메뉴 건너뛰기




Volumn , Issue , 2002, Pages 425-447

Anticonvulsant agents

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85056677830     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (8)

References (135)
  • 1
    • 0033519964 scopus 로고    scopus 로고
    • Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: A multicentre randomised double-blind study. Vigabatrin European Monotherapy Study Group [see comments]
    • Chadwick D. Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study. Vigabatrin European Monotherapy Study Group [see comments]. Lancet 1999; 354:13-19.
    • (1999) Lancet , vol.354 , pp. 13-19
    • Chadwick, D.1
  • 3
    • 0023611675 scopus 로고
    • Carbamazepine side effects in children and adults
    • Pellock JM. Carbamazepine side effects in children and adults. Epilepsia 1987; 28:S64-S70.
    • (1987) Epilepsia , vol.28 , pp. S64-S70
    • Pellock, J.M.1
  • 4
    • 0025165278 scopus 로고
    • Epidemiology of adverse drug reactions to carbamazepine as seen in a spontaneous reporting system
    • Askmark H, Wiholm B. Epidemiology of adverse drug reactions to carbamazepine as seen in a spontaneous reporting system. Acta Neurol Scand 1990; 81:131-140.
    • (1990) Acta Neurol Scand , vol.81 , pp. 131-140
    • Askmark, H.1    Wiholm, B.2
  • 5
    • 0020070132 scopus 로고
    • Drug-induced liver disease in Denmark: An analysis of 572 cases of hepatotoxicity reported to the Danish Board of Adverse Reactions to Drugs
    • Dpssing M, Andreasen PB. Drug-induced liver disease in Denmark: an analysis of 572 cases of hepatotoxicity reported to the Danish Board of Adverse Reactions to Drugs. Scand J Gastroenterol 1982; 17:205-211.
    • (1982) Scand J Gastroenterol , vol.17 , pp. 205-211
    • Dpssing, M.1    Reasen, P.B.2
  • 6
    • 0026755976 scopus 로고
    • Drug-induced hepatic injury: An analysis of 1100 cases reported to the Danish Committee on Adverse Drug Reactions between 1978 and 1987
    • Friis H, Andreasen PB. Drug-induced hepatic injury: an analysis of 1100 cases reported to the Danish Committee on Adverse Drug Reactions between 1978 and 1987. J Intern Med 1992; 232:133-138.
    • (1992) J Intern Med , vol.232 , pp. 133-138
    • Friis, H.1    Reasen, P.B.2
  • 7
    • 0024208020 scopus 로고
    • Anticonvulsant hypersensitivity syndrome: In vitro assessment of risk
    • Shear NH, Spielberg SP. Anticonvulsant hypersensitivity syndrome: in vitro assessment of risk. J Clin Invest 1988; 82:1826-1832.
    • (1988) J Clin Invest , vol.82 , pp. 1826-1832
    • Shear, N.H.1    Spielberg, S.P.2
  • 8
    • 84882657856 scopus 로고    scopus 로고
    • Cytochromes P450 and liver injury
    • RG Cameron, G Feuer, F de la Iglesia, eds., Berlin: Springer-Verlag
    • Pirmohamed M, Park BK. Cytochromes P450 and liver injury. In: RG Cameron, G Feuer, F de la Iglesia, eds. Drug-Induced Hepatotoxicity. Vol. 121. Berlin: Springer-Verlag, 1996: 341-366.
    • (1996) Drug-Induced Hepatotoxicity , vol.121 , pp. 341-366
    • Pirmohamed, M.1    Park, B.K.2
  • 11
    • 0019197074 scopus 로고
    • Granulomatous hepatitis in a patient receiving carbamazepine
    • Levander HG. Granulomatous hepatitis in a patient receiving carbamazepine. Acta Med Scand 1980; 208.
    • (1980) Acta Med Scand , pp. 208
    • Levander, H.G.1
  • 12
    • 0019517762 scopus 로고
    • Fatal carbamazepine-associated hepatitis: Report of 2 cases
    • Hopen G, Nesthus I, Laerum OD. Fatal carbamazepine-associated hepatitis: report of 2 cases. Acta Med Scand 1981; 210:333-335.
    • (1981) Acta Med Scand , vol.210 , pp. 333-335
    • Hopen, G.1    Nesthus, I.2    Laerum, O.D.3
  • 15
    • 0023850919 scopus 로고
    • Extensive carbamazepine eruption with eosino-philia and pulmonary infiltrate
    • Cox NH, Johnston SRD, Marks J, Bates D. Extensive carbamazepine eruption with eosino-philia and pulmonary infiltrate. Postgrad Med J 1988; 64:249-250.
    • (1988) Postgrad Med J , vol.64 , pp. 249-250
    • Cox, N.H.1    Johnston, S.2    Marks, J.3    Bates, D.4
  • 16
    • 0014500525 scopus 로고
    • A case of aplastic anemia and pancytopenia with tegretol therapy
    • Fellows WR. A case of aplastic anemia and pancytopenia with tegretol therapy. Headache 1969; 9:92-95.
    • (1969) Headache , vol.9 , pp. 92-95
    • Fellows, W.R.1
  • 17
    • 0020822597 scopus 로고
    • Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction
    • Ponte CD. Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction. Drug Intell Clin Pharm 1983; 17:642-644.
    • (1983) Drug Intell Clin Pharm , vol.17 , pp. 642-644
    • Ponte, C.D.1
  • 18
    • 0024587634 scopus 로고
    • Carbamazepine-induced granulomatous necrotizing angiitis with acute renal failure
    • Imai H, Nakamoto Y, Hirokawa M, Akihama T, Miura AB. Carbamazepine-induced granulomatous necrotizing angiitis with acute renal failure. Nephron 1989; 51:405-408.
    • (1989) Nephron , vol.51 , pp. 405-408
    • Imai, H.1    Nakamoto, Y.2    Hirokawa, M.3    Akihama, T.4    Miura, A.B.5
  • 20
    • 0019768525 scopus 로고
    • Granulomatous hepatitis associated with carbamazepine therapy
    • Mitchell MC, Boitnott JK, Arregui A, Maddrey WC. Granulomatous hepatitis associated with carbamazepine therapy. Am J Med 1981; 71:733-735.
    • (1981) Am J Med , vol.71 , pp. 733-735
    • Mitchell, M.C.1    Boitnott, J.K.2    Arregui, A.3    Maddrey, W.C.4
  • 21
    • 0026603496 scopus 로고
    • Carbamazepine hepatotoxicity: Another case of the vanishing bile duct syndrome
    • Forbes GM, Jeffrey GP, Shilkin KB, Reed WD. Carbamazepine hepatotoxicity: another case of the vanishing bile duct syndrome. Gastroenterology 1992; 102:1385-1388.
    • (1992) Gastroenterology , vol.102 , pp. 1385-1388
    • Forbes, G.M.1    Jeffrey, G.P.2    Shilkin, K.B.3    Reed, W.D.4
  • 22
    • 0025721852 scopus 로고
    • Carbamazepine-hypersensitivity: Assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine
    • Pirmohamed M, Graham A, Roberts P, Smith D, Chadwick D, Breckenridge AM, Park BK. Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine. Br J Clin Pharmacol 1991; 32:741-749.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 741-749
    • Pirmohamed, M.1    Graham, A.2    Roberts, P.3    Smith, D.4    Chadwick, D.5    Breckenridge, A.M.6    Park, B.K.7
  • 23
    • 0001291927 scopus 로고    scopus 로고
    • Antiepileptic drugs
    • RG Cameron, G Feuer, F de la Iglesia, eds., Berlin: Springer-Verlag
    • Zimmerman HJ, Ishak KG. Antiepileptic drugs. In: RG Cameron, G Feuer, F de la Iglesia, eds. Drug-Induced Hepatotoxicity. Vol. 121. Berlin: Springer-Verlag, 1996:637-662.
    • (1996) Drug-Induced Hepatotoxicity , vol.121 , pp. 637-662
    • Zimmerman, H.J.1    Ishak, K.G.2
  • 25
    • 0344312736 scopus 로고
    • Fatal hepatorenal failure in 3 patients receiving carbamazepine
    • Murphy JV, Francisco CB, Roberts C. Fatal hepatorenal failure in 3 patients receiving carbamazepine. Ann Neurol 1991; 30:276-277.
    • (1991) Ann Neurol , vol.30 , pp. 276-277
    • Murphy, J.V.1    Francisco, C.B.2    Roberts, C.3
  • 26
    • 0023758262 scopus 로고
    • In vitro lymphocyte proliferation by carbamazepine, carbamaze-pine-10,11-epoxide, and oxcarbazepine in the diagnosis of drug-induced hypersensitivity
    • Zakrzewska JM, Ivanyi L. In vitro lymphocyte proliferation by carbamazepine, carbamaze-pine-10,11-epoxide, and oxcarbazepine in the diagnosis of drug-induced hypersensitivity. J Allergy Clin Immunol 1988; 82:110-115.
    • (1988) J Allergy Clin Immunol , vol.82 , pp. 110-115
    • Zakrzewska, J.M.1    Ivanyi, L.2
  • 27
    • 0026727963 scopus 로고
    • Human anti-cytochrome P450 antibodies in aromatic anticonvulsant-induced hypersensitivity reactions
    • Leeder JS, Riley RJ, Cook VA, Spielberg SP. Human anti-cytochrome P450 antibodies in aromatic anticonvulsant-induced hypersensitivity reactions. J Pharmacol Exp Ther 1992; 263: 360-367.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 360-367
    • Leeder, J.S.1    Riley, R.J.2    Cook, V.A.3    Spielberg, S.P.4
  • 28
    • 0026515411 scopus 로고
    • Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity
    • Pirmohamed M, Kitteringham NR, Breckenridge AM, Park BK. Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity. Br J Clin Pharmacol 1992; 33:183-186.
    • (1992) Br J Clin Pharmacol , vol.33 , pp. 183-186
    • Pirmohamed, M.1    Kitteringham, N.R.2    Breckenridge, A.M.3    Park, B.K.4
  • 29
    • 0027304826 scopus 로고
    • Human anti-endoplasmic reticulum antibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
    • Riley RJ, Smith G, Wolf CR, Cook VA, Leeder JS. Human anti-endoplasmic reticulum antibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s). Biochem Biophys Res Commun 1993; 191:32-40.
    • (1993) Biochem Biophys Res Commun , vol.191 , pp. 32-40
    • Riley, R.J.1    Smith, G.2    Wolf, C.R.3    Cook, V.A.4    Leeder, J.S.5
  • 30
    • 0030063547 scopus 로고    scopus 로고
    • Epitope mapping studies with human anti-cytochrome P450 3A antibodies
    • Leeder JS, Gaedigk A, Lu X, Cook VA. Epitope mapping studies with human anti-cytochrome P450 3A antibodies. Mol Pharmacol 1996; 49:234-243.
    • (1996) Mol Pharmacol , vol.49 , pp. 234-243
    • Leeder, J.S.1    Gaedigk, A.2    Lu, X.3    Cook, V.A.4
  • 31
    • 0023938999 scopus 로고
    • Hepatotoxic reactions associated with carbamazepine therapy
    • Horowitz S, Patwardhan R, Marcus E. Hepatotoxic reactions associated with carbamazepine therapy. Epilepsia 1988; 29:149-154.
    • (1988) Epilepsia , vol.29 , pp. 149-154
    • Horowitz, S.1    Patwardhan, R.2    Marcus, E.3
  • 32
    • 0024468706 scopus 로고
    • Pharmacogenetics and cutaneous drug reactions
    • Shear NH, Bhimji S. Pharmacogenetics and cutaneous drug reactions. Semin Dermatol 1988; 8:219-226.
    • (1988) Semin Dermatol , vol.8 , pp. 219-226
    • Shear, N.H.1    Bhimji, S.2
  • 33
    • 0032748789 scopus 로고    scopus 로고
    • Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins
    • Edwards SG, Hubbard V, Aylett S, Wren D. Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins. Postgrad Med J 1999; 75:680-681.
    • (1999) Postgrad Med J , vol.75 , pp. 680-681
    • Edwards, S.G.1    Hubbard, V.2    Aylett, S.3    Wren, D.4
  • 34
    • 0028352066 scopus 로고
    • Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions
    • Gaedigk A, Spielberg SP, Grant DM. Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions. Pharmacogenetics 1994; 4:142-153.
    • (1994) Pharmacogenetics , vol.4 , pp. 142-153
    • Gaedigk, A.1    Spielberg, S.P.2    Grant, D.M.3
  • 36
    • 0035836342 scopus 로고    scopus 로고
    • TNF-alpha promoter region gene polymorphisms in carbamazepine hypersensitive patients
    • Pirmohamed M, Lin K, Chadwick D, Park BK. TNF-alpha promoter region gene polymorphisms in carbamazepine hypersensitive patients. Neurology 2001; 56:890-896.
    • (2001) Neurology , vol.56 , pp. 890-896
    • Pirmohamed, M.1    Lin, K.2    Chadwick, D.3    Park, B.K.4
  • 37
    • 0026503611 scopus 로고
    • An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carba-mazepine in vitro
    • Pirmohamed M, Kitteringham NR, Guenthner TM, Breckenridge AM, Park BK. An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carba-mazepine in vitro. Biochem Pharmacol 1992; 43:1675-1682.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1675-1682
    • Pirmohamed, M.1    Kitteringham, N.R.2    Guenthner, T.M.3    Breckenridge, A.M.4    Park, B.K.5
  • 39
    • 0021965775 scopus 로고
    • Carbamazepine metabolism in man: Induction and pharmacogenetic aspects
    • Eichelbaum M, Thomson T, Tybring G, Bertilsson L. Carbamazepine metabolism in man: induction and pharmacogenetic aspects. Clin Pharmacokin 1985; 10:80-90.
    • (1985) Clin Pharmacokin , vol.10 , pp. 80-90
    • Eichelbaum, M.1    Thomson, T.2    Tybring, G.3    Bertilsson, L.4
  • 41
    • 0029926719 scopus 로고    scopus 로고
    • Bioactivation of carbamazepine in the rat in vivo. Evidence for the formation of reactive arene oxide(s)
    • Madden S, Maggs JL, Park BK. Bioactivation of carbamazepine in the rat in vivo. Evidence for the formation of reactive arene oxide(s). Drug Metab Dispos 1996; 24:469-479.
    • (1996) Drug Metab Dispos , vol.24 , pp. 469-479
    • Madden, S.1    Maggs, J.L.2    Park, B.K.3
  • 43
    • 0026676057 scopus 로고
    • The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver micro-somes
    • Pirmohamed M, Kitteringham NR, Breckenridge AM, Park BK. The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver micro-somes. Biochem Pharmacol 1992; 44:2307-2314.
    • (1992) Biochem Pharmacol , vol.44 , pp. 2307-2314
    • Pirmohamed, M.1    Kitteringham, N.R.2    Breckenridge, A.M.3    Park, B.K.4
  • 47
    • 0032912536 scopus 로고    scopus 로고
    • Detection of 2-hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate
    • Ju C, Uetrecht JP. Detection of 2-hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate. J Pharmacol Exp Ther 1999; 288:51-56.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 51-56
    • Ju, C.1    Uetrecht, J.P.2
  • 48
    • 0031787340 scopus 로고    scopus 로고
    • Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs
    • (suppl 7)
    • Leeder JS. Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs. Epilepsia 1998; 39(suppl 7):S8-S16.
    • (1998) Epilepsia , vol.39 , pp. SS8-S16
    • Leeder, J.S.1
  • 50
    • 0028222385 scopus 로고
    • Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine
    • Friedmann PS, Strickland I, Pirmohamed M, Park BK. Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine. Arch Dermatol 1994; 130:598-604.
    • (1994) Arch Dermatol , vol.130 , pp. 598-604
    • Friedmann, P.S.1    Strickland, I.2    Pirmohamed, M.3    Park, B.K.4
  • 52
    • 0027970864 scopus 로고
    • Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine
    • Isojarvi JIT, Pakarinen AJ, Rautio A, Pelkonen O, Myllyla VV. Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine. Epilepsia 1994; 35:1217-1220.
    • (1994) Epilepsia , vol.35 , pp. 1217-1220
    • Isojarvi, J.1    Pakarinen, A.J.2    Rautio, A.3    Pelkonen, O.4    Myllyla, V.V.5
  • 53
    • 0342910200 scopus 로고
    • Oxcarbazepine in patients hypersensitive to carbamazepine
    • Jensen NO, Dam M, Jakobsen K. Oxcarbazepine in patients hypersensitive to carbamazepine. Irish J Med Sci 1986; 155:297.
    • (1986) Irish J Med Sci , vol.155 , pp. 297
    • Jensen, N.O.1    Dam, M.2    Jakobsen, K.3
  • 54
    • 0027399114 scopus 로고
    • Cross-reactive skin eruption with both carbamazepine and oxcarbazepine
    • Beran RG. Cross-reactive skin eruption with both carbamazepine and oxcarbazepine. Epilepsia 1993; 34:163-165.
    • (1993) Epilepsia , vol.34 , pp. 163-165
    • Beran, R.G.1
  • 55
    • 0018722401 scopus 로고
    • Phenytoin hypersensitivity: 38 cases
    • Haruda F. Phenytoin hypersensitivity: 38 cases. Neurology 1979; 29:1480-1485.
    • (1979) Neurology , vol.29 , pp. 1480-1485
    • Haruda, F.1
  • 56
    • 0018963083 scopus 로고
    • Hepatic injury associated with diphenylhydantoin therapy: A clinico-pathological study of 20 cases
    • Mullick FG, Ishak KG. Hepatic injury associated with diphenylhydantoin therapy: a clinico-pathological study of 20 cases. Am J Clin Pathol 1980; 74:442-452.
    • (1980) Am J Clin Pathol , vol.74 , pp. 442-452
    • Mullick, F.G.1    Ishak, K.G.2
  • 57
    • 0021185974 scopus 로고
    • Enzyme induction by phenobarbitone and vitamin K1 disposition in man
    • Park BK, Wilson AC, Kaatz G, Ohnhaus EE. Enzyme induction by phenobarbitone and vitamin K1 disposition in man. Br J Clin Pharmacol 1984; 18:94-97.
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 94-97
    • Park, B.K.1    Wilson, A.C.2    Kaatz, G.3    Ohnhaus, E.E.4
  • 58
    • 0018963378 scopus 로고
    • The effects of phenobarbital and diphenylhydantoin on liver function and morphology
    • Aiges HW, Daum F, Olson M, Kahn E, Teichberg S. The effects of phenobarbital and diphenylhydantoin on liver function and morphology. J Pediatr 1980; 97:22-26.
    • (1980) J Pediatr , vol.97 , pp. 22-26
    • Aiges, H.W.1    Daum, F.2    Olson, M.3    Kahn, E.4    Teichberg, S.5
  • 61
    • 0021035341 scopus 로고
    • Phenytoin (Diphenylhydantoin) induced hepatotoxicity
    • Masso JFM, Carrera N, Zabalza R, Bengoechea MG. Phenytoin (diphenylhydantoin) induced hepatotoxicity. Med Clin 1983; 81:320-321.
    • (1983) Med Clin , vol.81 , pp. 320-321
    • Masso, J.1    Carrera, N.2    Zabalza, R.3    Bengoechea, M.G.4
  • 62
    • 0024594186 scopus 로고
    • Phenytoin hepatotoxicity: A review of the literature
    • Smythe MA, Umstead GS. Phenytoin hepatotoxicity: a review of the literature. Drug Intell Clin Pharm 1989; 23:13-18.
    • (1989) Drug Intell Clin Pharm , vol.23 , pp. 13-18
    • Smythe, M.A.1    Umstead, G.S.2
  • 63
    • 0023583174 scopus 로고
    • Hepatic considerations in the use of antiepileptic drugs
    • (suppl 2)
    • Dreifuss FE, Langer DH. Hepatic considerations in the use of antiepileptic drugs. Epilepsia 1987; 28(suppl 2):S23-S29.
    • (1987) Epilepsia , vol.28 , pp. S23-S29
    • Dreifuss, F.E.1    Langer, D.H.2
  • 64
    • 0029152762 scopus 로고
    • Hepatotoxicity associated with antiepileptic drug therapy—avoidance, identification and management
    • Bryant AE, Dreifuss FE. Hepatotoxicity associated with antiepileptic drug therapy—avoidance, identification and management. CNS Drugs 1995; 4:9-13.
    • (1995) CNS Drugs , vol.4 , pp. 9-13
    • Bryant, A.E.1    Dreifuss, F.E.2
  • 65
    • 0019509535 scopus 로고
    • Cholestasis and toxic epidermal necrolysis associated with phenytoin sodium: The role of bile duct injury
    • Spechler SJ, Sperber H, Doos WG, Koff RS. Cholestasis and toxic epidermal necrolysis associated with phenytoin sodium: the role of bile duct injury. Ann Intern Med 1981; 95: 455-456.
    • (1981) Ann Intern Med , vol.95 , pp. 455-456
    • Spechler, S.J.1    Sperber, H.2    Doos, W.G.3    Koff, R.S.4
  • 67
    • 0021054282 scopus 로고
    • The phenytoin syndrome
    • Tomsick RS. The phenytoin syndrome. Cutis 1983; 32:535-537.
    • (1983) Cutis , vol.32 , pp. 535-537
    • Tomsick, R.S.1
  • 68
    • 0028793442 scopus 로고
    • Anticonvulsant hypersensitivity syndrome
    • Vittorio CC, Muglia JJ. Anticonvulsant hypersensitivity syndrome. Arch Intern Med 1995; 155:2285-2290.
    • (1995) Arch Intern Med , vol.155 , pp. 2285-2290
    • Vittorio, C.C.1    Muglia, J.J.2
  • 70
    • 0021125859 scopus 로고
    • In vitro assessment of pharmacogenetic susceptibility to toxic drug metabolites in humans
    • Spielberg SP. In vitro assessment of pharmacogenetic susceptibility to toxic drug metabolites in humans. Fed Proc 1984; 43:2308-2313.
    • (1984) Fed Proc , vol.43 , pp. 2308-2313
    • Spielberg, S.P.1
  • 71
    • 0016564943 scopus 로고
    • Severe hypersensitivity to diphenylhydantoin with circulating antibodies to the drug
    • Kleckner HB, Yakulis V, Heller P. Severe hypersensitivity to diphenylhydantoin with circulating antibodies to the drug. Ann Intern Med 1975; 83:522-523.
    • (1975) Ann Intern Med , vol.83 , pp. 522-523
    • Kleckner, H.B.1    Yakulis, V.2    Heller, P.3
  • 73
    • 0030869281 scopus 로고    scopus 로고
    • Bioactivation of phenytoin by human cytochrome P450: Characterization of the mechanism and targets of covalent adduct formation
    • Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EMJ. Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation. Chem Res Toxicol 1997; 10:1049-1058.
    • (1997) Chem Res Toxicol , vol.10 , pp. 1049-1058
    • Munns, A.J.1    De Voss, J.J.2    Hooper, W.D.3    Dickinson, R.G.4    Gillam, E.M.J.5
  • 74
    • 0033854025 scopus 로고    scopus 로고
    • Phenytoin metabolism by human cytochrome P450: Involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation
    • Cuttle L, Munns AJ, Hogg NA, Scott JR, Hooper WD, Dickinson RG, Gillam EMJ. Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation. Drug Metab Dispos 2000; 28: 945-950.
    • (2000) Drug Metab Dispos , vol.28 , pp. 945-950
    • Cuttle, L.1    Munns, A.J.2    Hogg, N.A.3    Scott, J.R.4    Hooper, W.D.5    Dickinson, R.G.6    Gillam, E.M.J.7
  • 75
    • 0033787393 scopus 로고    scopus 로고
    • Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: Roles of cytochromes P450 2C9, 2C19, and 3A4
    • Komatsu T, Yamazaki H, Asahi S, Gillam EMJ, Guengerich FP, Nakajima M, Yokoi T. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4. Drug Metab Dispos 2000; 28:1362-1368.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1362-1368
    • Komatsu, T.1    Yamazaki, H.2    Asahi, S.3    Gillam, E.4    Guengerich, F.P.5    Nakajima, M.6    Yokoi, T.7
  • 77
    • 0030801150 scopus 로고    scopus 로고
    • Cross sensitivity of skin rashes with antiepileptic drugs
    • Hyson C, Sadler M. Cross sensitivity of skin rashes with antiepileptic drugs. Can J Neurol Sci 1997; 24:245-249.
    • (1997) Can J Neurol Sci , vol.24 , pp. 245-249
    • Hyson, C.1    Sadler, M.2
  • 78
    • 0001862416 scopus 로고
    • Valproic acid: Clinical use
    • RH Levy, RH Mattson, BS Meldrum, eds., 4th ed. New York: Raven Press
    • Bourgeois BFD. Valproic acid: clinical use. In: RH Levy, RH Mattson, BS Meldrum, eds. Antiepileptic Drugs. 4th ed. New York: Raven Press, 1995:633-640.
    • (1995) Antiepileptic Drugs , pp. 633-640
    • Bourgeois, B.F.D.1
  • 79
    • 0002118926 scopus 로고
    • Valproic acid: Toxicity
    • RH Levy, RH Mattson, BS Meldrum, eds., 4th ed. New York: Raven Press
    • Dreifuss FE. Valproic acid: toxicity. In: RH Levy, RH Mattson, BS Meldrum, eds. Antiepileptic Drugs. 4th ed. New York: Raven Press, 1995:641-648.
    • (1995) Antiepileptic Drugs , pp. 641-648
    • Dreifuss, F.E.1
  • 80
    • 0018668256 scopus 로고
    • A direct hepatotoxic effect of valproic acid
    • Sussman NM, McLain LW. A direct hepatotoxic effect of valproic acid. JAMA 1979; 242: 1173-1174.
    • (1979) JAMA , vol.242 , pp. 1173-1174
    • Sussman, N.M.1    McLain, L.W.2
  • 81
    • 0020420283 scopus 로고
    • Valproate-induced hepatic injury: Analysis of 23 fatal cases
    • Zimmerman HJ, Ishak KG. Valproate-induced hepatic injury: analysis of 23 fatal cases. Hepatology 1982; 2:591-597.
    • (1982) Hepatology , vol.2 , pp. 591-597
    • Zimmerman, H.J.1    Ishak, K.G.2
  • 84
    • 0024546064 scopus 로고
    • Valproic acid hepatic fatalities. II. US experience since 1984
    • Dreifuss FE, Langer DH, Moline KA, Maxwell JE. Valproic acid hepatic fatalities. II. US experience since 1984. Neurology 1989; 39:201-207.
    • (1989) Neurology , vol.39 , pp. 201-207
    • Dreifuss, F.E.1    Langer, D.H.2    Moline, K.A.3    Maxwell, J.E.4
  • 86
    • 0029925182 scopus 로고    scopus 로고
    • Valproic acid hepatic fatalities. III. U.S. experience since 1986
    • Bryant AE, Dreifuss FE. Valproic acid hepatic fatalities. III. U.S. experience since 1986. Neurology 1996; 46:465-469.
    • (1996) Neurology , vol.46 , pp. 465-469
    • Bryant, A.E.1    Dreifuss, F.E.2
  • 87
    • 0023024205 scopus 로고
    • Valproate toxicity and ornithine carbamoyltransferase deficiency
    • Kay JDS, Hilton-Jones D, Hyman N. Valproate toxicity and ornithine carbamoyltransferase deficiency. Lancet 1986; 2:1283-1284.
    • (1986) Lancet , vol.2 , pp. 1283-1284
    • Kay, J.1    Hilton-Jones, D.2    Hyman, N.3
  • 89
    • 0025783898 scopus 로고
    • Valproate-induced lethal hyperammonemic coma in a carrier of ornithine transcarbamylase deficiency
    • Tokatli A, Coskun S, Cataltepe S, Ozalp I. Valproate-induced lethal hyperammonemic coma in a carrier of ornithine transcarbamylase deficiency. J Inher Metab Dis 1991; 14:836-837.
    • (1991) J Inher Metab Dis , vol.14 , pp. 836-837
    • Tokatli, A.1    Coskun, S.2    Cataltepe, S.3    Ozalp, I.4
  • 90
    • 0026723977 scopus 로고
    • Heterozygotic ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate treatment
    • Honeycutt D, Callahan K, Rutledge L, Wans B. Heterozygotic ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate treatment. Neurology 1992; 42:666.
    • (1992) Neurology , vol.42 , pp. 666
    • Honeycutt, D.1    Callahan, K.2    Rutledge, L.3    Wans, B.4
  • 93
  • 94
    • 84886640030 scopus 로고
    • Valproylcarnitine: A novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry
    • Millington DS, Bohan TP, Roe CR, Yergey AL, Liberato DJ. Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry. Clin Chim Acta 1985; 145:69-76.
    • (1985) Clin Chim Acta , vol.145 , pp. 69-76
    • Millington, D.S.1    Bohan, T.P.2    Roe, C.R.3    Yergey, A.L.4    Liberato, D.J.5
  • 95
    • 0029075379 scopus 로고
    • Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity
    • Krahenbiihl S, Mang G, Kupferschmidt H, Meier PJ, Krause M. Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity. Gut 1995; 37:140-143.
    • (1995) Gut , vol.37 , pp. 140-143
    • Krahenbiihl, S.1    Mang, G.2    Kupferschmidt, H.3    Meier, P.J.4    Krause, M.5
  • 97
    • 0026655249 scopus 로고
    • In vitro effects of valproate and valproate metabolites on mitochondrial oxidations: Relevance of CoA sequestration to the observed inhibitions
    • Ponchaut S, Draye JP, Veitch K. In vitro effects of valproate and valproate metabolites on mitochondrial oxidations: relevance of CoA sequestration to the observed inhibitions. Bio-chem Pharmacol 1992; 43:2435-2442.
    • (1992) Bio-Chem Pharmacol , vol.43 , pp. 2435-2442
    • Ponchaut, S.1    Draye, J.P.2    Veitch, K.3
  • 98
    • 0022270526 scopus 로고
    • Inhibition of medium-chain fatty acid ß-oxidation in vivo by valproic acid and its unsaturated metabolite, 2-w-propyl—4-pentenoic acid
    • Bjorge SM, Baillie TA. Inhibition of medium-chain fatty acid ß-oxidation in vivo by valproic acid and its unsaturated metabolite, 2-w-propyl—4-pentenoic acid. Biochem Biophys Res Commun 1985; 132:245-252.
    • (1985) Biochem Biophys Res Commun , vol.132 , pp. 245-252
    • Bjorge, S.M.1    Baillie, T.A.2
  • 99
    • 0021646542 scopus 로고
    • The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies
    • Kesterson JW, Granneman GR, Machinist JM. The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies. Hepatology 1984; 4:1143-1152.
    • (1984) Hepatology , vol.4 , pp. 1143-1152
    • Kesterson, J.W.1    Granneman, G.R.2    Machinist, J.M.3
  • 100
    • 0021711713 scopus 로고
    • The hepatotoxicity of valproic acid and its metabolites in rats. II. Intermediary and valproic acid metabolism
    • Granneman GR, Wang SI, Kesterson JW, Machinist JM. The hepatotoxicity of valproic acid and its metabolites in rats. II. Intermediary and valproic acid metabolism. Hepatology 1984; 4:1153-1158.
    • (1984) Hepatology , vol.4 , pp. 1153-1158
    • Granneman, G.R.1    Wang, S.I.2    Kesterson, J.W.3    Machinist, J.M.4
  • 101
    • 0020622593 scopus 로고
    • The toxicity of the metabolites of sodium valproate in cultured hepatocytes
    • Kingsley E, Gray PD, Tolman KG, Tweedale R. The toxicity of the metabolites of sodium valproate in cultured hepatocytes. J Clin Pharmacol 1983; 23:178-185.
    • (1983) J Clin Pharmacol , vol.23 , pp. 178-185
    • Kingsley, E.1    Gray, P.D.2    Tolman, K.G.3    Tweedale, R.4
  • 102
    • 0022005538 scopus 로고
    • Studies on the biotransformation in the perfused rat liver of 2-w-propyl-4-pentenoic acid, a metabolite of the antiepileptic drug valproic acid. Evidence for the formation of chemically reactive intermediates
    • Rettenmeier AW, Prickett KS, Gordon WP, Bjorge SM, Chang SL, Levy RH, Baillie TA. Studies on the biotransformation in the perfused rat liver of 2-w-propyl-4-pentenoic acid, a metabolite of the antiepileptic drug valproic acid. Evidence for the formation of chemically reactive intermediates. Drug Metab Dispos 1985; 13:81-96.
    • (1985) Drug Metab Dispos , vol.13 , pp. 81-96
    • Rettenmeier, A.W.1    Prickett, K.S.2    Gordon, W.P.3    Bjorge, S.M.4    Chang, S.L.5    Levy, R.H.6    Baillie, T.A.7
  • 103
    • 0023694528 scopus 로고
    • Metabolic activation of valproic acid and drug-mediated hepatotoxicity. Role of the terminal olefin, 2-w-propyl-4-pentenoic acid
    • Baillie TA. Metabolic activation of valproic acid and drug-mediated hepatotoxicity. Role of the terminal olefin, 2-w-propyl-4-pentenoic acid. Chem Res Toxicol 1988; 1:195-199.
    • (1988) Chem Res Toxicol , vol.1 , pp. 195-199
    • Baillie, T.A.1
  • 107
    • 0029033092 scopus 로고
    • Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture
    • Donato MT, Gomez-Lechon MJ, Castell JV. Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture. Drug Metab Dispos 1995; 23:553-558.
    • (1995) Drug Metab Dispos , vol.23 , pp. 553-558
    • Donato, M.T.1    Gomez-Lechon, M.J.2    Castell, J.V.3
  • 108
    • 0030951908 scopus 로고    scopus 로고
    • Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: Response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines
    • Chang TKH, Maurel P, Waxman DJ. Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines. Cancer Res 1997; 57:1946-1954.
    • (1997) Cancer Res , vol.57 , pp. 1946-1954
    • Chang, T.1    Maurel, P.2    Waxman, D.J.3
  • 110
    • 0026512675 scopus 로고
    • Phenobarbital induction of cytochrome P-450 gene expression
    • Waxman DJ, Azaroff L. Phenobarbital induction of cytochrome P-450 gene expression. Biochem J 1992; 281:577-592.
    • (1992) Biochem J , vol.281 , pp. 577-592
    • Waxman, D.J.1    Azaroff, L.2
  • 111
    • 0031041085 scopus 로고    scopus 로고
    • Pharmacogenetics in pediatrics. Implications for practice
    • Leeder JS, Kearns GL. Pharmacogenetics in pediatrics. Implications for practice. Pediatr Clin North Am 1997; 44:55-77.
    • (1997) Pediatr Clin North Am , vol.44 , pp. 55-77
    • Leeder, J.S.1    Kearns, G.L.2
  • 113
    • 0020589798 scopus 로고
    • Abnormal metabolism of valproic acid in fatal hepatic failure
    • Kochen W, Schneider A, Ritz A. Abnormal metabolism of valproic acid in fatal hepatic failure. Eur J Pediatr 1983; 141:30-35.
    • (1983) Eur J Pediatr , vol.141 , pp. 30-35
    • Kochen, W.1    Schneider, A.2    Ritz, A.3
  • 114
    • 0023120555 scopus 로고
    • Lack of relationship between sodium valproate-induced adverse effects and the plasma concentration of its metabolite 2-propylpenten-4-oic acid
    • Paganini M, Zaccara G, Moroni F, Campostrini R, Bendoni L, Arnetoli G, Zappoli R. Lack of relationship between sodium valproate-induced adverse effects and the plasma concentration of its metabolite 2-propylpenten-4-oic acid. Eur J Clin Pharmacol 1987; 32:219-222.
    • (1987) Eur J Clin Pharmacol , vol.32 , pp. 219-222
    • Paganini, M.1    Zaccara, G.2    Moroni, F.3    Campostrini, R.4    Bendoni, L.5    Arnetoli, G.6    Zappoli, R.7
  • 116
    • 0027522968 scopus 로고
    • Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity
    • Siemes H, Nau H, Schultze K, Wittfoht W, Drews E, Penzien J, Seidel U. Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity. Epilepsia 1993; 34:332-346.
    • (1993) Epilepsia , vol.34 , pp. 332-346
    • Siemes, H.1    Nau, H.2    Schultze, K.3    Wittfoht, W.4    Drews, E.5    Penzien, J.6    Seidel, U.7
  • 117
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial ß-oxidation as a mechanism of hepatotoxicity
    • Fromenty B, Pessayre D. Inhibition of mitochondrial ß-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther 1995; 67:101-154.
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 118
    • 0025971003 scopus 로고
    • Identification and characterization of the glutathione and A-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans
    • Kassahun K, Farrell K, Abbott FS. Identification and characterization of the glutathione and A-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans. Drug Metab Dispos 1991; 19:525-535.
    • (1991) Drug Metab Dispos , vol.19 , pp. 525-535
    • Kassahun, K.1    Farrell, K.2    Abbott, F.S.3
  • 119
    • 0027519432 scopus 로고
    • In vivo formation of the thiol conjugates of reactive metabolites of 4-ene-VPA and its analogue 4-pentenoic acid
    • Kassahun K, Abbott FS. In vivo formation of the thiol conjugates of reactive metabolites of 4-ene-VPA and its analogue 4-pentenoic acid. Drug Metab Dispos 1993; 21:1098-1106.
    • (1993) Drug Metab Dispos , vol.21 , pp. 1098-1106
    • Kassahun, K.1    Abbott, F.S.2
  • 120
    • 0033912868 scopus 로고    scopus 로고
    • Identification and characterization of A-acetylcysteine conjugates of valproic acid in humans and animals
    • Gopaul SV, Farrell K, Abbott FS. Identification and characterization of A-acetylcysteine conjugates of valproic acid in humans and animals. Drug Metab Dispos 2000; 28:823-832.
    • (2000) Drug Metab Dispos , vol.28 , pp. 823-832
    • Gopaul, S.V.1    Farrell, K.2    Abbott, F.S.3
  • 121
    • 0031467511 scopus 로고    scopus 로고
    • Felbamate: 1997 update
    • Pellock JM, Brodie MJ. Felbamate: 1997 update. Epilepsia 1997; 38:1261-1264.
    • (1997) Epilepsia , vol.38 , pp. 1261-1264
    • Pellock, J.M.1    Brodie, M.J.2
  • 124
    • 0029849184 scopus 로고    scopus 로고
    • Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylproprionaldehyde and 2-phenylpropenal: Putative reactive metabolites of felbamate
    • Thompson CD, Kinter MT, Macdonald TL. Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylproprionaldehyde and 2-phenylpropenal: Putative reactive metabolites of felbamate. Chem Res Toxicol 1996; 9:1225-1229.
    • (1996) Chem Res Toxicol , vol.9 , pp. 1225-1229
    • Thompson, C.D.1    Kinter, M.T.2    Macdonald, T.L.3
  • 125
    • 0030975561 scopus 로고    scopus 로고
    • Identification of modified atropaldehyde mercap-turic acids in rat and human urine after felbamate administration
    • Thompson CD, Gulden PH, Macdonald TL. Identification of modified atropaldehyde mercap-turic acids in rat and human urine after felbamate administration. Chem Res Toxicol 1997; 10:457-462.
    • (1997) Chem Res Toxicol , vol.10 , pp. 457-462
    • Thompson, C.D.1    Gulden, P.H.2    Macdonald, T.L.3
  • 127
    • 0029857729 scopus 로고    scopus 로고
    • Lamotrigine: Clinical experience in 200 patients with epilepsy with follow-up to four years
    • Buchanan N. Lamotrigine: clinical experience in 200 patients with epilepsy with follow-up to four years. Seizure 1996; 5:209-214.
    • (1996) Seizure , vol.5 , pp. 209-214
    • Buchanan, N.1
  • 129
    • 0031667163 scopus 로고    scopus 로고
    • Lamotrigine-associated anticonvulsant hypersensitivity syndrome
    • Schlienger RG, Knowles SR, Shear NH. Lamotrigine-associated anticonvulsant hypersensitivity syndrome. Neurology 1998; 51:1172-1175.
    • (1998) Neurology , vol.51 , pp. 1172-1175
    • Schlienger, R.G.1    Knowles, S.R.2    Shear, N.H.3
  • 130
  • 131
  • 132


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.