Integrated genomics reveals convergent transcriptomic networks underlying chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 194, Issue 8, 2016, Pages 948-960

  Kusko, Rebecca L ^a   Brothers, John F ^a   Tedrow, John ^b   Pandit, Kusum ^b   Huleihel, Luai ^b   Perdomo, Catalina ^a   Liu, Gang ^a   Juan Guardela, Brenda ^c   Kass, Daniel ^b   Zhang, Sherry ^a   Lenburg, Marc ^a   Martinez, Fernando ^d   Quackenbush, John ^e   Sciurba, Frank ^b   Limper, Andrew ^f   Geraci, Mark ^g   Yang, Ivana ^g   Schwartz, David A ^g   Beane, Jennifer ^a   Spira, Avrum ^a,h   Kaminski, Naftali ^c   more..

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f MAYO CLINIC   (United States)

^g UNIVERSITY OF COLORADO   (United States)

^h NONE   (United States)

Author keywords

COPD; ILD; IPF; Network; Transcriptome

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MICRORNA; MICRORNA 96; PLATELET DERIVED GROWTH FACTOR A; PROTEIN MDM2; PROTEIN P53; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; I KAPPA B; I KAPPA B BETA; MDM2 PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; NUMB PROTEIN, HUMAN; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR A;

ADULT; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FIBROSING ALVEOLITIS; GENE EXPRESSION; GENE OVEREXPRESSION; GENOMICS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG EMPHYSEMA; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; RNA SEQUENCE; SEQUENCE ALIGNMENT; TRANSCRIPTOMICS; UPREGULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DNA MICROARRAY; EMPHYSEMA; GENE REGULATORY NETWORK; GENETICS; METABOLISM;

ADULT; EMPHYSEMA; FEMALE; GENE REGULATORY NETWORKS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; I-KAPPA B PROTEINS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-MDM2; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84992390530     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201510-2026OC     Document Type: Article

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