-
1
-
-
0027984902
-
Role of patient compliance in clinical pharmacokinetics
-
Urquhart J: Role of patient compliance in clinical pharmacokinetics. Clin Pharmacokin (1994) 27:202-215.
-
(1994)
Clin Pharmacokin
, vol.27
, pp. 202-215
-
-
Urquhart, J.1
-
2
-
-
33749710264
-
-
This paper introduces the concept of forgiveness' as an important parameter when considering variability in drug response.
-
This paper introduces the concept of forgiveness' as an important parameter when considering variability in drug response.
-
-
-
-
3
-
-
0342468147
-
Characterization and bioavallabllity of danazol-hydroxypropyl β-cyclodextrin coprecipitates
-
Ghorab MM, Adeyeye CM
-
Badawy SIF, Ghorab MM, Adeyeye CM: Characterization and bioavallabllity of danazol-hydroxypropyl β-cyclodextrin coprecipitates. IntJPharm (1996) 128:45-54.
-
(1996)
IntJPharm
, vol.128
, pp. 45-54
-
-
Badawy, S.I.F.1
-
4
-
-
0022402243
-
Sugimoto I: Physical properties of solid dispersions of poorly watersoluble drugs with enteric coating agents
-
Kawamura R, Nakagawa H.
-
Hasegawa A, Kawamura R, Nakagawa H. Sugimoto I: Physical properties of solid dispersions of poorly watersoluble drugs with enteric coating agents. Chem Pharm Bull (1985) 33:3429-3435.
-
(1985)
Chem Pharm Bull
, vol.33
, pp. 3429-3435
-
-
Hasegawa, A.1
-
5
-
-
0029996464
-
A physicochemical basis for the effect of food on the absolute oral bioavailability of Halofantrine
-
Porter CJH, Charman WN
-
Humberstone AJ, Porter CJH, Charman WN: A physicochemical basis for the effect of food on the absolute oral bioavailability of Halofantrine. J Pharm Sci (1996)85:525-529.
-
(1996)
J Pharm Sci
, vol.85
, pp. 525-529
-
-
Humberstone, A.J.1
-
6
-
-
0022548510
-
Slaughter RL: Pharmacokinetics of ketoconazole administered intravenously to dogs and orally as tablet and solution to humans and dogs
-
Brass C, Schentag JJ.
-
Baxter JG, Brass C, Schentag JJ. Slaughter RL: Pharmacokinetics of ketoconazole administered intravenously to dogs and orally as tablet and solution to humans and dogs. J Pharm Sc/(1986) 75:443-447.
-
(1986)
J Pharm Sc/
, vol.75
, pp. 443-447
-
-
Baxter, J.G.1
-
7
-
-
0017108613
-
Biopharmaceutical aspects of the absorption of orally administered nitrofurantoin
-
Tramp TFJ, Huizinga T
-
Moolenaar F, Tramp TFJ, Huizinga T: Biopharmaceutical aspects of the absorption of orally administered nitrofurantoin. Pharm Weekbl (1975) 111:1253-1264.
-
(1975)
Pharm Weekbl
, vol.111
, pp. 1253-1264
-
-
Moolenaar, F.1
-
8
-
-
0021185679
-
Phenytoin prodrugs III: Water-soluble prodrugs for oral and/or parenteral use
-
Schuller S, Sloan KB, Stella VJ
-
Varia SA, Schuller S, Sloan KB, Stella VJ: Phenytoin prodrugs III: Water-soluble prodrugs for oral and/or parenteral use. J Pharm Sei (1984) 73:1068-1073.
-
(1984)
J Pharm Sei
, vol.73
, pp. 1068-1073
-
-
Varia, S.A.1
-
9
-
-
0028269813
-
The application of solid dispersion technique with D-mannitol to the improvement in oral absorption of triamterene
-
Gines JM, Moyano JR, Rabasco AM
-
Arias MJ, Gines JM, Moyano JR, Rabasco AM: The application of solid dispersion technique with D-mannitol to the improvement in oral absorption of triamterene. J Drug Target (1994) 2:45-51.
-
(1994)
J Drug Target
, vol.2
, pp. 45-51
-
-
Arias, M.J.1
-
10
-
-
0031958251
-
Warhurst G, Gitford J, Walker D, Ayrton J, Eastmond R, Rowland M: Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides
-
Murby S.
-
He YL, Murby S. Warhurst G, Gitford J, Walker D, Ayrton J, Eastmond R, Rowland M: Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides. J Pharm Sei (1998) 87:626-633.
-
(1998)
J Pharm Sei
, vol.87
, pp. 626-633
-
-
He, Y.L.1
-
11
-
-
77953314801
-
Physiology of the gastrointestinal tract in relation to drug absorption
-
Smith SE: Physiology of the gastrointestinal tract in relation to drug absorption. Int Pharm J (I987) 1:101-104.
-
Int Pharm J I
, vol.987
, pp. 101-104
-
-
Smith, S.E.1
-
12
-
-
0018725622
-
Food-induced reduction in bioavaiiability of atenolol
-
Stenberg P, Uedholm H, Schersten B, WaahlinBoll E
-
Melander A, Stenberg P, Uedholm H, Schersten B, WaahlinBoll E: Food-induced reduction in bioavaiiability of atenolol. Eur J ClinPharmacol(1979) 16:327-330.
-
(1979)
Eur J ClinPharmacol
, vol.16
, pp. 327-330
-
-
Melander, A.1
-
13
-
-
0029865450
-
Design of drugs involving the concepts of theories of drug metabolism and pharmacokinetics
-
Jones BC, Walker DK
-
Smith, DA, Jones BC, Walker DK: Design of drugs involving the concepts of theories of drug metabolism and pharmacokinetics. Med Res Rev (1996) 16:243-266.
-
(1996)
Med Res Rev
, vol.16
, pp. 243-266
-
-
Smith, D.A.1
-
14
-
-
33749807331
-
-
This paper covers, in some depth, many of the concepts referred to in this review.
-
This paper covers, in some depth, many of the concepts referred to in this review.
-
-
-
-
15
-
-
33749747389
-
Variability in human pharmacokinetics in volunteer studies and in the clinical situation
-
Smith DA, Coates PE
-
Maclntyre F, Smith DA, Coates PE: Variability in human pharmacokinetics in volunteer studies and in the clinical situation. European conference on specificity and variability in drug metabolism, Besancon, France, May 10-12, 1995. Symposium proceedings.
-
(1995)
European Conference on Specificity and Variability in Drug Metabolism, Besancon, France, May 10-12
-
-
Maclntyre, F.1
-
16
-
-
33749700416
-
UK-84,149: A novel gut-selective spasmolytic with calcium antagonist activity
-
Alker D, Surges RA, Cross PE, Greengrass PM, Mclntyre P, Quinn P
-
Wallis RM, Alker D, Surges RA, Cross PE, Greengrass PM, Mclntyre P, Quinn P: UK-84,149: a novel gut-selective spasmolytic with calcium antagonist activity. Br J Pharmacol (I994) 112:574P.
-
Br J Pharmacol (I994)
, vol.112
-
-
Wallis, R.M.1
-
17
-
-
0026459382
-
Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes
-
Smith DA, Jones BC: Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes. Biochem Pharmacol (1992) 44:2089-2098.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 2089-2098
-
-
Smith, D.A.1
Jones, B.C.2
-
18
-
-
33749754448
-
-
This paper is a pivotal reference in the understanding of cytocnrome P450 substrate specificities.
-
This paper is a pivotal reference in the understanding of cytocnrome P450 substrate specificities.
-
-
-
-
19
-
-
0032444641
-
Human cytochrome P450s: Selectivity and measurement in vivo
-
Able SM, Hyland R, Jones BC: in press.
-
Smith DA, Able SM, Hyland R, Jones BC: Human cytochrome P450s: Selectivity and measurement in vivo. Xenobiotica (1998) in press.
-
(1998)
Xenobiotica
-
-
Smith, D.A.1
-
20
-
-
0031841377
-
Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
-
Miners JO, Birkett DJ: Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br J din Pharmacol(1998) 45:525-538.
-
(1998)
Br J Din Pharmacol
, vol.45
, pp. 525-538
-
-
Miners, J.O.1
Birkett, D.J.2
-
22
-
-
0025032064
-
Single- Vs multiple-dose pharmacokinetics of clozapine in psychiatric patients
-
Hsuan F, Honigfeld G, Robinson WT, Ereshelsky L, Crismon ML, Salelad SR, Hirschavitz J, Wagner R
-
Choc MG, Hsuan F, Honigfeld G, Robinson WT, Ereshelsky L, Crismon ML, Salelad SR, Hirschavitz J, Wagner R: Single- vs multiple-dose pharmacokinetics of clozapine in psychiatric patients. Pharm Res (1990) 7:347-351.
-
(1990)
Pharm Res
, vol.7
, pp. 347-351
-
-
Choc, M.G.1
-
23
-
-
0030868485
-
Genetic association between sensitivity to warfarin and expression of CYP2C9*3
-
Haining RL, Henné KR, Davis G, Rushmore TH, Trager WF, Rettie AE
-
Steward DJ, Haining RL, Henné KR, Davis G, Rushmore TH, Trager WF, Rettie AE: Genetic association between sensitivity to warfarin and expression of CYP2C9*3. Pharmacogenetics (1997) 7:361-367.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 361-367
-
-
Steward, D.J.1
-
24
-
-
0030721713
-
Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method
-
Merle Y, Mentré F, Mallet A
-
Jerting M, Merle Y, Mentré F, Mallet A: Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method. Br J Clin Pharmacol (1997) 44:447-453.
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 447-453
-
-
Jerting, M.1
-
25
-
-
0030656425
-
The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine
-
Engel G, Johansson l, Zanger UM, Bertilsson L
-
Eiermann B, Engel G, Johansson l, Zanger UM, Bertilsson L: The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine. Br J Clin Pharmacol (1997) 44:439-446.
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 439-446
-
-
Eiermann, B.1
-
27
-
-
33749748742
-
-
This paper emphasizes the reasons for variability in drug performance.
-
This paper emphasizes the reasons for variability in drug performance.
-
-
-
-
28
-
-
0031596301
-
2c. receptor polymorphisms and psychopathology in late onset Alzheimer's disease
-
Arranz MJ, Powell JF, Collier DA, Lovestone S
-
2c. receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Hum Mol Genet (1998) 7:1507-1509.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1507-1509
-
-
Holmes, C.1
-
29
-
-
0031466866
-
Association between genetic polymorphisms of the 2adrenoceptor and response to albuterol in children with and without a history of wheezing
-
Graves PE, Baldini M, Solomon S, Erickson R
-
Martinez FD, Graves PE, Baldini M, Solomon S, Erickson R: Association between genetic polymorphisms of the 2adrenoceptor and response to albuterol in children with and without a history of wheezing. J Clin Invest (1997) 100:3184-3188.
-
(1997)
J Clin Invest
, vol.100
, pp. 3184-3188
-
-
Martinez, F.D.1
-
30
-
-
0029841642
-
Sustained activation of a G protein-coupled receptor via 'anchored' agonist binding
-
Spasoff AP, Coleman RA, Johnson M, Liggett SB
-
Green SA, Spasoff AP, Coleman RA, Johnson M, Liggett SB: Sustained activation of a G protein-coupled receptor via 'anchored' agonist binding. Molecular localization of the salmeterol exosite within the ,-adrenergic receptor. J Biol Chem (1996) 271:24029-24035.
-
(1996)
Molecular Localization of the Salmeterol Exosite Within the ,-adrenergic Receptor. J Biol Chem
, vol.271
, pp. 24029-24035
-
-
Green, S.A.1
-
31
-
-
0023818954
-
2H] telenzepine to muscarinic acetylcholine receptors in calf forebrain
-
Auriga C, Kinder B, Birdsall NJM
-
2H] telenzepine to muscarinic acetylcholine receptors in calf forebrain. Eur J Pharmacol (1988) 145:87-90.
-
(1988)
Eur J Pharmacol
, vol.145
, pp. 87-90
-
-
Schudt, C.1
-
32
-
-
0026590432
-
Quantification of metoprolol beta2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamlc modeling
-
Jonkers RE, van Boxtel CJ
-
Braat MCP, Jonkers RE, van Boxtel CJ: Quantification of metoprolol beta2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamlc modeling. Pulm Pharmacol (1992) 5:31-38.
-
(1992)
Pulm Pharmacol
, vol.5
, pp. 31-38
-
-
Braat, M.C.P.1
|