Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese

PLoS Genetics

Volumn 8, Issue 9, 2012, Pages

  Myouzen, Keiko ^a   Kochi, Yuta ^a,b   Okada, Yukinori ^a,b   Terao, Chikashi ^c,d   Suzuki, Akari ^a   Ikari, Katsunori ^e   Tsunoda, Tatsuhiko ^a   Takahashi, Atsushi ^a   Kubo, Michiaki ^a   Taniguchi, Atsuo ^e   Matsuda, Fumihiko ^c,f   Ohmura, Koichiro ^d   Momohara, Shigeki ^e   Mimori, Tsuneyo ^d   Yamanaka, Hisashi ^e   Kamatani, Naoyuki ^a   Yamada, Ryo ^d   Nakamura, Yusuke ^g   Yamamoto, Kazuhiko ^a,b  

^a RIKEN   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^g UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; GENE FUNCTION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC REGULATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; JAPANESE; MAJOR CLINICAL STUDY; NFKBIE GENE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POPULATION BASED CASE CONTROL STUDY; PROTEIN TARGETING; REPLICATION STUDY; RHEUMATOID ARTHRITIS; RTKN2 GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ARTHRITIS, RHEUMATOID; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; I-KAPPA B PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JAPAN; NF-KAPPA B; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION;

EID: 84866893076     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002949     Document Type: Article

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