Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans

Journal of Clinical Investigation

Volumn 114, Issue 8, 2004, Pages 1158-1164

  Srinivasan, Supriya ^a   Lubrano Berthelier, Cecile ^b   Govaerts, Cedric ^c   Picard, Franck ^b   Santiago, Pamela ^a   Conklin, Bruce R ^a   Vaisse, Christian ^b,d  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UCSF Diabetes Center   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; G PROTEIN COUPLED RECEPTOR; MELANOCORTIN 4 RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENERGY BALANCE; ENERGY TRANSFER; FOOD INTAKE; GENE FUNCTION; GENE MUTATION; HOMEOSTASIS; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL;

ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CYCLIC AMP; DRUG DESIGN; EATING; ENERGY METABOLISM; HOMEOSTASIS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; OBESITY; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RECEPTOR, MELANOCORTIN, TYPE 4; SECOND MESSENGER SYSTEMS; TRANS-ACTIVATION (GENETICS);

EID: 9644279627     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200421927     Document Type: Article

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