Developments in understanding and applying prebiotics in research and practice—an ISAPP conference paper

Journal of Applied Microbiology

Volumn 128, Issue 4, 2020, Pages 934-949

  Scott, K P ^a   Grimaldi, R ^b   Cunningham, M ^c   Sarbini, S R ^d   Wijeyesekera, A ^b   Tang, M L K ^e   Lee, J C Y ^f   Yau, Y F ^f   Ansell, J ^g   Theis, S ^h   Yang, K ⁱ   Menon, R ^j   Arfsten, J ^k   Manurung, S ^l   Gourineni, V ^m   Gibson, G R ^b  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

^c Metagenics   (Australia)

^d DEPARTMENT OF CROP SCIENCE   (Malaysia)

^e ROYAL CHILDREN'S HOSPITAL   (Australia)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

^g Zespri International Limited   (New Zealand)

^h BENEO   (Germany)

ⁱ WESTERN UNIVERSITY   (Canada)

^j GENERAL MILLS INC   (United States)

^k Nestlé Product and Technology Center Dairy   (Switzerland)

^l RECKITT BENCKISER   (United Kingdom)

^m Global Nutrition Ingredion Inc   (United States)

more..

Author keywords

gut fermentation; health benefits; ISAPP; microbiome; prebiotics

Indexed keywords

HEALTH RISKS; SALES;

CONFERENCE PAPERS; DIETARY COMPONENTS; GUT FERMENTATION; GUT MICROBIOTA; HEALTH BENEFITS; ISAPP; MICROBIOME; PREBIOTICS; PROBIOTICS; SINGAPORE;

PROBIOTICS;

CARBOHYDRATE; POLYPHENOL; PREBIOTIC AGENT; PROBIOTIC AGENT; SHORT CHAIN FATTY ACID;

BIOTIC FACTOR; COMMERCIALIZATION; FERMENTATION; FOOD INDUSTRY; HUMAN ACTIVITY; MARKET;

ASIAN; CHEMICAL COMPOSITION; CLINICAL PRACTICE; CLINICAL RESEARCH; ECONOMIC ASPECT; FUNCTIONAL FOOD; HEALTH CARE POLICY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLORA; METABOLIC FINGERPRINTING; METHODOLOGY; MICROBIOME; PLANT; REVIEW; SCIENTIFIC LITERATURE; THERAPY EFFECT; ANIMAL; DIET; FOOD INDUSTRY; HEALTH CARE ORGANIZATION; LEGISLATION AND JURISPRUDENCE; MEDICAL RESEARCH; ORGANIZATION; SINGAPORE;

SINGAPORE [SOUTHEAST ASIA];

ANIMALIA;

ANIMALS; BIOMEDICAL RESEARCH; CONGRESSES AS TOPIC; DIET; FOOD INDUSTRY; GASTROINTESTINAL MICROBIOME; HUMANS; PREBIOTICS; SINGAPORE; SOCIETIES, SCIENTIFIC;

EID: 85073807312     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.14424     Document Type: Review

References (69)

1. Arshad, N.S., Zaman, S.A., Rawi, M.H. and Sarbini, S.R. (2018) Resistant starch evaluation and in vitro fermentation of lemantak (native sago starch), for prebiotic assessment. Int Food Res J 25, 951–957.
2. Bajury, D.M.A., Rawi, M.H., Sazali, I.H., Abdullah, A. and Sarbini, S.R. (2017) Prebiotic evaluation of red seaweed (Kappaphycus alvarezii) using in vitro colon model. Int J Food Sci Nutr 68, 821–828.
3. Belenguer, A., Duncan, S.H., Calder, A.G., Holtrop, G., Louis, P., Lobley, G.E. and Flint, H.J. (2006) Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut. Appl Environ Microbiol 72, 3593–3599.
4. den Besten, G., van Eunen, K., Groen, A.K., Venema, K., Reijngoud, D.J. and Bakker, B.M. (2013) The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res 54, 2325–2340.
5. Blatchford, P., Stoklosinski, H., Walton, G., Swann, J., Gibson, G., Gearry, R. and Ansell, J. (2015) Kiwifruit fermentation drives positive gut microbial and metabolic changes irrespective of initial microbiota composition. Bioactive Carb Dietary Fibre 6, 37–45.
6. Cardona, F., Andrés-Lacueva, C., Tulipani, S., Tinahones, F.J. and Queipo-Ortuño, M.I. (2013) Benefits of polyphenols on gut microbiota and implications in human health. J Nutr Biochem 24, 1415–1422.
7. Carnachan, S., Bootten, T., Mishra, S., Monro, J. and Sims, I. (2012) Effects of simulated digestion in vitro on cell wall polysaccharides from kiwifruit (Actinidia spp.). Food Chem 133, 132–139.
8. Chambers, E.S., Morrison, D.J. and Frost, G. (2015) Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms? Proc Nutr Soc 74, 328–336.
9. Charalampopoulos, D., Wang, R., Pandiella, S.S. and Webb, C. (2002) Application of cereals and cereal components in functional foods: a review. Int J Food Microbiol 79, 131–141.
10. Costabile, A., Walton, G.E., Tzortzis, G., Vulevic, J., Charalampopoulos, D. and Gibson, G.R. (2015a) Development of a bread delivery vehicle for dietary prebiotics to enhance food functionality targeted at those with metabolic syndrome. Gut Microbes 6, 300–309.
11. Costabile, A., Walton, G.E., Tzortzis, G., Vulevic, J., Charalampopoulos, D. and Gibson, G.R. (2015b) Effects of orange juice formulation on prebiotic functionality using an in vitro colonic model system. PLoS ONE 10, e0121955.
12. Cremon, C., Ansell, J., Pagano, I., Kuhn-Sherlock, B., Drummond, L., Barbaro, M., Capelli, E., Belacosa, L. et al. (2018) A randomised, controlled single-blind, cross-over study assessing the effect of green kiwifruit on digestive functions and microbiota in constipated patients. Gastroenterol 154(Suppl 1), S565–566.
13. Cummings, J.H., Rombeau, J.L. and Sakata, T. (eds.) (1995) Physiological and Clinical Aspects of Short-Chain Fatty Acids. Cambridge NY: Cambridge University Press.
14. Davis, L.M.G., Martínez, I., Walter, J. and Hutkins, R. (2010) A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol 144, 285–292.
15. De Smet, I., De Boever, P. and Verstraete, W. (1998) Cholesterol lowering in pigs through enhanced bacterial bile salt hydrolase activity. Brit J Nutr 79, 185–194.
16. De Vuyst, L. and Leroy, F. (2011) Cross-feeding between bifidobacteria and butyrate-producing colon bacteria explains bifdobacterial competitiveness, butyrate production, and gas production. Int J Food Microbiol 149, 73–80.
17. Deelchand, D.K., Shestov, A.A., Koski, D.M., Ugurbil, K. and Henry, P.G. (2009) Acetate transport and utilization in the rat brain. J Neurochem 109(S1), 46–54.
18. Dienel, G.A., Popp, D., Drew, P.D., Ball, K., Krisht, A. and Cruz, N.F. (2001) Preferential labeling of glial and meningial brain tumors with [2-(14)C]acetate. J Nucl Med 42, 1243–1250.
19. Duncan, S.H., Russell, W.R., Quartieri, A., Rossi, M., Parkhill, J., Walker, A.W. and Flint, H.J. (2016) Wheat bran promotes enrichment within the human colonic microbiota of butyrate-producing bacteria that release ferulic acid. Env Microbiol 18, 2214–2225.
20. Edmands, W.M., Beckonert, O.P., Stella, C., Campbell, A., Lake, B.G., Lindon, J.C., Holmes, E. and Gooderham, N.J. (2011) Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling. J Proteome Res 10, 4513–4521.
21. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) (2015) Scientific opinion on the substantiation of a health claim related to “native chicory inulin” and maintenance of normal defecation by increasing stool frequency pursuant to Article 13.5 of Regulation (EC) No 1924/2006. EFSA. https://www.efsa.europa.eu/en/efsajournal/pub/3951.
22. El Khoury, D., Cuda, C., Luhovyy, B.L. and Anderson, G.H. (2012) Βeta glucan: health benefits in obesity and metabolic syndrome. J Nutr Metab 28, 1–28.
23. Ge, H., Li, X., Weiszmann, J., Wang, P., Baribault, H., Chen, J.L., Tian, H. and Li, Y. (2008) Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149, 4519–4526.
24. Gibson, G.R. and Roberfroid, M.B. (1995) Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 125, 1401–1412.
25. Gibson, G.R., Probert, H.M., van Loo, J.A.E., Rastall, R.A. and Roberfroid, M.B. (2004) Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 17, 259–275.
26. Gibson, G.R., Hutkins, R., Sanders, M.E., Prescott, S.L., Reimer, R.A., Salminen, S.J., Scott, K., Stanton, C. et al. (2017) Expert consensus document: the International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol 14, 491–502.
27. Granato, D., Branco, G.F., Nazzaro, F., Cruz, A.G. and Faria, J.A. (2010) Functional foods and nondairy probiotic food development: trends, concepts, and products. Comp Rev Food Sci Food Safety 9, 292–302.
28. Han, K.S., Balan, P., Molist Gasa, F. and Boland, M. (2011) Green kiwifruit modulates the colonic microbiota in growing pigs. Lett Appl Microbiol 52, 379–385.
29. Hornung, B., Martins Dos Santos, V.A.P., Smidt, H. and Schaap, P.J. (2018) Studying microbial functionality within the gut ecosystem by systems biology. Genes Nutr 13, 1–19.
30. Huynh, B.L., Palmer, L., Mather, D.E., Wallwork, H., Graham, R.D., Welch, R.M. and Stangoulis, J.C.R. (2008) Genotypic variation in wheat grain fructan content revealed by a simplified HPLC method. J Cereal Sci 48, 369–378.
31. Illman, R.J., Topping, D.L., McIntosh, G.H., Trimble, R.P., Storer, G.B., Taylor, M.N. and Cheng, B.Q. (1988) Hypocholesterolaemic effects of dietary propionate: studies in whole animals and perfused rat liver. Ann Nutr Metab 32, 97–107.
32. Imamura, L., Hisamitsu, K. and Kobashi, K. (1994) Purification and characterization of β-fructofuranosidase from Bifidobacterium infantis. Biol Pharm Bull 17, 596–602.
33. Johnson, C.R., Thavarajah, D., Combs, G.F. Jr and Thavarajah, P. (2013) Lentil (Lens culinaris L.): A prebiotic-rich whole food legume. Food Res Int 51, 107–113.
34. Joshi, D., Somdatta, R. and Sugato, B. (2018) Prebiotics: a functional food in health and disease. In Natural Products and Drug Discovery, an Integrated Approach eds. Mandal, S.C., Mandal, V. and Konishi, T., pp 507–523. Amsterdam: Elsevier.
35. Kang, J., Price, W.E., Ashton, J., Tapsell, L.C. and Johnson, S. (2016) Identification and characterization of phenolic compounds in hydromethanolic extracts of sorghum wholegrains by LC-ESI-MS(n). Food Chem 211, 215–226.
36. Kemperman, R.A., Gross, G., Mondot, S., Possemiers, S., Marzorati, M., Van de Wiele, T., Doré, J. and Vaughan, E.E. (2013) Impact of polyphenols from black tea and red wine/grape juice on a gut model microbiome. Food Res Int 53, 659–669.
37. Kotilainen, L., Rajalahti, R., Ragasa, C. and Pehu, E. (2006) Health Enhancing Foods: Opportunities for Strengthening Developing Countries. Agriculture and Rural Development discussion paper; no. 30. Washington, DC: World Bank. http://documents.worldbank.org/curated/en/314421468324275640/Health-enhancing-foods-opportunities-for-strengthening-developing-countries.
38. Kumar, A.K., Makkar, V., De Boeck, H.P. and Becker, K. (2011) Non-starch polysaccharides and their role in fish nutrition – A review. Food Chem 127, 1409–1426.
39. Li, F., Hullar, M.A., Schwarz, Y. and Lampe, J.W. (2009) Human gut bacterial communities are altered by addition of cruciferous vegetables to a controlled fruit- and vegetable-free diet. J Nutr 139, 1685–1691.
40. Liu, Z., Lin, X., Huang, G., Zhang, W., Rao, P. and Ni, L. (2014) Prebiotic effects of almonds and almond skins on intestinal microbiota in healthy adult humans. Anaerobe 26, 1–6.
41. van Loo, J., Coussement, P., de Leenheer, L., Hoebregs, H. and Smits, G. (1995) On the presence of inulin and oligofructose as natural ingredients in the western diet. Crit Rev Food Sci Nutr 35, 525–552.
42. Louis, P., Young, P., Holtrop, G. and Flint, H.J. (2010) Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene. Env Microbiol 12, 304–314.
43. Lu, Q., Summanen, P.H., Lee, R., Huang, J., Henning, S.M., Heber, D., Finegold, S.M. and Li, Z. (2017) Prebiotic potential and chemical composition of seven culinary spice extracts. J Food Sci 82, 1807–1813.
44. Luong, A., Hannah, V.C., Brown, M.S. and Goldstein, J.L. (2000) Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins. J Biol Chem 275, 26458–26466.
45. Marotti, I., Bregola, V., Aloisio, I., Di Gioia, D., Bosi, S., Silvestro, R.D., Quinn, R. and Dinelli, G. (2012) Prebiotic effect of soluble fibres from modern and old durum-type wheat varieties on Lactobacillus and Bifidobacterium strains. J Sci Food Agri 92, 2133–2140.
46. Minokoshi, Y., Kim, Y.B., Peroni, O.D., Fryer, L.G., Muller, C., Carling, D. and Kahn, B.B. (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415, 339–343.
47. Moens, F., Weckx, S. and De Vuyst, L. (2016) Bifidobacterial inulin-type fructan degradation capacity determines cross-feeding interactions between bifidobacteria and Faecalibacterium prausnitzii. Int J Food Microbiol 231, 76–85.
48. Moens, F., Verce, M. and De Vuyst, L. (2017) Lactate- and acetate-based cross-feeding interactions between selected strains of lactobacilli, bifidobacteria and colon bacteria in the presence of inulin-type fructans. Int J Food Microbiol 241, 225–236.
49. Morrison, D.J., Mackay, W.G., Edwards, C.A., Preston, T., Dodson, B. and Weaver, L.T. (2006) Butyrate production from oligofructose fermentation by the human faecal flora: what is the contribution of extracellular acetate and lactate? Brit J Nutr 96, 570–577.
50. Nakamura, T., Shimbata, T., Vrinten, P., Saito, M., Yonemaru, J., Seto, Y., Yahuda, H. and Takahama, M. (2006) Sweet wheat. Genes Genet Sys 81, 361–365.
51. Neyrinck, A.M., Possemiers, S., Druart, C., Van de Wiele, T., De Backer, F., Cani, P.D., Larondelle, Y. and Delzenne, N.M. (2011) Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, roseburia and bacteroides/prevotella in diet-induced obese mice. PLoS ONE 6, e20944.
52. Parkar, S.G., Simmons, L., Herath, T.D., Phipps, J.E., Trower, T.M., Hedderley, D.I. and Ingram, J.R. (2017) Evaluation of the prebiotic potential of five kiwifruit cultivars after simulated gastrointestinal digestion and fermentation with human faecal bacteria. IntJ Food Sci Technol 53, 1203–1210.
53. Paturi, G., Butts, C.A., Bentley-Hewitt, K.L. and Ansell, J. (2014) Influence of green and gold kiwifruit on indices of large bowel function in healthy rats. J Food Sci 79, H1611–H1620.
54. Ramirez-Farias, C., Slezak, K., Fuller, Z., Duncan, A., Holtrop, G. and Louis, P. (2009) Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii. Brit J Nutr 101, 541–550.
55. Rivière, A., Gagnon, M., Weckx, S., Roy, D. and De Vuyst, L. (2015) Mutual cross-feeding interactions between Bifidobacterium longum subsp. longum NCC2705 and Eubacterium rectale ATCC 33656 explain the bifidogenic and butyrogenic effects of arabinoxylan oligosaccharides. Appl Environ Microbiol 81, 7767–7781.
56. Rivière, A., Selak, M., Lantin, D., Leroy, F. and De Vuyst, L. (2016) Bifidobacteria and butyrate-producing colon bacteria: importance and strategies for their stimulation in the human gut. Front Microbiol 7, 979.
57. Roberfroid, M., Gibson, G.R., Hoyles, L., McCartney, A.L., Rastall, R., Rowland, I., Wolvers, D., Watzl, B. et al. (2010) Prebiotic effects: metabolic and health benefits. Brit J Nutr 104(S2), 1–63.
58. Roediger, W.E. (1982) Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterol 83, 424–429.
59. Ruppin, H., Bar-Meir, S., Soergel, K.H., Wood, C.M. and Schmitt, M.G. Jr (1980) Absorption of short-chain fatty acids by the colon. Gastroenterology 78, 1500–1507.
60. Scott, K.P., Martin, J.C., Duncan, S.H. and Flint, H.J. (2014) Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro. FEMS Microbiol Ecol 87, 30–40.
61. Selak, M., Rivière, A., Moens, F., Van den Abbeele, P., Geirnaert, A., Rogelj, I., Leroy, F. and De Vuyst, L. (2016) Inulin-type fructan fermentation by bifidobacteria depends on the strain rather than the species and region in the human intestine. Appl Microbiol Biotechnol 100, 4097–4107.
62. Sims, I.M. and Monro, J.A. (2013) Fiber: composition, structures, and functional properties. In Advances in Food and Nutrition Research, Vol 68. eds. Boland, M. and Moughan, P.J., pp 81–99. Cambridge, MA: Academic Press.
63. Smith, S.C., Choy, R., Johnson, S.K., Hall, R.S., Wildeboer-Veloo, A.C.M. and Welling, G.W. (2006) Lupin kernel fiber consumption modifies faecal microbiota in healthy men as determined by rRNA gene fluorescent in situ hybridization. Eur J Nutr 45, 335–341.
64. Sumio, T.A. and Jharrod, M. (2014) Japan’s Health Food Market: Background, Trends and Recommendations. Available from: Global Agricultural Information Network Report of USDA Foreign Agricultural Service. https://gain.fas.usda.gov/Recent%20GAIN%20Publications/Functional%20Food%20Report_Tokyo%20ATO_Japan_8-13-2014.pdf.
65. Vulevic, J., Juric, A., Tzortzis, G. and Gibson, G.R. (2013) A mixture of trans-galactooligosaccharides reduces markers of metabolic syndrome and modulates the faecal microbiota and immune function of overweight adults. J Nutr 143, 324–331.
66. Vulevic, J., Juric, A., Walton, G.E., Claus, S.P., Tzortzis, G., Toward, R.E. and Gibson, G.R. (2015) Influence of galacto-oligosaccharide mixture (B-GOS) on gut microbiota, immune parameters and metabonomics in elderly persons. Brit J Nutr 114, 586–595.
67. Wolever, T.M., Spadafora, P. and Eshuis, H. (1991) Interaction between colonic acetate and propionate in humans. Am J Clin Nutr 53, 681–687.
68. Wright, R.S., Anderson, J.W. and Bridges, S.R. (1990) Propionate inhibits hepatocyte lipid synthesis. Proc Soci Exp Biol Med 195, 26–29.
69. Zaman, S.A. and Sarbini, S.R. (2016) The potential of resistant starch as a prebiotic. Crit Rev Biotechnol 36, 578–584.