Integrin αv-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen

Journal of Cell Biology

Volumn 167, Issue 4, 2004, Pages 745-756

  Bao, Wenjie ^a   Strömblad, Staffan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD51 ANTIGEN; COLLAGEN GEL; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN P53; SMALL INTERFERING RNA; CASPASE; COLLAGEN; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DERMIS; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOMA; MELANOMA CELL; MICROENVIRONMENT; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CULTURE TECHNIQUE; DOWN REGULATION; DRUG ANTAGONISM; ENZYMOLOGY; EXPERIMENTAL MELANOMA; GENETICS; METABOLISM; METHODOLOGY; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; SKIN TUMOR; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; CASPASES; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN; DERMIS; DOWN-REGULATION; FEMALE; HUMANS; INTEGRIN ALPHAV; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 3; RNA INTERFERENCE; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 9444251067     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200404018     Document Type: Article

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