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Volumn 28, Issue 5, 2019, Pages 858-874

Genetic influences on susceptibility to rheumatoid arthritis in African-Americans

(15)  Laufer, Vincent A a   Tiwari, Hemant K b   Reynolds, Richard J a   Danila, Maria I a   Wang, Jelai b   Edberg, Jeffrey C a   Kimberly, Robert P a   Kottyan, Leah C c   Harley, John B c,d   Mikuls, Ted R e,f   Gregersen, Peter K g   Absher, Devin M h   Langefeld, Carl D i   Arnett, Donna K j   Bridges, S Louis a  


Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ETANERCEPT; GLYPICAN; GLYPICAN 5; HLA DRB1 ANTIGEN; METHOTREXATE; STAT4 PROTEIN; TRANSCRIPTION FACTOR E2F6; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG;

EID: 85066303169     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddy395     Document Type: Article
Times cited : (49)

References (99)
  • 1
    • 84861808622 scopus 로고    scopus 로고
    • Epidemiology and genetics of rheumatoid arthritis
    • Silman, A.J. and Pearson, J.E. (2002) Epidemiology and genetics of rheumatoid arthritis. Arthritis Res., 4 (Suppl.) 3, S265-S272.
    • (2002) Arthritis Res. , vol.4 , pp. S265-S272
    • Silman, A.J.1    Pearson, J.E.2
  • 2
    • 84855172814 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis
    • McInnes, I.B. and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. N. Engl. J. Med., 365, 2205-2219.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 2205-2219
    • McInnes, I.B.1    Schett, G.2
  • 4
    • 84874721851 scopus 로고    scopus 로고
    • Genetics and epigenetics of rheumatoid arthritis
    • Viatte, S., Plant,D. and Raychaudhuri, S. (2013) Genetics and epigenetics of rheumatoid arthritis. Nat. Rev. Rheumatol., 9, 141-153.
    • (2013) Nat. Rev. Rheumatol. , vol.9 , pp. 141-153
    • Viatte, S.1    Plant, D.2    Raychaudhuri, S.3
  • 5
    • 78649831816 scopus 로고    scopus 로고
    • Most common singlenucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans
    • 3453
    • Hughes, L.B., Reynolds, R.J., Brown, E.E., Kelley, J.M., Thomson, B., Conn, D.L., Jonas, B.L., Westfall, A.O., Padilla, M.A., Callahan, L.F. et al. (2010) Most common singlenucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans. Arthritis Rheum., 62, 3547-3453.
    • (2010) Arthritis Rheum. , vol.62 , pp. 3547
    • Hughes, L.B.1    Reynolds, R.J.2    Brown, E.E.3    Kelley, J.M.4    Thomson, B.5    Conn, D.L.6    Jonas, B.L.7    Westfall, A.O.8    Padilla, M.A.9    Callahan, L.F.10
  • 7
    • 0017878054 scopus 로고
    • Association of the B-cell alloantigen DRw4 with rheumatoid arthritis
    • Stastny, P. (1978) Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N. Engl. J. Med., 298, 869-871.
    • (1978) N. Engl. J. Med. , vol.298 , pp. 869-871
    • Stastny, P.1
  • 9
    • 58249097071 scopus 로고    scopus 로고
    • Different patterns of associations with anti-citrullinated protein antibody-positive and anticitrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region
    • Ding, B., Padyukov, L., Lundstrom, E., Seielstad, M., Plenge, R.M., Oksenberg, J.R., Gregersen, P.K., Alfredsson, L. and Klareskog, L. (2009) Different patterns of associations with anti-citrullinated protein antibody-positive and anticitrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis Rheum., 60, 30-38.
    • (2009) Arthritis Rheum. , vol.60 , pp. 30-38
    • Ding, B.1    Padyukov, L.2    Lundstrom, E.3    Seielstad, M.4    Plenge, R.M.5    Oksenberg, J.R.6    Gregersen, P.K.7    Alfredsson, L.8    Klareskog, L.9
  • 10
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen, P.K., Silver, J. and Winchester, R.J. (1987) The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum., 30, 1205-1213.
    • (1987) Arthritis Rheum. , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 13
    • 84912020278 scopus 로고    scopus 로고
    • HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: Hierarchical classification systems, amino acid positions, and residues
    • Reynolds, R.J., Ahmed, A.F., Danila, M.I., Hughes, L.B., Gregersen, P.K., Raychaudhuri, S., Plenge, R.M. and Bridges, S.L. Jr (2014) HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues. Arthritis Rheumatol., 66, 3274-3282.
    • (2014) Arthritis Rheumatol. , vol.66 , pp. 3274-3282
    • Reynolds, R.J.1    Ahmed, A.F.2    Danila, M.I.3    Hughes, L.B.4    Gregersen, P.K.5    Raychaudhuri, S.6    Plenge, R.M.7    Bridges, S.L.8
  • 14
    • 84856070217 scopus 로고    scopus 로고
    • Emerging patterns of genetic overlap across autoimmune disorders
    • Richard-Miceli, C. and Criswell, L.A. (2012) Emerging patterns of genetic overlap across autoimmune disorders. Genome Med., 4, 6-14.
    • (2012) Genome Med. , vol.4 , pp. 6-14
    • Richard-Miceli, C.1    Criswell, L.A.2
  • 15
    • 82355170584 scopus 로고    scopus 로고
    • Transethnic meta-analysis of genomewide association studies
    • Morris, A.P. (2011) Transethnic meta-analysis of genomewide association studies. Genet. Epidemiol., 35, 809-822.
    • (2011) Genet. Epidemiol. , vol.35 , pp. 809-822
    • Morris, A.P.1
  • 16
    • 84895868553 scopus 로고    scopus 로고
    • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan, A., Go, M.J., Zhang, W., Below, J.E., Gaulton, K.J. et al. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet., 46, 234-244.
    • (2014) Nat. Genet. , vol.46 , pp. 234-244
    • Mahajan, A.1    Go, M.J.2    Zhang, W.3    Below, J.E.4    Gaulton, K.J.5
  • 18
    • 84868261826 scopus 로고    scopus 로고
    • Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease
    • Viatte, S., Flynn, E., Lunt, M., Barnes, J., Singwe-Ngandeu, M., Bas, S., Barton, A. and Gabay, C. (2012) Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease. Arthritis Res. Ther., 14, R239-R245.
    • (2012) Arthritis Res. Ther. , vol.14 , pp. R239-R245
    • Viatte, S.1    Flynn, E.2    Lunt, M.3    Barnes, J.4    Singwe-Ngandeu, M.5    Bas, S.6    Barton, A.7    Gabay, C.8
  • 20
    • 85024845927 scopus 로고    scopus 로고
    • Integrative approaches to understanding the pathogenic role of genetic variation in rheumatic diseases
    • Laufer, V.A., Chen, J.Y., Langefeld, C.D. and Bridges, S.L. Jr (2017) Integrative approaches to understanding the pathogenic role of genetic variation in rheumatic diseases. Rheum. Dis. Clin. North Am., 43, 449-466.
    • (2017) Rheum. Dis. Clin. North Am. , vol.43 , pp. 449-466
    • Laufer, V.A.1    Chen, J.Y.2    Langefeld, C.D.3    Bridges, S.L.4
  • 22
    • 84938982145 scopus 로고    scopus 로고
    • Leveraging functionalannotation data in trans-ethnic fine-mapping studies
    • Kichaev, G. and Pasaniuc, B. (2015) Leveraging functionalannotation data in trans-ethnic fine-mapping studies. Am. J. Hum. Genet., 97, 260-271.
    • (2015) Am. J. Hum. Genet. , vol.97 , pp. 260-271
    • Kichaev, G.1    Pasaniuc, B.2
  • 24
    • 84869232820 scopus 로고    scopus 로고
    • Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping
    • Ong, R.T., Wang, X., Liu, X. and Teo, Y.Y. (2012) Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping. Eur. J. Hum. Genet., 20, 1300-1307.
    • (2012) Eur. J. Hum. Genet. , vol.20 , pp. 1300-1307
    • Ong, R.T.1    Wang, X.2    Liu, X.3    Teo, Y.Y.4
  • 25
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium (2005) A haplotype map of the human genome. Nature, 437, 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 27
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han, B. and Eskin, E. (2011) Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet., 88, 586-598.
    • (2011) Am. J. Hum. Genet. , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 28
    • 84859246571 scopus 로고    scopus 로고
    • Interpreting meta-analyses of genome-wide association studies
    • Han, B. and Eskin, E. (2012) Interpreting meta-analyses of genome-wide association studies. PLoS Genet., 8, e1002555.
    • (2012) PLoS Genet. , vol.8
    • Han, B.1    Eskin, E.2
  • 30
    • 84978393978 scopus 로고    scopus 로고
    • ForestPMPlot: A f lexible tool for visualizing heterogeneity between studies in meta-analysis
    • Kang, E.Y., Park, Y., Li, X., Segrè, A.V., Han, B. and Eskin, E. (2016) ForestPMPlot: a f lexible tool for visualizing heterogeneity between studies in meta-analysis. G3 (Bethesda), 6, 1793-1798.
    • (2016) G. 3 (Bethesda) , vol.6 , pp. 1793-1798
    • Kang, E.Y.1    Park, Y.2    Li, X.3    Segrè, A.V.4    Han, B.5    Eskin, E.6
  • 33
    • 85046495237 scopus 로고    scopus 로고
    • Transethnic differences in GWAS signals: A simulation study
    • Zanetti, D. and Weale, M.E. (2018) Transethnic differences in GWAS signals: a simulation study. Ann. Hum. Genet., 82, 280-286.
    • (2018) Ann. Hum. Genet. , vol.82 , pp. 280-286
    • Zanetti, D.1    Weale, M.E.2
  • 35
    • 50549083074 scopus 로고    scopus 로고
    • Curses - Winner's and otherwise - In genetic epidemiology
    • Kraft, P. (2008) Curses - winner's and otherwise - in genetic epidemiology. Epidemiology, 19, 649-651.
    • (2008) Epidemiology , vol.19 , pp. 649-651
    • Kraft, P.1
  • 37
    • 84959315811 scopus 로고    scopus 로고
    • Apolipoprotein L1 and kidney disease in African Americans
    • Friedman, D.J. and Pollak, M.R. (2016) Apolipoprotein L1 and kidney disease in African Americans. Trends Endocrinol. Metab., 27, 204-215.
    • (2016) Trends Endocrinol. Metab. , vol.27 , pp. 204-215
    • Friedman, D.J.1    Pollak, M.R.2
  • 40
    • 84858999318 scopus 로고    scopus 로고
    • A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: Results from the Norfolk Arthritis Register
    • Plant, D., Farragher, T., Flynn, E.,Martin, P., Eyre, S., Bunn, D., Worthington, J., Symmons, D., Barton, A. and Thomson, W. (2012) A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: results from the Norfolk Arthritis Register. Pharmacogenomics J., 12, 128-133.
    • (2012) Pharmacogenomics J. , vol.12 , pp. 128-133
    • Plant, D.1    Farragher, T.2    Flynn, E.3    Martin, P.4    Eyre, S.5    Bunn, D.6    Worthington, J.7    Symmons, D.8    Barton, A.9    Thomson, W.10
  • 41
    • 84927177410 scopus 로고    scopus 로고
    • Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
    • Bank S., Andersen, P.S., Burisch, J., Pedersen, N., Roug, S., Galsgaard, J., Turino, S.Y., Brodersen, J.B., Rashid, S., Rasmussen, B.K. et al. (2014) Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. Pharmacogenomics J., 14, 526-534.
    • (2014) Pharmacogenomics J. , vol.14 , pp. 526-534
    • Bank, S.1    Andersen, P.S.2    Burisch, J.3    Pedersen, N.4    Roug, S.5    Galsgaard, J.6    Turino, S.Y.7    Brodersen, J.B.8    Rashid, S.9    Rasmussen, B.K.10
  • 42
    • 84971284049 scopus 로고    scopus 로고
    • A prospective pharmacogenomic study of Crohn's disease patients during routine therapy with anti-TNFalpha drug adalimumab: Contribution of ATG5, NFKB1, and CRP genes to pharmacodynamic variability
    • Dezelak, M., Repnik, K., Koder, S., Ferkolj, I. and Potočnik, U. (2016) A prospective pharmacogenomic study of Crohn's disease patients during routine therapy with anti-TNFalpha drug adalimumab: contribution of ATG5, NFKB1, and CRP genes to pharmacodynamic variability. OMICS, 20, 296-309.
    • (2016) OMICS , vol.20 , pp. 296-309
    • Dezelak, M.1    Repnik, K.2    Koder, S.3    Ferkolj, I.4    Potočnik, U.5
  • 43
    • 84937605375 scopus 로고    scopus 로고
    • Paradoxical psoriasiform reactions to anti-TNFalpha drugs are associated with genetic polymorphisms in patients with psoriasis
    • 240
    • Cabaleiro, T., Prieto-Pérez, R., Navarro, R., Solano, G., Román, M., Ochoa, D., Abad-Santos, F. and Daudén, E. (2016) Paradoxical psoriasiform reactions to anti-TNFalpha drugs are associated with genetic polymorphisms in patients with psoriasis. Pharmacogenomics J., 16, 336-240.
    • (2016) Pharmacogenomics J. , vol.16 , pp. 336
    • Cabaleiro, T.1    Prieto-Pérez, R.2    Navarro, R.3    Solano, G.4    Román, M.5    Ochoa, D.6    Abad-Santos, F.7    Daudén, E.8
  • 44
    • 85010303854 scopus 로고    scopus 로고
    • Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 genes are associated with the response to TNF inhibitors in patients with rheumatoid arthritis
    • Conigliaro, P., Ciccacci, C., Politi, C., Triggianese, P., Rufini, S., Kroegler, B., Perricone, C., Latini, A., Novelli, G., Borgiani, P. et al. (2017) Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 genes are associated with the response to TNF inhibitors in patients with rheumatoid arthritis. PLoS One, 12, e0169956.
    • (2017) PLoS One , vol.12
    • Conigliaro, P.1    Ciccacci, C.2    Politi, C.3    Triggianese, P.4    Rufini, S.5    Kroegler, B.6    Perricone, C.7    Latini, A.8    Novelli, G.9    Borgiani, P.10
  • 48
    • 84873193482 scopus 로고    scopus 로고
    • Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3- CD4+ CD25- T cells modulates TLR-4 induced TNF-alpha production
    • Boswell, S., Pathan, A.A., Pereira, S.P., Williams, R. and Behboudi, S. (2013) Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3- CD4+ CD25- T cells modulates TLR-4 induced TNF-alpha production. Immunobiology, 218, 427-434.
    • (2013) Immunobiology , vol.218 , pp. 427-434
    • Boswell, S.1    Pathan, A.A.2    Pereira, S.P.3    Williams, R.4    Behboudi, S.5
  • 49
    • 84966605759 scopus 로고    scopus 로고
    • GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/beta-catenin signaling in lung adenocarcinoma
    • Yuan, S., Yu, Z., Liu, Q., Zhang, M., Xiang, Y., Wu, N., Wu, L., Hu, Z., Xu, B., Cai, T. et al. (2016) GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/beta-catenin signaling in lung adenocarcinoma. Oncogene, 35, 6120-6131.
    • (2016) Oncogene , vol.35 , pp. 6120-6131
    • Yuan, S.1    Yu, Z.2    Liu, Q.3    Zhang, M.4    Xiang, Y.5    Wu, N.6    Wu, L.7    Hu, Z.8    Xu, B.9    Cai, T.10
  • 54
    • 84903548291 scopus 로고    scopus 로고
    • Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis
    • Aterido, A., Palacio,C., Marsal, S.,Avila,G. and Julià,A. (2014) Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis. PLoS One, 9, e100690.
    • (2014) PLoS One , vol.9
    • Aterido, A.1    Palacio, C.2    Marsal, S.3    Avila, G.4    Julià, A.5
  • 56
    • 85013957711 scopus 로고    scopus 로고
    • Immunopathogenesis of rheumatoid arthritis
    • Firestein, G., and McInnes, I.B. (2017) Immunopathogenesis of rheumatoid arthritis. Immunity, 46, 183-196.
    • (2017) Immunity , vol.46 , pp. 183-196
    • Firestein, G.1    McInnes, I.B.2
  • 57
    • 84860390022 scopus 로고    scopus 로고
    • Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: Novel insights into autoantigen selection in rheumatoid arthritis
    • Darrah, E., Rosen, A., Giles, J.T. and Andrade, F. (2012) Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis. Ann. Rheum. Dis., 71, 92-98.
    • (2012) Ann. Rheum. Dis. , vol.71 , pp. 92-98
    • Darrah, E.1    Rosen, A.2    Giles, J.T.3    Andrade, F.4
  • 59
    • 84965081767 scopus 로고    scopus 로고
    • Increased levels of peptidylarginine deiminase 2 in synovial f luid fromanti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers
    • Damgaard, D., Senolt, L. and Nielsen, C.H. (2016) Increased levels of peptidylarginine deiminase 2 in synovial f luid fromanti-CCP-positive rheumatoid arthritis patients: association with disease activity and inflammatory markers. Rheumatology (Oxford), 55, 918-927.
    • (2016) Rheumatology (Oxford) , vol.55 , pp. 918-927
    • Damgaard, D.1    Senolt, L.2    Nielsen, C.H.3
  • 60
    • 85011615063 scopus 로고    scopus 로고
    • Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation
    • Bawadekar, M., Shim, D., Johnson, C.J., Warner, T.F., Rebernick, R., Damgaard, D., Nielsen, C.H., Pruijn, G.J.M., Nett, J.E. and Shelef, M.A. (2017) Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation. J. Autoimmun., 80, 39-47.
    • (2017) J. Autoimmun. , vol.80 , pp. 39-47
    • Bawadekar, M.1    Shim, D.2    Johnson, C.J.3    Warner, T.F.4    Rebernick, R.5    Damgaard, D.6    Nielsen, C.H.7    Pruijn, G.J.M.8    Nett, J.E.9    Shelef, M.A.10
  • 64
    • 84866893076 scopus 로고    scopus 로고
    • Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese
    • Myouzen, K., Kochi, Y., Okada, Y., Terao, C., Suzuki, A., Ikari, K., Tsunoda, T., Takahashi, A., Kubo, M., Taniguchi, A. et al. (2012) Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese. PLoS Genet., 8, e1002949-e1002962.
    • (2012) PLoS Genet. , vol.8 , pp. e1002949-e1002962
    • Myouzen, K.1    Kochi, Y.2    Okada, Y.3    Terao, C.4    Suzuki, A.5    Ikari, K.6    Tsunoda, T.7    Takahashi, A.8    Kubo, M.9    Taniguchi, A.10
  • 65
    • 84952768681 scopus 로고    scopus 로고
    • Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line
    • Imamura, H., Yoshina, S., Ikari, K., Miyazawa, K., Momohara, S. and Mitani, S. (2016) Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line. Mod. Rheumatol., 26, 507-516.
    • (2016) Mod. Rheumatol. , vol.26 , pp. 507-516
    • Imamura, H.1    Yoshina, S.2    Ikari, K.3    Miyazawa, K.4    Momohara, S.5    Mitani, S.6
  • 68
    • 84955332058 scopus 로고    scopus 로고
    • Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes
    • de Jong, V.M., Zaldumbide, A., van der Slik, A.R., Laban, S., Koeleman, B.P. and Roep, B.O. (2016) Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes. Genes Immun., 17, 75-78.
    • (2016) Genes Immun. , vol.17 , pp. 75-78
    • De Jong, V.M.1    Zaldumbide, A.2    Van Der Slik, A.R.3    Laban, S.4    Koeleman, B.P.5    Roep, B.O.6
  • 69
    • 84875463042 scopus 로고    scopus 로고
    • Molecular mechanisms of T cell co-stimulation and co-inhibition
    • Chen, L. and Flies, D.B. (2013) Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol., 13, 227-242.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 227-242
    • Chen, L.1    Flies, D.B.2
  • 71
    • 84984788469 scopus 로고    scopus 로고
    • EBV nuclear antigen 3Cmediates regulation of E2F6 to inhibit E2F1 transcription and promote cell proliferation
    • Pei, Y. (2016) EBV nuclear antigen 3Cmediates regulation of E2F6 to inhibit E2F1 transcription and promote cell proliferation. PLoS Pathog., 12, e1005844-e1005868.
    • (2016) PLoS Pathog. , vol.12 , pp. e1005844-e1005868
    • Pei, Y.1
  • 72
    • 84928641788 scopus 로고    scopus 로고
    • Expression of interferon-γ receptor genes in PBMCs is associated with rheumatoid arthritis and its radiographic severity in African Americans
    • Tang, Q., Danila, M.I., Cui, X., Parks, L., Baker, B.J., Reynolds, R.J., Raman, C., Wanseck, K.C., Redden, D.T., Johnson, M.R. et al. (2015) Expression of interferon-γ receptor genes in PBMCs is associated with rheumatoid arthritis and its radiographic severity in African Americans. Arthritis Rheumatol., 67, 1165-1170.
    • (2015) Arthritis Rheumatol. , vol.67 , pp. 1165-1170
    • Tang, Q.1    Danila, M.I.2    Cui, X.3    Parks, L.4    Baker, B.J.5    Reynolds, R.J.6    Raman, C.7    Wanseck, K.C.8    Redden, D.T.9    Johnson, M.R.10
  • 73
    • 32344453016 scopus 로고    scopus 로고
    • IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes
    • Regis, G., Conti, L., Boselli, D. and Novelli, F. (2006) IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes. Trends Immunol., 27, 96-101.
    • (2006) Trends Immunol. , vol.27 , pp. 96-101
    • Regis, G.1    Conti, L.2    Boselli, D.3    Novelli, F.4
  • 74
    • 0030889207 scopus 로고    scopus 로고
    • The IFN gamma receptor: A paradigm for cytokine receptor signaling
    • Bach, E.A., Aguet, M. and Schreiber, R.D. (1997) The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol., 15, 563-591.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 82
    • 84988908932 scopus 로고    scopus 로고
    • Insights and implications of the VA Rheumatoid Arthritis Registry
    • Mikuls, T.R., Kerr,G.S., and Cannon,G.W. (2015) Insights and implications of the VA Rheumatoid Arthritis Registry. Fed. Pract, 32, 24-29.
    • (2015) Fed. Pract , vol.32 , pp. 24-29
    • Mikuls, T.R.1    Kerr, G.S.2    Cannon, G.W.3
  • 83
    • 34447503679 scopus 로고    scopus 로고
    • The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis
    • Mikuls, T.R., Kazi, S., Cipher, D., Hooker, R., Kerr, G.S., Richards, J.S. and Cannon, G.W. (2007) The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis. J. Rheumatol., 34, 1480-1484.
    • (2007) J. Rheumatol. , vol.34 , pp. 1480-1484
    • Mikuls, T.R.1    Kazi, S.2    Cipher, D.3    Hooker, R.4    Kerr, G.S.5    Richards, J.S.6    Cannon, G.W.7
  • 85
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A.L., Patterson, N.J., Plenge, R.M., Weinblatt, M.E., Shadick, N.A. and Reich, D. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet., 38, 904-909.
    • (2006) Nat. Genet. , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 86
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N., Donnelly, P. and Marchini, J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
    • (2009) PLoS Genet. , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 87
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet., 39, 906-913.
    • (2007) Nat. Genet. , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 88
    • 42249087793 scopus 로고    scopus 로고
    • Estimation of significance thresholds for genomewide association scans
    • Dudbridge, F. and Gusnanto, A. (2008) Estimation of significance thresholds for genomewide association scans. Genet. Epidemiol., 32, 227-234.
    • (2008) Genet. Epidemiol. , vol.32 , pp. 227-234
    • Dudbridge, F.1    Gusnanto, A.2
  • 89
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch, N. and Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science, 273, 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 90
    • 85006307101 scopus 로고    scopus 로고
    • A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy
    • Wang, Z., Sun, Y., Fu, X., Yu, G., Wang, C., Bao, F., Yue, Z., Li, J., Sun, L., Irwanto, A. et al. (2016) A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy. Nat. Commun., 7, 13760-13767.
    • (2016) Nat. Commun. , vol.7 , pp. 13760-13767
    • Wang, Z.1    Sun, Y.2    Fu, X.3    Yu, G.4    Wang, C.5    Bao, F.6    Yue, Z.7    Li, J.8    Sun, L.9    Irwanto, A.10
  • 91
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis ismore efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol, A.D., Scott, L.J., Abecasis, G.R. and Boehnke, M. (2006) Joint analysis ismore efficient than replication-based analysis for two-stage genome-wide association studies. Nat. Genet., 38, 209-213.
    • (2006) Nat. Genet. , vol.38 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 92
    • 26444433586 scopus 로고
    • Bayesian statistical inference for psychological research
    • Edwards, W., Lindman, H. and Savage, L.J. (1963) Bayesian statistical inference for psychological research. Psychol. Rev., 70, 193-242.
    • (1963) Psychol. Rev. , vol.70 , pp. 193-242
    • Edwards, W.1    Lindman, H.2    Savage, L.J.3
  • 97
    • 84891697734 scopus 로고    scopus 로고
    • Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
    • Corradin, O., Saiakhova, A., Akhtar-Zaidi, B., Myeroff, L., Willis, J., Cowper-Sal lari, R., Lupien, M. and Markowitz, S. (2014) Scacheri PC. Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Res., 24, 1-13.
    • (2014) Genome Res. , vol.24 , pp. 1-13
    • Corradin, O.1    Saiakhova, A.2    Akhtar-Zaidi, B.3    Myeroff, L.4    Willis, J.5    Cowper-Sal Lari, R.6    Lupien, M.7    Markowitz, S.8    Scacheri, P.C.9
  • 98
    • 77955425717 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios
    • Bokor, S., Dumont, J., Spinneker, A., Gonzalez-Gross, M., Nova, E.,Widhalm, K.,Moschonis, G., Stehle, P., Amouyel, P., De Henauw, S. et al. (2010) Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J. Lipid Res., 51, 2325-2333.
    • (2010) J. Lipid Res. , vol.51 , pp. 2325-2333
    • Bokor, S.1    Dumont, J.2    Spinneker, A.3    Gonzalez-Gross, M.4    Nova, E.5    Widhalm, K.6    Moschonis, G.7    Stehle, P.8    Amouyel, P.9    De Henauw, S.10


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