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Volumn 8, Issue , 2008, Pages

The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; CELL PROTEIN; LIGAND; ONCOPROTEIN; PROTEIN B9L; PROTEIN BCL 9; WNT PROTEIN; BCL9 PROTEIN, HUMAN; BCL9L PROTEIN, HUMAN; DNA BINDING PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

EID: 48249127970     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-199     Document Type: Article
Times cited : (102)

References (49)
  • 1
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • 10.1101/gad.11.24.3286 9407023
    • Cadigan KM Nusse R Wnt signaling: A common theme in animal development Genes Dev 1997, 11:3286-3305 10.1101/gad.11.24.3286 9407023
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 2
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • 10.1016/S0092-8674(00)00122-7 11057903
    • Bienz M Clevers H Linking colorectal cancer to Wnt signaling Cell 2000, 103:311-320 10.1016/S0092-8674(00)00122-7 11057903
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 3
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • 10921899
    • Polakis P Wnt signaling and cancer Genes Dev 2000, 14:1837-1851 10921899
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 4
    • 0034678610 scopus 로고    scopus 로고
    • The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
    • 302022 10775268 10.1093/emboj/19.8.1839
    • Hecht A Vleminckx K Stemmler MP van Roy F Kemler R The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates EMBO J 2000, 19:1839-1850 302022 10775268 10.1093/emboj/19.8.1839
    • (2000) EMBO J , vol.19 , pp. 1839-1850
    • Hecht, A.1    Vleminckx, K.2    Stemmler, M.P.3    van Roy, F.4    Kemler, R.5
  • 5
    • 0034678357 scopus 로고    scopus 로고
    • The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
    • 2175158 10769018 10.1083/jcb.149.2.249
    • Takemaru KI Moon RT The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression J Cell Biol 2000, 149:249-254 2175158 10769018 10.1083/jcb.149.2.249
    • (2000) J Cell Biol , vol.149 , pp. 249-254
    • Takemaru, K.I.1    Moon, R.T.2
  • 6
    • 0036754604 scopus 로고    scopus 로고
    • ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules
    • 10.1016/S1097-2765(02)00631-7 12408825
    • Daniels DL Weis WI ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules Mol Cell 2002, 10:573-584 10.1016/ S1097-2765(02)00631-7 12408825
    • (2002) Mol Cell , vol.10 , pp. 573-584
    • Daniels, D.L.1    Weis, W.I.2
  • 7
    • 0035801499 scopus 로고    scopus 로고
    • The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
    • 125268 11532957 10.1093/emboj/20.17.4935
    • Barker N Hurlstone A Musisi H Miles A Bienz M Clevers H The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation EMBO J 2001, 20:4935-4943 125268 11532957 10.1093/emboj/ 20.17.4935
    • (2001) EMBO J , vol.20 , pp. 4935-4943
    • Barker, N.1    Hurlstone, A.2    Musisi, H.3    Miles, A.4    Bienz, M.5    Clevers, H.6
  • 8
    • 0037135602 scopus 로고    scopus 로고
    • Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators
    • 10.1074/jbc.M110865200 11983685
    • Koh SS Li H Lee YH Widelitz RB Chuong CM Stallcup MR Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators J Biol Chem 2002, 277:26031-26035 10.1074/jbc.M110865200 11983685
    • (2002) J Biol Chem , vol.277 , pp. 26031-26035
    • Koh, S.S.1    Li, H.2    Lee, Y.H.3    Widelitz, R.B.4    Chuong, C.M.5    Stallcup, M.R.6
  • 9
    • 33644763022 scopus 로고    scopus 로고
    • The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes
    • 1410807 16510874 10.1101/gad.1385806
    • Sierra J Yoshida T Joazeiro CA Jones KA The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes Genes Dev 2006, 20:586-600 1410807 16510874 10.1101/gad.1385806
    • (2006) Genes Dev , vol.20 , pp. 586-600
    • Sierra, J.1    Yoshida, T.2    Joazeiro, C.A.3    Jones, K.A.4
  • 10
    • 33645646964 scopus 로고    scopus 로고
    • Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1
    • 1626527 16344550 10.1074/jbc.M510403200
    • Yang CK Kim JH Li H Stallcup MR Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1 J Biol Chem 2006, 281:3389-3397 1626527 16344550 10.1074/jbc.M510403200
    • (2006) J Biol Chem , vol.281 , pp. 3389-3397
    • Yang, C.K.1    Kim, J.H.2    Li, H.3    Stallcup, M.R.4
  • 11
    • 0033580842 scopus 로고    scopus 로고
    • Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
    • 10.1074/jbc.274.25.18017 10364252
    • Hecht A Litterst CM Huber O Kemler R Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro J Biol Chem 1999, 274:18017-18025 10.1074/jbc.274.25.18017 10364252
    • (1999) J Biol Chem , vol.274 , pp. 18017-18025
    • Hecht, A.1    Litterst, C.M.2    Huber, O.3    Kemler, R.4
  • 12
    • 0034669058 scopus 로고    scopus 로고
    • Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity
    • 305835 11080158 10.1093/emboj/19.22.6121
    • Bauer A Chauvet S Huber O Usseglio F Rothbacher U Aragnol D Kemler R Pradel J Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity EMBO J 2000, 19:6121-6130 305835 11080158 10.1093/emboj/19.22.6121
    • (2000) EMBO J , vol.19 , pp. 6121-6130
    • Bauer, A.1    Chauvet, S.2    Huber, O.3    Usseglio, F.4    Rothbacher, U.5    Aragnol, D.6    Kemler, R.7    Pradel, J.8
  • 13
    • 33646555522 scopus 로고    scopus 로고
    • Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo
    • 10.1016/j.cell.2006.01.053 16630820
    • Mosimann C Hausmann G Basler K Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/ Armadillo Cell 2006, 125:327-341 10.1016/j.cell.2006.01.053 16630820
    • (2006) Cell , vol.125 , pp. 327-341
    • Mosimann, C.1    Hausmann, G.2    Basler, K.3
  • 17
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • 10.1016/S0092-8674(02)01014-0 12408868
    • Wetering van de M Sancho E Verweij C de Lau W Oving I Hurlstone A Horn van der K Batlle E Coudreuse D Haramis AP et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 2002, 111:241-250 10.1016/S0092-8674(02)01014-0 12408868
    • (2002) Cell , vol.111 , pp. 241-250
    • Wetering, M.1    Sancho, E.2    Verweij, C.3    de Lau, W.4    Oving, I.5    Hurlstone, A.6    Horn, K.7    Batlle, E.8    Coudreuse, D.9    Haramis, A.P.10
  • 20
    • 0037023584 scopus 로고    scopus 로고
    • Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
    • 10.1016/S0092-8674(02)00679-7 11955446
    • Kramps T Peter O Brunner E Nellen D Froesch B Chatterjee S Murone M Zullig S Basler K Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex Cell 2002, 109:47-60 10.1016/S0092-8674(02)00679-7 11955446
    • (2002) Cell , vol.109 , pp. 47-60
    • Kramps, T.1    Peter, O.2    Brunner, E.3    Nellen, D.4    Froesch, B.5    Chatterjee, S.6    Murone, M.7    Zullig, S.8    Basler, K.9
  • 22
    • 0036333382 scopus 로고    scopus 로고
    • Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila
    • 12015286
    • Parker DS Jemison J Cadigan KM Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila Development 2002, 129:2565-2576 12015286
    • (2002) Development , vol.129 , pp. 2565-2576
    • Parker, D.S.1    Jemison, J.2    Cadigan, K.M.3
  • 24
    • 9244233875 scopus 로고    scopus 로고
    • Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling
    • 10.1158/0008-5472.CAN-04-2254 15574752
    • Adachi S Jigami T Yasui T Nakano T Ohwada S Omori Y Sugano S Ohkawara B Shibuya H Nakamura T Akiyama T Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling Cancer Res 2004, 64:8496-8501 10.1158/ 0008-5472.CAN-04-2254 15574752
    • (2004) Cancer Res , vol.64 , pp. 8496-8501
    • Adachi, S.1    Jigami, T.2    Yasui, T.3    Nakano, T.4    Ohwada, S.5    Omori, Y.6    Sugano, S.7    Ohkawara, B.8    Shibuya, H.9    Nakamura, T.10    Akiyama, T.11
  • 25
    • 4444276194 scopus 로고    scopus 로고
    • Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions
    • 517514 15371335 10.1101/gad.317604
    • Brembeck FH Schwarz-Romond T Bakkers J Wilhelm S Hammerschmidt M Birchmeier W Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions Genes Dev 2004, 18:2225-2230 517514 15371335 10.1101/gad.317604
    • (2004) Genes Dev , vol.18 , pp. 2225-2230
    • Brembeck, F.H.1    Schwarz-Romond, T.2    Bakkers, J.3    Wilhelm, S.4    Hammerschmidt, M.5    Birchmeier, W.6
  • 26
    • 0041661953 scopus 로고    scopus 로고
    • Pygopus is required for embryonic brain patterning in Xenopus
    • 10.1016/S0012-1606(03)00305-1 12941625
    • Lake BB Kao KR Pygopus is required for embryonic brain patterning in Xenopus Dev Biol 2003, 261:132-148 10.1016/S0012-1606(03)00305-1 12941625
    • (2003) Dev Biol , vol.261 , pp. 132-148
    • Lake, B.B.1    Kao, K.R.2
  • 28
    • 34247892478 scopus 로고    scopus 로고
    • Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development
    • 1858683 17425782 10.1186/1741-7007-5-15
    • Schwab KR Patterson LT Hartman HA Song N Lang RA Lin X Potter SS Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development BMC Biol 2007, 5:15 1858683 17425782 10.1186/1741-7007-5-15
    • (2007) BMC Biol , vol.5 , pp. 15
    • Schwab, K.R.1    Patterson, L.T.2    Hartman, H.A.3    Song, N.4    Lang, R.A.5    Lin, X.6    Potter, S.S.7
  • 29
    • 34250665417 scopus 로고    scopus 로고
    • Pygopus 2 has a crucial, Wnt pathway-independent function in lens induction
    • 10.1242/dev.001495 17428831
    • Song N Schwab KR Patterson LT Yamaguchi T Lin X Potter SS Lang RA pygopus 2 has a crucial, Wnt pathway-independent function in lens induction Development 2007, 134:1873-1885 10.1242/dev.001495 17428831
    • (2007) Development , vol.134 , pp. 1873-1885
    • Song, N.1    Schwab, K.R.2    Patterson, L.T.3    Yamaguchi, T.4    Lin, X.5    Potter, S.S.6    Lang, R.A.7
  • 30
    • 26944436274 scopus 로고    scopus 로고
    • Dissecting nuclear Wingless signalling: Recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins
    • 10.1016/j.mod.2005.07.004 16169192
    • Stadeli R Basler K Dissecting nuclear Wingless signalling: Recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins Mech Dev 2005, 122:1171-1182 10.1016/j.mod.2005.07.004 16169192
    • (2005) Mech Dev , vol.122 , pp. 1171-1182
    • Stadeli, R.1    Basler, K.2
  • 31
    • 1242317058 scopus 로고    scopus 로고
    • Pygopus residues required for its binding to Legless are critical for transcription and development
    • 10.1074/jbc.M309722200 14612447
    • Townsley FM Thompson B Bienz M Pygopus residues required for its binding to Legless are critical for transcription and development J Biol Chem 2004, 279:5177-5183 10.1074/jbc.M309722200 14612447
    • (2004) J Biol Chem , vol.279 , pp. 5177-5183
    • Townsley, F.M.1    Thompson, B.2    Bienz, M.3
  • 32
    • 4644290995 scopus 로고    scopus 로고
    • Identification and in vivo role of the Armadillo-Legless interaction
    • 10.1242/dev.01296 15294866
    • Hoffmans R Basler K Identification and in vivo role of the Armadillo-Legless interaction Development 2004, 131:4393-4400 10.1242/ dev.01296 15294866
    • (2004) Development , vol.131 , pp. 4393-4400
    • Hoffmans, R.1    Basler, K.2
  • 33
    • 21844437361 scopus 로고    scopus 로고
    • Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin
    • 10.1016/j.cub.2005.05.054 16005293
    • Hoffmans R Stadeli R Basler K Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin Curr Biol 2005, 15:1207-1211 10.1016/j.cub.2005.05.054 16005293
    • (2005) Curr Biol , vol.15 , pp. 1207-1211
    • Hoffmans, R.1    Stadeli, R.2    Basler, K.3
  • 34
    • 3242706980 scopus 로고    scopus 로고
    • Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function
    • 10.1038/ncb1141 15208637
    • Townsley FM Cliffe A Bienz M Pygopus and Legless target Armadillo/ beta-catenin to the nucleus to enable its transcriptional co-activator function Nat Cell Biol 2004, 6:626-633 10.1038/ncb1141 15208637
    • (2004) Nat Cell Biol , vol.6 , pp. 626-633
    • Townsley, F.M.1    Cliffe, A.2    Bienz, M.3
  • 35
    • 33847730861 scopus 로고    scopus 로고
    • Wingless-independent association of Pygopus with dTCF target genes
    • 10.1016/j.cub.2007.01.063 17320388
    • de la Roche M Bienz M Wingless-independent association of Pygopus with dTCF target genes Curr Biol 2007, 17:556-561 10.1016/j.cub.2007.01.063 17320388
    • (2007) Curr Biol , vol.17 , pp. 556-561
    • de la Roche, M.1    Bienz, M.2
  • 36
    • 0032526401 scopus 로고    scopus 로고
    • Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin
    • 2132796 9628899 10.1083/jcb.141.6.1433
    • Simcha I Shtutman M Salomon D Zhurinsky J Sadot E Geiger B Ben-Ze'ev A Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin J Cell Biol 1998, 141:1433-1448 2132796 9628899 10.1083/jcb.141.6.1433
    • (1998) J Cell Biol , vol.141 , pp. 1433-1448
    • Simcha, I.1    Shtutman, M.2    Salomon, D.3    Zhurinsky, J.4    Sadot, E.5    Geiger, B.6    Ben-Ze'ev, A.7
  • 37
    • 0030800831 scopus 로고    scopus 로고
    • Three-dimensional structure of the armadillo repeat region of beta-catenin
    • 10.1016/S0092-8674(00)80352-9 9298899
    • Huber AH Nelson WJ Weis WI Three-dimensional structure of the armadillo repeat region of beta-catenin Cell 1997, 90:871-882 10.1016/ S0092-8674(00)80352-9 9298899
    • (1997) Cell , vol.90 , pp. 871-882
    • Huber, A.H.1    Nelson, W.J.2    Weis, W.I.3
  • 38
    • 0034739023 scopus 로고    scopus 로고
    • The APC tumour suppressor has a nuclear export function
    • 10.1038/35023016 10984057
    • Rosin-Arbesfeld R Townsley F Bienz M The APC tumour suppressor has a nuclear export function Nature 2000, 406:1009-1012 10.1038/35023016 10984057
    • (2000) Nature , vol.406 , pp. 1009-1012
    • Rosin-Arbesfeld, R.1    Townsley, F.2    Bienz, M.3
  • 39
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
    • 10.1126/science.275.5307.1784 9065401
    • Korinek V Barker N Morin PJ van Wichen D de Weger R Kinzler KW Vogelstein B Clevers H Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma Science 1997, 275:1784-1787 10.1126/science.275.5307.1784 9065401
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3    van Wichen, D.4    de Weger, R.5    Kinzler, K.W.6    Vogelstein, B.7    Clevers, H.8
  • 40
    • 33749685412 scopus 로고    scopus 로고
    • Crystal structure of a beta-catenin/BCL9/Tcf4 complex
    • 10.1016/j.molcel.2006.09.001 17052462
    • Sampietro J Dahlberg CL Cho US Hinds TR Kimelman D Xu W Crystal structure of a beta-catenin/BCL9/Tcf4 complex Mol Cell 2006, 24:293-300 10.1016/j.molcel.2006.09.001 17052462
    • (2006) Mol Cell , vol.24 , pp. 293-300
    • Sampietro, J.1    Dahlberg, C.L.2    Cho, U.S.3    Hinds, T.R.4    Kimelman, D.5    Xu, W.6
  • 42
    • 33646583259 scopus 로고    scopus 로고
    • Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention
    • 10.1242/jcs.02864 16554443
    • Krieghoff E Behrens J Mayr B Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention J Cell Sci 2006, 119:1453-1463 10.1242/jcs.02864 16554443
    • (2006) J Cell Sci , vol.119 , pp. 1453-1463
    • Krieghoff, E.1    Behrens, J.2    Mayr, B.3
  • 44
    • 1842430786 scopus 로고    scopus 로고
    • A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes
    • 10.1016/j.cub.2004.02.026 15043810
    • Thompson BJ A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes Curr Biol 2004, 14:458-466 10.1016/j.cub.2004.02.026 15043810
    • (2004) Curr Biol , vol.14 , pp. 458-466
    • Thompson, B.J.1
  • 46
    • 43249100129 scopus 로고    scopus 로고
    • Cell type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin
    • 18347063
    • Sustmann C Flach H Ebert H Eastman Q Grosschedl R Cell type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin Mol Cell Biol 2008 18347063
    • (2008) Mol Cell Biol
    • Sustmann, C.1    Flach, H.2    Ebert, H.3    Eastman, Q.4    Grosschedl, R.5
  • 47
    • 33751342503 scopus 로고    scopus 로고
    • Up-regulation of a BCL9-related beta-catenin-binding protein, B9L, in different stages of sporadic colorectal adenoma
    • 10.1111/j.1349-7006.2006.00363.x 17129358
    • Sakamoto I Ohwada S Toya H Togo N Kashiwabara K Oyama T Nakajima T Ito H Adachi S Jigami T Akiyama T Up-regulation of a BCL9-related beta-catenin-binding protein, B9L, in different stages of sporadic colorectal adenoma Cancer Sci 2007, 98:83-87 10.1111/ j.1349-7006.2006.00363.x 17129358
    • (2007) Cancer Sci , vol.98 , pp. 83-87
    • Sakamoto, I.1    Ohwada, S.2    Toya, H.3    Togo, N.4    Kashiwabara, K.5    Oyama, T.6    Nakajima, T.7    Ito, H.8    Adachi, S.9    Jigami, T.10    Akiyama, T.11
  • 48
    • 0033054464 scopus 로고    scopus 로고
    • The oncogenic activation of beta-catenin
    • 10.1016/S0959-437X(99)80003-3 10072352
    • Polakis P The oncogenic activation of beta-catenin Curr Opin Genet Dev 1999, 9:15-21 10.1016/S0959-437X(99)80003-3 10072352
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 15-21
    • Polakis, P.1
  • 49
    • 0035499603 scopus 로고    scopus 로고
    • Beta-catenin: Molecular plasticity and drug design
    • 10.1016/S0968-0004(01)01952-1 11701326
    • Daniels DL Eklof Spink K Weis WI beta-catenin: Molecular plasticity and drug design Trends Biochem Sci 2001, 26:672-678 10.1016/ S0968-0004(01)01952-1 11701326
    • (2001) Trends Biochem Sci , vol.26 , pp. 672-678
    • Daniels, D.L.1    Eklof Spink, K.2    Weis, W.I.3


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