Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

Immunobiology

Volumn 220, Issue 10, 2015, Pages 1161-1169

  Iraporda, Carolina ^a   Errea, Agustina ^b   Romanin, David E ^b   Cayet, Delphine ^c,d,e,f   Pereyra, Elba ^g   Pignataro, Omar ^g,h   Sirard, Jean Claude ^c,d,e,f   Garrote, Graciela L ^a   Abraham, Analía G ^a,i   Rumbo, Martín ^b  

^a CENTRO DE INVESTIGACIÓN Y DESARROLLO EN CRIOTECNOLOGÍA DE ALIMENTOS CIDCA   (Argentina)

^b Universidad Nacional de La Plata   (Argentina)

^c INSERM U1019   (France)

^d INSERM   (France)

^e CNRS   (France)

^f UNIV LILLE   (France)

^g INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^h UNIVERSIDAD DE BUENOS AIRES   (Argentina)

ⁱ FACULTAD DE CIENCIAS EXACTAS   (Argentina)

Author keywords

Immunomodulation; Inflammation; Innate immunity; Lactate; Short chain fatty acids

Indexed keywords

ACETIC ACID; BETA ACTIN; BUTYRIC ACID; CD40 ANTIGEN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 12P40; INTERLEUKIN 6; INTERLEUKIN 8; INTESTINAL TREFOIL FACTOR; LACTIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; PROPIONIC ACID; SHORT CHAIN FATTY ACID; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; FATTY ACID; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW CELL; BONE MARROW DERIVED DENDRITIC CELL; BONE MARROW DERIVED MACROPHAGE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; FEMALE; FERMENTATION; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; LARGE INTESTINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BACTERIUM; CACO 2 CELL LINE; EPITHELIUM CELL; IMMUNOLOGY; INTESTINE MUCOSA; MICROBIOLOGY;

ANIMALS; ANTIGENS, CD40; BACTERIA; CACO-2 CELLS; DOWN-REGULATION; EPITHELIAL CELLS; FATTY ACIDS; FEMALE; HUMANS; INTESTINAL MUCOSA; LACTIC ACID; MICE; MYELOID CELLS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 5;

EID: 84937975894     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.06.004     Document Type: Article

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