Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 199, Issue 12, 2019, Pages 1517-1536

  Reyfman, Paul A ^a   Walter, James M ^a   Joshi, Nikita ^a   Anekalla, Kishore R ^a   McQuattie Pimentel, Alexandra C ^a   Chiu, Stephen ^b   Fernandez, Ramiro ^b   Akbarpour, Mahzad ^b   Chen, Ching I ^d   Ren, Ziyou ^a   Verma, Rohan ^a   Abdala Valencia, Hiam ^a   Nam, Kiwon ^a   Chi, Monica ^a   Han, SeungHye ^a   Gonzalez Gonzalez, Francisco J ^a   Soberanes, Saul ^a   Watanabe, Satoshi ^a   Williams, Kinola J N ^a   Flozak, Annette S ^a   Nicholson, Trevor T ^a   Morgan, Vince K ^c   Winter, Deborah R ^c   Hinchcliff, Monique ^c   Hrusch, Cara L ^f   Guzy, Robert D ^f   Bonham, Catherine A ^f   Sperling, Anne I ^f   Bag, Remzi ^f   Hamanaka, Robert B ^f   Mutlu, Gökhan M ^f   Yeldandi, Anjana V ^d   Marshall, Stacy A ^e   Shilatifard, Ali ^e   Amaral, Luis A N ^g   Perlman, Harris ^c   Sznajder, Jacob I ^a   Christine Argento, A ^a,b   Gillespie, Colin T ^a,b   Dematte, Jane ^a   Jain, Manu ^a   Singer, Benjamin D ^a,e   Ridge, Karen M ^a   Lam, Anna P ^a   Bharat, Ankit ^b   Bhorade, Sangeeta M ^a   Gottardi, Cara J ^a   Scott Budinger, G R ^a   Misharin, Alexander V ^a,e   more..

^a Pulmonary and Critical Care Medicine   (United States)

^b Div of Cardiac Electrophysiology   (United States)

^c Division of Rheumatology   (United States)

^d Northwestern University ^*

^e NORTHWESTERN UNIVERSITY   (United States)

^f UNIVERSITY OF CHICAGO   (United States)

^g Northwestern University   (United States)

Author keywords

Alveolar macrophages; Alveolar type II cells; Pulmonary fibrosis; RNA sequencing

Indexed keywords

RNA; WNT PROTEIN; TRANSCRIPTOME;

ADULT; AGED; ARTICLE; BRONCHOSCOPY; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FIBROBLAST; FLOW CYTOMETRY; GENE EXPRESSION; GRAFT RECIPIENT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU RNA HYBRIDIZATION; LUNG ALVEOLUS MACROPHAGE; LUNG BIOPSY; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; MIDDLE AGED; NEXT GENERATION SEQUENCING; ORGAN DONOR; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SECRETION; RNA HYBRIDIZATION; RNA SEQUENCE; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; TRANSCRIPTOMICS; ANIMAL; CELL CULTURE; DISEASE MODEL; FIBROSING ALVEOLITIS; GENETICS; PATHOLOGY; SEQUENCE ANALYSIS; STEM CELL;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; SEQUENCE ANALYSIS, RNA; STEM CELLS; TRANSCRIPTOME;

EID: 85063607222     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201712-2410OC     Document Type: Article

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