Cancer Res. 55:4479-85
-
(1995)
Cancer Res.
, vol.55
, pp. 4479-4485
-
-
Shoemaker, A.R.1
Moser, A.R.2
Dove, W.F.3
-
144
-
-
15844384990
-
The FHIT gene 3p14.2 is abnormal in lung cancer
-
Sozzi G, Veronese ML, Negrini M, Baffa R, Cotticelli MG, et al. 1996. The FHIT gene 3p14.2 is abnormal in lung cancer. Cell 17-26
-
(1996)
Cell
, pp. 17-26
-
-
Sozzi, G.1
Veronese, M.L.2
Negrini, M.3
Baffa, R.4
Cotticelli, M.G.5
-
145
-
-
0028072523
-
DNA Damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
-
Strasser A, Harris AW, Jacks T, Cory S. 1994. DNA Damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell 79:329-39
-
(1994)
Cell
, vol.79
, pp. 329-339
-
-
Strasser, A.1
Harris, A.W.2
Jacks, T.3
Cory, S.4
-
146
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su LK, Vogelstein B, Kinzler KW. 1993. Association of the APC tumor suppressor protein with catenins. Science 262:1734-37
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.K.1
Vogelstein, B.2
Kinzler, K.W.3
-
147
-
-
0028169994
-
p53- Dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, et al. 1994. p53- dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78:703-11
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
-
148
-
-
13344269668
-
The complete BRCA2 gene and mutations in chromosomal 13q-linked kindreds
-
Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, et al. 1996. The complete BRCA2 gene and mutations in chromosomal 13q-linked kindreds. Nat. Genet. 12:333-37
-
(1996)
Nat. Genet.
, vol.12
, pp. 333-337
-
-
Tavtigian, S.V.1
Simard, J.2
Rommens, J.3
Couch, F.4
Shattuck-Eidens, D.5
-
149
-
-
0027405720
-
A novel moresin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
-
Trofatter JA, MacCollin MM, Rutter JL, Murrell JR, Duyao MP, et al. 1993. A novel moresin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 72:791-800
-
(1993)
Cell
, vol.72
, pp. 791-800
-
-
Trofatter, J.A.1
MacCollin, M.M.2
Rutter, J.L.3
Murrell, J.R.4
Duyao, M.P.5
-
150
-
-
8044221266
-
Enhanced cell proliferative potential in culture of cells from p53-deficient mice
-
Tsukada T, Tomooka Y, Takai S, Ueda Y, Nishikawa S, et al. 1994. Enhanced cell proliferative potential in culture of cells from p53-deficient mice. Oncogene 9:603-9
-
(1994)
Oncogene
, vol.9
, pp. 603-609
-
-
Tsukada, T.1
Tomooka, Y.2
Takai, S.3
Ueda, Y.4
Nishikawa, S.5
-
151
-
-
0028902381
-
Functional interaction between E2F-4 and p130: Evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members
-
Vairo G, Livingston D, Ginsberg D. 1995. Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev. 9:869-81
-
(1995)
Genes Dev.
, vol.9
, pp. 869-881
-
-
Vairo, G.1
Livingston, D.2
Ginsberg, D.3
-
152
-
-
0028376386
-
Analysis of viral-host protein interactions and tumorigenesis in transgenic mice
-
Van Dyke TA. 1994. Analysis of viral-host protein interactions and tumorigenesis in transgenic mice. Semin. Can. Biol. 5:106.1-106.14
-
(1994)
Semin. Can. Biol.
, vol.5
, pp. 1061-10614
-
-
Van Dyke, T.A.1
-
153
-
-
0025609571
-
Tumorigenesis by slow-transforming retroviruses - An update
-
van Lohuizen M, Berns A. 1990. Tumorigenesis by slow-transforming retroviruses - an update. Biochim. Biophys. Acta 1032:213-35
-
(1990)
Biochim. Biophys. Acta
, vol.1032
, pp. 213-235
-
-
Van Lohuizen, M.1
Berns, A.2
-
154
-
-
0025863346
-
Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
-
van Lohuizen M, Verbeek S, Scheijen B, Wientjens E, van der Gulden H, Berns A. 1991. Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 65:737-52
-
(1991)
Cell
, vol.65
, pp. 737-752
-
-
Van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
Van Der Gulden, H.5
Berns, A.6
-
156
-
-
0029120950
-
Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons
-
Vogel KS, Brannan CI, Jenkins NA, Copeland NG, Parada LF. 1995. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Cell 82:733-42
-
(1995)
Cell
, vol.82
, pp. 733-742
-
-
Vogel, K.S.1
Brannan, C.I.2
Jenkins, N.A.3
Copeland, N.G.4
Parada, L.F.5
-
157
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-30
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
158
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White E. 1996. Life, death, and the pursuit of apoptosis. Genes Dev. 10:1-15
-
(1996)
Genes Dev.
, vol.10
, pp. 1-15
-
-
White, E.1
-
159
-
-
0029021621
-
Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity
-
Wienecke R, Konig A, DeClue JE. 1995. Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity. J Biol. Chem. 270:16409-14
-
(1995)
J Biol. Chem.
, vol.270
, pp. 16409-16414
-
-
Wienecke, R.1
Konig, A.2
DeClue, J.E.3
-
160
-
-
0028136594
-
Cooperative tumorigenic effects of germline mutations in Rb and p53
-
Williams BO, Remington L, Bronson RT, Mukai S, Albert DM, et al. 1994. Cooperative tumorigenic effects of germline mutations in Rb and p53. Nat. Genet. 7:480-84
-
(1994)
Nat. Genet.
, vol.7
, pp. 480-484
-
-
Williams, B.O.1
Remington, L.2
Bronson, R.T.3
Mukai, S.4
Albert, D.M.5
-
161
-
-
0027968207
-
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences
-
Williams BO, Schmitt EM, Remington L, Bronson RT, Albert DM, et al. 1994. Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences. EMBO J. 13:4251-59
-
(1994)
EMBO J.
, vol.13
, pp. 4251-4259
-
-
Williams, B.O.1
Schmitt, E.M.2
Remington, L.3
Bronson, R.T.4
Albert, D.M.5
-
162
-
-
0025057103
-
Retinoblastoma in transgenic mice
-
Windle JJ, Albert DA, O'Brien JM, Marcus DM, Disteche CM, et al. 1990. Retinoblastoma in transgenic mice. Nature 343:665-68
-
(1990)
Nature
, vol.343
, pp. 665-668
-
-
Windle, J.J.1
Albert, D.A.2
O'Brien, J.M.3
Marcus, D.M.4
Disteche, C.M.5
-
163
-
-
0021746318
-
Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene
-
Wolf D, Harris N, Rotter V. 1984. Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene. Cell 38:119-26
-
(1984)
Cell
, vol.38
, pp. 119-126
-
-
Wolf, D.1
Harris, N.2
Rotter, V.3
-
164
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancaster J, Swift S, Seal S, et al. 1995. Identification of the breast cancer susceptibility gene BRCA2. Nature 378:789-92
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
-
165
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
Wu X, Levine AJ. 1994. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91:3802-6
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3802-3806
-
-
Wu, X.1
Levine, A.J.2
-
166
-
-
0025244911
-
The catalytic domain of the neurofibromatosis type 1 gene product stimulatesras GTPase and complements ira mutants of S. cerevisiae
-
Xu G, Lin B, Tanaka K, Dunn D, Wood D, et al. 1990. The catalytic domain of the neurofibromatosis type 1 gene product stimulatesras GTPase and complements ira mutants of S. cerevisiae. Cell 63:835-41
-
(1990)
Cell
, vol.63
, pp. 835-841
-
-
Xu, G.1
Lin, B.2
Tanaka, K.3
Dunn, D.4
Wood, D.5
-
167
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
Yamasaki L, Bronson RT, Jacks T, Dyson N, Harlow E. 1996. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85:537-48
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Bronson, R.T.2
Jacks, T.3
Dyson, N.4
Harlow, E.5
-
168
-
-
0028849682
-
Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat
-
Yeung RS, Xiao GH, Everitt JI, Jin F, Walker CL. 1995. Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat. Mol. Carcinog. 14:28-36
-
(1995)
Mol. Carcinog.
, vol.14
, pp. 28-36
-
-
Yeung, R.S.1
Xiao, G.H.2
Everitt, J.I.3
Jin, F.4
Walker, C.L.5
-
169
-
-
0027996238
-
Predisposition to renal carcinoma in the Eker rat is determined by germline mutation of the tuberous sclerosis 2 (TSC2) gene
-
Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR, Knudson AG. 1994. Predisposition to renal carcinoma in the Eker rat is determined by germline mutation of the tuberous sclerosis 2 (TSC2) gene. Proc. Natl. Acad. Sci. USA 91:11413-16
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11413-11416
-
-
Yeung, R.S.1
Xiao, G.H.2
Jin, F.3
Lee, W.C.4
Testa, J.R.5
Knudson, A.G.6
-
170
-
-
0023775771
-
Altered expression of retinoblastoma (RB) gene in small-cell lung carcinoma of the lung
-
Yokota J, Akijama T, Funger Y-KT, Benedict WF, Namba Y, et al. 1988. Altered expression of retinoblastoma (RB) gene in small-cell lung carcinoma of the lung. Oncogene 3:471-75
-
(1988)
Oncogene
, vol.3
, pp. 471-475
-
-
Yokota, J.1
Akijama, T.2
Funger, Y.-K.T.3
Benedict, W.F.4
Namba, Y.5
-
171
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, et al. 1994. Sunburn and p53 in the onset of skin cancer. Nature 372:773-76
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
Simon, J.A.4
Sharma, H.W.5
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