Chapter 32. Pharmacogenomics and its Impact on Drug Design and Optimisation

Annual Reports in Medicinal Chemistry

Volumn 34, Issue C, 1999, Pages 339-348

  Bailey, David S ^a   Dean, Philip M ^b  

^a Incyte Pharmaceuticals ^*  (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001703538     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)60594-1     Document Type: Article

References (62)

1. Brown F.K. Ann. Rep. Med. Chem. 33 (1998) 375
2. Bailey D.S., Bondar A., and Furness L.M. Curr. Opin. Biotechnol. 9 (1998) 595
3. Drews J. Nature Biotechnol. 14 (1996) 1516
4. Salovyev V.V., and Salamov A.A. Nucl. Acids Res. 27 (1999) 248
5. Yeast genome information: http://genorne-www.stanford.edu/Saccharomyces/
6. Wilson R.K. Trends in Genetics 15 (1999) 51
7. Bottomley S. Drug Discovery Today 4 (1999) 42
8. Burks C. Nucl. Acids Res. 27 (1999) 1-9 and following articles
9. Thacker C., Marra M.A., Jones A., Baillie D.L., and Rose A.M. Genome Res. 9 (1999) 349
10. Whitney M., Rockenstein E., Cantin G., Knapp T., Zlokarnik G., Sanders P., Durick K., Craig F.F., and Negulescu P.A. Nature Biotechnol. 16 (1998) 1329
11. Elchebly M., Payette P., Michaliszyn E., Cromlish W., Collins S., Loy A.L., Normandin D., and Cheng A. J. Himms-Hagen, C-C. Chan, C. Ramachandran, M.J. Gresser, M. L. Tremblay and B. P. Kennedy, Science 283 (1999) 1544
12. Ferber D. Science 283 (1999) 1424
13. Wadman M. Nature 393 (1998) 399
14. Masood E. Nature 398 (1999) 545
15. Grahame-Smith D.G. Br. J. Clin. Pharmacol. 47 (1999) 7
16. Watson A., Mazumder A., Stewart M., and Balasubramanian S. Curr. Opin. Biotechnol. 9 (1998) 609
17. Khan J., Bittner M.L., Chen Y., Meltzer P.S., and Trent J.M. Biochim. Biophys. Acta 1423 (1999) M17
18. Iyer V.R., Eisen M.B., Ross D.T., Schuler G., Moore T., Lee J.C.F., Trent J.M., Staudt L.M., Huson J., Boguski M.S., Lashkari D., Shalon D., Botstein D., and Brown P.O. Science 283 (1999) 83
19. Tamayo P., Slonim D., Mesirov J., Zhu Q., Kitareewan S., Dmitrovsky E., Lander E.S., and Golub T.R. Proc. Natl. Acad. Sci. USA 96 (1999) 2907
20. Alizadeh A., Eisen M., Botstein D., Brown P.O., and Staudt L.M. J. Clin. Immunol. 18 (1998) 373
21. Jennings E.G., and Young R.A. Trends in Genetics 15 (1999) 202
22. Greller L.D., and Tobin F.L. Genome Res. 9 (1999) 282
23. Incyte Pharmaceuticals web site: http://lwww.incyte.com/
24. Affymetrix web site: http://www.affymetrix.com/
25. Research Genetics web site: http://www.researchgenetics.com/
26. Weinstein J.N., Myers T.G., O'Connor P.M., Friend S.H., Fornace A.J., Kohn K.W., Fojo T., Bates S.E., Rubinstein L.V., Anderson N.L., Buolamwini J.K., van Osdol W.W., Monks A.P., Scudiero D.A., Sausville E.A., Zaharevitz D.W., Bunow B., Viswanadhan V.N., Johnson G.S., Wittes R.E., and Paull K.D. Science 275 (1997) 343
27. Cho R.J., Campbell M.J., Winzeler E.A., Steinmetz L., Conway A., Wodicka L., Wolfsberg T.G., Gabrielian A.E., Landsman D., Lockhart D.J., and Davis R.W. Mol. Cell 2 (1998) 65
28. Gray N.S., Wodicka L., Thunnissen A.M., Norman T.C., Kwon S., Espinoza F.H., Morgan D.O., Barnes G., LeClerc S., Meijer L., Kim S.H., Lockhart D.J., and Schultz P.G. Science 281 (1998) 533
29. Saunders J., and Tarby C.M. Drug Discovery Today 4 (1999) 80
30. Transcription factor web sites: http://transfac.gbf.de/ and http://www.ifti.org/
31. Juge-Aubry C., Pernin A., Favez T., Burger A.G., Wahli W., Meier C.A., and Desvergne B. J. Biol. Chem. 272 (1997) 25252
32. Forman B.M., Chen J., and Evans R.M. Proc. Natl. Acad. Sci. USA 94 (1997) 4312
33. Nolte R.T., Wisely G.B., Westin S., Cobb J.E., Lambert M.H., Kurokawa R., Rosenfeld M.G., Willson T.M., Glass C.K., and Milburn M.V. Nature 395 (1998) 137
34. Westin S., Kurokawa R., Nolte R.T., Wisely G.B., Mclnerney E.M., Rose D.W., Milburn M.V., Rosenfeld M.G., and Glass C.K. Nature 395 (1998) 199
35. Henke B.R., Blanchard S.G., Brackeen M.F., Brown K.K., Cobb J.E., Collins J.L., Harrington Jr. W.W., Hashim M.A., Hull-Ryde E.A., Kaldor I., Kliewer S.A., Lake D.H., Leesnitzer L.M., Lehmann J.M., Lenhard J.M., Orband-Miller L.A., Miller J.F., Mook Jr. R.A., Noble S.A., Oliver Jr. W., Parks D.J., Plunket K.D., Szewczyk J.R., and Wilson T.M. J. Med. Chem. 41 (1998) 5020
36. Collins J.L., Blanchard S.G., Boswell G.E., Charifson P.S., Cobb J.E., Henke B.R., Hull-Ryde E.A., Kazmierski W.M., Lake D.H., Leesnitzer L.M., Lehmann J., Lenhard J.M., Orband-Miller L.A., Gray-Nunez Y., Parks D.J., Plunkett K.D., and Tong W.-Q. J. Med. Chem. 41 (1998) 5037
37. Cobb J.E., Blanchard S.G., Boswell E.G., Brown K.K., Charifson P.S., Cooper J.P., Collins J.L., Dezube M., Henke B.R., Hull-Ryde E.A., Lake D.H., Lenhard J.M., Oliver Jr. W., Oplinger J., Pentti M., Parks D.J., Plunket K.D., and Tong W.-Q. J. Med. Chem. 41 (1998) 5055
38. Berger J., Leibowitz M.D., Doebber T.W., Elbrecht A., Zhang B., Zhou G., Biswas C., Cullinan C.A., Hayes N.S., Li Y., Tanen M., Ventre J., Wu M.S., Berger G.D., Mosley R., Marquis R., Santini C., Sahoo S.P., Tolman R.L., Smith R.G., and Moller D.E. J. Biol. Chem. 274 (1999) 6718
39. Page M.J., Amess R., Rohlff C., Stubberfield C., and Parekh R. Drug Discovery Today 4 (1999) 55
40. Edgar A.D., Tomkiewicz C., Costet P., Legendre C., Aggerbeck M., Bouguet J., Staels B., Guyomard C., Pineau T., and Barouki R. Toxicol. Let. 98 (1998) 13
41. Plant N.J., Horley N.J., Savory R.L., Elcombe C.R., Gray T.J.B., and Bell D.R. Carcinogenesis 19 (1998) 925
42. Woodyatt N.J., Lambe K.G., Myers K.A., Tugwood J.D., and Roberts R.A. Carcinogenesis 20 (1999) 369
43. Barton G.J. Acta Cryst. D54 (1998) 1139
44. Hubbard T.J.P., Ailey B., Brenner S.E., Murzin A.G., and Chothia C. Acta Cryst. D54 (1998) 1147
45. Orengo C.A., Martin A.M., Hutchinson G., Jones S., Jones D.T., Michie A.D., Swindells M.B., and Thornton J.M. Acta Cryst. D54 (1998) 1155
46. Sowdhamini R., Burke D.F., Deane C., Huang J.-F., Mizuguchi K., Nagarajaram H.A., Overington J.P., Srinivasan N., Steward R.E., and Blundell T.L. Acta Cryst. D54 (1998) 1168
47. Weissig H., Shindyalov I.N., and Bourne P.E. Acta Cryst. D54 (1998) 1085
48. Hendlich M. Acta Cryst. D54 (1998) 1178
49. Sanchez R., and Sali A. Proc. Natl. Acad. Sci. USA 95 (1998) 13597
50. Fischer D., and Eisenberg D. Curr. Opin. Struct. Biol. 9 (1999) 208-211
51. Bohm H.-J. J. Comput. Aided Mol. Design 12 (1998) 309
52. Murray C.W., Auton T.R., and Eldridge M.D. J. Comput. Aided Mol. Design 12 (1998) 503
53. Willett P. J. Chem. Inf. Comput. Sci. 38 (1998) 983
54. Cramer R.D., Patterson D.E., Clark R.D., Soltanshahi F., and Lawless M.S. J. Chem. Inf. Comput. Sci. 38 (1998) 1010
55. Clark R.D., and Langton W.J. J. Chem. Inf. Comput. Sci. 38 (1998) 1079
56. Van Drie J.H., and Lajiness M.J. Drug Discovery Today 3 (1998) 274
57. Lewell X.Q., Judd D.B., Watson S.P., and Hann M.M. J. Chem. Inf. Comput. Sci. 38 (1998) 511
58. Smith D.A., and Jones B. Curr. Opin. in Drug Discovery and Development 2 (1999) 33
59. Buscher R., Herrmann V., and Insel P.A. Trends in Pharm. Sci. 20 (1999) 94
60. Lai E., Riley J., Purvis I., and Roses A. Genomics 54 (1998) 31
61. Schafer A.J., and Hawkins J.R. Nature Biotechnol. 16 (1998) 33
62. Housman D., and Ledley F.D. Nature Biotechnol. 16 (1998) 492