Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation

Journal of Autoimmunity

Volumn 80, Issue , 2017, Pages 39-47

  Bawadekar, Mandar ^a   Shim, Daeun ^a   Johnson, Chad J ^a   Warner, Thomas F ^a   Rebernick, Ryan ^a   Damgaard, Dres ^b   Nielsen, Claus H ^b   Pruijn, Ger J M ^c   Nett, Jeniel E ^a,d   Shelef, Miriam A ^a,e  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Rigshospitalet   (Denmark)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

Author keywords

Citrullination; Murine model; Neutrophil extracellular trap; Peptidylarginine deiminase; Rheumatoid arthritis; TNF

Indexed keywords

IMMUNOGLOBULIN G; PEPTIDYLARGININE DEIMINASE 2; PEPTIDYLARGININE DEIMINASE 4; PROTEIN ARGININE DEIMINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; HYDROLASE; PEPTIDYLARGININE DEIMINASE 4, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKLE ARTHRITIS; ARTICLE; CANDIDA ALBICANS; CELL COUNT; CITRULLINATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL ARTHRITIS; EXTRACELLULAR TRAP; FEMALE; FLOW CYTOMETRY; FUNGAL VIABILITY; GENE OVEREXPRESSION; GRIP STRENGTH; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOUSE; NETOSIS; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN PROCESSING; RHEUMATOID ARTHRITIS; UPREGULATION; WESTERN BLOTTING; ANIMAL; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; JOINT; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ANTI-CITRULLINATED PROTEIN ANTIBODIES; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CITRULLINATION; EXTRACELLULAR TRAPS; HUMANS; HYDROLASES; IMMUNOGLOBULIN G; INFLAMMATION; JOINTS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PLASMA CELLS; PROTEIN-ARGININE DEIMINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85011615063     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2017.01.006     Document Type: Article

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