Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages

Cancer

Volumn 120, Issue 2, 2014, Pages 172-180

  Fatemi, Mehrnaz ^a   Paul, Thomas A ^b   Brodeur, Garrett M ^c   Shokrani, Babak ^d   Brim, Hassan ^d   Ashktorab, Hassan ^a  

^a HOWARD UNIVERSITY CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

African Americans; CHD5; colon cancer; histone; promoter

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE; DNA; MESSENGER RNA; PROTEIN CHD5; RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VORINOSTAT;

AFRICAN AMERICAN; ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CELL INVASION ASSAY; CELL MIGRATION; CELL PROLIFERATION; CHD5 GENE; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DNA ISOLATION; DNA METHYLATION; EARLY CANCER; EPIGENETICS; GENE EXPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 84891862107     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.28316     Document Type: Article

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