Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans

Carcinogenesis

Volumn 39, Issue 11, 2018, Pages 1331-1341

  Xicola, Rosa M ^a   Manojlovic, Zarko ^b,c   Augustus, Gaius J ^d   Kupfer, Sonia S ^e   Emmadi, Rajyasree ^f   Alagiozian Angelova, Victoria ^g   Triche, Tim ^c,h   Salhia, Bodour ^c   Carpten, John ^b,c   Llor, Xavier ^a   Ellis, Nathan A ⁱ  

^a YALE CANCER CENTER   (United States)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^f UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^g Cook County Health and Hospitals System ^*  (United States)

^h VAN ANDEL RESEARCH INSTITUTE   (United States)

ⁱ UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; FAT1 PROTEIN; GLIS1 PROTEIN; PROTEIN; TET1 PROTEIN; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; APC PROTEIN, HUMAN; BCL9L PROTEIN, HUMAN; CADHERIN; DNA BINDING PROTEIN; FAT1 PROTEIN, HUMAN; GATA6 PROTEIN, HUMAN; GLIS1 PROTEIN, HUMAN; MICROSATELLITE DNA; MIXED FUNCTION OXIDASE; ONCOPROTEIN; SOX9 PROTEIN, HUMAN; TET1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; AFRICAN AMERICAN; ARTICLE; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EARLY CANCER; FEMALE; GENE DOSAGE; GENE FREQUENCY; HUMAN; LOSS OF FUNCTION MUTATION; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION RATE; PHENOTYPE; PRIORITY JOURNAL; SOMATIC MUTATION; WHOLE EXOME SEQUENCING; WNT SIGNALING; COLORECTAL TUMOR; COPY NUMBER VARIATION; GENETICS; PATHOLOGY; STATISTICS AND NUMERICAL DATA;

ADENOMATOUS POLYPOSIS COLI PROTEIN; AFRICAN AMERICANS; CADHERINS; COLORECTAL NEOPLASMS; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; GATA6 TRANSCRIPTION FACTOR; HUMANS; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MIDDLE AGED; MIXED FUNCTION OXYGENASES; PROTO-ONCOGENE PROTEINS; SOX9 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; WHOLE EXOME SEQUENCING; WNT SIGNALING PATHWAY;

EID: 85058612181     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgy122     Document Type: Article

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