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Volumn , Issue , 2015, Pages 1-29

Application of the Neurosphere Assay for DNT Hazard Assessment: Challenges and Limitations

Author keywords

Brain development; Developmental neurotoxicity; Human; In vitro; Mouse; Neural progenitor cell; Rat; Species differences

Indexed keywords


EID: 85144885421     PISSN: 15572153     EISSN: 19406053     Source Type: Book Series    
DOI: 10.1007/7653_2015_49     Document Type: Chapter
Times cited : (19)

References (112)
  • 1
    • 0033752284 scopus 로고    scopus 로고
    • Neural science: a century of progress and the mysteries that remain
    • Albright TD, Jessell TM, Kandel ER, Posner MI (2000) Neural science: a century of progress and the mysteries that remain. Neuron 25 (1):S1–S55
    • (2000) Neuron , vol.25 , Issue.1 , pp. S1-S55
    • Albright, T.D.1    Jessell, T.M.2    Kandel, E.R.3    Posner, M.I.4
  • 3
    • 0036272896 scopus 로고    scopus 로고
    • Induction of the neural crest: A multigene process
    • Knecht AK, Bronner-Fraser M (2002) Induction of the neural crest: a multigene process. Nat Rev Genet 3(6):453–461
    • (2002) Nat Rev Genet , vol.3 , Issue.6 , pp. 453-461
    • Knecht, A.K.1    Bronner-Fraser, M.2
  • 5
    • 0038407848 scopus 로고    scopus 로고
    • Trajectories of brain development: Point of vulnerability or window of opportunity?
    • Andersen SL (2003) Trajectories of brain development: point of vulnerability or window of opportunity? Neurosci Biobehav Rev 27(1):3–18
    • (2003) Neurosci Biobehav Rev , vol.27 , Issue.1 , pp. 3-18
    • Andersen, S.L.1
  • 7
    • 0028786105 scopus 로고
    • Developing brain as a target of toxicity
    • Rodier PM (1995) Developing brain as a target of toxicity. Environ Health Perspect 103 (Suppl 6):73–76
    • (1995) Environ Health Perspect , vol.103 , pp. 73-76
    • Rodier, P.M.1
  • 8
    • 39349118236 scopus 로고    scopus 로고
    • Transforming environmental health protection
    • Collins FS, Gray GM, Bucher JR (2008) Transforming environmental health protection. Science 319(5865):906–907
    • (2008) Science , vol.319 , Issue.5865 , pp. 906-907
    • Collins, F.S.1    Gray, G.M.2    Bucher, J.R.3
  • 9
    • 84863835842 scopus 로고    scopus 로고
    • Automated neurosphere sorting and plating by the COPAS large particle sorter is a suitable method for high-throughput 3D in vitro applications
    • Gassmann K, Baumann J, Giersiefer S, Schuwald J, Schreiber T, Merk H, Fritsche E (2012) Automated neurosphere sorting and plating by the COPAS large particle sorter is a suitable method for high-throughput 3D in vitro applications. Toxicol in Vitro 26 (6):993–1000
    • (2012) Toxicol in Vitro , vol.26 , Issue.6 , pp. 993-1000
    • Gassmann, K.1    Baumann, J.2    Giersiefer, S.3    Schuwald, J.4    Schreiber, T.5    Merk, H.6    Fritsche, E.7
  • 10
    • 84871716691 scopus 로고    scopus 로고
    • Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells
    • Culbreth ME, Harrill JA, Freudenrich TM, Mundy WR, Shafer TJ (2012) Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells. Neurotoxicology 33 (6):1499–1510
    • (2012) Neurotoxicology , vol.33 , Issue.6 , pp. 1499-1510
    • Culbreth, M.E.1    Harrill, J.A.2    Freudenrich, T.M.3    Mundy, W.R.4    Shafer, T.J.5
  • 11
    • 80855131654 scopus 로고    scopus 로고
    • Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth
    • Harrill JA, Freudenrich TM, Robinette BL, Mundy WR (2011) Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth. Toxicol Appl Pharmacol 256 (3):268–280
    • (2011) Toxicol Appl Pharmacol , vol.256 , Issue.3 , pp. 268-280
    • Harrill, J.A.1    Freudenrich, T.M.2    Robinette, B.L.3    Mundy, W.R.4
  • 12
    • 73849133701 scopus 로고    scopus 로고
    • Comparison of PC12 and cerebellar granule cell cultures for evaluating neurite outgrowth using high content analysis
    • Radio NM, Freudenrich TM, Robinette BL, Crofton KM, Mundy WR (2010) Comparison of PC12 and cerebellar granule cell cultures for evaluating neurite outgrowth using high content analysis. Neurotoxicol Teratol 32(1):25–35
    • (2010) Neurotoxicol Teratol , vol.32 , Issue.1 , pp. 25-35
    • Radio, N.M.1    Freudenrich, T.M.2    Robinette, B.L.3    Crofton, K.M.4    Mundy, W.R.5
  • 13
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman E, Pankov R, Stevens DR, Yamada KM (2001) Taking cell-matrix adhesions to the third dimension. Science 294 (5547):1708–1712
    • (2001) Science , vol.294 , Issue.5547 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 14
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • Yamada KM, Cukierman E (2007) Modeling tissue morphogenesis and cancer in 3D. Cell 130(4):601–610
    • (2007) Cell , vol.130 , Issue.4 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 16
    • 80055052200 scopus 로고    scopus 로고
    • Neural cell 3D microtissue formation is marked by cytokines’ up-regulation
    • Lai Y, Asthana A, Cheng K, Kisaalita WS (2011) Neural cell 3D microtissue formation is marked by cytokines’ up-regulation. PLoS One 6(10):e26821
    • (2011) Plos One , vol.6 , Issue.10
    • Lai, Y.1    Asthana, A.2    Cheng, K.3    Kisaalita, W.S.4
  • 17
    • 0026705290 scopus 로고
    • Study design considerations in developmental neurotoxicology
    • Tilson HA (1992) Study design considerations in developmental neurotoxicology. Neurotoxicol Teratol 14(3):199–203
    • (1992) Neurotoxicol Teratol , vol.14 , Issue.3 , pp. 199-203
    • Tilson, H.A.1
  • 18
    • 0035047581 scopus 로고    scopus 로고
    • Methods to identify and characterize developmental neurotoxicity for human health risk assessment: Overview
    • Mileson BE, Ferenc SA (2001) Methods to identify and characterize developmental neurotoxicity for human health risk assessment: overview. Environ Health Perspect 109(Suppl 1):77–78
    • (2001) Environ Health Perspect , vol.109 , pp. 77-78
    • Mileson, B.E.1    Ferenc, S.A.2
  • 19
    • 18244412478 scopus 로고    scopus 로고
    • Current status of developmental neurotoxicity: Regulatory view
    • Hass U (2003) Current status of developmental neurotoxicity: regulatory view. Toxicol Lett 140:155–159
    • (2003) Toxicol Lett , vol.140 , pp. 155-159
    • Hass, U.1
  • 20
    • 18244429701 scopus 로고    scopus 로고
    • Current status of developmental neurotoxicity: An industry perspective
    • Kaufmann W (2003) Current status of developmental neurotoxicity: an industry perspective. Toxicol Lett 140:161–169
    • (2003) Toxicol Lett , vol.140 , pp. 161-169
    • Kaufmann, W.1
  • 21
    • 33750608522 scopus 로고    scopus 로고
    • Lessons from TGN1412
    • Hanke T (2006) Lessons from TGN1412. Lancet 368(9547):1569–1570
    • (2006) Lancet , vol.368 , Issue.9547 , pp. 1569-1570
    • Hanke, T.1
  • 22
    • 84876685425 scopus 로고    scopus 로고
    • Inflammatory findings on species extrapolations: Humans are definitely no 70-kg mice
    • Leist M, Hartung T (2013) Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice. Arch Toxicol 87(4):563–567
    • (2013) Arch Toxicol , vol.87 , Issue.4 , pp. 563-567
    • Leist, M.1    Hartung, T.2
  • 23
    • 85144867151 scopus 로고    scopus 로고
    • Bal-Price A, Crofton, Kevin M., Shafer, Timothy, Sachana, Magdalini, Behl, Mamta, Forsby, Anna, Hargreaves, Alan, Landesmann, Brigitte, Lein, Pamela J., Louisse, Jochem, Monnet-Tschudi, Florianne, Paini, Alicia, Rolaki, Alexandra, Schrattenholz, André, Suñol, Cristina, van Thriel, Christoph, Whelan, Maurice, Fritsche, Ellen (2014) Workshop report: Adverse Outcome Pathways (AOP) relevant to neurotoxicity. (in press)
    • Bal-Price A, Crofton, Kevin M., Shafer, Timothy, Sachana, Magdalini, Behl, Mamta, Forsby, Anna, Hargreaves, Alan, Landesmann, Brigitte, Lein, Pamela J., Louisse, Jochem, Monnet-Tschudi, Florianne, Paini, Alicia, Rolaki, Alexandra, Schrattenholz, André, Suñol, Cristina, van Thriel, Christoph, Whelan, Maurice, Fritsche, Ellen (2014) Workshop report: Adverse Outcome Pathways (AOP) relevant to neurotoxicity. (in press)
  • 24
    • 84901820244 scopus 로고    scopus 로고
    • International STakeholder NETwork (ISTNET) for Creating a Developmental Neurotoxicity Testing (DNT) roadmap for regulatory purposes
    • Crofton K, Fritsche E, Ylikomi T, Bal-Price A (2014) International STakeholder NETwork (ISTNET) for Creating a Developmental Neurotoxicity Testing (DNT) roadmap for regulatory purposes. ALTEX 31 (2):223–224
    • (2014) ALTEX , vol.31 , Issue.2 , pp. 223-224
    • Crofton, K.1    Fritsche, E.2    Ylikomi, T.3    Bal-Price, A.4
  • 25
    • 84865560583 scopus 로고    scopus 로고
    • Developmental neurotoxicity testing: A path forward
    • Crofton KM, Mundy WR, Shafer TJ (2012) Developmental neurotoxicity testing: a path forward. Congenit Anom (Kyoto) 52 (3):140–146
    • (2012) Congenit Anom (Kyoto) , vol.52 , Issue.3 , pp. 140-146
    • Crofton, K.M.1    Mundy, W.R.2    Shafer, T.J.3
  • 26
    • 85003798485 scopus 로고    scopus 로고
    • Scientific opinion on the identification of pesticides to be included in cumulative assessment groups on the basis of their toxicological profile
    • EFSA (2013) Scientific opinion on the identification of pesticides to be included in cumulative assessment groups on the basis of their toxicological profile. EFSA J 11(7)
    • (2013) EFSA J , vol.11 , Issue.7
  • 28
    • 33746266489 scopus 로고    scopus 로고
    • A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: Implications for the neuropathology of schizophrenia
    • Moore H, Jentsch JD, Ghajarnia M, Geyer MA, Grace AA (2006) A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biol Psychiatry 60(3):253–264
    • (2006) Biol Psychiatry , vol.60 , Issue.3 , pp. 253-264
    • Moore, H.1    Jentsch, J.D.2    Ghajarnia, M.3    Geyer, M.A.4    Grace, A.A.5
  • 29
    • 85144830663 scopus 로고    scopus 로고
    • Baumann J, Barenys M, Gassmann K, Fritsche E (2014) Comparative human and rat “neurosphere assay” for developmental neurotoxicity testing. Curr Protoc Toxicol 59:12.21.1–12.21.24
    • Baumann J, Barenys M, Gassmann K, Fritsche E (2014) Comparative human and rat “neurosphere assay” for developmental neurotoxicity testing. Curr Protoc Toxicol 59:12.21.1–12.21.24
  • 30
    • 0026526516 scopus 로고
    • A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds BA, Tetzlaff W, Weiss S (1992) A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci 12(11):4565–4574
    • (1992) J Neurosci , vol.12 , Issue.11 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 31
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGFresponsive mammalian embryonic CNS precursor is a stem cell
    • Reynolds BA, Weiss S (1996) Clonal and population analyses demonstrate that an EGFresponsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 175(1):1–13
    • (1996) Dev Biol , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 32
    • 0028819519 scopus 로고
    • Increased survival of rat EGFgenerated CNS precursor cells using B27 supplemented medium
    • Svendsen C, Fawcett J, Bentlage C, Dunnett S (1995) Increased survival of rat EGFgenerated CNS precursor cells using B27 supplemented medium. Exp Brain Res 102 (3):407–414
    • (1995) Exp Brain Res , vol.102 , Issue.3 , pp. 407-414
    • Svendsen, C.1    Fawcett, J.2    Bentlage, C.3    Dunnett, S.4
  • 36
    • 33845424655 scopus 로고    scopus 로고
    • Developmental neurotoxicity of industrial chemicals
    • Grandjean P, Landrigan PJ (2006) Developmental neurotoxicity of industrial chemicals. Lancet 368(9553):2167–2178
    • (2006) Lancet , vol.368 , Issue.9553 , pp. 2167-2178
    • Grandjean, P.1    Landrigan, P.J.2
  • 37
    • 84894029844 scopus 로고    scopus 로고
    • Neurobehavioural effects of developmental toxicity
    • Grandjean P, Landrigan PJ (2014) Neurobehavioural effects of developmental toxicity. Lancet Neurol 13(3):330–338
    • (2014) Lancet Neurol , vol.13 , Issue.3 , pp. 330-338
    • Grandjean, P.1    Landrigan, P.J.2
  • 38
    • 84869465982 scopus 로고    scopus 로고
    • Inherited effects of lowdose exposure to methylmercury in neural stem cells
    • Bose R, Onishchenko N, Edoff K, Lang AMJ, Ceccatelli S (2012) Inherited effects of lowdose exposure to methylmercury in neural stem cells. Toxicol Sci 130:383–390
    • (2012) Toxicol Sci , vol.130 , pp. 383-390
    • Bose, R.1    Onishchenko, N.2    Edoff, K.3    Lang, A.M.J.4    Ceccatelli, S.5
  • 39
    • 33751508327 scopus 로고    scopus 로고
    • Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E
    • Burke K, Cheng Y, Li B, Petrov A, Joshi P, Berman RF, Reuhl KR, DiCicco-Bloom E (2006) Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E. Neurotoxicology 27(6):970–981
    • (2006) Neurotoxicology , vol.27 , Issue.6 , pp. 970-981
    • Burke, K.1    Cheng, Y.2    Li, B.3    Petrov, A.4    Joshi, P.5    Berman, R.F.6    Reuhl, K.R.7    Dicicco-Bloom, E.8
  • 42
    • 67349218856 scopus 로고    scopus 로고
    • Valproic acid in pregnancy: How much are we endangering the embryo and fetus?
    • Ornoy A (2009) Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reprod Toxicol 28(1):1–10
    • (2009) Reprod Toxicol , vol.28 , Issue.1 , pp. 1-10
    • Ornoy, A.1
  • 43
    • 35248894933 scopus 로고    scopus 로고
    • The mechanisms of action of valproate in neuropsychiatric disorders: Can we see the forest for the trees?
    • Rosenberg G (2007) The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci 64(16):2090–2103
    • (2007) Cell Mol Life Sci , vol.64 , Issue.16 , pp. 2090-2103
    • Rosenberg, G.1
  • 44
    • 84865268274 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK3beta/beta-catenin pathway
    • Go HS, Kim KC, Choi CS, Jeon SJ, Kwon KJ, Han SH, Lee J, Cheong JH, Ryu JH, Kim CH, Ko KH, Shin CY (2012) Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK3beta/beta-catenin pathway. Neuropharmacology 63(6):1028–1041
    • (2012) Neuropharmacology , vol.63 , Issue.6 , pp. 1028-1041
    • Go, H.S.1    Kim, K.C.2    Choi, C.S.3    Jeon, S.J.4    Kwon, K.J.5    Han, S.H.6    Lee, J.7    Cheong, J.H.8    Ryu, J.H.9    Kim, C.H.10    Ko, K.H.11    Shin, C.Y.12
  • 45
    • 84880039835 scopus 로고    scopus 로고
    • HDAC inhibitors dysregulate neural stem cell activity in the postnatal mouse brain
    • Foti SB, Chou A, Moll AD, Roskams AJ (2013) HDAC inhibitors dysregulate neural stem cell activity in the postnatal mouse brain. Int J Dev Neurosci 31(6):434–447
    • (2013) Int J Dev Neurosci , vol.31 , Issue.6 , pp. 434-447
    • Foti, S.B.1    Chou, A.2    Moll, A.D.3    Roskams, A.J.4
  • 46
    • 32144433872 scopus 로고    scopus 로고
    • A developmental and genetic classification for malformations of cortical development
    • Barkovich A, Kuzniecky R, Jackson G, Guerrini R, Dobyns W (2005) A developmental and genetic classification for malformations of cortical development. Neurology 65 (12):1873–1887
    • (2005) Neurology , vol.65 , Issue.12 , pp. 1873-1887
    • Barkovich, A.1    Kuzniecky, R.2    Jackson, G.3    Guerrini, R.4    Dobyns, W.5
  • 47
    • 78650033884 scopus 로고    scopus 로고
    • Increased interstitial white matter neuron density in the dorsolateral prefrontal cortex of people with schizophrenia
    • Yang Y, Fung SJ, Rothwell A, Tianmei S, Weickert CS (2011) Increased interstitial white matter neuron density in the dorsolateral prefrontal cortex of people with schizophrenia. Biol Psychiatry 69(1):63–70
    • (2011) Biol Psychiatry , vol.69 , Issue.1 , pp. 63-70
    • Yang, Y.1    Fung, S.J.2    Rothwell, A.3    Tianmei, S.4    Weickert, C.S.5
  • 49
  • 50
    • 34247893688 scopus 로고    scopus 로고
    • ERK-dependent and-independent pathways trigger human neural progenitor cell migration
    • Moors M, Cline JE, Abel J, Fritsche E (2007) ERK-dependent and-independent pathways trigger human neural progenitor cell migration. Toxicol Appl Pharmacol 221(1):57–67
    • (2007) Toxicol Appl Pharmacol , vol.221 , Issue.1 , pp. 57-67
    • Moors, M.1    Cline, J.E.2    Abel, J.3    Fritsche, E.4
  • 51
    • 7944236785 scopus 로고    scopus 로고
    • Src family kinases, key regulators of signal transduction
    • Parsons SJ, Parsons JT (2004) Src family kinases, key regulators of signal transduction. Oncogene 23(48):7906–7909
    • (2004) Oncogene , vol.23 , Issue.48 , pp. 7906-7909
    • Parsons, S.J.1    Parsons, J.T.2
  • 52
    • 65549114029 scopus 로고    scopus 로고
    • Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity
    • Frank CL, Tsai L-H (2009) Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity. Neuron 62(3):312–326
    • (2009) Neuron , vol.62 , Issue.3 , pp. 312-326
    • Frank, C.L.1    Tsai, L.-H.2
  • 53
    • 79958295957 scopus 로고    scopus 로고
    • Nitric oxide stimulates human neural progenitor cell migration via cGMPmediated signal transduction
    • Tegenge MA, Rockel TD, Fritsche E, Bicker G (2011) Nitric oxide stimulates human neural progenitor cell migration via cGMPmediated signal transduction. Cell Mol Life Sci 68(12):2089–2099
    • (2011) Cell Mol Life Sci , vol.68 , Issue.12 , pp. 2089-2099
    • Tegenge, M.A.1    Rockel, T.D.2    Fritsche, E.3    Bicker, G.4
  • 54
    • 84859476053 scopus 로고    scopus 로고
    • Rescue of neuronal migration deficits in a mouse model of fetal Minamata disease by increasing neuronal Ca2+ spike frequency
    • Fahrion JK, Komuro Y, Li Y, Ohno N, Littner Y, Raoult E, Galas L, Vaudry D, Komuro H (2012) Rescue of neuronal migration deficits in a mouse model of fetal Minamata disease by increasing neuronal Ca2+ spike frequency. Proc Natl Acad Sci 109(13):5057–5062
    • (2012) Proc Natl Acad Sci , vol.109 , Issue.13 , pp. 5057-5062
    • Fahrion, J.K.1    Komuro, Y.2    Li, Y.3    Ohno, N.4    Littner, Y.5    Raoult, E.6    Galas, L.7    Vaudry, D.8    Komuro, H.9
  • 55
    • 0000185397 scopus 로고
    • Fetal Minamata disease: A neuropathological study of two cases of intrauterine intoxication by a methyl mercury compound
    • Matsomoto H, Koya G, Takeuchi T (1965) Fetal Minamata disease: a neuropathological study of two cases of intrauterine intoxication by a methyl mercury compound. J Neuropathol Exp Neurol 24(4):563–574
    • (1965) J Neuropathol Exp Neurol , vol.24 , Issue.4 , pp. 563-574
    • Matsomoto, H.1    Koya, G.2    Takeuchi, T.3
  • 57
    • 0031443890 scopus 로고    scopus 로고
    • Review article: Pathology of Minamata disease
    • Eto K (1997) Review article: pathology of Minamata disease. Toxicol Pathol 25 (6):614–623
    • (1997) Toxicol Pathol , vol.25 , Issue.6 , pp. 614-623
    • Eto, K.1
  • 58
    • 0035684801 scopus 로고    scopus 로고
    • Toxic threats to neurologic development of children
    • Schettler T (2001) Toxic threats to neurologic development of children. Environ Health Perspect 109(Suppl 6):813–816
    • (2001) Environ Health Perspect , vol.109 , pp. 813-816
    • Schettler, T.1
  • 59
    • 0036177730 scopus 로고    scopus 로고
    • The three modern faces of mercury
    • Clarkson TW (2002) The three modern faces of mercury. Environ Health Perspect 110 (Suppl 1):11–23
    • (2002) Environ Health Perspect , vol.110 , pp. 11-23
    • Clarkson, T.W.1
  • 60
    • 0036938779 scopus 로고    scopus 로고
    • Neuronal migration disturbance and consequent cytoarchitecture in the cerebral cortex following transplacental administration of methylmercury
    • Kakita A, Inenaga C, Sakamoto M, Takahashi H (2002) Neuronal migration disturbance and consequent cytoarchitecture in the cerebral cortex following transplacental administration of methylmercury. Acta Neuropathol 104(4):409–417
    • (2002) Acta Neuropathol , vol.104 , Issue.4 , pp. 409-417
    • Kakita, A.1    Inenaga, C.2    Sakamoto, M.3    Takahashi, H.4
  • 61
    • 61849149397 scopus 로고    scopus 로고
    • Continuous exposure to low concentrations of methylmercury impairs cerebellar granule cell migration in organotypic slice culture
    • Mancini JD, Autio DM, Atchison WD (2009) Continuous exposure to low concentrations of methylmercury impairs cerebellar granule cell migration in organotypic slice culture. Neurotoxicology 30(2):203–208
    • (2009) Neurotoxicology , vol.30 , Issue.2 , pp. 203-208
    • Mancini, J.D.1    Autio, D.M.2    Atchison, W.D.3
  • 62
    • 0033911258 scopus 로고    scopus 로고
    • Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models
    • Rice D, Barone S Jr (2000) Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 108(Suppl 3):511–533
    • (2000) Environ Health Perspect , vol.108 , pp. 511-533
    • Rice, D.1    Barone, S.J.2
  • 64
    • 79961085142 scopus 로고    scopus 로고
    • Neurotoxicity of endocrine disruptors: Possible involvement in brain development and neurodegeneration
    • Masuo Y, Ishido M (2011) Neurotoxicity of endocrine disruptors: possible involvement in brain development and neurodegeneration. J Toxicol Environ Health B Crit Rev 14(5 7):346–369
    • (2011) J Toxicol Environ Health B Crit Rev , vol.14 , pp. 346-369
    • Masuo, Y.1    Ishido, M.2
  • 67
    • 0032965534 scopus 로고    scopus 로고
    • Central nervous system neuronal migration
    • Hatten ME (1999) Central nervous system neuronal migration. Annu Rev Neurosci 22 (1):511–539
    • (1999) Annu Rev Neurosci , vol.22 , Issue.1 , pp. 511-539
    • Hatten, M.E.1
  • 68
    • 77955936385 scopus 로고    scopus 로고
    • BDNF/ MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration
    • Ortega JA, Alcantara S (2010) BDNF/ MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration. Cereb Cortex 20 (9):2132–2144
    • (2010) Cereb Cortex , vol.20 , Issue.9 , pp. 2132-2144
    • Ortega, J.A.1    Alcantara, S.2
  • 69
    • 84881024631 scopus 로고    scopus 로고
    • Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
    • Semple BD, Blomgren K, Gimlin K, Ferriero DM, Noble-Haeusslein LJ (2013) Brain development in rodents and humans: identifying benchmarks of maturation and vulnerability to injury across species. Prog Neurobiol 106–107:1–16
    • (2013) Prog Neurobiol , vol.106 , pp. 1-16
    • Semple, B.D.1    Blomgren, K.2    Gimlin, K.3    Ferriero, D.M.4    Noble-Haeusslein, L.J.5
  • 70
    • 84876535935 scopus 로고    scopus 로고
    • Modeling transformations of neurodevelopmental sequences across mammalian species
    • Workman AD, Charvet CJ, Clancy B, Darlington RB, Finlay BL (2013) Modeling transformations of neurodevelopmental sequences across mammalian species. J Neurosci 33(17):7368–7383
    • (2013) J Neurosci , vol.33 , Issue.17 , pp. 7368-7383
    • Workman, A.D.1    Charvet, C.J.2    Clancy, B.3    Darlington, R.B.4    Finlay, B.L.5
  • 71
    • 0042164863 scopus 로고    scopus 로고
    • Developmental neurotoxicity of toluene: In vivo and in vitro effects on astroglial cells
    • Burry M, Guizzetti M, Oberdoerster J, Costa LG (2003) Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. Dev Neurosci 25(1):14–19
    • (2003) Dev Neurosci , vol.25 , Issue.1 , pp. 14-19
    • Burry, M.1    Guizzetti, M.2    Oberdoerster, J.3    Costa, L.G.4
  • 72
    • 0029827611 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein expression in rat brain and in radial glia culture is delayed by prenatal ethanol exposure
    • Valles S, Sancho‐Tello M, Minana R, Climent E, Renau‐Piqueras J, Guerri C (1996) Glial fibrillary acidic protein expression in rat brain and in radial glia culture is delayed by prenatal ethanol exposure. J Neurochem 67 (6):2425–2433
    • (1996) J Neurochem , vol.67 , Issue.6 , pp. 2425-2433
    • Valles, S.1    Sancho‐Tello, M.2    Minana, R.3    Climent, E.4    Renau‐Piqueras, J.5    Guerri, C.6
  • 73
    • 20544477599 scopus 로고    scopus 로고
    • Alcohol impairs astrogliogenesis by stem cells in rodent neurospheres
    • Vemuri MC, Chetty CS (2005) Alcohol impairs astrogliogenesis by stem cells in rodent neurospheres. Neurochem Int 47(12):129–135
    • (2005) Neurochem Int , vol.47 , Issue.12 , pp. 129-135
    • Vemuri, M.C.1    Chetty, C.S.2
  • 75
    • 0035066639 scopus 로고    scopus 로고
    • Biology of oligodendrocyte and myelin in the mammalian central nervous system
    • Baumann N, Pham-Dinh D (2001) Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev 81 (2):871–927
    • (2001) Physiol Rev , vol.81 , Issue.2 , pp. 871-927
    • Baumann, N.1    Pham-Dinh, D.2
  • 76
    • 0030273439 scopus 로고    scopus 로고
    • Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
    • Gross RE, Mehler MF, Mabie PC, Zang Z, Santschi L, Kessler JA (1996) Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron 17 (4):595–606
    • (1996) Neuron , vol.17 , Issue.4 , pp. 595-606
    • Gross, R.E.1    Mehler, M.F.2    Mabie, P.C.3    Zang, Z.4    Santschi, L.5    Kessler, J.A.6
  • 77
    • 0030916680 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial–astroglial progenitor cells
    • Mabie P, Mehler M, Marmur R, Papavasiliou A, Song Q, Kessler J (1997) Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial–astroglial progenitor cells. J Neurosci 17(11):4112–4120
    • (1997) J Neurosci , vol.17 , Issue.11 , pp. 4112-4120
    • Mabie, P.1    Mehler, M.2    Marmur, R.3    Papavasiliou, A.4    Song, Q.5    Kessler, J.6
  • 78
    • 84862138497 scopus 로고    scopus 로고
    • The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation
    • Bond AM, Bhalala OG, Kessler JA (2012) The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation. Dev Neurobiol 72(7):1068–1084
    • (2012) Dev Neurobiol , vol.72 , Issue.7 , pp. 1068-1084
    • Bond, A.M.1    Bhalala, O.G.2    Kessler, J.A.3
  • 79
    • 84902532010 scopus 로고    scopus 로고
    • Temporal oligodendrocyte lineage progression: In vitro models of proliferation, differentiation and myelination
    • Barateiro A, Fernandes A (2014) Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination. Biochim Biophys Acta 1843 (9):1917–1929
    • (2014) Biochim Biophys Acta , vol.1843 , Issue.9 , pp. 1917-1929
    • Barateiro, A.1    Fernandes, A.2
  • 80
    • 0342437522 scopus 로고    scopus 로고
    • Hypothyroidism coordinately and transiently affects myelin protein gene expression in most rat brain regions during postnatal development
    • Ibarrola N, Rodríguez-Peña A (1997) Hypothyroidism coordinately and transiently affects myelin protein gene expression in most rat brain regions during postnatal development. Brain Res 752(1):285–293
    • (1997) Brain Res , vol.752 , Issue.1 , pp. 285-293
    • Ibarrola, N.1    Rodríguez-Peña, A.2
  • 81
    • 0032528158 scopus 로고    scopus 로고
    • Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system
    • Marta CB, Adamo AM, Soto EF, Pasquini JM (1998) Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J Neurosci Res 53 (2):251–259
    • (1998) J Neurosci Res , vol.53 , Issue.2 , pp. 251-259
    • Marta, C.B.1    Adamo, A.M.2    Soto, E.F.3    Pasquini, J.M.4
  • 82
    • 0027531737 scopus 로고
    • Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain
    • Rodriguez-Pena A, Ibarrola N, Iñiguez MA, Munoz A, Bernal J (1993) Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain. J Clin Investig 91(3):812–818
    • (1993) J Clin Investig , vol.91 , Issue.3 , pp. 812-818
    • Rodriguez-Pena, A.1    Ibarrola, N.2    Iñiguez, M.A.3    Munoz, A.4    Bernal, J.5
  • 83
    • 81155134840 scopus 로고    scopus 로고
    • Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ‐opioid‐and nociceptin/orphanin FQ receptors in cell development: Implications for drug addiction treatment during pregnancy
    • Eschenroeder AC, Vestal‐Laborde AA, Sanchez ES, Robinson SE, Sato‐Bigbee C (2012) Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ‐opioid‐and nociceptin/orphanin FQ receptors in cell development: implications for drug addiction treatment during pregnancy. Glia 60(1):125–136
    • (2012) Glia , vol.60 , Issue.1 , pp. 125-136
    • Eschenroeder, A.C.1    Vestal‐Laborde, A.A.2    Sanchez, E.S.3    Robinson, S.E.4    Sato‐Bigbee, C.5
  • 84
    • 51349159322 scopus 로고    scopus 로고
    • Opioid addiction and pregnancy: Perinatal exposure to buprenorphine affects myelination in the developing brain
    • Sanchez ES, Bigbee JW, Fobbs W, Robinson SE, Sato‐Bigbee C (2008) Opioid addiction and pregnancy: perinatal exposure to buprenorphine affects myelination in the developing brain. Glia 56(9):1017–1027
    • (2008) Glia , vol.56 , Issue.9 , pp. 1017-1027
    • Sanchez, E.S.1    Bigbee, J.W.2    Fobbs, W.3    Robinson, S.E.4    Sato‐Bigbee, C.5
  • 85
    • 79951953171 scopus 로고    scopus 로고
    • The mechanism of vanadium-mediated developmental hypomyelination is related to destruction of oligodendrocyte progenitors through a relationship with ferritin and iron
    • Todorich B, Olopade JO, Surguladze N, Zhang X, Neely E, Connor JR (2011) The mechanism of vanadium-mediated developmental hypomyelination is related to destruction of oligodendrocyte progenitors through a relationship with ferritin and iron. Neurotox Res 19(3):361–373
    • (2011) Neurotox Res , vol.19 , Issue.3 , pp. 361-373
    • Todorich, B.1    Olopade, J.O.2    Surguladze, N.3    Zhang, X.4    Neely, E.5    Connor, J.R.6
  • 86
    • 77952744918 scopus 로고    scopus 로고
    • Curcumin protects preoligodendrocytes from activated microglia in vitro and in vivo
    • He L-f, H-j C, L-h Q, G-y C, Buzby JS (2010) Curcumin protects preoligodendrocytes from activated microglia in vitro and in vivo. Brain Res 1339:60–69
    • (2010) Brain Res , vol.1339 , pp. 60-69
    • He, L.-F.1    H-J, C.2    L-H, Q.3    G-Y, C.4    Buzby, J.S.5
  • 87
    • 0037335027 scopus 로고    scopus 로고
    • Oligodendroglia in developmental neurotoxicity
    • Deng W, Poretz RD (2003) Oligodendroglia in developmental neurotoxicity. Neurotoxicology 24(2):161–178
    • (2003) Neurotoxicology , vol.24 , Issue.2 , pp. 161-178
    • Deng, W.1    Poretz, R.D.2
  • 89
    • 0017070315 scopus 로고
    • Biochemical differentiation of mechanically dissociated mammalian brain in aggregating cell culture
    • Honegger P, Richelson E (1976) Biochemical differentiation of mechanically dissociated mammalian brain in aggregating cell culture. Brain Res 109(2):335–354
    • (1976) Brain Res , vol.109 , Issue.2 , pp. 335-354
    • Honegger, P.1    Richelson, E.2
  • 90
    • 0030602015 scopus 로고    scopus 로고
    • Comparison of the developmental effects of two mercury compounds on glial cells and neurons in aggregate cultures of rat telencephalon
    • Monnet-Tschudi F, Zurich M-G, Honegger P (1996) Comparison of the developmental effects of two mercury compounds on glial cells and neurons in aggregate cultures of rat telencephalon. Brain Res 741(1):52–59
    • (1996) Brain Res , vol.741 , Issue.1 , pp. 52-59
    • Monnet-Tschudi, F.1    Zurich, M.-G.2    Honegger, P.3
  • 98
    • 0347003695 scopus 로고    scopus 로고
    • Efficient gene transfer into the human natural killer cell line, NKL, using the Amaxa nucleofection system™
    • Maasho K, Marusina A, Reynolds NM, Coligan JE, Borrego F (2004) Efficient gene transfer into the human natural killer cell line, NKL, using the Amaxa nucleofection system™. J Immunol Methods 284(1):133–140
    • (2004) J Immunol Methods , vol.284 , Issue.1 , pp. 133-140
    • Maasho, K.1    Marusina, A.2    Reynolds, N.M.3    Coligan, J.E.4    Borrego, F.5
  • 99
    • 85127646772 scopus 로고    scopus 로고
    • Viral vectors in neurobiology: Therapeutic and research applications. Molecular virology
    • Coura R (2012) Viral vectors in neurobiology: therapeutic and research applications. Molecular virology, Chapter 5. pp 75–92
    • (2012) Chapter , vol.5 , pp. 75-92
    • Coura, R.1
  • 100
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia G, Singer O, Verma IM (2006) Production and purification of lentiviral vectors. Nat Protoc 1(1):241–245
    • (2006) Nat Protoc , vol.1 , Issue.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 101
    • 0030272971 scopus 로고    scopus 로고
    • Viral vectors for modulating gene expression in neurons
    • Slack RS, Miller FD (1996) Viral vectors for modulating gene expression in neurons. Curr Opin Neurobiol 6(5):576–583
    • (1996) Curr Opin Neurobiol , vol.6 , Issue.5 , pp. 576-583
    • Slack, R.S.1    Miller, F.D.2
  • 102
  • 104
    • 84872731930 scopus 로고    scopus 로고
    • Aging-induced Nrf2ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation
    • L’Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Impagnatiello F, Pluchino S, Marchetti B (2013) Aging-induced Nrf2ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation. J Neurosci 33(4):1462–1485
    • (2013) J Neurosci , vol.33 , Issue.4 , pp. 1462-1485
    • L’Episcopo, F.1    Tirolo, C.2    Testa, N.3    Caniglia, S.4    Morale, M.C.5    Impagnatiello, F.6    Pluchino, S.7    Marchetti, B.8
  • 107
    • 84887098518 scopus 로고    scopus 로고
    • Organ‐on‐a‐chip technology and microfluidic whole‐body models for pharmacokinetic drug toxicity screening
    • Lee JB, Sung JH (2013) Organ‐on‐a‐chip technology and microfluidic whole‐body models for pharmacokinetic drug toxicity screening. Biotechnol J 8 (11):1258–1266
    • (2013) Biotechnol J , vol.8 , Issue.11 , pp. 1258-1266
    • Lee, J.B.1    Sung, J.H.2
  • 109
    • 69949186235 scopus 로고    scopus 로고
    • Determinants of regional and local diversity within the astroglial lineage of the normal central nervous system
    • Hewett JA (2009) Determinants of regional and local diversity within the astroglial lineage of the normal central nervous system. J Neurochem 110(6):1717–1736
    • (2009) J Neurochem , vol.110 , Issue.6 , pp. 1717-1736
    • Hewett, J.A.1
  • 110
    • 34447093523 scopus 로고    scopus 로고
    • An in vitro approach to assess the toxicity of certain food contaminants: Methylmercury and polychlorinated biphenyls
    • Costa LG, Fattori V, Giordano G, Vitalone A (2007) An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls. Toxicology 237(1):65–76
    • (2007) Toxicology , vol.237 , Issue.1 , pp. 65-76
    • Costa, L.G.1    Fattori, V.2    Giordano, G.3    Vitalone, A.4


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