메뉴 건너뛰기




Volumn 25, Issue 8, 2012, Pages 1128-1139

Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: An adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features

Author keywords

colorectal carcinoma; early onset; signet ring

Indexed keywords

K RAS PROTEIN;

EID: 84864542171     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2012.61     Document Type: Article
Times cited : (239)

References (39)
  • 2
    • 77957363940 scopus 로고    scopus 로고
    • Increasing incidence of rectal cancer in patients aged younger than 40 years: An analysis of the surveillance, epidemiology, and end results database
    • Meyer JE, Narang T, Schnoll-Sussman FH, et al. Increasing incidence of rectal cancer in patients aged younger than 40 years: an analysis of the surveillance, epidemiology, and end results database. Cancer 2010; 116:4354-4359.
    • (2010) Cancer , vol.116 , pp. 4354-4359
    • Meyer, J.E.1    Narang, T.2    Schnoll-Sussman, F.H.3
  • 3
    • 0242348746 scopus 로고    scopus 로고
    • Rates of colon and rectal cancers are increasing in young adults
    • O'Connell JB, Maggard MA, Liu JH, et al. Rates of colon and rectal cancers are increasing in young adults. Am Surg 2003;69:866-872.
    • (2003) Am Surg , vol.69 , pp. 866-872
    • O'Connell, J.B.1    Maggard, M.A.2    Liu, J.H.3
  • 4
    • 0037118715 scopus 로고    scopus 로고
    • Screening for colorectal cancer in adults at average risk: A summary of the evidence for the US. Preventive Services Task Force
    • Pignone M, Rich M, Teutsch SM, et al. Screening for colorectal cancer in adults at average risk: a summary of the evidence for the US. Preventive Services Task Force. Ann Intern Med 2002;137:132-141.
    • (2002) Ann Intern Med , vol.137 , pp. 132-141
    • Pignone, M.1    Rich, M.2    Teutsch, S.M.3
  • 5
    • 0022337788 scopus 로고
    • Is colorectal carcinoma in the young a more deadly disease?
    • D'Onofrio GM, Tan EG. Is colorectal carcinoma in the young a more deadly disease? Aust N Z J Surg 1985;55:537-540.
    • (1985) Aust N Z J Surg , vol.55 , pp. 537-540
    • D'Onofrio, G.M.1    Tan, E.G.2
  • 6
    • 0018717423 scopus 로고
    • Colorectal carcinoma in the first three decades of life
    • Mills SE, Allen Jr MS. Colorectal carcinoma in the first three decades of life. Am J Surg Pathol 1979;3:443-448.
    • (1979) Am J Surg Pathol , vol.3 , pp. 443-448
    • Mills, S.E.1    Allen Jr., M.S.2
  • 8
    • 0031811367 scopus 로고    scopus 로고
    • Colorectal cancer in patients under forty: Presentation and outcome
    • Parramore JB, Wei JP, Yeh KA. Colorectal cancer in patients under forty: presentation and outcome. Am Surg 1998;64:563-567.
    • (1998) Am Surg , vol.64 , pp. 563-567
    • Parramore, J.B.1    Wei, J.P.2    Yeh, K.A.3
  • 9
    • 0024357611 scopus 로고
    • Colorectal cancer in patients younger than 40 years of age
    • Smith C, Butler JA. Colorectal cancer in patients younger than 40 years of age. Dis Colon Rectum 1989;32:843-846.
    • (1989) Dis Colon Rectum , vol.32 , pp. 843-846
    • Smith, C.1    Butler, J.A.2
  • 10
    • 3042651220 scopus 로고    scopus 로고
    • Do young colon cancer patients have worse outcomes?
    • O'Connell JB, Maggard MA, Liu JH, et al. Do young colon cancer patients have worse outcomes? World J Surg 2004;28:558-562.
    • (2004) World J Surg , vol.28 , pp. 558-562
    • O'Connell, J.B.1    Maggard, M.A.2    Liu, J.H.3
  • 11
    • 33847212827 scopus 로고    scopus 로고
    • Colorectal cancer localization in young patients: Should we expand the screening program?
    • Savas N, Dagli U, Akbulut S, et al. Colorectal cancer localization in young patients: should we expand the screening program? Dig Dis Sci 2007;52:798-802.
    • (2007) Dig Dis Sci , vol.52 , pp. 798-802
    • Savas, N.1    Dagli, U.2    Akbulut, S.3
  • 12
    • 63849290407 scopus 로고    scopus 로고
    • Clinical, pathologic, and molecular features of early-onset colorectal carcinoma
    • Yantiss RK, Goodarzi M, Zhou XK, et al. Clinical, pathologic, and molecular features of early-onset colorectal carcinoma. Am J Surg Pathol 2009;33:572-582.
    • (2009) Am J Surg Pathol , vol.33 , pp. 572-582
    • Yantiss, R.K.1    Goodarzi, M.2    Zhou, X.K.3
  • 13
    • 14544300998 scopus 로고    scopus 로고
    • Systematic review of microsatellite instability and colorectal cancer prognosis
    • Popat S, Hubner R, Houlston RS. Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 2005;23:609-618.
    • (2005) J Clin Oncol , vol.23 , pp. 609-618
    • Popat, S.1    Hubner, R.2    Houlston, R.S.3
  • 14
    • 64649096900 scopus 로고    scopus 로고
    • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803
    • Bertagnolli MM, Niedzwiecki D, Compton CC, et al. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. J Clin Oncol 2009; 27:1814-1821.
    • (2009) J Clin Oncol , vol.27 , pp. 1814-1821
    • Bertagnolli, M.M.1    Niedzwiecki, D.2    Compton, C.C.3
  • 15
    • 59149092031 scopus 로고    scopus 로고
    • Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer
    • Wang LM, Kevans D, Mulcahy H, et al. Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer. Am J Surg Pathol 2009;33: 134-141.
    • (2009) Am J Surg Pathol , vol.33 , pp. 134-141
    • Wang, L.M.1    Kevans, D.2    Mulcahy, H.3
  • 16
    • 0035875903 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma
    • Smyrk TC, Watson P, Kaul K, et al. Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma. Cancer 2001;91:2417-2422.
    • (2001) Cancer , vol.91 , pp. 2417-2422
    • Smyrk, T.C.1    Watson, P.2    Kaul, K.3
  • 17
    • 0025424347 scopus 로고
    • Crohn's-like lymphoid reaction and colorectal carcinoma: A potential histologic prognosticator
    • Graham DM, Appelman HD. Crohn's-like lymphoid reaction and colorectal carcinoma: a potential histologic prognosticator. Mod Pathol 1990;3:332-335.
    • (1990) Mod Pathol , vol.3 , pp. 332-335
    • Graham, D.M.1    Appelman, H.D.2
  • 18
    • 79961088717 scopus 로고    scopus 로고
    • Carcinoma of the colon and rectum
    • Bosman FT, Carneiro F, Hruban RH, Theise ND (eds) IARC Press: Lyon, France
    • Hamilton SR, Bosman FT, Boffetta P, et al. Carcinoma of the colon and rectum. In: Bosman FT, Carneiro F, Hruban RH, Theise ND (eds). WHO Classification of Tumors of the Digestive System. IARC Press: Lyon, France, 2010, pp 134-146.
    • (2010) WHO Classification of Tumors of the Digestive System , pp. 134-146
    • Hamilton, S.R.1    Bosman, F.T.2    Boffetta, P.3
  • 19
    • 79954583551 scopus 로고    scopus 로고
    • Serrated polyps of the colon and rectum and serrated polyposis
    • Bosman FT, Carneiro F, Hruban RH, Theise ND (eds) IARC Press: Lyon, France
    • Snover DC, Ahnen DJ, Burt RW, et al. Serrated polyps of the colon and rectum and serrated polyposis. In: Bosman FT, Carneiro F, Hruban RH, Theise ND (eds). WHO Classification of Tumors of the Digestive System. IARC Press: Lyon, France, 2010, pp 160-165.
    • (2010) WHO Classification of Tumors of the Digestive System , pp. 160-165
    • Snover, D.C.1    Ahnen, D.J.2    Burt, R.W.3
  • 20
    • 0036893598 scopus 로고    scopus 로고
    • Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR
    • Suraweera N, Duval A, Reperant M, et al. Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology 2002;123:1804-1811.
    • (2002) Gastroenterology , vol.123 , pp. 1804-1811
    • Suraweera, N.1    Duval, A.2    Reperant, M.3
  • 21
    • 33746092527 scopus 로고    scopus 로고
    • Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: Concept of a 'fusion' pathway to colorectal cancer
    • Jass JR, Baker K, Zlobec I, et al. Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer. Histopathology 2006;49: 121-131.
    • (2006) Histopathology , vol.49 , pp. 121-131
    • Jass, J.R.1    Baker, K.2    Zlobec, I.3
  • 22
    • 20244383592 scopus 로고    scopus 로고
    • Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer
    • Young J, Barker MA, Simms LA, et al. Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer. Clin Gastroenterol Hepatol 2005;3:254-263.
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 254-263
    • Young, J.1    Barker, M.A.2    Simms, L.A.3
  • 23
    • 61949256316 scopus 로고    scopus 로고
    • American college of gastroenterology guidelines for colorectal cancer screening 2009
    • Rex DK, Johnson DA, Anderson JC, et al. American college of gastroenterology guidelines for colorectal cancer screening 2009. Am J Gastroenterol 2009;104: 739-750.
    • (2009) Am J Gastroenterol , vol.104 , pp. 739-750
    • Rex, D.K.1    Johnson, D.A.2    Anderson, J.C.3
  • 24
    • 77958456847 scopus 로고    scopus 로고
    • Low frequency of Lynch syndrome among young patients with nonfamilial colorectal cancer
    • Goel A, Nagasaka T, Spiegel J, et al. Low frequency of Lynch syndrome among young patients with nonfamilial colorectal cancer. Clin Gastroenterol Hepatol 2010;8:966-971.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 966-971
    • Goel, A.1    Nagasaka, T.2    Spiegel, J.3
  • 25
    • 0032941343 scopus 로고    scopus 로고
    • Cancer risk in mutation carriers of DNA-mismatch-repair genes
    • Aarnio M, Sankila R, Pukkala E, et al. Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 1999;81:214-218.
    • (1999) Int J Cancer , vol.81 , pp. 214-218
    • Aarnio, M.1    Sankila, R.2    Pukkala, E.3
  • 26
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 27
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • Bos JL, Fearon ER, Hamilton SR, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-297.
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 28
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319:525-532.
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 29
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass Jr. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007;50:113-130.
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 30
    • 54249165951 scopus 로고    scopus 로고
    • Hypermethylator phenotype in sporadic colon cancer: Study on a population-based series of 582 cases
    • Barault L, Charon-Barra C, Jooste V, et al. Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases. Cancer Res 2008;68:8541-8546.
    • (2008) Cancer Res , vol.68 , pp. 8541-8546
    • Barault, L.1    Charon-Barra, C.2    Jooste, V.3
  • 31
    • 58249089525 scopus 로고    scopus 로고
    • CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
    • Ogino S, Nosho K, Kirkner GJ, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009;58:90-96.
    • (2009) Gut , vol.58 , pp. 90-96
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3
  • 32
    • 41649102270 scopus 로고    scopus 로고
    • Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential
    • Wu JM, Montgomery EA, Iacobuzio-Donahue CA. Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential. Am J Clin Pathol 2008;129:416-423.
    • (2008) Am J Clin Pathol , vol.129 , pp. 416-423
    • Wu, J.M.1    Montgomery, E.A.2    Iacobuzio-Donahue, C.A.3
  • 33
    • 73349134675 scopus 로고    scopus 로고
    • Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
    • Yachida S, Mudali S, Martin SA, et al. Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation. Am J Surg Pathol 2009; 33:1823-1832.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1823-1832
    • Yachida, S.1    Mudali, S.2    Martin, S.A.3
  • 34
    • 44849132638 scopus 로고    scopus 로고
    • Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer
    • Nagasaka T, Koi M, Kloor M, et al. Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer. Gastroenterology 2008;134:1950-1960.
    • (2008) Gastroenterology , vol.134 , pp. 1950-1960
    • Nagasaka, T.1    Koi, M.2    Kloor, M.3
  • 35
    • 34248547049 scopus 로고    scopus 로고
    • Evidence for an association of human papillomavirus infection and colorectal cancer
    • Damin DC, Caetano MB, Rosito MA, et al. Evidence for an association of human papillomavirus infection and colorectal cancer. Eur J Surg Oncol 2007;33: 569-574.
    • (2007) Eur J Surg Oncol , vol.33 , pp. 569-574
    • Damin, D.C.1    Caetano, M.B.2    Rosito, M.A.3
  • 36
    • 17144416826 scopus 로고    scopus 로고
    • Colorectal papillomavirus infection in patients with colorectal cancer
    • Bodaghi S, Yamanegi K, Xiao SY, et al. Colorectal papillomavirus infection in patients with colorectal cancer. Clin Cancer Res 2005;11:2862-2867.
    • (2005) Clin Cancer Res , vol.11 , pp. 2862-2867
    • Bodaghi, S.1    Yamanegi, K.2    Xiao, S.Y.3
  • 37
    • 46249087094 scopus 로고    scopus 로고
    • Risk-reducing total gastrectomy for germline mutations in E-cadherin (CDH1): Pathologic findings with clinical implications
    • Rogers WM, Dobo E, Norton JA, et al. Risk-reducing total gastrectomy for germline mutations in E-cadherin (CDH1): pathologic findings with clinical implications. Am J Surg Pathol 2008;32:799-809.
    • (2008) Am J Surg Pathol , vol.32 , pp. 799-809
    • Rogers, W.M.1    Dobo, E.2    Norton, J.A.3
  • 38
    • 32844456752 scopus 로고    scopus 로고
    • Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component
    • Ogino S, Brahmandam M, Cantor M, et al. Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component. Mod Pathol 2006;19: 59-68.
    • (2006) Mod Pathol , vol.19 , pp. 59-68
    • Ogino, S.1    Brahmandam, M.2    Cantor, M.3
  • 39
    • 13244277935 scopus 로고    scopus 로고
    • Signet ring cell carcinoma of the colorectum: Correlations between microsatellite instability, clinicopathologic features and survival
    • Kakar S, Smyrk TC. Signet ring cell carcinoma of the colorectum: correlations between microsatellite instability, clinicopathologic features and survival. Mod Pathol 2005;18:244-249.
    • (2005) Mod Pathol , vol.18 , pp. 244-249
    • Kakar, S.1    Smyrk, T.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.