Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung

Cell

Volumn 170, Issue 6, 2017, Pages 1134-1148.e10

  Zepp, Jarod A ^a,c   Zacharias, William J ^a,c   Frank, David B ^a,c   Cavanaugh, Christina A ^a,c   Zhou, Su ^c   Morley, Michael P ^a,c   Morrisey, Edward E ^a,b,c  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Fgf; lung; mesenchyme; organoid; regeneration; Wnt

Indexed keywords

FIBROBLAST GROWTH FACTOR; INTERLEUKIN 6; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINEAGE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FLOW CYTOMETRY; HOMEOSTASIS; LUNG ALVEOLUS CELL; LUNG INJURY; MESENCHYMAL STEM CELL; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELL SELF-RENEWAL; TISSUE REGENERATION; ALGORITHM; ANIMAL; CYTOLOGY; CYTOPLASM; FIBROSIS; GENE EXPRESSION PROFILING; LUNG; MESODERM; METABOLISM; PARACRINE SIGNALING; PATHOLOGY; PHYSIOLOGY; REGENERATION; SINGLE CELL ANALYSIS; STEM CELL;

ALGORITHMS; ANIMALS; EPITHELIAL CELLS; FIBROSIS; GENE EXPRESSION PROFILING; LUNG; LUNG INJURY; MESODERM; MICE; ORGANOIDS; PARACRINE COMMUNICATION; REGENERATION; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; STEM CELLS;

EID: 85028931659     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.07.034     Document Type: Article

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