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Volumn 14, Issue 1, 2000, Pages 188-197

Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors

Author keywords

Apoptosis; gp130; IL 6; Myeloma; Proliferation

Indexed keywords

GLYCOPROTEIN GP 130; GROWTH FACTOR; INTERLEUKIN 6; MONOCLONAL ANTIBODY;

EID: 0033971174     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401632     Document Type: Article
Times cited : (57)

References (53)
  • 4
    • 0031001374 scopus 로고    scopus 로고
    • Experimental plasmacytomagenesis in mice
    • Potter M. Experimental plasmacytomagenesis in mice. Hematol Oncol Clin North Am 1997; 11: 323-347.
    • (1997) Hematol Oncol Clin North Am , vol.11 , pp. 323-347
    • Potter, M.1
  • 5
    • 0028921477 scopus 로고
    • Interleukin-6 in human multiple myeloma
    • Klein B, Zhang XG, Lu ZY, Bataille R. Interleukin-6 in human multiple myeloma. Blood 1995; 85: 863-872.
    • (1995) Blood , vol.85 , pp. 863-872
    • Klein, B.1    Zhang, X.G.2    Lu, Z.Y.3    Bataille, R.4
  • 7
    • 0031010127 scopus 로고    scopus 로고
    • Interleukin-6 overcomes p21WAF1 upregulation and G1 growth arrest induced by dexamethasone and interferon-gamma in multiple myeloma cells
    • Urashima M, Teoh G, Chauhan D, Hoshi Y, Ogata A, Treon SP, Schlossman RL, Anderson KG. Interleukin-6 overcomes p21WAF1 upregulation and G1 growth arrest induced by dexamethasone and interferon-gamma in multiple myeloma cells. Blood 1997; 90: 279-289.
    • (1997) Blood , vol.90 , pp. 279-289
    • Urashima, M.1    Teoh, G.2    Chauhan, D.3    Hoshi, Y.4    Ogata, A.5    Treon, S.P.6    Schlossman, R.L.7    Anderson, K.G.8
  • 10
    • 0024541066 scopus 로고
    • Establishment of two interleukin-6 (B cell stimulatory factor 2/interferonb2) dependent human bone marrow-derived myeloma cell lines
    • Shimizu S, Yoshioka R, Hirose Y, Susumu S, Tachibana J, Konda S. Establishment of two interleukin-6 (B cell stimulatory factor 2/interferonb2) dependent human bone marrow-derived myeloma cell lines. J Exp Med 1989; 169: 339-344.
    • (1989) J Exp Med , vol.169 , pp. 339-344
    • Shimizu, S.1    Yoshioka, R.2    Hirose, Y.3    Susumu, S.4    Tachibana, J.5    Konda, S.6
  • 12
    • 0029889061 scopus 로고    scopus 로고
    • Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6
    • Westendorf JJ, Ahmann G, Greipp PR, Witzig TE, Lust JA, Jelinek DF. Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6. Leukemia 1996; 10: 866-876.
    • (1996) Leukemia , vol.10 , pp. 866-876
    • Westendorf, J.J.1    Ahmann, G.2    Greipp, P.R.3    Witzig, T.E.4    Lust, J.A.5    Jelinek, D.F.6
  • 13
  • 14
    • 0028265160 scopus 로고
    • Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130
    • Zhang XG, Gu JJ, Lu ZY, Yasukawa K, Yancopoulos GD, Turner K, Shoyab M, Taga T, Kishimoto T, Bataille R, Kleir B. Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130. J Exp Med 1994; 179: 1337-1342.
    • (1994) J Exp Med , vol.179 , pp. 1337-1342
    • Zhang, X.G.1    Gu, J.J.2    Lu, Z.Y.3    Yasukawa, K.4    Yancopoulos, G.D.5    Turner, K.6    Shoyab, M.7    Taga, T.8    Kishimoto, T.9    Bataille, R.10    Kleir, B.11
  • 15
    • 0028344845 scopus 로고
    • Oncostatin M, leukemia inhibitory factor, and interleukin-6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130
    • Nishimoto N, Ogata A, Shima Y, Tani Y, Ogawa H, Nakagawa M, Sugiyama H, Yoshizaki K, Kishimoto T. Oncostatin M, leukemia inhibitory factor, and interleukin-6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130. J Exp Med 1994; 179: 1343-1347.
    • (1994) J Exp Med , vol.179 , pp. 1343-1347
    • Nishimoto, N.1    Ogata, A.2    Shima, Y.3    Tani, Y.4    Ogawa, H.5    Nakagawa, M.6    Sugiyama, H.7    Yoshizaki, K.8    Kishimoto, T.9
  • 17
    • 0030266773 scopus 로고    scopus 로고
    • Growth regulatory pathways in myeloma. Evidence of autocrine oncostatin M expression
    • Westendorf JJ, Jelinek DF. Growth regulatory pathways in myeloma. Evidence of autocrine oncostatin M expression. J Immunol 1996; 157: 3081-3088.
    • (1996) J Immunol , vol.157 , pp. 3081-3088
    • Westendorf, J.J.1    Jelinek, D.F.2
  • 18
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin CH. Dimerization of cell surface receptors in signal transduction. Cell 1995; 80: 213-223.
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 19
    • 12644294970 scopus 로고    scopus 로고
    • Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation
    • Mosley B, De Imus C, Friend D, Boiani N, Thoma B, Park LS, Cosman D. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. J Biol Chem 1996; 271: 32635-32643.
    • (1996) J Biol Chem , vol.271 , pp. 32635-32643
    • Mosley, B.1    De Imus, C.2    Friend, D.3    Boiani, N.4    Thoma, B.5    Park, L.S.6    Cosman, D.7
  • 20
    • 0028064835 scopus 로고
    • High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130
    • Ward LD, Howlelt GJ, Discolo G, Yasukawa K, Hammacher A, Moritz RL, Simpson RJ. High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130. J Biol Chem 1994; 269: 23286-23289.
    • (1994) J Biol Chem , vol.269 , pp. 23286-23289
    • Ward, L.D.1    Howlelt, G.J.2    Discolo, G.3    Yasukawa, K.4    Hammacher, A.5    Moritz, R.L.6    Simpson, R.J.7
  • 21
    • 16944364509 scopus 로고    scopus 로고
    • Establishment and characterization of a human stroma-depenclent myeloma cell line (MM5.1) and its stroma-independent variant (MM5.2)
    • Van Riet I, De Greet C, Aharchi F, Woischwill C, De Waele M, Bakkus M, Lacor P, Schots R, Van Camp B. Establishment and characterization of a human stroma-depenclent myeloma cell line (MM5.1) and its stroma-independent variant (MM5.2) Leukemia 1997; 11: 284-293.
    • (1997) Leukemia , vol.11 , pp. 284-293
    • Van Riet, I.1    De Greet, C.2    Aharchi, F.3    Woischwill, C.4    De Waele, M.5    Bakkus, M.6    Lacor, P.7    Schots, R.8    Van Camp, B.9
  • 22
    • 0031983022 scopus 로고    scopus 로고
    • Long-term bone marrow cultured stromal cells regulate myeloma tumour growth in vitro: Studies with primary tumour cells and LTBMC-dependent cell lines
    • Bloem AC, Lamme T, de Smet M, Kok H, Vooijs W, Wijdenes J, Boom SE, Lokhorst HM. Long-term bone marrow cultured stromal cells regulate myeloma tumour growth in vitro: studies with primary tumour cells and LTBMC-dependent cell lines. Br J Haematol 1998; 100: 166-175.
    • (1998) Br J Haematol , vol.100 , pp. 166-175
    • Bloem, A.C.1    Lamme, T.2    De Smet, M.3    Kok, H.4    Vooijs, W.5    Wijdenes, J.6    Boom, S.E.7    Lokhorst, H.M.8
  • 23
    • 0029914433 scopus 로고    scopus 로고
    • Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M
    • Gu ZJ, Wijdenes J, Zhang XG, Hallet MM, Clement C, Klein B. Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M. J Immunol Meth 1996; 190: 21-27.
    • (1996) J Immunol Meth , vol.190 , pp. 21-27
    • Gu, Z.J.1    Wijdenes, J.2    Zhang, X.G.3    Hallet, M.M.4    Clement, C.5    Klein, B.6
  • 24
    • 0029617757 scopus 로고
    • Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies
    • Wijdenes J, Heinrich PC, Muller-Newen G, Roche C, Gu ZJ, Clement C, Klein B. Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies. Eur J Immunol 1995; 25: 3474-3481.
    • (1995) Eur J Immunol , vol.25 , pp. 3474-3481
    • Wijdenes, J.1    Heinrich, P.C.2    Muller-Newen, G.3    Roche, C.4    Gu, Z.J.5    Clement, C.6    Klein, B.7
  • 25
    • 0024832002 scopus 로고
    • Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias
    • Bataille R, Jourdan M, Zhang XG, Klein B. Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias. J Clin Invest 1989; 84: 2008-2011.
    • (1989) J Clin Invest , vol.84 , pp. 2008-2011
    • Bataille, R.1    Jourdan, M.2    Zhang, X.G.3    Klein, B.4
  • 26
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Meth 1995; 184: 39-51.
    • (1995) J Immunol Meth , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 30
    • 0001857475 scopus 로고    scopus 로고
    • Cytokines, cylokine receptors and signal transduction in human multiple myeloma
    • Malpas JS, Bergsage DE, Kyle RA, Anderson KC (eds). Oxford University Press: Oxford
    • Klein B, Zhang XG, Rossi JF. Cytokines, cylokine receptors and signal transduction in human multiple myeloma. In: Malpas JS, Bergsage DE, Kyle RA, Anderson KC (eds). Myeloma: Biology and Management. Oxford University Press: Oxford, 1998, pp 70-88.
    • (1998) Myeloma: Biology and Management , pp. 70-88
    • Klein, B.1    Zhang, X.G.2    Rossi, J.F.3
  • 31
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T, Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 1997; 15: 797-819.
    • (1997) Annu Rev Immunol , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 32
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • Fukada T, Hibi M, Yamanaka Y, Takahashi-Tezuka M, Fujitan Y, Yamaguchi T, Nakajima K, Hirano T. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity 1996; 5: 449-460.
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitan, Y.5    Yamaguchi, T.6    Nakajima, K.7    Hirano, T.8
  • 34
    • 0029124138 scopus 로고
    • Introduction of an activated N-ras oncogene alters the growth characteristics of the interlenkin 6-dependent myeloma cell line ANBL6
    • Billadeau D, Jelinek DF, Shah N, LeBien TW, Van Ness B. Introduction of an activated N-ras oncogene alters the growth characteristics of the interlenkin 6-dependent myeloma cell line ANBL6. Cancer Res 1995; 55: 3640-3646.
    • (1995) Cancer Res , vol.55 , pp. 3640-3646
    • Billadeau, D.1    Jelinek, D.F.2    Shah, N.3    LeBien, T.W.4    Van Ness, B.5
  • 35
    • 0030049565 scopus 로고    scopus 로고
    • Inlerleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1
    • Neumann C, Zehentmaier G, Danhauser-Riedl S, Emmerich B, Hallek M. Inlerleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1. Eur J Immunol 1996; 26: 379-384.
    • (1996) Eur J Immunol , vol.26 , pp. 379-384
    • Neumann, C.1    Zehentmaier, G.2    Danhauser-Riedl, S.3    Emmerich, B.4    Hallek, M.5
  • 37
    • 0031985198 scopus 로고    scopus 로고
    • Multiple myeloma: Increasing evidence for a multistep transformation process
    • Hallek M, Leif BP, Anderson KC. Multiple myeloma: increasing evidence for a multistep transformation process. Blood 1998; 91: 3-21.
    • (1998) Blood , vol.91 , pp. 3-21
    • Hallek, M.1    Leif, B.P.2    Anderson, K.C.3
  • 38
    • 0031181228 scopus 로고    scopus 로고
    • A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth
    • Jelinek DF, Witzig TE, Arendt BK. A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth. J Immunol 1997; 159: 487-496.
    • (1997) J Immunol , vol.159 , pp. 487-496
    • Jelinek, D.F.1    Witzig, T.E.2    Arendt, B.K.3
  • 39
    • 0032530360 scopus 로고    scopus 로고
    • IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis
    • Ferlin-Bozombes M, Jourdan M, Liautard J, Brochier J, Rossi JF, Klein B. IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis. J Immunol 1998; 161: 2692-2699.
    • (1998) J Immunol , vol.161 , pp. 2692-2699
    • Ferlin-Bozombes, M.1    Jourdan, M.2    Liautard, J.3    Brochier, J.4    Rossi, J.F.5    Klein, B.6
  • 41
    • 0030922231 scopus 로고    scopus 로고
    • Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
    • Chesi M, Nardini E, Brents LA, Schrock E, Ried T, Kuehl WM, Bergsagel PL. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet 1997; 16: 260-264.
    • (1997) Nat Genet , vol.16 , pp. 260-264
    • Chesi, M.1    Nardini, E.2    Brents, L.A.3    Schrock, E.4    Ried, T.5    Kuehl, W.M.6    Bergsagel, P.L.7
  • 42
    • 0030660196 scopus 로고    scopus 로고
    • Syndecans: Multifunctional cell-surface co-receplors
    • Carey DJ. Syndecans: multifunctional cell-surface co-receplors. Biochem J 1997; 327: 1-16.
    • (1997) Biochem J , vol.327 , pp. 1-16
    • Carey, D.J.1
  • 43
    • 0029118548 scopus 로고
    • Adhesion molecules on human myeloma cells: Significant changes in expression related to malignancy, tumor spreading, and immortalization
    • Pellat-Deceunynck C, Barille S, Puthier D, Rapp MJ, Harousseau JL, Bataille K, Amiot M. Adhesion molecules on human myeloma cells: significant changes in expression related to malignancy, tumor spreading, and immortalization. Cancer Res 1995; 55: 3647-3653.
    • (1995) Cancer Res , vol.55 , pp. 3647-3653
    • Pellat-Deceunynck, C.1    Barille, S.2    Puthier, D.3    Rapp, M.J.4    Harousseau, J.L.5    Bataille, K.6    Amiot, M.7
  • 46
    • 0030964277 scopus 로고    scopus 로고
    • The biology of replicative senescence
    • Campisi J. The biology of replicative senescence. Eur J Cancer 1997; 33: 703-709.
    • (1997) Eur J Cancer , vol.33 , pp. 703-709
    • Campisi, J.1
  • 47
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of human fibroblasts induced by oncogenic Raf
    • Zhu J, Woods D, McMahon M, Bishop JM. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev 1998; 12: 2997-3007.
    • (1998) Genes Dev , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4
  • 53
    • 0027303256 scopus 로고
    • Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding
    • van Dam M, Mullberg J, Schooltink H, Stoyan T, Brakenhoff JP, Graeve L, Heinrich PC, Rose-John S. Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. J Biol Chem 1993; 268: 15285-15290.
    • (1993) J Biol Chem , vol.268 , pp. 15285-15290
    • Van Dam, M.1    Mullberg, J.2    Schooltink, H.3    Stoyan, T.4    Brakenhoff, J.P.5    Graeve, L.6    Heinrich, P.C.7    Rose-John, S.8


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