Regulation of stress-induced cytokine production by pyridinylimidazoles inhibition of CSBP kinase

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 1, 1997, Pages 49-64

  Gallagher, Timothy F ^a   Seibel, George L ^a   Kassis, Shouki ^a   Laydon, Jeffrey T ^a   Blumenthal, Mary Jane ^a   Lee, John C ^a   Lee, Dennis ^a   Boehm, Jeffrey C ^a   Fier Thompson, Susan M ^a   Abt, Jeffrey W ^a   Soreson, Margaret E ^a   Smietana, Juanita M ^a   Hall, Ralph F ^a   Garigipati, Ravi S ^a   Bender, Paul E ^a   Erhard, Karl F ^a   Krog, Arnold J ^a   Hofmann, Glenn A ^a   Sheldrake, Peter L ^a   McDonnell, Peter C ^a   Kumar, Sanjay ^a   Young, Peter R ^a   Adams, Jerry L ^a   more..

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 FLUOROPHENYL) 2,3 DIHYDRO 5 (4 PYRIDYL)IMIDAZO[2,1 B]THIAZOLE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE C; SYNAPTOPHYSIN;

BINDING AFFINITY; CONFERENCE PAPER; ENZYME BINDING; ENZYME INHIBITION; GENE EXPRESSION REGULATION; MOLECULAR MODEL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SIGNAL TRANSDUCTION; STRESS;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; STRESS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17644437502     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(96)00212-X     Document Type: Conference Paper

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