Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development

Cell Host and Microbe

Volumn 24, Issue 6, 2018, Pages 833-846.e6

  Lee, Yong Soo ^a   Kim, Tae Young ^a   Kim, Yeji ^a   Lee, Su Hyun ^a   Kim, Seungil ^a   Kang, Sung Wan ^a   Yang, Jin Young ^a   Baek, In Jeoung ^b   Sung, Young Hoon ^b   Park, Yun Yong ^b   Hwang, Sung Wook ^b   Eunju, O ^c   Kim, Kwang Soon ^c   Liu, Siqing ^d   Kamada, Nobuhiko ^e   Gao, Nan ^f   Kweon, Mi Na ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

^c Institute for Basic Science   (South Korea)

^d NATIONAL CENTER FOR AGRICULTURAL UTILIZATION RESEARCH   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f RUTGERS UNIVERSITY   (United States)

Author keywords

Gpr81; gut microbiota; intestinal stem cell; lactate; symbiont

Indexed keywords

BETA CATENIN; G PROTEIN COUPLED RECEPTOR 81; LACTATE DEHYDROGENASE; LACTIC ACID; UNCLASSIFIED DRUG; WNT3 PROTEIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN-COUPLED RECEPTOR 81, MOUSE; LGR5 PROTEIN, MOUSE; METHOTREXATE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIFIDOBACTERIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GOBLET CELL; INTESTINAL STEM CELL; INTESTINE EPITHELIUM; INTESTINE FLORA; INTESTINE INJURY; LACTOBACILLUS PLANTARUM; LGR5+ STEM CELL LINE; MALE; MOUSE; NEWBORN; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; REGENERATION; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; STROMA CELL; SYMBIONT; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; GENETICS; HEK293 CELL LINE; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; RADIATION RESPONSE;

ANIMALS; CELL PROLIFERATION; GOBLET CELLS; HEK293 CELLS; HUMANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; LACTOBACILLUS PLANTARUM; METHOTREXATE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; PANETH CELLS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 85057565842     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2018.11.002     Document Type: Article

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