Increased interstitial white matter neuron density in the dorsolateral prefrontal cortex of people with schizophrenia

Biological Psychiatry

Volumn 69, Issue 1, 2011, Pages 63-70

  Yang, Yang ^a,b   Fung, Samantha J ^a   Rothwell, Alice ^a   Tianmei, Si ^b   Weickert, Cynthia Shannon ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b PEKING UNIVERSITY SIXTH HOSPITAL   (China)

Author keywords

Interneuron; Interstitial white matter neuron; NeuN; Neuropeptide Y; Schizophrenia; Somatostatin

Indexed keywords

CELL NUCLEUS ANTIGEN; MESSENGER RNA; NEUROPEPTIDE Y; SOMATOSTATIN;

ADULT; AGED; ARTICLE; CELL DENSITY; CELL SUBPOPULATION; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE DURATION; FEMALE; GENE EXPRESSION; GRAY MATTER; HEMISPHERE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERNEURON; INTERSTITIAL WHITE MATTER NEURON; MALE; MARKER GENE; NERVE CELL; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHIZOPHRENIA; WHITE MATTER;

ANTIGENS, NUCLEAR; CEREBRUM; FEMALE; HUMANS; HYPERPLASIA; INTERNEURONS; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; NERVE TISSUE PROTEINS; NEUROPEPTIDE Y; PREFRONTAL CORTEX; SCHIZOPHRENIA; SOMATOSTATIN;

EID: 78650033884     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.08.020     Document Type: Article

References (55)

1. P.J. Harrison Schizophrenia: A disorder of neurodevelopment? Curr Opin Neurobiol 7 1997 285 289
2. D.A. Lewis, and P. Levitt Schizophrenia as a disorder of neurodevelopment Annu Rev Neurosci 25 2002 409 432
3. C.S. Weickert, and D.R. Weinberger A candidate molecule approach to defining developmental pathology in schizophrenia Schizophr Bull 24 1998 303 316
4. C.S. Weickert, and J.E. Kleinman The neuroanatomy and neurochemistry of schizophrenia Psychiatr Clin North Am 21 1998 57 75
5. D.A. Lewis, J.N. Pierri, D.W. Volk, D.S. Melchitzky, and T.U. Woo Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia Biol Psychiatry 46 1999 616 626
6. D.A. Lewis, and G. Gonzalez-Burgos Neuroplasticity of neocortical circuits in schizophrenia Neuropsychopharmacology 33 2008 141 165
7. T. Hashimoto, D.W. Volk, S.M. Eggan, K. Mirnics, J.N. Pierri, Z. Sun, and A.R. Sampson Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia J Neurosci 23 2003 6315 6326
8. T. Hashimoto, H.H. Bazmi, K. Mirnics, Q. Wu, A.R. Sampson, and D.A. Lewis Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia Am J Psychiatry 165 2008 479 489
9. T. Hashimoto, D. Arion, T. Unger, J.G. Maldonado-Aviles, H.M. Morris, D.W. Volk, and K. Mirnics Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia Mol Psychiatry 13 2008 147 161
10. S. Akbarian, J.J. Kim, S.G. Potkin, J.O. Hagman, A. Tafazzoli, W.E. Bunney Jr, and E.G. Jones Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics Arch Gen Psychiatry 52 1995 258 266
11. C.E. Duncan, M.J. Webster, D.A. Rothmond, S. Bahn, M. Elashoff, and C. Shannon Weickert Prefrontal GABA(A) receptor alpha-subunit expression in normal postnatal human development and schizophrenia J Psychiatr Res 44 2010 673 681
12. A. Guidotti, J. Auta, J.M. Davis, V. Di-Giorgi-Gerevini, Y. Dwivedi, D.R. Grayson, and F. Impagnatiello Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: A postmortem brain study Arch Gen Psychiatry 57 2000 1061 1069
13. M. Thompson, C.S. Weickert, E. Wyatt, and M.J. Webster Decreased glutamic acid decarboxylase(67) mRNA expression in multiple brain areas of patients with schizophrenia and mood disorders J Psychiatr Res 43 2009 970 977
14. H.M. Morris, T. Hashimoto, and D.A. Lewis Alterations in somatostatin mRNA expression in the dorsolateral prefrontal cortex of subjects with schizophrenia or schizoaffective disorder Cereb Cortex 18 2008 1575 1587
15. Fung S, Webster M, Sivagnanasundaram S, Duncan C, Elashoff M, Shannon Weickert C (in press): Expression of interneuron markers in the dorsolateral prefrontal cortex of the developing human and in schizophrenia. Am J Psychiatry.
16. F.M. Benes, J. McSparren, E.D. Bird, J.P. SanGiovanni, and S.L. Vincent Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients Arch Gen Psychiatry 48 1991 996 1001
17. G.P. Reynolds, and C.L. Beasley GABAergic neuronal subtypes in the human frontal cortexdevelopment and deficits in schizophrenia J Chem Neuroanat 22 2001 95 100
18. C.L. Beasley, Z.J. Zhang, I. Patten, and G.P. Reynolds Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins Biol Psychiatry 52 2002 708 715
19. I. Kostovic, and P. Rakic Cytology and time of origin of interstitial neurons in the white matter in infant and adult human and monkey telencephalon J Neurocytol 9 1980 219 242
20. G. Meyer, P. Wahle, A. Castaneyra-Perdomo, and R. Ferres-Torres Morphology of neurons in the white matter of the adult human neocortex Exp Brain Res 88 1992 204 212
21. R.L. Reep Cortical layer VII and persistent subplate cells in mammalian brains Brain Behav Evol 56 2000 212 234
22. J.J. Chun, and C.J. Shatz Interstitial cells of the adult neocortical white matter are the remnant of the early generated subplate neuron population J Comp Neurol 282 1989 555 569
23. S.J. Butt, M. Fuccillo, S. Nery, S. Noctor, A. Kriegstein, J.G. Corbin, and G. Fishell The temporal and spatial origins of cortical interneurons predict their physiological subtype Neuron 48 2005 591 604
24. M. Fogarty, M. Grist, D. Gelman, O. Marin, V. Pachnis, and N. Kessaris Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex J Neurosci 27 2007 10935 10946
25. Q. Xu, M. Tam, and S.A. Anderson Fate mapping Nkx2.1-lineage cells in the mouse telencephalon J Comp Neurol 506 2008 16 29
26. S. Akbarian, W.E. Bunney Jr, S.G. Potkin, S.B. Wigal, J.O. Hagman, C.A. Sandman, and E.G. Jones Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development Arch Gen Psychiatry 50 1993 169 177 (Pubitemid 23077471)
27. S.A. Anderson, D.W. Volk, and D.A. Lewis Increased density of microtubule associated protein 2-immunoreactive neurons in the prefrontal white matter of schizophrenic subjects Schizophr Res 19 1996 111 119
28. S.L. Eastwood, and P.J. Harrison Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: Towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis Mol Psychiatry 8 2003 821-731
29. S.L. Eastwood, and P.J. Harrison Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia Schizophr Res 79 2005 181 188
30. B. Kirkpatrick, N.C. Messias, R.R. Conley, and R.C. Roberts Interstitial cells of the white matter in the dorsolateral prefrontal cortex in deficit and nondeficit schizophrenia J Nerv Ment Dis 191 2003 563 567
31. C.L. Beasley, D.R. Cotter, and I.P. Everall Density and distribution of white matter neurons in schizophrenia, bipolar disorder and major depressive disorder: No evidence for abnormalities of neuronal migration Mol Psychiatry 7 2002 564 570
32. R.J. Mullen, C.R. Buck, and A.M. Smith NeuN, a neuronal specific nuclear protein in vertebrates Development 116 1992 201 211
33. H.B. Sarnat, D. Nochlin, and D.E. Born Neuronal nuclear antigen (NeuN): A marker of neuronal maturation in early human fetal nervous system Brain Dev 20 1998 88 94
34. L. Dehmelt, and S. Halpain The MAP2/Tau family of microtubule-associated proteins Genome Biol 6 2005 204
35. C.S. Weickert, D. Sheedy, D.A. Rothmond, I. Dedova, S. Fung, T. Garrick, and J. Wong Selection of reference gene expression in a schizophrenia brain cohort Aust N Z J Psychiatry 44 2010 59 70
36. G. Rajkowska, and P.S. Goldman-Rakic Cytoarchitectonic definition of prefrontal areas in the normal human cortex I. Remapping of areas 9 and 46 using quantitative criteria Cereb Cortex 5 1995 307 322
37. H.J. Whitfield Jr, L.S. Brady, M.A. Smith, E. Mamalaki, R.J. Fox, and M. Herkenham Optimization of cRNA probe in situ hybridization methodology for localization of glucocorticoid receptor mRNA in rat brain: a detailed protocol Cell Mol Neurobiol 10 1990 145 157
38. S. Rasband Image sJ 1997-2009 U.S. National Institutes of Health Bethesda http://rsb.info.nih.gov/ij
39. C.M. Connor, Y. Guo, and S. Akbarian Cingulate white matter neurons in schizophrenia and bipolar disorder Biol Psychiatry 66 2009 486 493
40. B. Kirkpatrick, R.C. Conley, A. Kakoyannis, R.L. Reep, and R.C. Roberts Interstitial cells of the white matter in the inferior parietal cortex in schizophrenia: An unbiased cell-counting study Synapse 34 1999 95 102
41. H.M. Morris, R.E. Stopczynski, and D.A. Lewis NPY mRNA expression in the prefrontal cortex: Selective reduction in the superficial white matter of subjects with schizoaffective disorder Schizophr Res 115 2009 261 269
42. S. Akbarian, J.J. Kim, S.G. Potkin, W.P. Hetrick, W.E. Bunney Jr, and E.G. Jones Maldistribution of interstitial neurons in prefrontal white matter of the brains of schizophrenic patients Arch Gen Psychiatry 53 1996 425 436
43. C.L. Beasley, M. Honavar, I.P. Everall, and D. Cotter Two-dimensional assessment of cytoarchitecture in the superior temporal white matter in schizophrenia, major depressive disorder and bipolar disorder Schizophr Res 115 2009 156 162
44. F.M. Benes, and N. Lange Two-dimensional versus three-dimensional cell counting: A practical perspective Trends Neurosci 24 2001 11 17
45. D.J. Price, S. Aslam, L. Tasker, and K. Gillies Fates of the earliest generated cells in the developing murine neocortex J Comp Neurol 377 1997 414 422
46. D.W. Meechan, E.S. Tucker, T.M. Maynard, and A.-S. LaMantia Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome Proc Natl Acad Sci U S A 106 2009 16434 16445
47. K. Hashimoto-Torii, M. Torii, M.R. Sarkisian, C.M. Bartley, J. Shen, F. Radtke, and T. Gridley Interaction between reelin and notch signaling regulates neuronal migration in the cerebral cortex Neuron 60 2008 273 284
48. D.R. Kornack, and P. Rakic Cell proliferation without neurogenesis in adult primate neocortex Science 294 2001 2127 2130
49. E. Gould, A.J. Reeves, M.S. Graziano, and C.G. Gross Neurogenesis in the neocortex of adult primates Science 286 1999 548 552
50. Y. Cai, K. Xiong, Y. Chu, D.W. Luo, X.G. Luo, X.Y. Yuan, and R.G. Struble Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups Exp Neurol 216 2009 342 356
51. R.R. Dawirs, K. Hildebrandt, and G. Teuchert-Noodt Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus J Neural Transm 105 1998 317 327
52. N.D. Halim, C.S. Weickert, B.W. McClintock, D.R. Weinberger, and B.K. Lipska Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus Neuropsychopharmacology 29 2004 1063 1069
53. H.D. Wang, F.D. Dunnavant, T. Jarman, and A.Y. Deutch Effects of antipsychotic drugs on neurogenesis in the forebrain of the adult rat Neuropsychopharmacology 29 2004 1230 1238
54. J. Hunsberger, D.R. Austin, I.D. Henter, and G. Chen The neurotrophic and neuroprotective effects of psychotropic agents Dialogues Clin Neurosci 11 2009 333 348
55. T.J. Cullen, M.A. Walker, S.L. Eastwood, M.M. Esiri, P.J. Harrison, and T.J. Crow Anomalies of asymmetry of pyramidal cell density and structure in dorsolateral prefrontal cortex in schizophrenia Br J Psychiatry 188 2006 26 31