Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E

NeuroToxicology

Volumn 27, Issue 6, 2006, Pages 970-981

  Burke, Kelly ^a   Cheng, Yinghong ^a   Li, Baogang ^a   Petrov, Alex ^a   Joshi, Pushkar ^a   Berman, Robert F ^b   Reuhl, Kenneth R ^c   DiCicco Bloom, Emanuel ^a,d  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

Cell cycle; Cell survival; Cerebellar granule precursors; Cerebral cortex; Cyclin E; Hippocampus; Mercury; Neural stem cell; Neurogenesis; Proliferation

Indexed keywords

CASPASE 3; CYCLIN DEPENDENT KINASE 2; CYCLIN E; METHYLMERCURY; PROTEIN P27; PROTEIN P57;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA SYNTHESIS; DRUG INHIBITION; EMBRYO; ENVIRONMENTAL EXPOSURE; FEMALE; GRANULE CELL; IN VITRO STUDY; IN VIVO STUDY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; POLLUTION; PRIORITY JOURNAL; RAT; STEM CELL;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BRAIN; BROMODEOXYURIDINE; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN E; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; METHYLMERCURY COMPOUNDS; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; THYMIDINE; TIME FACTORS; TRITIUM;

EID: 33751508327     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2006.09.001     Document Type: Article

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