-
1
-
-
84861808622
-
Epidemiology and genetics of rheumatoid arthritis
-
Silman, A.J. and Pearson, J.E. (2002) Epidemiology and genetics of rheumatoid arthritis. Arthritis Res., 4 (Suppl.) 3, S265-S272.
-
(2002)
Arthritis Res.
, vol.4
, pp. S265-S272
-
-
Silman, A.J.1
Pearson, J.E.2
-
2
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes, I.B. and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. N. Engl. J. Med., 365, 2205-2219.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
3
-
-
84894288992
-
Genetics of rheumatoid arthritis contributes to biology and drug discovery
-
Okada,Y.,Wu,D., Trynka,G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S. et al. (2014) Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature, 506, 376-381.
-
(2014)
Nature
, vol.506
, pp. 376-381
-
-
Okada, Y.1
Wu, D.2
Trynka, G.3
Raj, T.4
Terao, C.5
Ikari, K.6
Kochi, Y.7
Ohmura, K.8
Suzuki, A.9
Yoshida, S.10
-
4
-
-
84874721851
-
Genetics and epigenetics of rheumatoid arthritis
-
Viatte, S., Plant,D. and Raychaudhuri, S. (2013) Genetics and epigenetics of rheumatoid arthritis. Nat. Rev. Rheumatol., 9, 141-153.
-
(2013)
Nat. Rev. Rheumatol.
, vol.9
, pp. 141-153
-
-
Viatte, S.1
Plant, D.2
Raychaudhuri, S.3
-
5
-
-
78649831816
-
Most common singlenucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans
-
3453
-
Hughes, L.B., Reynolds, R.J., Brown, E.E., Kelley, J.M., Thomson, B., Conn, D.L., Jonas, B.L., Westfall, A.O., Padilla, M.A., Callahan, L.F. et al. (2010) Most common singlenucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans. Arthritis Rheum., 62, 3547-3453.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3547
-
-
Hughes, L.B.1
Reynolds, R.J.2
Brown, E.E.3
Kelley, J.M.4
Thomson, B.5
Conn, D.L.6
Jonas, B.L.7
Westfall, A.O.8
Padilla, M.A.9
Callahan, L.F.10
-
6
-
-
85028362756
-
Dense genotyping of immune-related regions identifies loci for rheumatoid arthritis risk and damage in African Americans
-
Danila, M.I., Laufer, V.A., Reynolds, R.J., Yan, Q., Liu, N., Gregersen, P.K., Lee, A.,Kern, M., Langefeld,C.D., Arnett,D.K. et al. (2017) Dense genotyping of immune-related regions identifies loci for rheumatoid arthritis risk and damage in African Americans. Mol. Med., 23, 177-187.
-
(2017)
Mol. Med.
, vol.23
, pp. 177-187
-
-
Danila, M.I.1
Laufer, V.A.2
Reynolds, R.J.3
Yan, Q.4
Liu, N.5
Gregersen, P.K.6
Lee, A.7
Kern, M.8
Langefeld, C.D.9
Arnett, D.K.10
-
7
-
-
0017878054
-
Association of the B-cell alloantigen DRw4 with rheumatoid arthritis
-
Stastny, P. (1978) Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N. Engl. J. Med., 298, 869-871.
-
(1978)
N. Engl. J. Med.
, vol.298
, pp. 869-871
-
-
Stastny, P.1
-
8
-
-
39749129030
-
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture
-
Hughes, L.B., Laufer, V.A., Reynolds, R.J., Yan, Q., Liu, N., Gregersen, P.K., Lee, A.,Kern, M., Langefeld,C.D., Arnett,D.K. and Bridges, S.L. Jr (2008) The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum., 58, 349-358.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 349-358
-
-
Hughes, L.B.1
Laufer, V.A.2
Reynolds, R.J.3
Yan, Q.4
Liu, N.5
Gregersen, P.K.6
Lee, A.7
Kern, M.8
Langefeld, C.D.9
Arnett, D.K.10
Bridges, S.L.11
-
9
-
-
58249097071
-
Different patterns of associations with anti-citrullinated protein antibody-positive and anticitrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region
-
Ding, B., Padyukov, L., Lundstrom, E., Seielstad, M., Plenge, R.M., Oksenberg, J.R., Gregersen, P.K., Alfredsson, L. and Klareskog, L. (2009) Different patterns of associations with anti-citrullinated protein antibody-positive and anticitrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis Rheum., 60, 30-38.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 30-38
-
-
Ding, B.1
Padyukov, L.2
Lundstrom, E.3
Seielstad, M.4
Plenge, R.M.5
Oksenberg, J.R.6
Gregersen, P.K.7
Alfredsson, L.8
Klareskog, L.9
-
10
-
-
0023500817
-
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
-
Gregersen, P.K., Silver, J. and Winchester, R.J. (1987) The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum., 30, 1205-1213.
-
(1987)
Arthritis Rheum.
, vol.30
, pp. 1205-1213
-
-
Gregersen, P.K.1
Silver, J.2
Winchester, R.J.3
-
11
-
-
84862776511
-
Five amino acids in three HLA proteins explainmost of the association between MHC and seropositive rheumatoid arthritis
-
Raychaudhuri, S., Sandor, C., Stahl, E.A., Freudenberg, J., Lee, H.S., Jia, X., Alfredsson, L., Padyukov, L., Klareskog, L., Worthington, J. et al. (2012) Five amino acids in three HLA proteins explainmost of the association between MHC and seropositive rheumatoid arthritis. Nat. Genet., 44, 291-296.
-
(2012)
Nat. Genet.
, vol.44
, pp. 291-296
-
-
Raychaudhuri, S.1
Sandor, C.2
Stahl, E.A.3
Freudenberg, J.4
Lee, H.S.5
Jia, X.6
Alfredsson, L.7
Padyukov, L.8
Klareskog, L.9
Worthington, J.10
-
12
-
-
84928731411
-
Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response
-
Viatte, S., Plant,D.,Han, B., Fu, B., Yarwood,A., Thomson,W., Symmons, D.P.,Worthington, J., Young, A., Hyrich, K.L. et al. (2015) Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response. JAMA, 313, 1645-1656.
-
(2015)
JAMA
, vol.313
, pp. 1645-1656
-
-
Viatte, S.1
Plant, D.2
Han, B.3
Fu, B.4
Yarwood, A.5
Thomson, W.6
Symmons, D.P.7
Worthington, J.8
Young, A.9
Hyrich, K.L.10
-
13
-
-
84912020278
-
HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: Hierarchical classification systems, amino acid positions, and residues
-
Reynolds, R.J., Ahmed, A.F., Danila, M.I., Hughes, L.B., Gregersen, P.K., Raychaudhuri, S., Plenge, R.M. and Bridges, S.L. Jr (2014) HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues. Arthritis Rheumatol., 66, 3274-3282.
-
(2014)
Arthritis Rheumatol.
, vol.66
, pp. 3274-3282
-
-
Reynolds, R.J.1
Ahmed, A.F.2
Danila, M.I.3
Hughes, L.B.4
Gregersen, P.K.5
Raychaudhuri, S.6
Plenge, R.M.7
Bridges, S.L.8
-
14
-
-
84856070217
-
Emerging patterns of genetic overlap across autoimmune disorders
-
Richard-Miceli, C. and Criswell, L.A. (2012) Emerging patterns of genetic overlap across autoimmune disorders. Genome Med., 4, 6-14.
-
(2012)
Genome Med.
, vol.4
, pp. 6-14
-
-
Richard-Miceli, C.1
Criswell, L.A.2
-
15
-
-
82355170584
-
Transethnic meta-analysis of genomewide association studies
-
Morris, A.P. (2011) Transethnic meta-analysis of genomewide association studies. Genet. Epidemiol., 35, 809-822.
-
(2011)
Genet. Epidemiol.
, vol.35
, pp. 809-822
-
-
Morris, A.P.1
-
16
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan, A., Go, M.J., Zhang, W., Below, J.E., Gaulton, K.J. et al. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet., 46, 234-244.
-
(2014)
Nat. Genet.
, vol.46
, pp. 234-244
-
-
Mahajan, A.1
Go, M.J.2
Zhang, W.3
Below, J.E.4
Gaulton, K.J.5
-
17
-
-
3242713277
-
A missense singlenucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.Am
-
Begovich, A.B., Carlton, V.E., Honigberg, L.A., Schrodi, S.J., Chokkalingam, A.P., Alexander, H.C., Ardlie, K.G., Huang, Q., Smith, A.M., Spoerke, J.M. et al. (2004) A missense singlenucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.Am. J. Hum. Genet., 75, 330-337.
-
(2004)
J. Hum. Genet.
, vol.75
, pp. 330-337
-
-
Begovich, A.B.1
Carlton, V.E.2
Honigberg, L.A.3
Schrodi, S.J.4
Chokkalingam, A.P.5
Alexander, H.C.6
Ardlie, K.G.7
Huang, Q.8
Smith, A.M.9
Spoerke, J.M.10
-
18
-
-
84868261826
-
Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease
-
Viatte, S., Flynn, E., Lunt, M., Barnes, J., Singwe-Ngandeu, M., Bas, S., Barton, A. and Gabay, C. (2012) Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease. Arthritis Res. Ther., 14, R239-R245.
-
(2012)
Arthritis Res. Ther.
, vol.14
, pp. R239-R245
-
-
Viatte, S.1
Flynn, E.2
Lunt, M.3
Barnes, J.4
Singwe-Ngandeu, M.5
Bas, S.6
Barton, A.7
Gabay, C.8
-
19
-
-
84921933742
-
Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans
-
Govind, N., Choudhury, A., Hodkinson, B., Ickinger, C., Frost, J., Lee, A., Gregersen, P.K., Reynolds, R.J., Bridges, S.L. Jr, Hazelhurst, S. et al. (2014) Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans. Mol. Med., 20, 341-349.
-
(2014)
Mol. Med.
, vol.20
, pp. 341-349
-
-
Govind, N.1
Choudhury, A.2
Hodkinson, B.3
Ickinger, C.4
Frost, J.5
Lee, A.6
Gregersen, P.K.7
Reynolds, R.J.8
Bridges, S.L.9
Hazelhurst, S.10
-
20
-
-
85024845927
-
Integrative approaches to understanding the pathogenic role of genetic variation in rheumatic diseases
-
Laufer, V.A., Chen, J.Y., Langefeld, C.D. and Bridges, S.L. Jr (2017) Integrative approaches to understanding the pathogenic role of genetic variation in rheumatic diseases. Rheum. Dis. Clin. North Am., 43, 449-466.
-
(2017)
Rheum. Dis. Clin. North Am.
, vol.43
, pp. 449-466
-
-
Laufer, V.A.1
Chen, J.Y.2
Langefeld, C.D.3
Bridges, S.L.4
-
21
-
-
84937035185
-
Fine mapping causal variants with an approximate Bayesian method using marginal test statistics
-
7136
-
Chen, W., Larrabee, B.R., Ovsyannikova, I.G., Kennedy, R.B., Haralambieva, I.H., Poland, G.A. and Schaid, D.J. (2015) Fine mapping causal variants with an approximate Bayesian method using marginal test statistics. Genetics, 200, 7197-7136.
-
(2015)
Genetics
, vol.200
, pp. 7197
-
-
Chen, W.1
Larrabee, B.R.2
Ovsyannikova, I.G.3
Kennedy, R.B.4
Haralambieva, I.H.5
Poland, G.A.6
Schaid, D.J.7
-
22
-
-
84938982145
-
Leveraging functionalannotation data in trans-ethnic fine-mapping studies
-
Kichaev, G. and Pasaniuc, B. (2015) Leveraging functionalannotation data in trans-ethnic fine-mapping studies. Am. J. Hum. Genet., 97, 260-271.
-
(2015)
Am. J. Hum. Genet.
, vol.97
, pp. 260-271
-
-
Kichaev, G.1
Pasaniuc, B.2
-
23
-
-
85019665555
-
Improved methods for multi-trait finemapping of pleiotropic risk loci
-
Kichaev, G., Roytman, M., Johnson, R., Eskin, E., Lindström, S., Kraft, P. and Pasaniuc, B. (2017) Improved methods for multi-trait finemapping of pleiotropic risk loci. Bioinformatics, 33, 248-255.
-
(2017)
Bioinformatics
, vol.33
, pp. 248-255
-
-
Kichaev, G.1
Roytman, M.2
Johnson, R.3
Eskin, E.4
Lindström, S.5
Kraft, P.6
Pasaniuc, B.7
-
24
-
-
84869232820
-
Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping
-
Ong, R.T., Wang, X., Liu, X. and Teo, Y.Y. (2012) Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping. Eur. J. Hum. Genet., 20, 1300-1307.
-
(2012)
Eur. J. Hum. Genet.
, vol.20
, pp. 1300-1307
-
-
Ong, R.T.1
Wang, X.2
Liu, X.3
Teo, Y.Y.4
-
25
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium (2005) A haplotype map of the human genome. Nature, 437, 1299-1320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
26
-
-
80051679387
-
The landscape of recombination in African Americans
-
Hinch, A.G., Tandon, A., Patterson, N., Song, Y., Rohland, N., Palmer, C.D., Chen, G.K., Wang, K., Buxbaum, S.G., Akylbekova, E.L. et al. (2011) The landscape of recombination in African Americans. Nature, 476, 170-175.
-
(2011)
Nature
, vol.476
, pp. 170-175
-
-
Hinch, A.G.1
Tandon, A.2
Patterson, N.3
Song, Y.4
Rohland, N.5
Palmer, C.D.6
Chen, G.K.7
Wang, K.8
Buxbaum, S.G.9
Akylbekova, E.L.10
-
27
-
-
79955860273
-
Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
-
Han, B. and Eskin, E. (2011) Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet., 88, 586-598.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 586-598
-
-
Han, B.1
Eskin, E.2
-
28
-
-
84859246571
-
Interpreting meta-analyses of genome-wide association studies
-
Han, B. and Eskin, E. (2012) Interpreting meta-analyses of genome-wide association studies. PLoS Genet., 8, e1002555.
-
(2012)
PLoS Genet.
, vol.8
-
-
Han, B.1
Eskin, E.2
-
29
-
-
84959477574
-
Significant impact of miRNA-target gene networks on genetics of human complex traits
-
Okada, Y., Muramatsu, T., Suita, N., Kanai, M., Kawakami, E., Iotchkova, V., Soranzo, N., Inazawa, J. and Tanaka, T. (2016) Significant impact of miRNA-target gene networks on genetics of human complex traits. Sci. Rep., 6, 22223.
-
(2016)
Sci. Rep.
, vol.6
, pp. 22223
-
-
Okada, Y.1
Muramatsu, T.2
Suita, N.3
Kanai, M.4
Kawakami, E.5
Iotchkova, V.6
Soranzo, N.7
Inazawa, J.8
Tanaka, T.9
-
30
-
-
84978393978
-
ForestPMPlot: A f lexible tool for visualizing heterogeneity between studies in meta-analysis
-
Kang, E.Y., Park, Y., Li, X., Segrè, A.V., Han, B. and Eskin, E. (2016) ForestPMPlot: a f lexible tool for visualizing heterogeneity between studies in meta-analysis. G3 (Bethesda), 6, 1793-1798.
-
(2016)
G. 3 (Bethesda)
, vol.6
, pp. 1793-1798
-
-
Kang, E.Y.1
Park, Y.2
Li, X.3
Segrè, A.V.4
Han, B.5
Eskin, E.6
-
31
-
-
84923326765
-
Genetic and epigenetic fine-mapping of causal autoimmune disease variants
-
Farh, K.K., Marson, A., Zhu, J., Kleinewietfeld, M., Housley, W.J., Beik, S., Shoresh, N., Whitton, H., Ryan, R.J., Shishkin, A.A. et al. (2015) Genetic and epigenetic fine-mapping of causal autoimmune disease variants. Nature, 518, 337-343.
-
(2015)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.1
Marson, A.2
Zhu, J.3
Kleinewietfeld, M.4
Housley, W.J.5
Beik, S.6
Shoresh, N.7
Whitton, H.8
Ryan, R.J.9
Shishkin, A.A.10
-
32
-
-
84877754351
-
Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance
-
Goodarzi, M.O., Guo, X., Cui, J., Jones, M.R., Haritunians, T., Xiang, A.H., Chen, Y.D., Taylor, K.D., Buchanan, T.A., Hsueh, W.A. et al. (2013) Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. Diabetologia, 56, 1282-1290.
-
(2013)
Diabetologia
, vol.56
, pp. 1282-1290
-
-
Goodarzi, M.O.1
Guo, X.2
Cui, J.3
Jones, M.R.4
Haritunians, T.5
Xiang, A.H.6
Chen, Y.D.7
Taylor, K.D.8
Buchanan, T.A.9
Hsueh, W.A.10
-
33
-
-
85046495237
-
Transethnic differences in GWAS signals: A simulation study
-
Zanetti, D. and Weale, M.E. (2018) Transethnic differences in GWAS signals: a simulation study. Ann. Hum. Genet., 82, 280-286.
-
(2018)
Ann. Hum. Genet.
, vol.82
, pp. 280-286
-
-
Zanetti, D.1
Weale, M.E.2
-
34
-
-
66249116333
-
The genetic structure and history of Africans and African Americans
-
Tishkoff, S.A., Reed, F.A., Friedlaender, F.R., Ehret, C., Ranciaro, A., Froment, A., Hirbo, J.B., Awomoyi, A.A., Bodo, J.M., Doumbo, O. et al. (2009) The genetic structure and history of Africans and African Americans. Science, 324, 1035-1044.
-
(2009)
Science
, vol.324
, pp. 1035-1044
-
-
Tishkoff, S.A.1
Reed, F.A.2
Friedlaender, F.R.3
Ehret, C.4
Ranciaro, A.5
Froment, A.6
Hirbo, J.B.7
Awomoyi, A.A.8
Bodo, J.M.9
Doumbo, O.10
-
35
-
-
50549083074
-
Curses - Winner's and otherwise - In genetic epidemiology
-
Kraft, P. (2008) Curses - winner's and otherwise - in genetic epidemiology. Epidemiology, 19, 649-651.
-
(2008)
Epidemiology
, vol.19
, pp. 649-651
-
-
Kraft, P.1
-
36
-
-
77955646179
-
Association of trypanolytic ApoL1 variants with kidney disease in African Americans
-
Genovese, G., Friedman, D.J., Ross, M.D., Lecordier, L., Uzureau, P., Freedman, B.I., Bowden, D.W., Langefeld, C.D., Oleksyk, T.K., Uscinski Knob, A.L. et al. (2010) Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science, 329, 841-845.
-
(2010)
Science
, vol.329
, pp. 841-845
-
-
Genovese, G.1
Friedman, D.J.2
Ross, M.D.3
Lecordier, L.4
Uzureau, P.5
Freedman, B.I.6
Bowden, D.W.7
Langefeld, C.D.8
Oleksyk, T.K.9
Uscinski Knob, A.L.10
-
37
-
-
84959315811
-
Apolipoprotein L1 and kidney disease in African Americans
-
Friedman, D.J. and Pollak, M.R. (2016) Apolipoprotein L1 and kidney disease in African Americans. Trends Endocrinol. Metab., 27, 204-215.
-
(2016)
Trends Endocrinol. Metab.
, vol.27
, pp. 204-215
-
-
Friedman, D.J.1
Pollak, M.R.2
-
38
-
-
33646405178
-
Susceptible and protective eNOS haplotypes in hypertensive black and white subjects
-
Sandrim, V.C., Coelho, E.B., Nobre, F., Arado, G.M., Lanchote, V.L. and Tanus-Santos, J.E. (2006) Susceptible and protective eNOS haplotypes in hypertensive black and white subjects. Atherosclerosis, 186, 428-432.
-
(2006)
Atherosclerosis
, vol.186
, pp. 428-432
-
-
Sandrim, V.C.1
Coelho, E.B.2
Nobre, F.3
Arado, G.M.4
Lanchote, V.L.5
Tanus-Santos, J.E.6
-
39
-
-
84866611528
-
Pharmacogenomics knowledge for personalized medicine
-
Whirl-Carrillo, M., McDonagh, E.M., Hebert, J.M., Gong, L., Sangkuhl, K., Thorn, C.F., Altman, R.B. and Klein, T.E. (2012) Pharmacogenomics knowledge for personalized medicine. Clin. Pharmacol. Ther., 92, 414-417.
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, pp. 414-417
-
-
Whirl-Carrillo, M.1
McDonagh, E.M.2
Hebert, J.M.3
Gong, L.4
Sangkuhl, K.5
Thorn, C.F.6
Altman, R.B.7
Klein, T.E.8
-
40
-
-
84858999318
-
A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: Results from the Norfolk Arthritis Register
-
Plant, D., Farragher, T., Flynn, E.,Martin, P., Eyre, S., Bunn, D., Worthington, J., Symmons, D., Barton, A. and Thomson, W. (2012) A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: results from the Norfolk Arthritis Register. Pharmacogenomics J., 12, 128-133.
-
(2012)
Pharmacogenomics J.
, vol.12
, pp. 128-133
-
-
Plant, D.1
Farragher, T.2
Flynn, E.3
Martin, P.4
Eyre, S.5
Bunn, D.6
Worthington, J.7
Symmons, D.8
Barton, A.9
Thomson, W.10
-
41
-
-
84927177410
-
Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
-
Bank S., Andersen, P.S., Burisch, J., Pedersen, N., Roug, S., Galsgaard, J., Turino, S.Y., Brodersen, J.B., Rashid, S., Rasmussen, B.K. et al. (2014) Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. Pharmacogenomics J., 14, 526-534.
-
(2014)
Pharmacogenomics J.
, vol.14
, pp. 526-534
-
-
Bank, S.1
Andersen, P.S.2
Burisch, J.3
Pedersen, N.4
Roug, S.5
Galsgaard, J.6
Turino, S.Y.7
Brodersen, J.B.8
Rashid, S.9
Rasmussen, B.K.10
-
42
-
-
84971284049
-
A prospective pharmacogenomic study of Crohn's disease patients during routine therapy with anti-TNFalpha drug adalimumab: Contribution of ATG5, NFKB1, and CRP genes to pharmacodynamic variability
-
Dezelak, M., Repnik, K., Koder, S., Ferkolj, I. and Potočnik, U. (2016) A prospective pharmacogenomic study of Crohn's disease patients during routine therapy with anti-TNFalpha drug adalimumab: contribution of ATG5, NFKB1, and CRP genes to pharmacodynamic variability. OMICS, 20, 296-309.
-
(2016)
OMICS
, vol.20
, pp. 296-309
-
-
Dezelak, M.1
Repnik, K.2
Koder, S.3
Ferkolj, I.4
Potočnik, U.5
-
43
-
-
84937605375
-
Paradoxical psoriasiform reactions to anti-TNFalpha drugs are associated with genetic polymorphisms in patients with psoriasis
-
240
-
Cabaleiro, T., Prieto-Pérez, R., Navarro, R., Solano, G., Román, M., Ochoa, D., Abad-Santos, F. and Daudén, E. (2016) Paradoxical psoriasiform reactions to anti-TNFalpha drugs are associated with genetic polymorphisms in patients with psoriasis. Pharmacogenomics J., 16, 336-240.
-
(2016)
Pharmacogenomics J.
, vol.16
, pp. 336
-
-
Cabaleiro, T.1
Prieto-Pérez, R.2
Navarro, R.3
Solano, G.4
Román, M.5
Ochoa, D.6
Abad-Santos, F.7
Daudén, E.8
-
44
-
-
85010303854
-
Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 genes are associated with the response to TNF inhibitors in patients with rheumatoid arthritis
-
Conigliaro, P., Ciccacci, C., Politi, C., Triggianese, P., Rufini, S., Kroegler, B., Perricone, C., Latini, A., Novelli, G., Borgiani, P. et al. (2017) Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 genes are associated with the response to TNF inhibitors in patients with rheumatoid arthritis. PLoS One, 12, e0169956.
-
(2017)
PLoS One
, vol.12
-
-
Conigliaro, P.1
Ciccacci, C.2
Politi, C.3
Triggianese, P.4
Rufini, S.5
Kroegler, B.6
Perricone, C.7
Latini, A.8
Novelli, G.9
Borgiani, P.10
-
45
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter, D., MacArthur, J., Morales, J., Burdett, T., Hall, P., Junkins, H., Klemm, A., Flicek, P., Manolio, T., Hindorff, L. et al. (2014) The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res., 42(Database issue), D1001-D1006.
-
(2014)
Nucleic Acids Res.
, vol.42
, Issue.DATABASE ISSUE
, pp. D1001-D1006
-
-
Welter, D.1
MacArthur, J.2
Morales, J.3
Burdett, T.4
Hall, P.5
Junkins, H.6
Klemm, A.7
Flicek, P.8
Manolio, T.9
Hindorff, L.10
-
46
-
-
49449088389
-
Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility
-
Julià, A., Ballina, J., Cañete, J.D., Balsa, A., Tornero-Molina, J., Naranjo, A., Alperi-López, M., Erra, A., Pascual-Salcedo, D., Barceló, P. et al. (2008) Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility. Arthritis Rheum., 58, 2275-2286.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2275-2286
-
-
Julià, A.1
Ballina, J.2
Cañete, J.D.3
Balsa, A.4
Tornero-Molina, J.5
Naranjo, A.6
Alperi-López, M.7
Erra, A.8
Pascual-Salcedo, D.9
Barceló, P.10
-
47
-
-
84941733052
-
Interactive big data resource to elucidate human immune pathways and diseases
-
Gorenshteyn, D., Zaslavsky, E., Fribourg, M., Park, C.Y., Wong, A.K., Tadych, A., Hartmann, B.M., Albrecht, R.A., García-Sastre, A., Kleinstein, S.H. et al. (2015) Interactive big data resource to elucidate human immune pathways and diseases. Immunity, 43, 605-614.
-
(2015)
Immunity
, vol.43
, pp. 605-614
-
-
Gorenshteyn, D.1
Zaslavsky, E.2
Fribourg, M.3
Park, C.Y.4
Wong, A.K.5
Tadych, A.6
Hartmann, B.M.7
Albrecht, R.A.8
García-Sastre, A.9
Kleinstein, S.H.10
-
48
-
-
84873193482
-
Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3- CD4+ CD25- T cells modulates TLR-4 induced TNF-alpha production
-
Boswell, S., Pathan, A.A., Pereira, S.P., Williams, R. and Behboudi, S. (2013) Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3- CD4+ CD25- T cells modulates TLR-4 induced TNF-alpha production. Immunobiology, 218, 427-434.
-
(2013)
Immunobiology
, vol.218
, pp. 427-434
-
-
Boswell, S.1
Pathan, A.A.2
Pereira, S.P.3
Williams, R.4
Behboudi, S.5
-
49
-
-
84966605759
-
GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/beta-catenin signaling in lung adenocarcinoma
-
Yuan, S., Yu, Z., Liu, Q., Zhang, M., Xiang, Y., Wu, N., Wu, L., Hu, Z., Xu, B., Cai, T. et al. (2016) GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/beta-catenin signaling in lung adenocarcinoma. Oncogene, 35, 6120-6131.
-
(2016)
Oncogene
, vol.35
, pp. 6120-6131
-
-
Yuan, S.1
Yu, Z.2
Liu, Q.3
Zhang, M.4
Xiang, Y.5
Wu, N.6
Wu, L.7
Hu, Z.8
Xu, B.9
Cai, T.10
-
50
-
-
77956395532
-
Association to the Glypican-5 gene in multiple sclerosis
-
Lorentzen, A.R., Melum, E., Ellinghaus, E., Smestad, C., Mero, I.L., Aarseth, J.H., Myhr, K.M., Celius, E.G., Lie, B.A., Karlsen, T.H. et al. (2010) Association to the Glypican-5 gene in multiple sclerosis. J. Neuroimmunol., 226, 194-197.
-
(2010)
J. Neuroimmunol.
, vol.226
, pp. 194-197
-
-
Lorentzen, A.R.1
Melum, E.2
Ellinghaus, E.3
Smestad, C.4
Mero, I.L.5
Aarseth, J.H.6
Myhr, K.M.7
Celius, E.G.8
Lie, B.A.9
Karlsen, T.H.10
-
51
-
-
79952282726
-
Replication of top markers of a genome-wide association study in multiple sclerosis in Spain
-
Cavanillas, M.L., Fernández, O., Comabella, M., Alcina, A., Fedetz, M., Izquierdo, G., Lucas, M., Cénit, M.C., Arroyo, R., Vandenbroeck, K. et al. (2011) Replication of top markers of a genome-wide association study in multiple sclerosis in Spain. Genes Immun., 12, 110-115.
-
(2011)
Genes Immun.
, vol.12
, pp. 110-115
-
-
Cavanillas, M.L.1
Fernández, O.2
Comabella, M.3
Alcina, A.4
Fedetz, M.5
Izquierdo, G.6
Lucas, M.7
Cénit, M.C.8
Arroyo, R.9
Vandenbroeck, K.10
-
52
-
-
77953123336
-
Multiple sclerosis susceptibility alleles in African Americans
-
Johnson, B.A., Wang, J., Taylor, E.M., Caillier, S.J., Herbert, J., Khan, O.A., Cross, A.H., De Jager, P.L., Gourraud, P.A., Cree, B.C. et al. (2010) Multiple sclerosis susceptibility alleles in African Americans. Genes Immun., 11, 343-350.
-
(2010)
Genes Immun.
, vol.11
, pp. 343-350
-
-
Johnson, B.A.1
Wang, J.2
Taylor, E.M.3
Caillier, S.J.4
Herbert, J.5
Khan, O.A.6
Cross, A.H.7
De Jager, P.L.8
Gourraud, P.A.9
Cree, B.C.10
-
53
-
-
69549135691
-
Glypican 5 is an interferon-beta response gene: A replication study
-
Cenit, M.D., Blanco-Kelly, F., de las Heras, V., Bartolomé, M., de la Concha, E.G., Urcelay, E., Arroyo, R. and Martínez, A. (2009) Glypican 5 is an interferon-beta response gene: a replication study. Mult. Scler., 15, 913-917.
-
(2009)
Mult. Scler.
, vol.15
, pp. 913-917
-
-
Cenit, M.D.1
Blanco-Kelly, F.2
De Las Heras, V.3
Bartolomé, M.4
De La Concha, E.G.5
Urcelay, E.6
Arroyo, R.7
Martínez, A.8
-
54
-
-
84903548291
-
Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis
-
Aterido, A., Palacio,C., Marsal, S.,Avila,G. and Julià,A. (2014) Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis. PLoS One, 9, e100690.
-
(2014)
PLoS One
, vol.9
-
-
Aterido, A.1
Palacio, C.2
Marsal, S.3
Avila, G.4
Julià, A.5
-
55
-
-
85014061753
-
Connecting genetic risk to disease end points through the human blood plasma proteome
-
Suhre, K.,Arnold, M., Bhagwat,A.M., Cotton, R.J., Engelke, R., Raffler, J., Sarwath, H., Thareja, G., Wahl, A., DeLisle, R.K. et al. (2017) Connecting genetic risk to disease end points through the human blood plasma proteome. Nat. Commun., 8, 14357.
-
(2017)
Nat. Commun.
, vol.8
, pp. 14357
-
-
Suhre, K.1
Arnold, M.2
Bhagwat, A.M.3
Cotton, R.J.4
Engelke, R.5
Raffler, J.6
Sarwath, H.7
Thareja, G.8
Wahl, A.9
DeLisle, R.K.10
-
56
-
-
85013957711
-
Immunopathogenesis of rheumatoid arthritis
-
Firestein, G., and McInnes, I.B. (2017) Immunopathogenesis of rheumatoid arthritis. Immunity, 46, 183-196.
-
(2017)
Immunity
, vol.46
, pp. 183-196
-
-
Firestein, G.1
McInnes, I.B.2
-
57
-
-
84860390022
-
Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: Novel insights into autoantigen selection in rheumatoid arthritis
-
Darrah, E., Rosen, A., Giles, J.T. and Andrade, F. (2012) Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis. Ann. Rheum. Dis., 71, 92-98.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 92-98
-
-
Darrah, E.1
Rosen, A.2
Giles, J.T.3
Andrade, F.4
-
58
-
-
84936791693
-
Genomic modulators of gene expression in human neutrophils
-
Naranbhai, V., Fairfax, B.P., Makino, S., Humburg, P., Wong, D., Ng, E., Hill, A.V. and Knight, J.C. (2015) Genomic modulators of gene expression in human neutrophils. Nat. Commun., 6, 7545.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7545
-
-
Naranbhai, V.1
Fairfax, B.P.2
Makino, S.3
Humburg, P.4
Wong, D.5
Ng, E.6
Hill, A.V.7
Knight, J.C.8
-
59
-
-
84965081767
-
Increased levels of peptidylarginine deiminase 2 in synovial f luid fromanti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers
-
Damgaard, D., Senolt, L. and Nielsen, C.H. (2016) Increased levels of peptidylarginine deiminase 2 in synovial f luid fromanti-CCP-positive rheumatoid arthritis patients: association with disease activity and inflammatory markers. Rheumatology (Oxford), 55, 918-927.
-
(2016)
Rheumatology (Oxford)
, vol.55
, pp. 918-927
-
-
Damgaard, D.1
Senolt, L.2
Nielsen, C.H.3
-
60
-
-
85011615063
-
Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation
-
Bawadekar, M., Shim, D., Johnson, C.J., Warner, T.F., Rebernick, R., Damgaard, D., Nielsen, C.H., Pruijn, G.J.M., Nett, J.E. and Shelef, M.A. (2017) Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation. J. Autoimmun., 80, 39-47.
-
(2017)
J. Autoimmun.
, vol.80
, pp. 39-47
-
-
Bawadekar, M.1
Shim, D.2
Johnson, C.J.3
Warner, T.F.4
Rebernick, R.5
Damgaard, D.6
Nielsen, C.H.7
Pruijn, G.J.M.8
Nett, J.E.9
Shelef, M.A.10
-
61
-
-
84860333083
-
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
-
Stahl, E.A., Wegmann, D., Trynka, G., Gutierrez-Achury, J., Do, R., Voight, B.F., Kraft, P., Chen, R., Kallberg, H.J., Kurreeman, F.A. et al. (2012) Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat. Genet., 44, 483-489.
-
(2012)
Nat. Genet.
, vol.44
, pp. 483-489
-
-
Stahl, E.A.1
Wegmann, D.2
Trynka, G.3
Gutierrez-Achury, J.4
Do, R.5
Voight, B.F.6
Kraft, P.7
Chen, R.8
Kallberg, H.J.9
Kurreeman, F.A.10
-
62
-
-
84962498653
-
Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
-
Cavalli, M., Pan, G., Nord, H.,Wallerman, O.,Wallén Arzt, E., Berggren,O.,Elvers, I.,Eloranta,M.L.,Rönnblom,L., Lindblad Toh, K. et al. (2016) Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression. Hum. Genet., 135, 485-497.
-
(2016)
Hum. Genet.
, vol.135
, pp. 485-497
-
-
Cavalli, M.1
Pan, G.2
Nord, H.3
Wallerman, O.4
Wallén Arzt, E.5
Berggren, O.6
Elvers, I.7
Eloranta, M.L.8
Rönnblom, L.9
Lindblad Toh, K.10
-
63
-
-
84865852567
-
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
-
Wang, J., Zhuang, J., Iyer, S., Lin, X.,Whitfield, T.W., Greven, M.C., Pierce, B.G., Dong, X., Kundaje, A., Cheng, Y. et al. (2012) Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res., 22, 1798-1812.
-
(2012)
Genome Res.
, vol.22
, pp. 1798-1812
-
-
Wang, J.1
Zhuang, J.2
Iyer, S.3
Lin, X.4
Whitfield, T.W.5
Greven, M.C.6
Pierce, B.G.7
Dong, X.8
Kundaje, A.9
Cheng, Y.10
-
64
-
-
84866893076
-
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese
-
Myouzen, K., Kochi, Y., Okada, Y., Terao, C., Suzuki, A., Ikari, K., Tsunoda, T., Takahashi, A., Kubo, M., Taniguchi, A. et al. (2012) Functional variants in NFKBIE and RTKN2 involved in activation of the NF-kappaB pathway are associated with rheumatoid arthritis in Japanese. PLoS Genet., 8, e1002949-e1002962.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002949-e1002962
-
-
Myouzen, K.1
Kochi, Y.2
Okada, Y.3
Terao, C.4
Suzuki, A.5
Ikari, K.6
Tsunoda, T.7
Takahashi, A.8
Kubo, M.9
Taniguchi, A.10
-
65
-
-
84952768681
-
Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line
-
Imamura, H., Yoshina, S., Ikari, K., Miyazawa, K., Momohara, S. and Mitani, S. (2016) Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line. Mod. Rheumatol., 26, 507-516.
-
(2016)
Mod. Rheumatol.
, vol.26
, pp. 507-516
-
-
Imamura, H.1
Yoshina, S.2
Ikari, K.3
Miyazawa, K.4
Momohara, S.5
Mitani, S.6
-
66
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda, H., Howson, J.M., Esposito, L., Heward, J., Snook, H., Chamberlain,G., Rainbow,D.B.,Hunter, K.M., Smith,A.N., Di Genova, G. et al. (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature, 423, 506-511.
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
Heward, J.4
Snook, H.5
Chamberlain, G.6
Rainbow, D.B.7
Hunter, K.M.8
Smith, A.N.9
Di Genova, G.10
-
67
-
-
85053470626
-
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
-
Westra, H.J., Martínez-Bonet, M., Onengut-Gumuscu, S., Lee, A., Luo, Y., Teslovich, N., Worthington, J., Martin, J., Huizinga, T., Klareskog, L. et al. (2018) Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nat. Genet., 50, 1366-1374.
-
(2018)
Nat. Genet.
, vol.50
, pp. 1366-1374
-
-
Westra, H.J.1
Martínez-Bonet, M.2
Onengut-Gumuscu, S.3
Lee, A.4
Luo, Y.5
Teslovich, N.6
Worthington, J.7
Martin, J.8
Huizinga, T.9
Klareskog, L.10
-
68
-
-
84955332058
-
Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes
-
de Jong, V.M., Zaldumbide, A., van der Slik, A.R., Laban, S., Koeleman, B.P. and Roep, B.O. (2016) Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes. Genes Immun., 17, 75-78.
-
(2016)
Genes Immun.
, vol.17
, pp. 75-78
-
-
De Jong, V.M.1
Zaldumbide, A.2
Van Der Slik, A.R.3
Laban, S.4
Koeleman, B.P.5
Roep, B.O.6
-
69
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and co-inhibition
-
Chen, L. and Flies, D.B. (2013) Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol., 13, 227-242.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
70
-
-
85045436990
-
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity
-
Harley, J.B., Chen, X., Pujato, M., Miller, D., Maddox, A., Forney, C., Magnusen, A.F., Lynch, A., Chetal, K., Yukawa, M. et al. (2018) Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. Nat. Genet., 50, 699-707.
-
(2018)
Nat. Genet.
, vol.50
, pp. 699-707
-
-
Harley, J.B.1
Chen, X.2
Pujato, M.3
Miller, D.4
Maddox, A.5
Forney, C.6
Magnusen, A.F.7
Lynch, A.8
Chetal, K.9
Yukawa, M.10
-
71
-
-
84984788469
-
EBV nuclear antigen 3Cmediates regulation of E2F6 to inhibit E2F1 transcription and promote cell proliferation
-
Pei, Y. (2016) EBV nuclear antigen 3Cmediates regulation of E2F6 to inhibit E2F1 transcription and promote cell proliferation. PLoS Pathog., 12, e1005844-e1005868.
-
(2016)
PLoS Pathog.
, vol.12
, pp. e1005844-e1005868
-
-
Pei, Y.1
-
72
-
-
84928641788
-
Expression of interferon-γ receptor genes in PBMCs is associated with rheumatoid arthritis and its radiographic severity in African Americans
-
Tang, Q., Danila, M.I., Cui, X., Parks, L., Baker, B.J., Reynolds, R.J., Raman, C., Wanseck, K.C., Redden, D.T., Johnson, M.R. et al. (2015) Expression of interferon-γ receptor genes in PBMCs is associated with rheumatoid arthritis and its radiographic severity in African Americans. Arthritis Rheumatol., 67, 1165-1170.
-
(2015)
Arthritis Rheumatol.
, vol.67
, pp. 1165-1170
-
-
Tang, Q.1
Danila, M.I.2
Cui, X.3
Parks, L.4
Baker, B.J.5
Reynolds, R.J.6
Raman, C.7
Wanseck, K.C.8
Redden, D.T.9
Johnson, M.R.10
-
73
-
-
32344453016
-
IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes
-
Regis, G., Conti, L., Boselli, D. and Novelli, F. (2006) IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes. Trends Immunol., 27, 96-101.
-
(2006)
Trends Immunol.
, vol.27
, pp. 96-101
-
-
Regis, G.1
Conti, L.2
Boselli, D.3
Novelli, F.4
-
74
-
-
0030889207
-
The IFN gamma receptor: A paradigm for cytokine receptor signaling
-
Bach, E.A., Aguet, M. and Schreiber, R.D. (1997) The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol., 15, 563-591.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 563-591
-
-
Bach, E.A.1
Aguet, M.2
Schreiber, R.D.3
-
75
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett, F.C., Edworthy, S.M., Bloch, D.A., McShane, D.J., Fries, J.F., Cooper, N.S., Healey, L.A., Kaplan, S.R., Liang, M.H., Luthra, H.S. et al. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum., 31, 315-324.
-
(1988)
Arthritis Rheum.
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
Healey, L.A.7
Kaplan, S.R.8
Liang, M.H.9
Luthra, H.S.10
-
76
-
-
0029081958
-
A connective tissue disease screening questionnaire for population studies
-
Karlson, E.W., Sanchez-Guerrero, J., Wright, E.A., Lew, R.A., Daltroy, L.H., Katz, J.N. and Liang, M.H. (1995) A connective tissue disease screening questionnaire for population studies. Ann. Epidemiol., 5, 297-302.
-
(1995)
Ann. Epidemiol.
, vol.5
, pp. 297-302
-
-
Karlson, E.W.1
Sanchez-Guerrero, J.2
Wright, E.A.3
Lew, R.A.4
Daltroy, L.H.5
Katz, J.N.6
Liang, M.H.7
-
77
-
-
27744501026
-
High sensitivity, specificity and predictive value of the connective tissue disease screening questionnaire among urban African-American women
-
Karlson, E.W., Costenbader, K.H., McAlindon, T.E., Massarotti, E.M., Fitzgerald, L.M., Jajoo, R., Husni, E., Wright, E.A., Pankey, H. and Fraser, P.A. (2005) High sensitivity, specificity and predictive value of the connective tissue disease screening questionnaire among urban African-American women. Lupus, 14, 832-836.
-
(2005)
Lupus
, vol.14
, pp. 832-836
-
-
Karlson, E.W.1
Costenbader, K.H.2
McAlindon, T.E.3
Massarotti, E.M.4
Fitzgerald, L.M.5
Jajoo, R.6
Husni, E.7
Wright, E.A.8
Pankey, H.9
Fraser, P.A.10
-
78
-
-
77957682072
-
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis
-
Tan, W., Wu, H., Zhao, J., Derber, L.A., Lee, D.M., Shadick, N.A., Conn,D.L., Smith, E.A., Gersuk, V.H.,Nepom, G.T. et al. (2010) A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis. Arthritis Rheum., 62, 2864-2875.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2864-2875
-
-
Tan, W.1
Wu, H.2
Zhao, J.3
Derber, L.A.4
Lee, D.M.5
Shadick, N.A.6
Conn, D.L.7
Smith, E.A.8
Gersuk, V.H.9
Nepom, G.T.10
-
79
-
-
80052377390
-
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis
-
Song, J.J.,Hwang, I., Cho, K.H., Garcia, M.A., Kim,A.J., Wang, T.H., Lindstrom, T.M., Lee, A.T., Nishimura, T., Zhao, L. et al. (2011) Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis. J. Clin. Invest., 121, 3517-3527.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3517-3527
-
-
Song, J.J.1
Hwang, I.2
Cho, K.H.3
Garcia, M.A.4
Kim, A.J.5
Wang, T.H.6
Lindstrom, T.M.7
Lee, A.T.8
Nishimura, T.9
Zhao, L.10
-
80
-
-
77951718514
-
Radiographic severity of rheumatoid arthritis in African Americans: Results from a multicenter observational study
-
Bridges, S.L., Jr, Causey, Z.L., Burgos, P.I., Huynh, B.Q., Hughes, L.B., Danila, M.I., van Everdingen, A., Ledbetter, S., Conn, D.L., Tamhane, A. et al. (2010) Radiographic severity of rheumatoid arthritis in African Americans: results from a multicenter observational study. Arthritis Care Res. (Hoboken), 62, 624-631.
-
(2010)
Arthritis Care Res. (Hoboken)
, vol.62
, pp. 624-631
-
-
Bridges, S.L.1
Causey, Z.L.2
Burgos, P.I.3
Huynh, B.Q.4
Hughes, L.B.5
Danila, M.I.6
Van Everdingen, A.7
Ledbetter, S.8
Conn, D.L.9
Tamhane, A.10
-
81
-
-
33749332346
-
Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis
-
Mikuls, T.R., Holers, V.M., Parrish, L., Kuhn, K.A., Conn, D.L., Gilkeson, G., Smith, E.A., Kamen, D.L., Jonas, B.L., Callahan, L.F. et al. (2006) Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis. Arthritis Rheum., 54, 3057-3059.
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 3057-3059
-
-
Mikuls, T.R.1
Holers, V.M.2
Parrish, L.3
Kuhn, K.A.4
Conn, D.L.5
Gilkeson, G.6
Smith, E.A.7
Kamen, D.L.8
Jonas, B.L.9
Callahan, L.F.10
-
82
-
-
84988908932
-
Insights and implications of the VA Rheumatoid Arthritis Registry
-
Mikuls, T.R., Kerr,G.S., and Cannon,G.W. (2015) Insights and implications of the VA Rheumatoid Arthritis Registry. Fed. Pract, 32, 24-29.
-
(2015)
Fed. Pract
, vol.32
, pp. 24-29
-
-
Mikuls, T.R.1
Kerr, G.S.2
Cannon, G.W.3
-
83
-
-
34447503679
-
The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis
-
Mikuls, T.R., Kazi, S., Cipher, D., Hooker, R., Kerr, G.S., Richards, J.S. and Cannon, G.W. (2007) The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis. J. Rheumatol., 34, 1480-1484.
-
(2007)
J. Rheumatol.
, vol.34
, pp. 1480-1484
-
-
Mikuls, T.R.1
Kazi, S.2
Cipher, D.3
Hooker, R.4
Kerr, G.S.5
Richards, J.S.6
Cannon, G.W.7
-
84
-
-
84892641078
-
Allelic-dependent expression of an activating Fc receptor on B cells enhances humoral immune responses
-
Li, X., Wu, J., Ptacek, T., Redden, D.T., Brown, E.E., Alarcón, G.S., Ramsey-Goldman, R., Petri, M.A., Reveille, J.D., Kaslow, R.A. et al. (2013) Allelic-dependent expression of an activating Fc receptor on B cells enhances humoral immune responses. Sci. Transl. Med., 5, 216ra175-216ra186.
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 216ra175-216ra186
-
-
Li, X.1
Wu, J.2
Ptacek, T.3
Redden, D.T.4
Brown, E.E.5
Alarcón, G.S.6
Ramsey-Goldman, R.7
Petri, M.A.8
Reveille, J.D.9
Kaslow, R.A.10
-
85
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price, A.L., Patterson, N.J., Plenge, R.M., Weinblatt, M.E., Shadick, N.A. and Reich, D. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet., 38, 904-909.
-
(2006)
Nat. Genet.
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
86
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B.N., Donnelly, P. and Marchini, J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
-
(2009)
PLoS Genet.
, vol.5
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
87
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet., 39, 906-913.
-
(2007)
Nat. Genet.
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
88
-
-
42249087793
-
Estimation of significance thresholds for genomewide association scans
-
Dudbridge, F. and Gusnanto, A. (2008) Estimation of significance thresholds for genomewide association scans. Genet. Epidemiol., 32, 227-234.
-
(2008)
Genet. Epidemiol.
, vol.32
, pp. 227-234
-
-
Dudbridge, F.1
Gusnanto, A.2
-
89
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch, N. and Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science, 273, 1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
90
-
-
85006307101
-
A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy
-
Wang, Z., Sun, Y., Fu, X., Yu, G., Wang, C., Bao, F., Yue, Z., Li, J., Sun, L., Irwanto, A. et al. (2016) A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy. Nat. Commun., 7, 13760-13767.
-
(2016)
Nat. Commun.
, vol.7
, pp. 13760-13767
-
-
Wang, Z.1
Sun, Y.2
Fu, X.3
Yu, G.4
Wang, C.5
Bao, F.6
Yue, Z.7
Li, J.8
Sun, L.9
Irwanto, A.10
-
91
-
-
31744435871
-
Joint analysis ismore efficient than replication-based analysis for two-stage genome-wide association studies
-
Skol, A.D., Scott, L.J., Abecasis, G.R. and Boehnke, M. (2006) Joint analysis ismore efficient than replication-based analysis for two-stage genome-wide association studies. Nat. Genet., 38, 209-213.
-
(2006)
Nat. Genet.
, vol.38
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
Boehnke, M.4
-
92
-
-
26444433586
-
Bayesian statistical inference for psychological research
-
Edwards, W., Lindman, H. and Savage, L.J. (1963) Bayesian statistical inference for psychological research. Psychol. Rev., 70, 193-242.
-
(1963)
Psychol. Rev.
, vol.70
, pp. 193-242
-
-
Edwards, W.1
Lindman, H.2
Savage, L.J.3
-
93
-
-
80052376347
-
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
-
Menard, L., Saadoun, D., Isnardi, I., Ng, Y.S., Meyers, G., Massad, C., Price, C., Abraham, C., Motaghedi, R., Buckner, J.H. et al. (2011) The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. J. Clin. Invest., 121, 3635-3644.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3635-3644
-
-
Menard, L.1
Saadoun, D.2
Isnardi, I.3
Ng, Y.S.4
Meyers, G.5
Massad, C.6
Price, C.7
Abraham, C.8
Motaghedi, R.9
Buckner, J.H.10
-
94
-
-
84975153627
-
Novel insights into the multiple sclerosis risk gene ANKRD55
-
Lopez de Lapuente, A., Feliú, A., Ugidos, N., Mecha, M., Mena, J., Astobiza, I., Riera, J., Carrillo-Salinas, F.J., Comabella,M., Montalban, X. et al. (2016) Novel insights into the multiple sclerosis risk gene ANKRD55. J. Immunol., 196, 4553-4565.
-
(2016)
J. Immunol.
, vol.196
, pp. 4553-4565
-
-
Lopez De Lapuente, A.1
Feliú, A.2
Ugidos, N.3
Mecha, M.4
Mena, J.5
Astobiza, I.6
Riera, J.7
Carrillo-Salinas, F.J.8
Comabella, M.9
Montalban, X.10
-
95
-
-
79952158486
-
Tyrosine kinase 2 variant influences T lymphocyte polarization andmultiple sclerosis susceptibility
-
Couturier, N., Bucciarelli, F., Nurtdinov, R.N., Debouverie, M., Lebrun-Frenay, C., Defer, G., Moreau, T., Confavreux, C., Vukusic, S., Cournu-Rebeix, I. et al. (2011) Tyrosine kinase 2 variant influences T lymphocyte polarization andmultiple sclerosis susceptibility. Brain, 134(Pt 3), 693-703.
-
(2011)
Brain
, vol.134
, pp. 693-703
-
-
Couturier, N.1
Bucciarelli, F.2
Nurtdinov, R.N.3
Debouverie, M.4
Lebrun-Frenay, C.5
Defer, G.6
Moreau, T.7
Confavreux, C.8
Vukusic, S.9
Cournu-Rebeix, I.10
-
96
-
-
85018726619
-
Conditional eQTL analysis reveals allelic heterogeneity of gene expression
-
Jansen, R., Hottenga, J.J., Nivard, M.G., Abdellaoui, A., Laport, B., de Geus, E.J., Wright, F.A., Penninx, B.W.J.H. and Boomsma, D.I. (2017) Conditional eQTL analysis reveals allelic heterogeneity of gene expression. Hum. Mol. Genet., 26, 1444-1451.
-
(2017)
Hum. Mol. Genet.
, vol.26
, pp. 1444-1451
-
-
Jansen, R.1
Hottenga, J.J.2
Nivard, M.G.3
Abdellaoui, A.4
Laport, B.5
De Geus, E.J.6
Wright, F.A.7
Penninx, B.W.J.H.8
Boomsma, D.I.9
-
97
-
-
84891697734
-
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
-
Corradin, O., Saiakhova, A., Akhtar-Zaidi, B., Myeroff, L., Willis, J., Cowper-Sal lari, R., Lupien, M. and Markowitz, S. (2014) Scacheri PC. Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Res., 24, 1-13.
-
(2014)
Genome Res.
, vol.24
, pp. 1-13
-
-
Corradin, O.1
Saiakhova, A.2
Akhtar-Zaidi, B.3
Myeroff, L.4
Willis, J.5
Cowper-Sal Lari, R.6
Lupien, M.7
Markowitz, S.8
Scacheri, P.C.9
-
98
-
-
77955425717
-
Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios
-
Bokor, S., Dumont, J., Spinneker, A., Gonzalez-Gross, M., Nova, E.,Widhalm, K.,Moschonis, G., Stehle, P., Amouyel, P., De Henauw, S. et al. (2010) Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J. Lipid Res., 51, 2325-2333.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 2325-2333
-
-
Bokor, S.1
Dumont, J.2
Spinneker, A.3
Gonzalez-Gross, M.4
Nova, E.5
Widhalm, K.6
Moschonis, G.7
Stehle, P.8
Amouyel, P.9
De Henauw, S.10
-
99
-
-
85008932613
-
Rs657075 (CSF2) is associated with the disease phenotype (BAS-G) of ankylosing spondylitis
-
Chen, W.C., Wei, J.C., Lu, H.F., Wong, H.S., Woon, P.Y., Hsu, Y.W., Huang, J.D. and Chang, W.C. (2017) rs657075 (CSF2) is associated with the disease phenotype (BAS-G) of ankylosing spondylitis. Int. J. Mol. Sci., 18, E83-E95.
-
(2017)
Int. J. Mol. Sci.
, vol.18
, pp. E83-E95
-
-
Chen, W.C.1
Wei, J.C.2
Lu, H.F.3
Wong, H.S.4
Woon, P.Y.5
Hsu, Y.W.6
Huang, J.D.7
Chang, W.C.8
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