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Volumn 356, Issue 6335, 2017, Pages

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(24)  Villani, Alexandra Chloé a,b   Satija, Rahul a,c   Reynolds, Gary d   Sarkizova, Siranush a   Shekhar, Karthik a   Fletcher, James d   Griesbeck, Morgane e   Butler, Andrew c   Zheng, Shiwei c   Lazo, Suzan f   Jardine, Laura d   Dixon, David d   Stephenson, Emily d   Nilsson, Emil g   Grundberg, Ida g   McDonald, David d   Filby, Andrew d   Li, Weibo a,b   De Jager, Philip L a,h   Rozenblatt Rosen, Orit a   more..


Author keywords

[No Author keywords available]

Indexed keywords

AXL ANTIGEN; CD100 ANTIGEN; CD14 ANTIGEN; CD163 ANTIGEN; CD1C ANTIGEN; CD34 ANTIGEN; CD36 ANTIGEN; HLA DR ANTIGEN; LYMPHOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SIALOADHESIN; SIGLEC6 ANTIGEN; UNCLASSIFIED DRUG; TRANSCRIPTOME;

EID: 85018582872     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aah4573     Document Type: Article
Times cited : (1692)

References (59)
  • 1
    • 84931569658 scopus 로고    scopus 로고
    • Human mononuclear phagocyte system reunited
    • M. Haniffa, V. Bigley, M. Collin, Human mononuclear phagocyte system reunited. Semin. Cell Dev. Biol. 41, 59-69 (2015). doi: 10.1016/j.semcdb.2015.05.004
    • (2015) Semin. Cell Dev. Biol , vol.41 , pp. 59-69
    • Haniffa, M.1    Bigley, V.2    Collin, M.3
  • 2
    • 84900461408 scopus 로고    scopus 로고
    • Development and function of dendritic cell subsets
    • A. Mildner, S. Jung, Development and function of dendritic cell subsets. Immunity 40, 642-656 (2014). doi: 10.1016/j.immuni.2014.04.016
    • (2014) Immunity , vol.40 , pp. 642-656
    • Mildner, A.1    Jung, S.2
  • 3
    • 84913555812 scopus 로고    scopus 로고
    • Defining dendritic cells
    • B. U. Schraml, C. Reis e Sousa, Defining dendritic cells. Curr. Opin. Immunol. 32, 13-20 (2015). doi: 10.1016/j.coi.2014.11.001
    • (2015) Curr. Opin. Immunol , Issue.32 , pp. 13-20
    • Schraml, B.U.1    Sousa R, C.2
  • 4
    • 84942940566 scopus 로고    scopus 로고
    • Defining cell types and states with single-cell genomics
    • C. Trapnell, Defining cell types and states with single-cell genomics. Genome Res. 25, 1491-1498 (2015). doi: 10.1101/gr.190595.115
    • (2015) Genome Res , vol.25 , pp. 1491-1498
    • Trapnell, C.1
  • 5
    • 84946226911 scopus 로고    scopus 로고
    • Design and analysis of single-cell sequencing experiments
    • supplementary materials
    • D. Grön, A. van Oudenaarden, Design and analysis of single-cell sequencing experiments. Cell 163, 799-810 (2015). doi: 10.1016/j.cell.2015.10.039 6. See supplementary materials.
    • (2015) Cell , vol.163 , Issue.6 , pp. 799-810
    • Grön, D.1    Van Oudenaarden, A.2
  • 6
    • 84887101406 scopus 로고    scopus 로고
    • Smart-seq2 for sensitive full-length transcriptome profiling in single cells
    • S. Picelli et al., Smart-seq2 for sensitive full-length transcriptome profiling in single cells. Nat. Methods 10, 1096-1098 (2013). doi: 10.1038/nmeth.2639
    • (2013) Nat. Methods , vol.10 , pp. 1096-1098
    • Picelli, S.1
  • 8
    • 84929684999 scopus 로고    scopus 로고
    • Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
    • E. Z. Macosko et al., Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell 161, 1202-1214 (2015). doi: 10.1016/j.cell.2015.05.002
    • (2015) Cell , vol.161 , pp. 1202-1214
    • Macosko, E.Z.1
  • 9
    • 57249084011 scopus 로고    scopus 로고
    • Visualizing data using t-SNE
    • L. van der Maaten, G. Hinton, Visualizing data using t-SNE. J. Machine Learn. Res. 9, 2579-2605 (2008). www.jmlr.org/papers/volume9/vandermaaten08a/vandermaaten08a.pdf doi: 10.1016/j.cell.2015.05.047
    • (2008) J. Machine Learn. Res , vol.9 , pp. 2579-2605
    • Van der Maaten, L.1    Hinton, G.2
  • 10
    • 84934442835 scopus 로고    scopus 로고
    • Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis
    • J. H. Levine et al., Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis. Cell 162, 184-197 (2015). doi: 10.1016/j.cell.2015.05.047
    • (2015) Cell , vol.162 , pp. 184-197
    • Levine, J.H.1
  • 11
    • 85007467185 scopus 로고    scopus 로고
    • Gene signaturebased mapping of immunological systems and diseases
    • H. Liu, J. Liu, M. Toups, T. Soos, C. Arendt, Gene signaturebased mapping of immunological systems and diseases. BMC Bioinformatics 17, 171 (2016). doi: 10.1186/s12859-016-1012-y
    • (2016) BMC Bioinformatics , vol.17 , pp. 171
    • Liu, H.1    Liu, J.2    Toups, M.3    Soos, T.4    Arendt, C.5
  • 12
    • 77952318708 scopus 로고    scopus 로고
    • A genomic approach to human autoimmune diseases
    • V. Pascual, D. Chaussabel, J. Banchereau, A genomic approach to human autoimmune diseases. Annu. Rev. Immunol. 28, 535-571 (2010). doi: 10.1146/annurev-immunol-030409-101221
    • (2010) Annu. Rev. Immunol , vol.28 , pp. 535-571
    • Pascual, V.1    Chaussabel, D.2    Banchereau, J.3
  • 13
    • 79954576925 scopus 로고    scopus 로고
    • Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases
    • B. Mesko, S. Poliska, L. Nagy, Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases. Trends Mol. Med. 17, 223-233 (2011). doi: 10.1016/j.molmed.2010.12.004
    • (2011) Trends Mol. Med , vol.17 , pp. 223-233
    • Mesko, B.1    Poliska, S.2    Nagy, L.3
  • 14
    • 34249718957 scopus 로고    scopus 로고
    • Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors
    • R. S. Welner et al., Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors. Blood 109, 4825-4931 (2007). doi: 10.1182/blood-2006-08-043810
    • (2007) Blood , vol.109 , pp. 4825-4931
    • Welner, R.S.1
  • 15
    • 32244445715 scopus 로고    scopus 로고
    • A novel dendritic cell subset involved in tumor immunosurveillance
    • J. Taieb et al., A novel dendritic cell subset involved in tumor immunosurveillance. Nat. Med. 12, 214-219 (2006). doi: 10.1038/nm1356
    • (2006) Nat. Med , vol.12 , pp. 214-219
    • Taieb, J.1
  • 16
    • 32244448339 scopus 로고    scopus 로고
    • Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity
    • C. W. Chan et al., Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat. Med. 12, 207-213 (2006). doi: 10.1038/nm1352
    • (2006) Nat. Med , vol.12 , pp. 207-213
    • Chan, C.W.1
  • 17
    • 84937967684 scopus 로고    scopus 로고
    • The multifaceted biology of plasmacytoid dendritic cells
    • M. Swiecki, M. Colonna, The multifaceted biology of plasmacytoid dendritic cells. Nat. Rev. Immunol. 15, 471-485 (2015). doi: 10.1038/nri3865
    • (2015) Nat. Rev. Immunol , vol.15 , pp. 471-485
    • Swiecki, M.1    Colonna, M.2
  • 18
    • 84937458381 scopus 로고    scopus 로고
    • Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells
    • M. Cheng et al., Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells. Sci. Rep. 5, 10752 (2015). doi: 10.1038/srep10752
    • (2015) Sci. Rep , vol.5 , pp. 10752
    • Cheng, M.1
  • 19
    • 67449128181 scopus 로고    scopus 로고
    • CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions
    • T. Matsui et al., CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions. J. Immunol. 182, 6815-6823 (2009). doi: 10.4049/jimmunol.0802008
    • (2009) J. Immunol , vol.182 , pp. 6815-6823
    • Matsui, T.1
  • 20
    • 0030949479 scopus 로고    scopus 로고
    • The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand
    • G. Grouard et al., The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J. Exp. Med. 185, 1101-1111 (1997). doi: 10.1084/jem.185.6.1101
    • (1997) J. Exp. Med , vol.185 , pp. 1101-1111
    • Grouard, G.1
  • 21
    • 84865418665 scopus 로고    scopus 로고
    • Deciphering the transcriptional network of the dendritic cell lineage
    • J. C. Miller et al., Deciphering the transcriptional network of the dendritic cell lineage. Nat. Immunol. 13, 888-899 (2012). doi: 10.1038/ni.2370
    • (2012) Nat. Immunol , vol.13 , pp. 888-899
    • Miller, J.C.1
  • 22
    • 84869395522 scopus 로고    scopus 로고
    • Re(de)fining the dendritic cell lineage
    • A. T. Satpathy, X. Wu, J. C. Albring, K. M. Murphy, Re(de)fining the dendritic cell lineage. Nat. Immunol. 13, 1145-1154 (2012). doi: 10.1038/ni.2467
    • (2012) Nat. Immunol , vol.13 , pp. 1145-1154
    • Satpathy, A.T.1    Wu, X.2    Albring, J.C.3    Murphy, K.M.4
  • 23
    • 84924724513 scopus 로고    scopus 로고
    • Circulating precursors of human CD1c+ and CD141+ dendritic cells
    • G. Breton et al., Circulating precursors of human CD1c+ and CD141+ dendritic cells. J. Exp. Med. 212, 401-413 (2015). doi: 10.1084/jem.20141441
    • (2015) J. Exp. Med , vol.212 , pp. 401-413
    • Breton, G.1
  • 24
    • 84924743273 scopus 로고    scopus 로고
    • Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow
    • J. Lee et al., Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J. Exp Med. 212, 385-399 (2015). doi: 10.1084/jem.20141442
    • (2015) J. Exp Med , vol.212 , pp. 385-399
    • Lee, J.1
  • 25
    • 84940552348 scopus 로고    scopus 로고
    • Defining human dendritic cell progenitors by multiparametric flow cytometry
    • G. Breton, J. Lee, K. Liu, M. C. Nussenzweig, Defining human dendritic cell progenitors by multiparametric flow cytometry. Nat. Protoc. 10, 1407-1422 (2015). doi: 10.1038/nprot.2015.092
    • (2015) Nat. Protoc , vol.10 , pp. 1407-1422
    • Breton, G.1    Lee, J.2    Liu, K.3    Nussenzweig, M.C.4
  • 26
    • 84955164174 scopus 로고    scopus 로고
    • Distinct routes of lineage development reshape the human blood hierarchy across ontogeny
    • F. Notta et al., Distinct routes of lineage development reshape the human blood hierarchy across ontogeny. Science 351, aab2116 (2016). doi: 10.1126/science.aab2116
    • (2016) Science , vol.35 , pp. aab2116
    • Notta, F.1
  • 27
    • 84856738988 scopus 로고    scopus 로고
    • Hematopoiesis: A human perspective
    • S. Doulatov, F. Notta, E. Laurenti, J. E. Dick, Hematopoiesis: A human perspective. Cell Stem Cell 10, 120-136 (2012). doi: 10.1016/j.stem.2012.01.006
    • (2012) Cell Stem Cell , vol.10 , pp. 120-136
    • Doulatov, S.1    Notta, F.2    Laurenti, E.3    Dick, J.E.4
  • 28
    • 56449097442 scopus 로고    scopus 로고
    • Batf3 deficiency reveals a critical role for CD8a+ dendritic cells in cytotoxic T cell immunity
    • K. Hildner et al., Batf3 deficiency reveals a critical role for CD8a+ dendritic cells in cytotoxic T cell immunity. Science 322, 1097-1100 (2008). doi: 10.1126/science.1164206
    • (2008) Science , vol.322 , pp. 1097-1100
    • Hildner, K.1
  • 29
    • 77953484184 scopus 로고    scopus 로고
    • Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8a+ dendritic cells
    • L. F. Poulin et al., Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8a+ dendritic cells. J. Exp. Med. 207, 1261-1271 (2010). doi: 10.1084/jem.20092618
    • (2010) J. Exp. Med , vol.207 , pp. 1261-1271
    • Poulin, L.F.1
  • 30
    • 77953506509 scopus 로고    scopus 로고
    • The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8a+ dendritic cells
    • K. Crozat et al., The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8a+ dendritic cells. J. Exp. Med. 207, 1283-1292 (2010). doi: 10.1084/jem.20100223
    • (2010) J. Exp. Med , vol.207 , pp. 1283-1292
    • Crozat, K.1
  • 31
    • 77953502765 scopus 로고    scopus 로고
    • Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
    • S. L. Jongbloed et al., Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J. Exp. Med. 207, 1247-1260 (2010). doi: 10.1084/jem.20092140
    • (2010) J. Exp. Med , vol.207 , pp. 1247-1260
    • Jongbloed, S.L.1
  • 32
    • 84864293006 scopus 로고    scopus 로고
    • Human tissues contain CD141hi crosspresenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells
    • M. Haniffa et al., Human tissues contain CD141hi crosspresenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells. Immunity 37, 60-73 (2012). doi: 10.1016/j.immuni.2012.04.012
    • (2012) Immunity , vol.37 , pp. 60-73
    • Haniffa, M.1
  • 34
    • 33846441606 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell leukaemia/lymphoma: Towards a well defined entity
    • F. Garnache-Ottou, J. Feuillard, P. Saas, Plasmacytoid dendritic cell leukaemia/lymphoma: Towards a well defined entity? Br. J. Haematol. 136, 539-548 (2007). doi: 10.1111/j.1365-2141.2006.06458.x
    • (2007) Br J. Haematol , vol.136 , pp. 539-548
    • Garnache-Ottou, F.1    Feuillard, J.2    Saas, P.3
  • 35
    • 84905519085 scopus 로고    scopus 로고
    • Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition
    • M. R. Sapienza et al., Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition. Leukemia 28, 1606-1616 (2014). doi: 10.1038/leu.2014.64
    • (2014) Leukemia , vol.28 , pp. 1606-1616
    • Sapienza, M.R.1
  • 36
    • 84896704607 scopus 로고    scopus 로고
    • Characterization of CD56+ dendritic-like cells: A normal counterpart of blastic plasmacytoid dendritic cell neoplasm
    • Y. Osaki et al., Characterization of CD56+ dendritic-like cells: A normal counterpart of blastic plasmacytoid dendritic cell neoplasm? PLOS ONE 8, e81722 (2013). doi: 10.1371/journal. pone.0081722
    • (2013) PLOS ONE , vol.8 , pp. e81722
    • Osaki, Y.1
  • 37
    • 84939945936 scopus 로고    scopus 로고
    • Human BDCA2+CD123+CD56+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset
    • H. Yu et al., Human BDCA2+CD123+CD56+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset. Protein Cell 6, 297-306 (2015). doi: 10.1007/s13238-015-0140-x
    • (2015) Protein Cell , vol.6 , pp. 297-306
    • Yu, H.1
  • 39
    • 81955164775 scopus 로고    scopus 로고
    • Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine
    • K. L. Lewis et al., Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 35, 780-791 (2011). doi: 10.1016/j.immuni.2011.08.013
    • (2011) Immunity , vol.35 , pp. 780-791
    • Lewis, K.L.1
  • 40
    • 84883172356 scopus 로고    scopus 로고
    • Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-And-effacing bacterial pathogens
    • A. T. Satpathy et al., Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-And-effacing bacterial pathogens. Nat. Immunol. 14, 937-948 (2013). doi: 10.1038/ni.2679
    • (2013) Nat. Immunol , vol.14 , pp. 937-948
    • Satpathy, A.T.1
  • 41
    • 84878191150 scopus 로고    scopus 로고
    • IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
    • A. Schlitzer et al., IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983 (2013). doi: 10.1016/j.immuni.2013.04.011
    • (2013) Immunity , vol.38 , pp. 970-983
    • Schlitzer, A.1
  • 42
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103+CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation
    • E. K. Persson et al., IRF4 transcription-factor-dependent CD103+CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 38, 958-969 (2013). doi: 10.1016/j.immuni.2013.03.009
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1
  • 43
    • 84921786419 scopus 로고    scopus 로고
    • Siglec-mediated regulation of immune cell function in disease
    • M. S. Macauley, P. R. Crocker, J. C. Paulson, Siglec-mediated regulation of immune cell function in disease. Nat. Rev. Immunol. 14, 653-666 (2014). doi: 10.1038/nri3737
    • (2014) Nat. Rev. Immunol , vol.14 , pp. 653-666
    • Macauley, M.S.1    Crocker, P.R.2    Paulson, J.C.3
  • 45
    • 84962118425 scopus 로고    scopus 로고
    • Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells
    • T. J. Nowakowski et al., Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells. Cell Stem Cell 18, 591-596 (2016). doi: 10.1016/j.stem.2016.03.012
    • (2016) Cell Stem Cell , vol.18 , pp. 591-596
    • Nowakowski, T.J.1
  • 46
    • 77957085835 scopus 로고    scopus 로고
    • CX3CR1+ CD8a+ dendritic cells are a steadystate population related to plasmacytoid dendritic cells
    • L. Bar-On et al., CX3CR1+ CD8a+ dendritic cells are a steadystate population related to plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 107, 14745-14750 (2010). doi: 10.1073/pnas.1001562107
    • (2010) Proc. Natl. Acad. Sci. U.S.A , vol.107 , pp. 14745-14750
    • Bar-On, L.1
  • 47
    • 84961231186 scopus 로고    scopus 로고
    • Leukemia-Associated activating mutation of Flt3 expands dendritic cells and alters T cell responses
    • C. M. Lau et al., Leukemia-Associated activating mutation of Flt3 expands dendritic cells and alters T cell responses. J. Exp. Med. 213, 415-431 (2016). doi: 10.1084/jem.20150642
    • (2016) J. Exp. Med , vol.213 , pp. 415-431
    • Lau, C.M.1
  • 48
    • 84951746366 scopus 로고    scopus 로고
    • Siglec-1-positive plasmacytoid dendritic cells (pDCs) in human peripheral blood: A semi-mature and myeloid-like subset imbalanced during protective and autoimmune responses
    • T. R. Wilhelm et al., Siglec-1-positive plasmacytoid dendritic cells (pDCs) in human peripheral blood: A semi-mature and myeloid-like subset imbalanced during protective and autoimmune responses. Clin. Immunol. 163, 42-51 (2016). doi: 10.1016/j.clim.2015.12.001
    • (2016) Clin. Immunol , vol.163 , pp. 42-51
    • Wilhelm, T.R.1
  • 49
    • 77954521172 scopus 로고    scopus 로고
    • An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis
    • N. Schwab, A. L. Zozulya, B. C. Kieseier, K. V. Toyka, H. Wiendl, An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis. J. Immunol. 184, 5368-5374 (2010). doi: 10.4049/jimmunol.0903662
    • (2010) J. Immunol , vol.184 , pp. 5368-5374
    • Schwab, N.1    Zozulya, A.L.2    Kieseier, B.C.3    Toyka, K.V.4    Wiendl, H.5
  • 51
    • 84958824501 scopus 로고    scopus 로고
    • A CD2 high-expressing stress-resistant human plasmacytoid dendritic-cell subset
    • C. Bryant et al., A CD2 high-expressing stress-resistant human plasmacytoid dendritic-cell subset. Immunol. Cell Biol. 94, 447-457 (2016). doi: 10.1038/icb.2015.116
    • (2016) Immunol. Cell Biol , vol.94 , pp. 447-457
    • Bryant, C.1
  • 52
    • 0032773794 scopus 로고    scopus 로고
    • Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type i interferon
    • M. Cella et al., Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 5, 919-923 (1999). doi: 10.1038/11360
    • (1999) Nat. Med , vol.5 , pp. 919-923
    • Cella, M.1
  • 53
    • 84976623109 scopus 로고    scopus 로고
    • Immunotherapy: Cancer vaccine triggers antiviral-Type defences
    • J. De Vries, C. Figdor, Immunotherapy: Cancer vaccine triggers antiviral-Type defences. Nature 534, 329-331 (2016). doi: 10.1038/nature18443
    • (2016) Nature , vol.534 , pp. 329-331
    • De Vries, J.1    Figdor, C.2
  • 54
    • 84868608481 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities
    • J. Tel et al., Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood 120, 3936-3944 (2012). doi: 10.1182/blood-2012-06-435941
    • (2012) Blood , vol.120 , pp. 3936-3944
    • Tel, J.1
  • 55
    • 84873460701 scopus 로고    scopus 로고
    • Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients
    • J. Tel et al., Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res. 73, 1063-1075 (2013). doi: 10.1158/0008-5472. CAN-12-2583
    • (2013) Cancer Res , vol.73 , pp. 1063-1075
    • Tel, J.1
  • 56
    • 84859414433 scopus 로고    scopus 로고
    • A 17q12 allele is associated with altered NK cell subsets and function
    • Z. Xia et al., A 17q12 allele is associated with altered NK cell subsets and function. J. Immunol. 188, 3315-3322 (2012). doi: 10.4049/jimmunol.1102775
    • (2012) J. Immunol , vol.188 , pp. 3315-3322
    • Xia, Z.1
  • 57
    • 84896759364 scopus 로고    scopus 로고
    • Common genetic variants modulate pathogensensing responses in human dendritic cells
    • M. N. Lee et al., Common genetic variants modulate pathogensensing responses in human dendritic cells. Science 343, 1246980 (2014). doi: 10.1126/science.1246980
    • (2014) Science , vol.343 , pp. 1246980
    • Lee, M.N.1
  • 58
    • 84903185013 scopus 로고    scopus 로고
    • Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
    • A. K. Shalek et al., Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. Nature 510, 363-369 (2014).
    • (2014) Nature , vol.510 , pp. 363-369
    • Shalek, A.K.1
  • 59
    • 63049112195 scopus 로고    scopus 로고
    • Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation
    • M. Haniffa et al., Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation. J. Exp. Med. 206, 371-385 (2009). doi: 10.1084/jem.20081633
    • (2009) J. Exp. Med , vol.206 , pp. 371-385
    • Haniffa, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.